ClinVar Miner

List of variants in gene HNF4A reported as uncertain significance for pancreas disorder

Included ClinVar conditions (165):
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:
Total variants: 260
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HGVS dbSNP gnomAD frequency
NM_175914.5(HNF4A):c.1217-145T>C rs3746574 0.46132
NM_175914.5(HNF4A):c.1217-151A>C rs74173201 0.07406
NM_175914.5(HNF4A):c.*3086C>T rs551080524 0.00706
NM_175914.5(HNF4A):c.393T>C (p.Asn131=) rs113308087 0.00598
NM_175914.5(HNF4A):c.*1127T>C rs757386171 0.00337
NM_175914.5(HNF4A):c.*1078G>A rs573432571 0.00233
NM_175914.5(HNF4A):c.*1293C>T rs182919150 0.00201
NM_175914.5(HNF4A):c.*76G>A rs11574743 0.00191
NM_175914.5(HNF4A):c.*2006T>C rs150112206 0.00175
NM_175914.5(HNF4A):c.*1783G>T rs564110189 0.00161
NM_175914.5(HNF4A):c.*446G>A rs548013860 0.00147
NM_175914.5(HNF4A):c.*1013G>A rs767537996 0.00103
NM_175914.5(HNF4A):c.*3153C>A rs569302875 0.00087
NM_175914.5(HNF4A):c.84G>A (p.Ala28=) rs41282026 0.00084
NM_175914.5(HNF4A):c.426+6G>A rs182980547 0.00070
NM_175914.5(HNF4A):c.1321A>G (p.Ile441Val) rs147638455 0.00061
NM_175914.5(HNF4A):c.*271C>T rs11574745 0.00055
NM_175914.5(HNF4A):c.726G>A (p.Val242=) rs145280017 0.00041
NM_175914.5(HNF4A):c.*2153T>C rs760628227 0.00039
NM_175914.5(HNF4A):c.1176C>T (p.Asn392=) rs141448616 0.00033
NM_175914.5(HNF4A):c.*2992C>T rs770250175 0.00032
NM_175914.5(HNF4A):c.826+30dup rs193922478 0.00031
NM_175914.5(HNF4A):c.*764C>T rs537782818 0.00029
NM_175914.5(HNF4A):c.*1395C>T rs568456380 0.00026
NM_175914.5(HNF4A):c.*547G>A rs1031904976 0.00026
NM_175914.5(HNF4A):c.439G>A (p.Val147Ile) rs142204928 0.00025
NM_175914.5(HNF4A):c.427-4G>A rs146751799 0.00021
NM_175914.5(HNF4A):c.*3013A>G rs773868595 0.00019
NM_175914.5(HNF4A):c.724G>A (p.Val242Met) rs139779712 0.00019
NM_175914.5(HNF4A):c.*1087G>C rs540463510 0.00016
NM_175914.5(HNF4A):c.*2193T>C rs148871044 0.00016
NM_175914.5(HNF4A):c.50-4753G>A rs566155738 0.00016
NM_175914.5(HNF4A):c.582+12C>T rs372596032 0.00016
NM_175914.5(HNF4A):c.*1364G>A rs187923731 0.00014
NM_175914.5(HNF4A):c.*3068C>T rs753843962 0.00014
NM_175914.5(HNF4A):c.*1363C>T rs769165584 0.00013
NM_175914.5(HNF4A):c.*2374G>C rs373068234 0.00011
NM_175914.5(HNF4A):c.*977C>G rs367907885 0.00009
NM_175914.5(HNF4A):c.427-5C>T rs374703326 0.00009
NM_175914.5(HNF4A):c.464G>A (p.Arg155Gln) rs142883089 0.00009
NM_175914.5(HNF4A):c.427-20C>T rs184217112 0.00008
NM_175914.5(HNF4A):c.*3018G>A rs533361991 0.00007
NM_175914.5(HNF4A):c.*1821C>T rs886056686 0.00006
NM_175914.5(HNF4A):c.361A>G (p.Ser121Gly) rs193922472 0.00006
