List of variants reported as uncertain significance for central nervous system cancer by Myriad Genetics, Inc.

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 35

Download table as spreadsheet

HGVS	dbSNP	gnomAD frequency
NM_004168.4(SDHA):c.17G>A (p.Gly6Asp)	rs187964306	0.00596
NM_004168.4(SDHA):c.146A>G (p.Asp49Gly)	rs80207011	0.00261
NM_003000.3(SDHB):c.32G>A (p.Arg11His)	rs111430410	0.00185
NM_004168.4(SDHA):c.136A>G (p.Lys46Glu)	rs144599870	0.00145
NM_004168.4(SDHA):c.1919A>G (p.Glu640Gly)	rs372480044	0.00058
NM_004168.4(SDHA):c.704T>C (p.Ile235Thr)	rs144513891	0.00015
NM_004168.4(SDHA):c.1055G>A (p.Arg352Gln)	rs199844384	0.00009
NM_004168.4(SDHA):c.1591G>A (p.Val531Met)	rs371056571	0.00009
NM_004168.4(SDHA):c.1661G>A (p.Arg554Gln)	rs376391115	0.00009
NM_003000.3(SDHB):c.112C>T (p.Arg38Cys)	rs202119350	0.00006
NM_004168.4(SDHA):c.-5C>T	rs572126995	0.00006
NM_004168.4(SDHA):c.1064+5G>A	rs200021115	0.00006
NM_004168.4(SDHA):c.287C>T (p.Thr96Ile)	rs377620054	0.00006
NM_004168.4(SDHA):c.841A>G (p.Thr281Ala)	rs772325115	0.00005
NM_003000.3(SDHB):c.709C>T (p.Pro237Ser)	rs186768244	0.00004
NM_004168.4(SDHA):c.1724C>T (p.Ala575Val)	rs750327309	0.00004
NM_004168.4(SDHA):c.1930G>A (p.Val644Met)	rs3211483	0.00004
NM_004168.4(SDHA):c.739A>G (p.Ile247Val)	rs571292356	0.00004
NM_004168.4(SDHA):c.970G>A (p.Glu324Lys)	rs147014102	0.00004
NM_003000.3(SDHB):c.352G>A (p.Asp118Asn)	rs200021702	0.00002
NM_004168.4(SDHA):c.109G>A (p.Val37Ile)	rs758426529	0.00002
NM_004168.4(SDHA):c.1423T>C (p.Cys475Arg)	rs781747137	0.00002
NM_004168.4(SDHA):c.1652C>T (p.Thr551Met)	rs181238392	0.00002
NM_004168.4(SDHA):c.826G>A (p.Gly276Ser)	rs751008647	0.00002
NM_004168.4(SDHA):c.1196C>T (p.Pro399Leu)	rs878854625	0.00001
NM_004168.4(SDHA):c.1414G>A (p.Glu472Lys)	rs143798161	0.00001
NM_004168.4(SDHA):c.818C>T (p.Thr273Ile)	rs587781720	0.00001
NM_004168.4(SDHA):c.914G>A (p.Cys305Tyr)	rs878854638	0.00001
NM_004168.4(SDHA):c.92G>A (p.Arg31Gln)	rs752532780	0.00001
NM_003000.3(SDHB):c.79C>G (p.Arg27Gly)	rs74315369
NM_004168.4(SDHA):c.1006G>T (p.Asp336Tyr)	rs1553999038
NM_004168.4(SDHA):c.1273G>A (p.Val425Met)	rs201822097
NM_004168.4(SDHA):c.480T>G (p.Phe160Leu)	rs1060503711
NM_004168.4(SDHA):c.955A>G (p.Ile319Val)	rs377509915
NM_004168.4(SDHA):c.996_998delinsCAC (p.Val333Thr)	rs1057517540

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.