List of variants in gene PRKCD reported as uncertain significance for type IV hypersensitivity disease

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 168

Download table as spreadsheet

HGVS	dbSNP	gnomAD frequency
NM_006254.4(PRKCD):c.1447C>T (p.Arg483Trp)	rs35891605	0.00063
NM_006254.4(PRKCD):c.1352+4C>T	rs202155309	0.00019
NM_006254.4(PRKCD):c.1260+7G>A	rs374605708	0.00011
NM_006254.4(PRKCD):c.1706G>A (p.Arg569His)	rs138712106	0.00009
NM_006254.4(PRKCD):c.787+4C>T	rs575167797	0.00009
NM_006254.4(PRKCD):c.949G>A (p.Glu317Lys)	rs55929201	0.00009
NM_006254.4(PRKCD):c.961G>A (p.Gly321Arg)	rs372047510	0.00006
NM_006254.4(PRKCD):c.44G>C (p.Gly15Ala)	rs369358922	0.00004
NM_006254.4(PRKCD):c.1342T>A (p.Tyr448Asn)	rs141979341	0.00003
NM_006254.4(PRKCD):c.657+3G>A	rs199785209	0.00003
NM_006254.4(PRKCD):c.715A>G (p.Met239Val)	rs369236318	0.00003
NM_006254.4(PRKCD):c.799A>C (p.Asn267His)	rs1371733624	0.00003
NM_006254.4(PRKCD):c.1060G>A (p.Val354Ile)	rs782601434	0.00002
NM_006254.4(PRKCD):c.1491G>T (p.Glu497Asp)	rs781785325	0.00002
NM_006254.4(PRKCD):c.1511G>A (p.Arg504Gln)	rs781836069	0.00002
NM_006254.4(PRKCD):c.604G>A (p.Asp202Asn)	rs149165175	0.00002
NM_006254.4(PRKCD):c.647G>A (p.Arg216Gln)	rs782428011	0.00002
NM_006254.4(PRKCD):c.889-9C>T	rs782612523	0.00002
NM_006254.4(PRKCD):c.1036A>G (p.Ile346Val)	rs1434557148	0.00001
NM_006254.4(PRKCD):c.1051T>G (p.Phe351Val)	rs782444193	0.00001
NM_006254.4(PRKCD):c.1123T>G (p.Phe375Val)	rs1003630344	0.00001
NM_006254.4(PRKCD):c.1184T>C (p.Met395Thr)	rs1010140622	0.00001
NM_006254.4(PRKCD):c.1231A>G (p.Thr411Ala)	rs1553669078	0.00001
NM_006254.4(PRKCD):c.1376G>A (p.Cys459Tyr)	rs1553669478	0.00001
NM_006254.4(PRKCD):c.140A>G (p.Lys47Arg)	rs1553666756	0.00001
NM_006254.4(PRKCD):c.1448G>A (p.Arg483Gln)	rs879255393	0.00001
NM_006254.4(PRKCD):c.1501G>T (p.Gly501Trp)	rs782726901	0.00001
NM_006254.4(PRKCD):c.1672G>A (p.Glu558Lys)	rs1575544853	0.00001
NM_006254.4(PRKCD):c.1726A>G (p.Lys576Glu)	rs782371398	0.00001
NM_006254.4(PRKCD):c.1727A>G (p.Lys576Arg)	rs782006621	0.00001
NM_006254.4(PRKCD):c.1744C>T (p.Leu582Phe)	rs781964037	0.00001
NM_006254.4(PRKCD):c.1840C>T (p.Arg614Trp)	rs606231297	0.00001
NM_006254.4(PRKCD):c.1844G>T (p.Arg615Met)	rs74838104	0.00001
NM_006254.4(PRKCD):c.195G>C (p.Glu65Asp)	rs1196790794	0.00001
