ClinVar Miner

List of variants in gene TP53 studied for prostate disorder

Included ClinVar conditions (29):
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:
Total variants: 191
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HGVS dbSNP gnomAD frequency
NM_000546.6(TP53):c.743G>A (p.Arg248Gln) rs11540652 0.00002
NM_000546.6(TP53):c.375G>A (p.Thr125=) rs55863639 0.00001
NM_000546.6(TP53):c.523C>T (p.Arg175Cys) rs138729528 0.00001
NM_000546.6(TP53):c.578A>C (p.His193Pro) rs786201838 0.00001
NM_000546.6(TP53):c.659A>G (p.Tyr220Cys) rs121912666 0.00001
NM_000546.6(TP53):c.716A>C (p.Asn239Thr) rs1057519999 0.00001
NM_000546.6(TP53):c.733G>A (p.Gly245Ser) rs28934575 0.00001
NM_000546.6(TP53):c.817C>T (p.Arg273Cys) rs121913343 0.00001
NM_000546.6(TP53):c.844C>T (p.Arg282Trp) rs28934574 0.00001
NM_000546.6(TP53):c.376-11T>C
NM_000546.6(TP53):c.376-11del
NM_000546.6(TP53):c.376-12del
NM_000546.6(TP53):c.376-12dup
NM_000546.6(TP53):c.376-13C>T rs2073407612
NM_000546.6(TP53):c.376-2A>C rs786202799
NM_000546.6(TP53):c.376-2del
NM_000546.6(TP53):c.376-36dup
NM_000546.6(TP53):c.376-3del
NM_000546.6(TP53):c.376-3delinsAG
NM_000546.6(TP53):c.376-48T>A
NM_000546.6(TP53):c.376-4A>C
NM_000546.6(TP53):c.376-4_376-3delinsTA
NM_000546.6(TP53):c.376-6C>G
NM_000546.6(TP53):c.376-6_376-5insG
NM_000546.6(TP53):c.376-6del
NM_000546.6(TP53):c.376-8del
NM_000546.6(TP53):c.376-8dup
NM_000546.6(TP53):c.376-9T>C
NM_000546.6(TP53):c.376_377delinsCT (p.Tyr126Leu)
NM_000546.6(TP53):c.376delinsAG (p.Tyr126fs)
NM_000546.6(TP53):c.376delinsGG (p.Tyr126fs)
NM_000546.6(TP53):c.377dup (p.Tyr126Ter)
NM_000546.6(TP53):c.378C>A (p.Tyr126Ter) rs1567554500
NM_000546.6(TP53):c.379dup (p.Ser127fs)
NM_000546.6(TP53):c.382C>T (p.Pro128Ser)
NM_000546.6(TP53):c.383del (p.Pro128fs) rs1597371666
NM_000546.6(TP53):c.383dup (p.Ala129fs)
NM_000546.6(TP53):c.386_387insA (p.Leu130fs)
NM_000546.6(TP53):c.387C>T (p.Ala129=)
NM_000546.6(TP53):c.388_390delinsGAT (p.Leu130Asp)
NM_000546.6(TP53):c.388del (p.Leu130fs) rs2151033977
NM_000546.6(TP53):c.388dup (p.Leu130fs)
NM_000546.6(TP53):c.390C>G (p.Leu130=)
NM_000546.6(TP53):c.392del (p.Asn131fs)
NM_000546.6(TP53):c.393del (p.Asn131fs) rs1567554408
NM_000546.6(TP53):c.395del (p.Lys132fs)
NM_000546.6(TP53):c.396_397insT (p.Met133fs)
NM_000546.6(TP53):c.398T>G (p.Met133Arg)
NM_000546.6(TP53):c.401_402delinsCTG (p.Phe134fs)
NM_000546.6(TP53):c.403T>A (p.Cys135Ser) rs1057519975
NM_000546.6(TP53):c.403T>C (p.Cys135Arg) rs1057519975
NM_000546.6(TP53):c.403T>G (p.Cys135Gly) rs1057519975
NM_000546.6(TP53):c.404G>A (p.Cys135Tyr) rs587781991
NM_000546.6(TP53):c.404G>T (p.Cys135Phe) rs587781991
NM_000546.6(TP53):c.405C>G (p.Cys135Trp) rs1057519976
NM_000546.6(TP53):c.409dup (p.Leu137fs)
NM_000546.6(TP53):c.413C>G (p.Ala138Gly) rs750600586
NM_000546.6(TP53):c.413_414insG (p.Lys139fs)
NM_000546.6(TP53):c.413delinsTG (p.Ala138fs)
NM_000546.6(TP53):c.415_416delinsG (p.Lys139fs)
NM_000546.6(TP53):c.417_418insT (p.Thr140fs)
NM_000546.6(TP53):c.421T>A (p.Cys141Ser) rs1057519978
NM_000546.6(TP53):c.421T>C (p.Cys141Arg) rs1057519978
NM_000546.6(TP53):c.421T>G (p.Cys141Gly) rs1057519978