NM_175914.5(HNF4A):c.381G>A (p.Leu127=) rs193922473 0.00006
NM_175914.5(HNF4A):c.624C>T (p.Leu208=) rs759084238 0.00006
NM_175914.5(HNF4A):c.*4G>A rs193922468 0.00005
NM_175914.5(HNF4A):c.1199G>A (p.Arg400Gln) rs202073574 0.00005
NM_175914.5(HNF4A):c.233G>A (p.Arg78Gln) rs371557531 0.00005
NM_175914.5(HNF4A):c.670+7C>T rs376544046 0.00005
NM_175914.5(HNF4A):c.83C>T (p.Ala28Val) rs140143857 0.00005
NM_175914.5(HNF4A):c.*1828G>A rs759101859 0.00004
NM_175914.5(HNF4A):c.*1C>A rs201330472 0.00004
NM_175914.5(HNF4A):c.*2297C>A rs1341485123 0.00004
NM_175914.5(HNF4A):c.1216+6C>A rs778818487 0.00004
NM_175914.5(HNF4A):c.358T>C (p.Ser120Pro) rs780342162 0.00004
NM_175914.5(HNF4A):c.445G>A (p.Gly149Arg) rs747928745 0.00004
NM_175914.5(HNF4A):c.50-4700G>A rs568730599 0.00004
NM_175914.5(HNF4A):c.68G>A (p.Gly23Asp) rs773661614 0.00004
NM_175914.5(HNF4A):c.768G>C (p.Glu256Asp) rs193922477 0.00004
NM_175914.5(HNF4A):c.863G>A (p.Arg288Gln) rs371124358 0.00004
NM_175914.5(HNF4A):c.*1616G>A rs886056685 0.00003
NM_175914.5(HNF4A):c.*168G>T rs1045382698 0.00003
NM_175914.5(HNF4A):c.*2779A>C rs755438203 0.00003
NM_175914.5(HNF4A):c.*572C>A rs761017274 0.00003
NM_175914.5(HNF4A):c.1097C>G (p.Pro366Arg) rs193922469 0.00003
NM_175914.5(HNF4A):c.1144G>A (p.Val382Ile) rs377151067 0.00003
NM_175914.5(HNF4A):c.1300A>G (p.Ile434Val) rs774111430 0.00003
NM_175914.5(HNF4A):c.53C>T (p.Thr18Met) rs199796094 0.00003
NM_175914.5(HNF4A):c.657C>T (p.Asp219=) rs376586083 0.00003
NM_175914.5(HNF4A):c.791A>G (p.Tyr264Cys) rs748714111 0.00003
NM_175914.5(HNF4A):c.*867G>A rs940169046 0.00002
NM_175914.5(HNF4A):c.1020C>G (p.Gly340=) rs758836138 0.00002
NM_175914.5(HNF4A):c.1267C>T (p.Pro423Ser) rs1063239 0.00002
NM_175914.5(HNF4A):c.131G>A (p.Arg44Gln) rs561302824 0.00002
NM_175914.5(HNF4A):c.841A>G (p.Ser281Gly) rs201777208 0.00002
NM_175914.5(HNF4A):c.*2511A>G rs1277613130 0.00001
NM_175914.5(HNF4A):c.*2558T>C rs886056688 0.00001
NM_175914.5(HNF4A):c.*2639T>G rs886056690 0.00001
NM_175914.5(HNF4A):c.*3120T>C rs886056704 0.00001
NM_175914.5(HNF4A):c.*765G>A rs886056681 0.00001
NM_175914.5(HNF4A):c.*782G>A rs886056682 0.00001
NM_175914.5(HNF4A):c.1069C>G (p.Pro357Ala) rs201319115 0.00001
NM_175914.5(HNF4A):c.106G>A (p.Ala36Thr) rs376906221 0.00001
NM_175914.5(HNF4A):c.1138G>A (p.Val380Ile) rs137853337 0.00001
NM_175914.5(HNF4A):c.1177G>A (p.Gly393Arg) rs757897768 0.00001
NM_175914.5(HNF4A):c.1198C>T (p.Arg400Ter) rs1413742263 0.00001
NM_175914.5(HNF4A):c.1243C>T (p.Pro415Ser) rs150776703 0.00001
NM_175914.5(HNF4A):c.196G>A (p.Val66Met) rs369182343 0.00001
NM_175914.5(HNF4A):c.232C>T (p.Arg78Trp) rs780813696 0.00001