NM_006254.4(PRKCD):c.202G>A (p.Val68Ile)	rs781950537	0.00001
NM_006254.4(PRKCD):c.22G>A (p.Ala8Thr)	rs368029897	0.00001
NM_006254.4(PRKCD):c.256G>A (p.Val86Met)	rs782298081	0.00001
NM_006254.4(PRKCD):c.268G>A (p.Val90Met)	rs1015113720	0.00001
NM_006254.4(PRKCD):c.297T>A (p.Asn99Lys)	rs561142814	0.00001
NM_006254.4(PRKCD):c.377-10T>C	rs782061483	0.00001
NM_006254.4(PRKCD):c.394C>T (p.Arg132Cys)	rs375221270	0.00001
NM_006254.4(PRKCD):c.531C>G (p.Asp177Glu)	rs1240610213	0.00001
NM_006254.4(PRKCD):c.549C>A (p.Asn183Lys)	rs1378624159	0.00001
NM_006254.4(PRKCD):c.580G>A (p.Ala194Thr)	rs782475090	0.00001
NM_006254.4(PRKCD):c.584C>T (p.Ala195Val)	rs977894332	0.00001
NM_006254.4(PRKCD):c.5C>T (p.Ala2Val)	rs781958692	0.00001
NM_006254.4(PRKCD):c.616G>A (p.Gly206Ser)	rs957946153	0.00001
NM_006254.4(PRKCD):c.631A>T (p.Thr211Ser)	rs1252661978	0.00001
NM_006254.4(PRKCD):c.635C>T (p.Ala212Val)	rs782237403	0.00001
NM_006254.4(PRKCD):c.64G>A (p.Glu22Lys)	rs1553666417	0.00001
NM_006254.4(PRKCD):c.652A>G (p.Thr218Ala)	rs1311722771	0.00001
NM_006254.4(PRKCD):c.742G>A (p.Gly248Ser)	rs144320413	0.00001
NM_006254.4(PRKCD):c.793G>A (p.Gly265Ser)	rs373245386	0.00001
NM_006254.4(PRKCD):c.869C>T (p.Ala290Val)	rs1186631774	0.00001
NM_006254.4(PRKCD):c.884C>T (p.Thr295Ile)	rs782223934	0.00001
NM_006254.4(PRKCD):c.890G>A (p.Arg297Lys)	rs782243565	0.00001
NM_006254.4(PRKCD):c.925C>G (p.Pro309Ala)	rs1703647874	0.00001
NM_006254.4(PRKCD):c.928G>A (p.Val310Ile)	rs773144753	0.00001
NM_006254.4(PRKCD):c.991A>G (p.Ser331Gly)	rs140359417	0.00001
NM_006254.4(PRKCD):c.1003G>A (p.Gly335Ser)	rs564822118
NM_006254.4(PRKCD):c.1025G>T (p.Ser342Ile)
NM_006254.4(PRKCD):c.1034A>T (p.Asn345Ile)
NM_006254.4(PRKCD):c.1040A>G (p.Asn347Ser)	rs1553668944
NM_006254.4(PRKCD):c.1041C>A (p.Asn347Lys)
NM_006254.4(PRKCD):c.1059G>C (p.Lys353Asn)
NM_006254.4(PRKCD):c.1060G>C (p.Val354Leu)	rs782601434
NM_006254.4(PRKCD):c.1081G>A (p.Gly361Arg)	rs369078144
NM_006254.4(PRKCD):c.1083G>T (p.Gly361=)
NM_006254.4(PRKCD):c.1102C>A (p.Leu368Met)
NM_006254.4(PRKCD):c.1102C>G (p.Leu368Val)
NM_006254.4(PRKCD):c.1118A>G (p.Glu373Gly)
NM_006254.4(PRKCD):c.1165G>A (p.Asp389Asn)
NM_006254.4(PRKCD):c.1180A>G (p.Thr394Ala)
NM_006254.4(PRKCD):c.1196G>C (p.Arg399Pro)
NM_006254.4(PRKCD):c.119G>A (p.Arg40His)
NM_006254.4(PRKCD):c.1211C>G (p.Ala404Gly)	rs782150167