NM_000546.6(TP53):c.421del (p.Cys141fs)
NM_000546.6(TP53):c.421dup (p.Cys141fs)
NM_000546.6(TP53):c.422G>A (p.Cys141Tyr) rs587781288
NM_000546.6(TP53):c.422G>T (p.Cys141Phe) rs587781288
NM_000546.6(TP53):c.422_423insT (p.Val143fs)
NM_000546.6(TP53):c.422dup (p.Cys141fs) rs2073394466
NM_000546.6(TP53):c.423C>G (p.Cys141Trp) rs1057519977
NM_000546.6(TP53):c.424_425del (p.Pro142fs)
NM_000546.6(TP53):c.427G>C (p.Val143Leu)
NM_000546.6(TP53):c.427_428insC (p.Val143fs)
NM_000546.6(TP53):c.428T>A (p.Val143Glu)
NM_000546.6(TP53):c.428del (p.Val143fs)
NM_000546.6(TP53):c.428dup (p.Gln144fs)
NM_000546.6(TP53):c.431A>G (p.Gln144Arg)
NM_000546.6(TP53):c.431del (p.Gln144fs)
NM_000546.6(TP53):c.432_433delinsCA (p.Gln144_Leu145delinsHisMet)
NM_000546.6(TP53):c.432del (p.Gln144fs)
NM_000546.6(TP53):c.433del (p.Leu145fs)
NM_000546.6(TP53):c.435_436delinsAAG (p.Trp146fs)
NM_000546.6(TP53):c.441T>G (p.Val147=)
NM_000546.6(TP53):c.443A>T (p.Asp148Val)
NM_000546.6(TP53):c.453C>A (p.Pro151=)
NM_000546.6(TP53):c.454C>A (p.Pro152Thr)
NM_000546.6(TP53):c.457C>G (p.Pro153Ala)
NM_000546.6(TP53):c.457_458insATGTCGCCACGCGGTCCGAC (p.Pro153fs)
NM_000546.6(TP53):c.460_462delinsAT (p.Gly154fs)
NM_000546.6(TP53):c.461_462delinsAT (p.Gly154Asp)
NM_000546.6(TP53):c.461_462delinsCAT (p.Gly154fs)
NM_000546.6(TP53):c.461_463delinsCAT (p.Gly154_Thr155delinsAlaSer)
NM_000546.6(TP53):c.461delinsAT (p.Gly154fs)
NM_000546.6(TP53):c.463del (p.Thr155fs)
NM_000546.6(TP53):c.476C>A (p.Ala159Asp) rs1555526131
NM_000546.6(TP53):c.481G>A (p.Ala161Thr) rs193920817
NM_000546.6(TP53):c.490A>C (p.Lys164Gln)
NM_000546.6(TP53):c.491del (p.Lys164fs)
NM_000546.6(TP53):c.492_493delinsTT (p.Lys164_Gln165delinsAsnTer)
NM_000546.6(TP53):c.493delinsAA (p.Gln165fs)
NM_000546.6(TP53):c.495_499delinsCCCTA (p.Gln165_Gln167delinsHisProLys)
NM_000546.6(TP53):c.496T>G (p.Ser166Ala)
NM_000546.6(TP53):c.496_497insG (p.Ser166fs)
NM_000546.6(TP53):c.496_497insGC (p.Ser166fs)
NM_000546.6(TP53):c.498del (p.Gln167fs)
NM_000546.6(TP53):c.499_500del (p.Gln167fs)
NM_000546.6(TP53):c.502C>A (p.His168Asn)
NM_000546.6(TP53):c.503dup (p.His168fs)
NM_000546.6(TP53):c.511_512insC (p.Glu171fs)
NM_000546.6(TP53):c.516del (p.Val172_Val173insTer)
NM_000546.6(TP53):c.522del (p.Arg174fs)
NM_000546.6(TP53):c.522dup (p.Arg175fs)
NM_000546.6(TP53):c.523C>G (p.Arg175Gly) rs138729528
NM_000546.6(TP53):c.526T>A (p.Cys176Ser) rs967461896
NM_000546.6(TP53):c.526T>C (p.Cys176Arg) rs967461896
NM_000546.6(TP53):c.526T>G (p.Cys176Gly) rs967461896
NM_000546.6(TP53):c.527G>A (p.Cys176Tyr) rs786202962
NM_000546.6(TP53):c.527G>T (p.Cys176Phe) rs786202962
NM_000546.6(TP53):c.528C>G (p.Cys176Trp) rs1057519980
NM_000546.6(TP53):c.531C>A (p.Pro177=)
NM_000546.6(TP53):c.531CCA[1] (p.His179del)
NM_000546.6(TP53):c.532dup (p.His178fs)
NM_000546.6(TP53):c.533dup (p.His178fs)
NM_000546.6(TP53):c.539dup (p.Arg181fs)
NM_000546.6(TP53):c.545del (p.Cys182fs) rs1567552584
NM_000546.6(TP53):c.546del (p.Ser183fs)
NM_000546.6(TP53):c.548_549insT (p.Asp184fs)
NM_000546.6(TP53):c.548dup (p.Asp184fs)
NM_000546.6(TP53):c.550G>C (p.Asp184His)
NM_000546.6(TP53):c.550_551insC (p.Asp184fs)
