ClinVar Miner

Variants studied for anaplastic cancer

Included ClinVar conditions (9):
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign other not provided total
16 8 35 22 20 1 1 102

Gene and significance breakdown #

Total genes and gene combinations: 16
Download table as spreadsheet
Gene or gene combination pathogenic likely pathogenic uncertain significance likely benign benign other not provided total
DICER1 9 5 27 22 20 0 1 83
TP53 4 0 0 0 0 0 0 4
PALB2 0 0 2 0 0 0 0 2
AP1B1, ASCC2, CABP7, CASTOR1, CCDC157, DUSP18, EWSR1, GAL3ST1, GAS2L1, HORMAD2, INPP5J, LIF, LIMK2, MORC2, MTFP1, MTMR3, NEFH, NF2, NIPSNAP1, OSBP2, OSM, PATZ1, PES1, PIK3IP1, PLA2G3, RASL10A, RFPL1, RFPL1S, RNF185, RNF215, SEC14L2, SEC14L3, SEC14L4, SEC14L6, SELENOM, SF3A1, SLC35E4, SMTN, TBC1D10A, TCN2, THOC5, TUG1, UQCR10, ZMAT5 0 1 0 0 0 0 0 1
ATRX 1 0 0 0 0 0 0 1
CIC 0 1 0 0 0 0 0 1
KRAS 1 0 0 0 0 0 0 1
LOC107303340, VHL 0 0 1 0 0 0 0 1
LOC110806263, TERT 1 0 0 0 0 0 0 1
MSH6 0 0 1 0 0 0 0 1
PDGFRA 0 0 1 0 0 0 0 1
POT1 0 1 0 0 0 0 0 1
RAD50 0 0 1 0 0 0 0 1
RNF213 0 0 0 0 0 1 0 1
ROS1 0 0 1 0 0 0 0 1
RUNX1 0 0 1 0 0 0 0 1

Submitter and significance breakdown #

Total submitters: 15
Download table as spreadsheet
Submitter pathogenic likely pathogenic uncertain significance likely benign benign other not provided total
KCCC/NGS Laboratory, Kuwait Cancer Control Center 0 0 0 8 16 0 0 24
St. Jude Molecular Pathology, St. Jude Children's Research Hospital 3 0 16 0 0 0 0 19
Illumina Laboratory Services, Illumina 0 0 7 6 4 0 0 17
Fulgent Genetics, Fulgent Genetics 1 0 4 9 1 0 0 15
Salgia Laboratory, City of Hope 4 0 6 0 0 0 0 10
OMIM 6 0 0 0 0 0 0 6
MGZ Medical Genetics Center 0 1 2 0 0 0 0 3
Foulkes Cancer Genetics LDI, Lady Davis Institute for Medical Research 0 2 0 0 0 0 0 2
Genome Sciences Centre, British Columbia Cancer Agency 0 2 0 0 0 0 0 2
Tampere Brain Tumor Research Consortium, University of Tampere 2 0 0 0 0 0 0 2
Donald Williams Parsons Laboratory, Baylor College of Medicine 0 0 0 0 0 1 0 1
Laboratory of Medical Genetics Unit, Bambino Gesù Children's Hospital 0 1 0 0 0 0 0 1
Center for Genomics, Ann and Robert H. Lurie Children's Hospital of Chicago 0 1 0 0 0 0 0 1
GenomeConnect - Invitae Patient Insights Network 0 0 0 0 0 0 1 1
Medizinische Genetik Mainz, Limbach Genetics GmbH 0 1 0 0 0 0 0 1

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.