NM_006254.4(PRKCD):c.1213G>T (p.Ala405Ser)
NM_006254.4(PRKCD):c.1240A>C (p.Ile414Leu)
NM_006254.4(PRKCD):c.1260+3G>T
NM_006254.4(PRKCD):c.1292A>G (p.Asn431Ser)
NM_006254.4(PRKCD):c.1294G>A (p.Gly432Arg)	rs1190070838
NM_006254.4(PRKCD):c.1306A>T (p.Met436Leu)	rs1439886101
NM_006254.4(PRKCD):c.1329C>T (p.Gly443=)	rs1018675596
NM_006254.4(PRKCD):c.1330C>T (p.Arg444Cys)
NM_006254.4(PRKCD):c.1331G>A (p.Arg444His)
NM_006254.4(PRKCD):c.1345C>T (p.Arg449Cys)	rs1575542392
NM_006254.4(PRKCD):c.1396A>G (p.Ser466Gly)
NM_006254.4(PRKCD):c.139AAG[1] (p.Lys48del)	rs2107256592
NM_006254.4(PRKCD):c.140A>C (p.Lys47Thr)	rs1553666756
NM_006254.4(PRKCD):c.1415+4C>T
NM_006254.4(PRKCD):c.1415+5G>A
NM_006254.4(PRKCD):c.141G>C (p.Lys47Asn)
NM_006254.4(PRKCD):c.1433A>G (p.Asn478Ser)
NM_006254.4(PRKCD):c.1439T>C (p.Leu480Pro)	rs1703806197
NM_006254.4(PRKCD):c.1450G>A (p.Asp484Asn)	rs1703807403
NM_006254.4(PRKCD):c.1469C>T (p.Ala490Val)
NM_006254.4(PRKCD):c.1501G>A (p.Gly501Arg)
NM_006254.4(PRKCD):c.1511G>T (p.Arg504Leu)
NM_006254.4(PRKCD):c.151A>G (p.Met51Val)
NM_006254.4(PRKCD):c.1637C>A (p.Ser546Tyr)
NM_006254.4(PRKCD):c.1637C>T (p.Ser546Phe)	rs1703824527
NM_006254.4(PRKCD):c.1652A>G (p.Asp551Gly)	rs1703825504
NM_006254.4(PRKCD):c.1702C>T (p.Pro568Ser)	rs1703828073
NM_006254.4(PRKCD):c.1707C>G (p.Arg569=)	rs1575544912
NM_006254.4(PRKCD):c.170C>T (p.Ser57Leu)	rs913175157
NM_006254.4(PRKCD):c.1722G>T (p.Glu574Asp)	rs2107286422
NM_006254.4(PRKCD):c.1729G>A (p.Asp577Asn)
NM_006254.4(PRKCD):c.1743+10CTGGG[4]	rs1192292366
NM_006254.4(PRKCD):c.1763C>G (p.Thr588Ser)	rs1703859591
NM_006254.4(PRKCD):c.1781_1782delinsTG (p.Thr594Met)	rs1575545467
NM_006254.4(PRKCD):c.1784G>A (p.Gly595Glu)	rs1352945164
NM_006254.4(PRKCD):c.1797C>G (p.Ile599Met)
NM_006254.4(PRKCD):c.1801C>G (p.Pro601Ala)	rs1703861977
NM_006254.4(PRKCD):c.1805T>C (p.Phe602Ser)
NM_006254.4(PRKCD):c.1822T>C (p.Trp608Arg)	rs1703863535
NM_006254.4(PRKCD):c.1831C>A (p.Leu611Met)
NM_006254.4(PRKCD):c.1847T>G (p.Leu616Trp)	rs2107288493
NM_006254.4(PRKCD):c.1871T>C (p.Val624Ala)	rs782223641
NM_006254.4(PRKCD):c.1872+1G>A	rs782367516
NM_006254.4(PRKCD):c.187A>G (p.Ile63Val)
NM_006254.4(PRKCD):c.214G>A (p.Val72Met)	rs151061939
NM_006254.4(PRKCD):c.250G>A (p.Val84Met)
NM_006254.4(PRKCD):c.250G>T (p.Val84Leu)	rs1327842167
