ClinVar Miner

Variants studied for digestive system disease

Included ClinVar conditions (649):
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign affects association protective risk factor other not provided total
6856 2951 20907 6885 2232 2 15 2 80 1029 569 39487

Gene and significance breakdown #

Total genes and gene combinations: 688
Download table as spreadsheet
Gene or gene combination pathogenic likely pathogenic uncertain significance likely benign benign affects association protective risk factor other not provided total
APC 509 93 2217 482 104 0 0 0 1 930 2 4223
MSH6 477 105 1645 523 87 0 0 0 0 0 2 2667
POLE 2 7 1789 593 71 0 0 0 1 0 0 2426
MSH2 696 149 1224 326 78 0 0 0 0 0 4 2320
MLH1 691 198 858 271 103 0 0 0 0 0 1 1947
PMS2 232 77 903 254 64 0 0 0 0 0 2 1441
POLD1 1 2 937 409 56 0 0 0 3 0 0 1385
CFTR 443 173 358 75 36 0 0 0 0 0 374 1205
CDH1 108 44 724 294 47 0 0 0 0 0 1 1146
ALMS1 78 122 636 233 67 0 0 0 0 0 2 1108
PDGFRA 9 7 559 221 36 0 0 0 0 0 1 813
STK11 78 27 407 242 22 0 0 0 0 0 1 734
KIT 14 45 436 194 23 0 0 0 0 0 0 699
MUTYH 87 67 437 137 11 0 0 0 0 0 1 688
POLG 88 49 253 181 60 0 0 0 0 0 2 576
SMAD4 131 20 259 158 16 0 0 0 0 0 0 568
BMPR1A 55 13 320 108 17 0 0 0 0 0 0 499
COL5A1 48 11 238 99 51 0 0 0 0 0 4 442
FBXL4 27 33 320 1 7 0 0 0 0 0 0 382
SDHB 63 14 205 36 7 0 0 0 0 0 1 325
ABCC8 66 118 109 40 11 0 0 0 0 0 1 317
HNF1B 140 63 41 21 10 0 0 0 0 0 0 264
COL5A2 9 6 160 46 37 0 0 0 0 0 3 257
LRBA 12 2 172 19 40 0 0 0 0 0 0 241
TP53 12 208 6 0 0 0 0 0 0 0 0 221
COL1A2 67 34 67 24 19 0 0 0 0 0 0 208
INSR 40 0 61 68 37 0 0 0 0 0 0 204
GCK 44 100 26 26 5 0 0 0 0 0 0 196
JAG1 49 6 78 45 26 0 0 0 0 0 0 193
NOD2 5 0 106 69 25 0 0 0 5 0 0 188
BBS10 43 65 64 10 7 0 0 0 0 0 0 169
SDHC 10 7 123 26 2 0 0 0 0 0 0 168
EPCAM 24 2 91 44 18 0 0 0 0 0 0 167
PHOX2B 6 2 98 48 11 0 0 0 2 0 0 165
APOB 21 0 101 37 0 0 0 0 0 0 0 159
FECH 17 3 55 46 26 0 0 0 0 0 0 145
GLIS3 4 1 91 28 17 0 0 0 0 0 0 140
CFTR, LOC111674472 58 21 42 3 3 0 0 0 0 0 44 138
CYP27A1 61 30 57 7 9 0 0 0 0 0 0 138
BBS2 29 36 65 21 10 0 0 0 0 0 0 136
CUBN 9 39 65 4 19 0 0 0 0 0 2 132
HNF4A 12 15 76 28 2 0 0 0 0 0 2 131
KCNJ11 40 22 55 17 6 0 0 0 0 0 1 131
