List of variants in gene POLE reported as likely benign for colorectal carcinoma

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Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 16

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HGVS	dbSNP	gnomAD frequency
NM_006231.4(POLE):c.91G>T (p.Ala31Ser)	rs34047482	0.01320
NM_006231.4(POLE):c.776G>A (p.Arg259His)	rs61732929	0.00604
NM_006231.4(POLE):c.5135C>T (p.Ala1712Val)	rs5744950	0.00346
NM_006231.4(POLE):c.2468+10C>T	rs5744823	0.00342
NM_006231.4(POLE):c.4184A>G (p.Tyr1395Cys)	rs5744933	0.00240
NM_006231.4(POLE):c.4523G>A (p.Arg1508His)	rs142508245	0.00170
NM_006231.4(POLE):c.6453C>T (p.Tyr2151=)	rs116076060	0.00167
NM_006231.4(POLE):c.5124C>T (p.Phe1708=)	rs114891564	0.00149
NM_006231.4(POLE):c.1347G>A (p.Thr449=)	rs142373951	0.00094
NM_006231.4(POLE):c.3851G>A (p.Arg1284Gln)	rs149462407	0.00068
NM_006231.4(POLE):c.6495C>T (p.Arg2165=)	rs114778730	0.00053
NM_006231.4(POLE):c.5496T>C (p.Leu1832=)	rs147543146	0.00029
NM_006231.4(POLE):c.3913G>A (p.Gly1305Arg)	rs563990655	0.00002
NM_006231.4(POLE):c.5481G>A (p.Ser1827=)	rs775867327	0.00002
NM_006231.4(POLE):c.1795-13G>A	rs749522265	0.00001
NM_006231.4(POLE):c.5570A>G (p.Lys1857Arg)	rs5744971

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