NM_006254.4(PRKCD):c.266C>T (p.Ser89Leu)
NM_006254.4(PRKCD):c.280C>T (p.Arg94Cys)	rs963574725
NM_006254.4(PRKCD):c.287A>G (p.Lys96Arg)
NM_006254.4(PRKCD):c.305C>T (p.Ala102Val)	rs2107257453
NM_006254.4(PRKCD):c.30C>A (p.Asn10Lys)
NM_006254.4(PRKCD):c.315G>A (p.Trp105Ter)	rs2107257487
NM_006254.4(PRKCD):c.377-7T>A	rs372103939
NM_006254.4(PRKCD):c.389C>T (p.Ser130Phe)
NM_006254.4(PRKCD):c.405C>G (p.Asp135Glu)	rs200462015
NM_006254.4(PRKCD):c.417C>G (p.Phe139Leu)	rs56208295
NM_006254.4(PRKCD):c.421A>G (p.Thr141Ala)	rs1703439359
NM_006254.4(PRKCD):c.422C>T (p.Thr141Met)
NM_006254.4(PRKCD):c.433C>T (p.Arg145Cys)	rs2107262808
NM_006254.4(PRKCD):c.442A>G (p.Ile148Val)	rs1559624784
NM_006254.4(PRKCD):c.446A>G (p.Lys149Arg)	rs74793932
NM_006254.4(PRKCD):c.44G>A (p.Gly15Asp)	rs369358922
NM_006254.4(PRKCD):c.458T>C (p.Ile153Thr)	rs370103982
NM_006254.4(PRKCD):c.488C>T (p.Ala163Val)
NM_006254.4(PRKCD):c.544C>T (p.Leu182Phe)	rs1553667592
NM_006254.4(PRKCD):c.563A>G (p.Lys188Arg)
NM_006254.4(PRKCD):c.56C>T (p.Ala19Val)	rs2107253193
NM_006254.4(PRKCD):c.572-6T>C	rs2107267620
NM_006254.4(PRKCD):c.578A>G (p.Asn193Ser)	rs2107267626
NM_006254.4(PRKCD):c.581C>T (p.Ala194Val)	rs1553668112
NM_006254.4(PRKCD):c.610A>T (p.Ile204Phe)	rs1575537929
NM_006254.4(PRKCD):c.646C>T (p.Arg216Trp)	rs782269447
NM_006254.4(PRKCD):c.657+6C>G	rs1397485856
NM_006254.4(PRKCD):c.671G>A (p.Arg224His)	rs1553668239
NM_006254.4(PRKCD):c.680T>C (p.Ile227Thr)
NM_006254.4(PRKCD):c.703G>A (p.Val235Ile)	rs782573482
NM_006254.4(PRKCD):c.743G>A (p.Gly248Asp)	rs1703547897
NM_006254.4(PRKCD):c.744C>T (p.Gly248=)	rs147545646
NM_006254.4(PRKCD):c.778A>C (p.Lys260Gln)
NM_006254.4(PRKCD):c.787+3G>A
NM_006254.4(PRKCD):c.788-3C>T
NM_006254.4(PRKCD):c.818G>A (p.Arg273Gln)
NM_006254.4(PRKCD):c.820G>A (p.Glu274Lys)	rs1553668639
NM_006254.4(PRKCD):c.826G>T (p.Val276Leu)	rs1553668642
NM_006254.4(PRKCD):c.88G>A (p.Val30Met)	rs1703300399
NM_006254.4(PRKCD):c.892G>A (p.Ala298Thr)	rs2107275432
NM_006254.4(PRKCD):c.896C>T (p.Ser299Phe)	rs1703646229
NM_006254.4(PRKCD):c.902G>T (p.Arg301Ile)	rs2107275476
NM_006254.4(PRKCD):c.932G>A (p.Gly311Glu)	rs2107275603
NM_006254.4(PRKCD):c.940C>G (p.Gln314Glu)	rs1553668823
NM_006254.4(PRKCD):c.998C>A (p.Thr333Asn)	rs1703664468

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.