ClinVar Miner

List of variants studied for adrenal cortex neoplasm by OMIM

Included ClinVar conditions (11):

Adenoid cystic carcinoma
Adrenal cortex carcinoma
Adrenocortical adenoma
Adrenocortical carcinoma, hereditary
Adrenocortical carcinoma, hereditary; Familial cancer of breast; Glioma susceptibility 1; Bone osteosarcoma; Li-Fraumeni syndrome 1; Nasopharyngeal carcinoma; Carcinoma of pancreas; Choroid plexus papilloma; Basal cell carcinoma, susceptibility to, 7; Hepatocellular carcinoma; Colorectal cancer; Bone marrow failure syndrome 5
Adrenocortical carcinoma, hereditary; Familial cancer of breast; Glioma susceptibility 1; Bone osteosarcoma; Li-Fraumeni syndrome 1; Nasopharyngeal carcinoma; Carcinoma of pancreas; Choroid plexus papilloma; Carcinoma of colon; Basal cell carcinoma, susceptibility to, 7; Hepatocellular carcinoma
Adrenocortical carcinoma, hereditary; Glioma susceptibility 1; Li-Fraumeni syndrome 1; Choroid plexus papilloma; Basal cell carcinoma, susceptibility to, 7; Colorectal cancer; Bone marrow failure syndrome 5
Aldosterone-producing adrenal cortex adenoma
Epilepsy, idiopathic generalized, susceptibility to, 11; Familial hyperaldosteronism type II; Leukoencephalopathy with mild cerebellar ataxia and white matter edema
Familial hyperaldosteronism type II
Gastrointestinal carcinoma; Adrenal cortex carcinoma

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
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Total variants: 7

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HGVS	dbSNP	gnomAD frequency
NM_004366.6(CLCN2):c.515G>A (p.Arg172Gln)	rs1293789661	0.00001
CLCN2, LYS362DEL
NM_001370259.2(MEN1):c.1654A>T (p.Thr552Ser)	rs121913035
NM_004366.6(CLCN2):c.2593A>C (p.Ser865Arg)	rs1553853557
NM_004366.6(CLCN2):c.65T>A (p.Met22Lys)	rs758379595
NM_004366.6(CLCN2):c.71G>A (p.Gly24Asp)	rs1085307938
NM_004366.6(CLCN2):c.76T>A (p.Tyr26Asn)	rs1553857113

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