NM_175914.5(HNF4A):c.321C>T (p.Ala107=) rs138290205 0.00001
NM_175914.5(HNF4A):c.341G>A (p.Arg114Gln) rs149611886 0.00001
NM_175914.5(HNF4A):c.454G>A (p.Gly152Ser) rs760038979 0.00001
NM_175914.5(HNF4A):c.481A>G (p.Ser161Gly) rs779555087 0.00001
NM_175914.5(HNF4A):c.562G>A (p.Glu188Lys) rs771156648 0.00001
NM_175914.5(HNF4A):c.582+4A>G rs376287515 0.00001
NM_175914.5(HNF4A):c.587C>A (p.Ala196Asp) rs1032164393 0.00001
NM_175914.5(HNF4A):c.714G>C (p.Glu238Asp) rs1259110384 0.00001
NM_175914.5(HNF4A):c.723G>C (p.Arg241=) rs372639360 0.00001
NM_175914.5(HNF4A):c.76C>A (p.Leu26Ile) rs753285226 0.00001
NM_175914.5(HNF4A):c.844G>A (p.Asp282Asn) rs145902391 0.00001
NM_175914.5(HNF4A):c.862C>T (p.Arg288Trp) rs768263630 0.00001
NM_175914.5(HNF4A):c.901A>G (p.Ile301Val) rs920346355 0.00001
NM_175914.5(HNF4A):c.925C>T (p.Arg309Cys) rs193922479 0.00001
NM_175914.5(HNF4A):c.*1089del rs749515492
NM_175914.5(HNF4A):c.*1106G>A rs753675648
NM_175914.5(HNF4A):c.*1291TCCTCCCT[1] rs3834658
NM_175914.5(HNF4A):c.*145T>A rs200905283
NM_175914.5(HNF4A):c.*1809C>G rs2063876979
NM_175914.5(HNF4A):c.*1826G>A rs1763003018
NM_175914.5(HNF4A):c.*2167T>G rs886056687
NM_175914.5(HNF4A):c.*217C>T rs1019701119
NM_175914.5(HNF4A):c.*226C>A rs886056680
NM_175914.5(HNF4A):c.*2600T>C rs886056689
NM_175914.5(HNF4A):c.*2674_*2675del rs886056691
NM_175914.5(HNF4A):c.*2676dup rs886056692
NM_175914.5(HNF4A):c.*2677_*2683del rs886056693
NM_175914.5(HNF4A):c.*2677dup rs886056694
NM_175914.5(HNF4A):c.*2678_*2679insTT rs761222838
NM_175914.5(HNF4A):c.*2678dup rs761222838
NM_175914.5(HNF4A):c.*2679del rs886056695
NM_175914.5(HNF4A):c.*2698_*2703dup rs11450239
NM_175914.5(HNF4A):c.*2698_*2704del rs886056697
NM_175914.5(HNF4A):c.*2703del rs11450239
NM_175914.5(HNF4A):c.*2703dup rs11450239
NM_175914.5(HNF4A):c.*2707del rs886056698
NM_175914.5(HNF4A):c.*2707dup rs886056699
NM_175914.5(HNF4A):c.*2761G>C rs1212257046
NM_175914.5(HNF4A):c.*2777del rs886056700
NM_175914.5(HNF4A):c.*2782A>C rs1192263020
NM_175914.5(HNF4A):c.*2796AC[1] rs548863430
NM_175914.5(HNF4A):c.*3024C>T rs886056702
NM_175914.5(HNF4A):c.*3052G>A rs546761850
NM_175914.5(HNF4A):c.*3104A>C rs886056703
NM_175914.5(HNF4A):c.*35C>A rs1019496764
NM_175914.5(HNF4A):c.*965G>T rs886056683
NM_175914.5(HNF4A):c.*987G>T rs886056684
NM_175914.5(HNF4A):c.*993G>A rs2063867733
NM_175914.5(HNF4A):c.101T>A (p.Val34Asp) rs2063496235
NM_175914.5(HNF4A):c.1063+120G>A
NM_175914.5(HNF4A):c.1063G>A (p.Gly355Arg) rs1568741527
NM_175914.5(HNF4A):c.1064-19C>A rs202202465
NM_175914.5(HNF4A):c.10G>A (p.Val4Met)
NM_175914.5(HNF4A):c.1118A>G (p.Gln373Arg)
NM_175914.5(HNF4A):c.1126A>G (p.Met376Val)