NM_000546.6(TP53):c.550del (p.Asp184fs)
NM_000546.6(TP53):c.550dup (p.Asp184fs)
NM_000546.6(TP53):c.554del (p.Ser185fs)
NM_000546.6(TP53):c.554dup (p.Ser185fs)
NM_000546.6(TP53):c.555dup (p.Asp186fs)
NM_000546.6(TP53):c.559+11G>T
NM_000546.6(TP53):c.559+35G>A
NM_000546.6(TP53):c.559+5del
NM_000546.6(TP53):c.577C>A (p.His193Asn) rs876658468
NM_000546.6(TP53):c.577C>G (p.His193Asp) rs876658468
NM_000546.6(TP53):c.577C>T (p.His193Tyr) rs876658468
NM_000546.6(TP53):c.578A>G (p.His193Arg) rs786201838
NM_000546.6(TP53):c.578A>T (p.His193Leu) rs786201838
NM_000546.6(TP53):c.637C>G (p.Arg213Gly) rs397516436
NM_000546.6(TP53):c.638G>A (p.Arg213Gln) rs587778720
NM_000546.6(TP53):c.638G>C (p.Arg213Pro) rs587778720
NM_000546.6(TP53):c.638G>T (p.Arg213Leu) rs587778720
NM_000546.6(TP53):c.658T>A (p.Tyr220Asn) rs530941076
NM_000546.6(TP53):c.658T>C (p.Tyr220His) rs530941076
NM_000546.6(TP53):c.658T>G (p.Tyr220Asp) rs530941076
NM_000546.6(TP53):c.659A>C (p.Tyr220Ser) rs121912666
NM_000546.6(TP53):c.700T>A (p.Tyr234Asn) rs864622237
NM_000546.6(TP53):c.700T>C (p.Tyr234His) rs864622237
NM_000546.6(TP53):c.700T>G (p.Tyr234Asp) rs864622237
NM_000546.6(TP53):c.701A>C (p.Tyr234Ser) rs587780073
NM_000546.6(TP53):c.701A>G (p.Tyr234Cys) rs587780073
NM_000546.6(TP53):c.706T>A (p.Tyr236Asn) rs587782289
NM_000546.6(TP53):c.706T>G (p.Tyr236Asp) rs587782289
NM_000546.6(TP53):c.707A>G (p.Tyr236Cys) rs730882026
NM_000546.6(TP53):c.714T>G (p.Cys238Trp) rs193920789
NM_000546.6(TP53):c.715A>G (p.Asn239Asp) rs876660807
NM_000546.6(TP53):c.716A>G (p.Asn239Ser) rs1057519999
NM_000546.6(TP53):c.733G>C (p.Gly245Arg) rs28934575
NM_000546.6(TP53):c.733G>T (p.Gly245Cys) rs28934575
NM_000546.6(TP53):c.734G>A (p.Gly245Asp) rs121912656
NM_000546.6(TP53):c.734G>C (p.Gly245Ala) rs121912656
NM_000546.6(TP53):c.734G>T (p.Gly245Val) rs121912656
NM_000546.6(TP53):c.742C>G (p.Arg248Gly) rs121912651
NM_000546.6(TP53):c.742C>T (p.Arg248Trp) rs121912651
NM_000546.6(TP53):c.743G>C (p.Arg248Pro) rs11540652
NM_000546.6(TP53):c.743G>T (p.Arg248Leu) rs11540652
NM_000546.6(TP53):c.745A>G (p.Arg249Gly) rs587782082
NM_000546.6(TP53):c.745A>T (p.Arg249Trp) rs587782082
NM_000546.6(TP53):c.746G>A (p.Arg249Lys) rs587782329
NM_000546.6(TP53):c.746G>C (p.Arg249Thr) rs587782329
NM_000546.6(TP53):c.746G>T (p.Arg249Met) rs587782329
NM_000546.6(TP53):c.797G>A (p.Gly266Glu) rs193920774
NM_000546.6(TP53):c.817C>A (p.Arg273Ser) rs121913343
NM_000546.6(TP53):c.818G>A (p.Arg273His) rs28934576
NM_000546.6(TP53):c.818G>C (p.Arg273Pro) rs28934576
NM_000546.6(TP53):c.818G>T (p.Arg273Leu) rs28934576
NM_000546.6(TP53):c.820G>C (p.Val274Leu) rs1057520005
NM_000546.6(TP53):c.820G>T (p.Val274Phe) rs1057520005
NM_000546.6(TP53):c.821T>A (p.Val274Asp) rs1057520006
NM_000546.6(TP53):c.821T>C (p.Val274Ala) rs1057520006
NM_000546.6(TP53):c.821T>G (p.Val274Gly) rs1057520006
NM_000546.6(TP53):c.839G>T (p.Arg280Ile) rs121912660
NM_000546.6(TP53):c.844C>G (p.Arg282Gly) rs28934574
NM_000546.6(TP53):c.845G>A (p.Arg282Gln) rs730882008
NM_000546.6(TP53):c.845G>C (p.Arg282Pro) rs730882008

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