List of variants in gene MC4R reported as uncertain significance for overnutrition

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 46

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HGVS	dbSNP	gnomAD frequency
NM_005912.3(MC4R):c.307G>A (p.Val103Ile)	rs2229616	0.01533
NM_005912.3(MC4R):c.751A>C (p.Ile251Leu)	rs52820871	0.00774
NM_005912.3(MC4R):c.-176A>G	rs78877161	0.00473
NM_005912.3(MC4R):c.606C>A (p.Phe202Leu)	rs138281308	0.00302
NM_005912.3(MC4R):c.335C>T (p.Thr112Met)	rs13447329	0.00065
NM_005912.3(MC4R):c.677T>C (p.Ile226Thr)	rs193922686	0.00037
NM_005912.3(MC4R):c.523G>A (p.Ala175Thr)	rs121913563	0.00031
NM_005912.3(MC4R):c.-386G>A	rs756482194	0.00021
NM_005912.3(MC4R):c.-60C>G	rs763156013	0.00015
NM_005912.3(MC4R):c.757G>A (p.Val253Ile)	rs187152753	0.00014
NM_005912.2(MC4R):c.110A>T (p.Asp37Val)	rs13447325	0.00013
NM_005912.3(MC4R):c.806T>A (p.Ile269Asn)	rs79783591	0.00011
NM_005912.3(MC4R):c.972C>T (p.Gly324=)	rs150448918	0.00011
NM_005912.3(MC4R):c.-220G>A	rs772697287	0.00008
NM_005912.3(MC4R):c.380C>T (p.Ser127Leu)	rs13447331	0.00008
NM_005912.3(MC4R):c.405A>C (p.Ala135=)	rs140773238	0.00008
NM_005912.3(MC4R):c.-295A>G	rs926966481	0.00006
NM_005912.3(MC4R):c.21T>C (p.Arg7=)	rs760074702	0.00005
NM_005912.3(MC4R):c.913C>T (p.Arg305Trp)	rs549442687	0.00005
NM_005912.3(MC4R):c.534G>A (p.Thr178=)	rs146056286	0.00004
NM_005912.3(MC4R):c.-121G>A	rs541962206	0.00003
NM_005912.3(MC4R):c.776C>T (p.Ala259Val)	rs762825773	0.00003
NM_005912.3(MC4R):c.15C>T (p.Thr5=)	rs199862517	0.00002
NM_005912.3(MC4R):c.-263A>G	rs1915374953	0.00001
NM_005912.3(MC4R):c.-375G>T	rs886054080	0.00001
NM_005912.3(MC4R):c.161T>C (p.Leu54Pro)	rs376439188	0.00001
NM_005912.3(MC4R):c.373A>G (p.Ile125Val)	rs1598932263	0.00001
NM_005912.3(MC4R):c.645G>A (p.Met215Ile)	rs768687497	0.00001
NM_005912.3(MC4R):c.821A>G (p.Asn274Ser)	rs121913561	0.00001
NM_005912.3(MC4R):c.929G>A (p.Arg310Lys)	rs1429906794	0.00001
NM_005912.3(MC4R):c.-161C>T	rs886054079
NM_005912.3(MC4R):c.-18T>C	rs886054077
NM_005912.3(MC4R):c.-359C>A	rs982798124
NM_005912.3(MC4R):c.-360G>A	rs530787706
NM_005912.3(MC4R):c.-59G>A	rs750662653
NM_005912.3(MC4R):c.-64G>A	rs1485034384
NM_005912.3(MC4R):c.-66C>T	rs886054078
NM_005912.3(MC4R):c.201G>A (p.Val67=)	rs886054076
NM_005912.3(MC4R):c.283G>A (p.Val95Ile)
NM_005912.3(MC4R):c.549G>C (p.Leu183Phe)	rs2143966570
NM_005912.3(MC4R):c.63_64del (p.Tyr21_Arg22delinsTer)	rs770293321
NM_005912.3(MC4R):c.655G>T (p.Ala219Ser)	rs1915344558
NM_005912.3(MC4R):c.815C>G (p.Pro272Arg)	rs1915338291
NM_005912.3(MC4R):c.836G>A (p.Cys279Tyr)	rs1915337291
NM_005912.3(MC4R):c.914G>A (p.Arg305Gln)	rs775382722
NM_005912.3(MC4R):c.949A>T (p.Ile317Phe)	rs778685158

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