List of variants in gene APC reported as likely benign for colorectal carcinoma

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 26

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HGVS	dbSNP	gnomAD frequency
NM_000038.6(APC):c.4420G>A (p.Ala1474Thr)	rs139387758	0.00324
NM_000038.6(APC):c.4893T>C (p.Ser1631=)	rs35634377	0.00268
NM_000038.6(APC):c.8068G>A (p.Ala2690Thr)	rs140868933	0.00146
NM_000038.6(APC):c.6921G>A (p.Ser2307=)	rs2229993	0.00143
NM_000038.6(APC):c.1825G>A (p.Val609Ile)	rs147863331	0.00096
NM_000038.6(APC):c.6821C>T (p.Ala2274Val)	rs34919187	0.00088
NM_000038.6(APC):c.4336G>A (p.Ala1446Thr)	rs146572883	0.00056
NM_000038.6(APC):c.295C>T (p.Arg99Trp)	rs139196838	0.00048
NM_000038.6(APC):c.6526T>C (p.Leu2176=)	rs183468041	0.00023
NM_000038.6(APC):c.3006C>T (p.Ala1002=)	rs72541810	0.00020
NM_000038.6(APC):c.2205G>A (p.Ala735=)	rs141001261	0.00019
NM_000038.6(APC):c.3374T>C (p.Val1125Ala)	rs377278397	0.00018
NM_000038.6(APC):c.5009C>T (p.Ala1670Val)	rs202228932	0.00018
NM_000038.6(APC):c.450A>G (p.Lys150=)	rs116020626	0.00012
NM_000038.6(APC):c.6873A>T (p.Gln2291His)	rs148878262	0.00012
NM_000038.6(APC):c.2586C>G (p.Asn862Lys)	rs147972247	0.00009
NM_000038.6(APC):c.3786T>C (p.Tyr1262=)	rs147411334	0.00009
NM_000038.6(APC):c.3624C>T (p.Thr1208=)	rs730882125	0.00007
NM_000038.6(APC):c.1005A>G (p.Leu335=)	rs3797704	0.00006
NM_000038.6(APC):c.3876G>A (p.Thr1292=)	rs377494451	0.00004
NM_000038.6(APC):c.6135C>T (p.Ser2045=)	rs187297940	0.00004
NM_000038.6(APC):c.3378C>G (p.Ser1126Arg)	rs149353082	0.00001
NM_000038.6(APC):c.5901C>T (p.Ser1967=)	rs1561603572	0.00001
NM_000038.6(APC):c.6081C>T (p.Leu2027=)	rs1316220949
NM_000038.6(APC):c.620G>A (p.Cys207Tyr)	rs1268298845
NM_000038.6(APC):c.777G>T (p.Arg259=)	rs147704593

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