NM_175914.5(HNF4A):c.1127T>G (p.Met376Arg) rs199956600
NM_175914.5(HNF4A):c.1139T>G (p.Val380Gly)
NM_175914.5(HNF4A):c.1151_1162del (p.Asn384_Pro387del)
NM_175914.5(HNF4A):c.1185G>A (p.Met395Ile)
NM_175914.5(HNF4A):c.1187G>C (p.Cys396Ser) rs193922470
NM_175914.5(HNF4A):c.1196C>T (p.Pro399Leu)
NM_175914.5(HNF4A):c.1208G>A (p.Gly403Glu)
NM_175914.5(HNF4A):c.1208G>T (p.Gly403Val)
NM_175914.5(HNF4A):c.1250G>A (p.Gly417Asp)
NM_175914.5(HNF4A):c.1283C>G (p.Pro428Arg)
NM_175914.5(HNF4A):c.1283C>T (p.Pro428Leu)
NM_175914.5(HNF4A):c.128A>G (p.Asp43Gly)
NM_175914.5(HNF4A):c.1290C>T (p.Ala430=) rs530389600
NM_175914.5(HNF4A):c.1291G>A (p.Val431Ile)
NM_175914.5(HNF4A):c.1303G>A (p.Val435Ile) rs145314165
NM_175914.5(HNF4A):c.1306A>T (p.Lys436Ter)
NM_175914.5(HNF4A):c.1309C>A (p.Pro437Thr) rs2063853373
NM_175914.5(HNF4A):c.1312C>A (p.Leu438Ile)
NM_175914.5(HNF4A):c.1331C>T (p.Pro444Leu)
NM_175914.5(HNF4A):c.1348G>A (p.Glu450Lys)
NM_175914.5(HNF4A):c.194G>A (p.Ser65Asn)
NM_175914.5(HNF4A):c.195C>A (p.Ser65Arg) rs1008906897
NM_175914.5(HNF4A):c.199C>A (p.Arg67=)
NM_175914.5(HNF4A):c.203A>G (p.Lys68Arg)
NM_175914.5(HNF4A):c.209A>G (p.His70Arg)
NM_175914.5(HNF4A):c.212T>G (p.Met71Arg)
NM_175914.5(HNF4A):c.221G>A (p.Cys74Tyr) rs1555813342
NM_175914.5(HNF4A):c.224+17dup rs371937621
NM_175914.5(HNF4A):c.224G>A (p.Arg75Lys) rs1131692187
NM_175914.5(HNF4A):c.225-21A>G
NM_175914.5(HNF4A):c.240C>G (p.Cys80Trp)
NM_175914.5(HNF4A):c.241G>T (p.Val81Leu)
NM_175914.5(HNF4A):c.272G>A (p.Arg91His)
NM_175914.5(HNF4A):c.287A>G (p.Lys96Arg)
NM_175914.5(HNF4A):c.28G>C (p.Ala10Pro)
NM_175914.5(HNF4A):c.297C>G (p.Phe99Leu)
NM_175914.5(HNF4A):c.2T>C (p.Met1Thr) rs1229650809
NM_175914.5(HNF4A):c.302C>A (p.Ala101Asp)
NM_175914.5(HNF4A):c.305G>A (p.Gly102Asp)
NM_175914.5(HNF4A):c.322G>T (p.Val108Phe)
NM_175914.5(HNF4A):c.337G>C (p.Asp113His)
NM_175914.5(HNF4A):c.337G>T (p.Asp113Tyr)
NM_175914.5(HNF4A):c.407C>T (p.Ala136Val)
NM_175914.5(HNF4A):c.422G>A (p.Arg141Gln) rs765237979
NM_175914.5(HNF4A):c.426G>A (p.Gln142=)
NM_175914.5(HNF4A):c.426G>C (p.Gln142His)
NM_175914.5(HNF4A):c.427A>G (p.Ile143Val) rs368759794
NM_175914.5(HNF4A):c.460A>T (p.Ile154Phe)
NM_175914.5(HNF4A):c.461T>G (p.Ile154Ser)
NM_175914.5(HNF4A):c.463C>G (p.Arg155Gly)
NM_175914.5(HNF4A):c.463C>T (p.Arg155Trp)
NM_175914.5(HNF4A):c.470AGA[1] (p.Lys158del) rs1280663753
NM_175914.5(HNF4A):c.50-4560G>A rs1254732171
NM_175914.5(HNF4A):c.50-4560G>T rs1254732171
NM_175914.5(HNF4A):c.50-4589G>A
NM_175914.5(HNF4A):c.50-4630T>C rs2063407237
NM_175914.5(HNF4A):c.50-4682C>T
NM_175914.5(HNF4A):c.50-4791_50-4788del rs886056679
NM_175914.5(HNF4A):c.500A>C (p.Glu167Ala)
