List of variants reported as pathogenic for bone cancer by Laboratory for Molecular Medicine, Mass General Brigham Personalized Medicine

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Total variants: 15

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HGVS	dbSNP	gnomAD frequency
NM_004985.5(KRAS):c.35G>A (p.Gly12Asp)	rs121913529	0.00001
NM_002524.5(NRAS):c.34G>A (p.Gly12Ser)	rs121913250
NM_002834.5(PTPN11):c.1504T>A (p.Ser502Thr)	rs121918458
NM_002834.5(PTPN11):c.1504T>G (p.Ser502Ala)	rs121918458
NM_002834.5(PTPN11):c.1507G>A (p.Gly503Arg)	rs397507545
NM_002834.5(PTPN11):c.1507G>C (p.Gly503Arg)	rs397507545
NM_002834.5(PTPN11):c.181G>T (p.Asp61Tyr)	rs397507510
NM_002834.5(PTPN11):c.182A>G (p.Asp61Gly)	rs121918461
NM_002834.5(PTPN11):c.184T>G (p.Tyr62Asp)	rs121918460
NM_002834.5(PTPN11):c.226G>A (p.Glu76Lys)	rs121918464
NM_002834.5(PTPN11):c.227A>G (p.Glu76Gly)	rs121918465
NM_002834.5(PTPN11):c.417G>C (p.Glu139Asp)	rs397507520
NM_002834.5(PTPN11):c.417G>T (p.Glu139Asp)	rs397507520
NM_004985.5(KRAS):c.35G>T (p.Gly12Val)	rs121913529
NM_005188.4(CBL):c.1228-2A>G	rs727504426

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