List of variants in gene LYST reported as benign for leukopenia

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 94

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HGVS	dbSNP	gnomAD frequency
NM_000081.4(LYST):c.1251A>G (p.Gln417=)	rs1063128	0.41864
NM_000081.4(LYST):c.1683A>G (p.Leu561=)	rs3820553	0.41844
NM_000081.4(LYST):c.4956A>G (p.Leu1652=)	rs6696123	0.41826
NM_000081.4(LYST):c.5373G>A (p.Lys1791=)	rs2273584	0.41769
NM_000081.4(LYST):c.153A>C (p.Gly51=)	rs11464	0.13219
NM_000081.4(LYST):c.2355T>C (p.Leu785=)	rs3768066	0.10928
NM_000081.4(LYST):c.4392C>T (p.Asn1464=)	rs11583387	0.09239
NM_000081.4(LYST):c.2316C>T (p.Asp772=)	rs16832868	0.05899
NM_000081.4(LYST):c.5847G>C (p.Gln1949His)	rs6665568	0.05891
NM_000081.4(LYST):c.6630A>G (p.Glu2210=)	rs34466404	0.05877
NM_000081.4(LYST):c.574T>G (p.Leu192Val)	rs7524261	0.04386
NM_000081.4(LYST):c.8411G>A (p.Gly2804Asp)	rs35333195	0.04044
NM_000081.4(LYST):c.3989A>C (p.Asp1330Ala)	rs74641549	0.04030
NM_000081.4(LYST):c.3050G>A (p.Ser1017Asn)	rs10465613	0.03661
NM_000081.4(LYST):c.5923-19G>T	rs141197189	0.03063
NM_000081.4(LYST):c.7857T>C (p.His2619=)	rs34160788	0.02966
NM_000081.4(LYST):c.6900G>A (p.Leu2300=)	rs10926586	0.02954
NM_000081.4(LYST):c.7137A>C (p.Leu2379=)	rs61738992	0.02884
NM_000081.4(LYST):c.7793T>A (p.Phe2598Tyr)	rs34642241	0.02388
NM_000081.4(LYST):c.9C>T (p.Thr3=)	rs33998267	0.01172
NM_000081.4(LYST):c.5945C>T (p.Thr1982Ile)	rs146591126	0.00669
NM_000081.4(LYST):c.10941-7C>A	rs72761794	0.00614
NM_000081.4(LYST):c.7059+7G>A	rs111764031	0.00582
NM_000081.4(LYST):c.6812A>G (p.Asp2271Gly)	rs112601869	0.00580
NM_000081.4(LYST):c.8898T>C (p.Tyr2966=)	rs144475533	0.00560
NM_000081.4(LYST):c.5518T>G (p.Ser1840Ala)	rs115330112	0.00485
NM_000081.4(LYST):c.10800+4G>T	rs41308172	0.00441
NM_000081.4(LYST):c.6482A>C (p.Glu2161Ala)	rs147756847	0.00416
NM_000081.4(LYST):c.1686G>C (p.Gln562His)	rs77091385	0.00394
NM_000081.4(LYST):c.4863-19T>C	rs150288597	0.00393
NM_000081.4(LYST):c.5291G>C (p.Gly1764Ala)	rs35413645	0.00350
NM_000081.4(LYST):c.6292G>A (p.Ala2098Thr)	rs146091043	0.00315
NM_000081.4(LYST):c.3359G>T (p.Ser1120Ile)	rs143223086	0.00302
NM_000081.4(LYST):c.5223T>C (p.Leu1741=)	rs7530527	0.00277
NM_000081.4(LYST):c.2363+4T>C	rs201398337	0.00252
NM_000081.4(LYST):c.8487C>T (p.Ile2829=)	rs144597913	0.00126
NM_000081.4(LYST):c.4548C>T (p.Ser1516=)	rs116551057	0.00108