NM_175914.5(HNF4A):c.502T>C (p.Ser168Pro)
NM_175914.5(HNF4A):c.514C>A (p.Gln172Lys)
NM_175914.5(HNF4A):c.530T>A (p.Val177Asp)
NM_175914.5(HNF4A):c.530T>C (p.Val177Ala) rs2146417574
NM_175914.5(HNF4A):c.534G>T (p.Glu178Asp)
NM_175914.5(HNF4A):c.535T>C (p.Trp179Arg)
NM_175914.5(HNF4A):c.536G>C (p.Trp179Ser)
NM_175914.5(HNF4A):c.539C>A (p.Ala180Asp)
NM_175914.5(HNF4A):c.539C>T (p.Ala180Val)
NM_175914.5(HNF4A):c.553G>C (p.Ala185Pro) rs193922474
NM_175914.5(HNF4A):c.561C>G (p.Cys187Trp)
NM_175914.5(HNF4A):c.577G>A (p.Asp193Asn)
NM_175914.5(HNF4A):c.583-19T>A
NM_175914.5(HNF4A):c.589C>A (p.Leu197Met) rs1775879070
NM_175914.5(HNF4A):c.590T>C (p.Leu197Pro) rs1555816279
NM_175914.5(HNF4A):c.593T>G (p.Leu198Arg) rs1568735272
NM_175914.5(HNF4A):c.601C>T (p.His201Tyr)
NM_175914.5(HNF4A):c.607G>A (p.Gly203Ser) rs2146437968
NM_175914.5(HNF4A):c.609C>T (p.Gly203=)
NM_175914.5(HNF4A):c.610G>A (p.Glu204Lys) rs753476712
NM_175914.5(HNF4A):c.617T>C (p.Leu206Pro)
NM_175914.5(HNF4A):c.622C>T (p.Leu208Phe)
NM_175914.5(HNF4A):c.640T>A (p.Ser214Thr) rs1060499693
NM_175914.5(HNF4A):c.640T>G (p.Ser214Ala)
NM_175914.5(HNF4A):c.641C>A (p.Ser214Tyr)
NM_175914.5(HNF4A):c.641C>T (p.Ser214Phe)
NM_175914.5(HNF4A):c.643A>G (p.Met215Val)
NM_175914.5(HNF4A):c.655G>A (p.Asp219Asn)
NM_175914.5(HNF4A):c.670+18C>A rs751211080
NM_175914.5(HNF4A):c.670+5G>C rs1568735505
NM_175914.5(HNF4A):c.677A>T (p.Asp226Val)
NM_175914.5(HNF4A):c.691C>T (p.Arg231Trp) rs376013528
NM_175914.5(HNF4A):c.702G>A (p.Pro234=)
NM_175914.5(HNF4A):c.707T>G (p.Leu236Arg)
NM_175914.5(HNF4A):c.710C>T (p.Ala237Val)
NM_175914.5(HNF4A):c.716T>C (p.Met239Thr)
NM_175914.5(HNF4A):c.731T>C (p.Ile244Thr)
NM_175914.5(HNF4A):c.763C>G (p.Gln255Glu) rs137853334
NM_175914.5(HNF4A):c.767A>C (p.Glu256Ala)
NM_175914.5(HNF4A):c.778G>T (p.Asp260Tyr) rs1236613475
NM_175914.5(HNF4A):c.789G>C (p.Glu263Asp) rs1568736971
NM_175914.5(HNF4A):c.7A>C (p.Ser3Arg)
NM_175914.5(HNF4A):c.911G>A (p.Arg304His)
NM_175914.5(HNF4A):c.925C>A (p.Arg309Ser) rs193922479
NM_175914.5(HNF4A):c.926G>T (p.Arg309Leu) rs369429452
NM_175914.5(HNF4A):c.928G>A (p.Gly310Ser)
NM_175914.5(HNF4A):c.932G>A (p.Arg311His) rs1375557127
NM_175914.5(HNF4A):c.937G>A (p.Gly313Arg)
NM_175914.5(HNF4A):c.944TGC[4] (p.Leu319del) rs776489992
NM_175914.5(HNF4A):c.944TGC[7] (p.Leu319_Pro320insLeuLeu)
NM_175914.5(HNF4A):c.949C>G (p.Leu317Val)
NM_175914.5(HNF4A):c.950T>C (p.Leu317Pro)
NM_175914.5(HNF4A):c.965T>G (p.Leu322Trp) rs2146468795
NM_175914.5(HNF4A):c.991G>A (p.Glu331Lys)
NM_175914.5(HNF4A):c.999C>G (p.Ile333Met)
Single allele

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