NM_000081.4(LYST):c.6588A>G (p.Gly2196=)	rs34423788	0.00093
NM_000081.4(LYST):c.2769A>C (p.Ser923=)	rs112739986	0.00086
NM_000081.4(LYST):c.8368A>C (p.Lys2790Gln)	rs138506576	0.00061
NM_000081.4(LYST):c.9198C>T (p.Ser3066=)	rs543359133	0.00039
NM_000081.4(LYST):c.1655T>C (p.Val552Ala)	rs199617821	0.00038
NM_000081.4(LYST):c.4863-4G>A	rs201382097	0.00032
NM_000081.4(LYST):c.6782G>A (p.Arg2261His)	rs147791378	0.00031
NM_000081.4(LYST):c.368A>G (p.His123Arg)	rs3768067	0.00027
NM_000081.4(LYST):c.2700A>G (p.Leu900=)	rs111463684	0.00017
NM_000081.4(LYST):c.1494A>G (p.Arg498=)	rs201412615	0.00013
NM_000081.4(LYST):c.2150A>G (p.Asn717Ser)	rs201255245	0.00013
NM_000081.4(LYST):c.2517T>C (p.Ile839=)	rs78172154	0.00012
NM_000081.4(LYST):c.6078C>T (p.Tyr2026=)	rs80338660	0.00006
NM_000081.4(LYST):c.2908A>C (p.Ile970Leu)	rs539146732	0.00001
NM_000081.4(LYST):c.6216A>G (p.Val2072=)	rs371248013	0.00001
NM_000081.4(LYST):c.*1275T>C
NM_000081.4(LYST):c.*1499G>T
NM_000081.4(LYST):c.*1723A>G
NM_000081.4(LYST):c.*446T>C
NM_000081.4(LYST):c.*685G>T
NM_000081.4(LYST):c.*725G>A
NM_000081.4(LYST):c.10374+20A>G
NM_000081.4(LYST):c.10565-20del
NM_000081.4(LYST):c.10940+20A>G
NM_000081.4(LYST):c.10941-8dup
NM_000081.4(LYST):c.11196-10del
NM_000081.4(LYST):c.11196-10dup
NM_000081.4(LYST):c.11268-17dup	rs36014994
NM_000081.4(LYST):c.11268-5del	rs36014994
NM_000081.4(LYST):c.11268-6_11268-5del	rs36014994
NM_000081.4(LYST):c.2363+17G>A
NM_000081.4(LYST):c.2364-16dup
NM_000081.4(LYST):c.3436C>T (p.Leu1146Phe)
NM_000081.4(LYST):c.3940-17dup
NM_000081.4(LYST):c.4007-20dup
NM_000081.4(LYST):c.4688+19C>A
NM_000081.4(LYST):c.4863-11T>G
NM_000081.4(LYST):c.5023+14G>A
NM_000081.4(LYST):c.5024-12del
NM_000081.4(LYST):c.5461-13_5461-12dup	rs557545474
NM_000081.4(LYST):c.5461-3del	rs557545474
NM_000081.4(LYST):c.5461-3dup	rs557545474
NM_000081.4(LYST):c.5923-11del
NM_000081.4(LYST):c.5923-11dup
NM_000081.4(LYST):c.5923-4dup
NM_000081.4(LYST):c.6122-13del	rs201404906
NM_000081.4(LYST):c.6122-13dup
NM_000081.4(LYST):c.6253+18G>A
NM_000081.4(LYST):c.6552G>A (p.Gln2184=)
NM_000081.4(LYST):c.7229+50CTTTT[7]	rs71174459
NM_000081.4(LYST):c.7562G>C (p.Arg2521Thr)
NM_000081.4(LYST):c.7973-11del
NM_000081.4(LYST):c.8359-19del
NM_000081.4(LYST):c.8359-5dup
NM_000081.4(LYST):c.8948-12del
NM_000081.4(LYST):c.9162+11G>A
NM_000081.4(LYST):c.9316-19del

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