SEC63 7 0 50 49 27 0 0 0 0 0 0 131
F5 0 0 86 43 0 0 0 0 0 0 0 129
​intergenic 22 1 7 0 0 0 3 0 0 94 0 127
BBS12 22 27 57 20 22 0 0 0 0 0 0 122
COL5A1, LOC101448202 11 5 65 25 14 0 0 0 0 0 0 120
CBR4, PALLD 0 0 77 33 13 0 0 0 0 0 0 118
PALLD 0 0 51 42 22 0 0 0 1 0 0 114
BBS9 24 3 49 27 25 0 0 0 0 0 0 112
SLC29A3 18 2 59 18 19 0 0 0 0 0 0 105
CEP290 12 2 75 7 4 0 0 0 0 0 0 100
HNF1A 30 27 23 12 8 0 0 0 1 0 6 100
SI 8 3 70 13 6 0 0 0 0 0 0 97
SMARCAL1 16 3 61 15 14 0 0 0 0 0 0 97
BBS1, ZDHHC24 25 23 46 5 8 0 0 0 0 0 0 96
ASTN2, TRIM32 4 1 80 9 3 0 0 0 0 0 0 95
NCF2 16 3 50 7 12 0 0 0 0 0 14 90
SLC26A3 8 48 25 8 2 0 0 0 0 0 0 89
TK2 33 1 46 8 4 0 0 0 0 0 0 88
ALDOB 20 29 32 10 2 0 0 0 0 0 1 85
PRSS1, TRB 17 8 45 10 10 0 0 0 0 0 0 85
IL10RA 4 0 53 18 20 0 0 0 0 0 0 84
MLH3 4 1 55 24 0 0 0 0 0 0 0 83
MTTP 12 3 43 23 12 0 0 0 0 0 0 83
WNT10A 13 3 50 23 5 0 0 0 0 0 0 83
AGPAT2 27 0 42 11 3 0 0 0 0 0 0 81
BBS4 23 6 29 10 17 0 0 0 0 0 0 81
RHBDF2 2 0 27 37 15 0 0 0 0 0 0 81
DCAF17 9 1 47 10 15 0 0 0 0 0 0 80
GYS2 14 3 51 7 11 0 0 0 0 0 0 79
MKS1 5 20 47 7 1 0 0 0 0 0 0 77
KLF11 2 0 49 20 8 0 0 0 0 0 0 76
PCSK9 0 0 45 30 0 0 0 0 0 0 0 75
RRM2B 10 1 21 21 22 0 0 0 0 0 0 75
SLC5A1 3 0 51 18 3 0 0 0 0 0 0 75
BRCA2 24 2 44 2 1 0 0 0 1 0 0 74
SARM1, SLC46A1 4 0 54 7 9 0 0 0 0 0 0 74
MKKS 17 3 35 10 10 0 0 0 0 0 0 73
TYMP 48 1 22 0 3 0 0 0 0 0 0 73
CTSC 16 3 47 6 2 0 0 0 0 0 0 72
LCT 3 7 44 9 9 0 0 0 0 0 0 72
HMBS 43 4 15 8 3 0 0 0 0 0 0 71
BLK 4 0 33 27 9 0 0 0 0 0 0 69
CTRC 7 3 44 11 11 0 1 0 1 0 0 69
ABCB11 14 2 36 9 9 0 0 0 0 0 0 68
TRMU 7 3 38 16 4 0 0 0 0 0 1 68
NCF4 4 0 49 11 8 0 0 0 0 0 0 67
TFR2 7 2 40 13 12 0 0 0 0 0 0 66
BSCL2, HNRNPUL2-BSCL2 28 2 16 16 4 0 0 0 0 0 0 65
BBS7 15 4 33 6 10 0 0 0 0 0 0 64
RET 14 12 22 4 2 0 0 0 15 0 0 62
STAT1 18 5 23 7 11 0 0 0 0 0 1 62
WDPCP 2 0 47 11 7 0 0 0 0 0 0 62
ALAD 6 0 41 11 3 0 0 0 0 0 0 61
PIK3CA 15 55 2 0 0 0 0 0 0 0 0 60
TWNK 6 5 23 21 5 0 0 0 0 0 0 60
POLR2F, SOX10 19 17 11 10 2 0 0 0 0 0 0 59
AKR1D1 5 0 36 11 6 0 0 0 0 0 0 58
PAX9 19 2 27 11 5 0 0 0 0 0 0 58
SKIV2L 4 2 43 7 3 0 0 0 0 0 0 58
SLC19A2 14 1 36 4 3 0 0 0 0 0 0 58
CYBB 27 9 15 2 7 0 0 0 0 0 0 57
ATP8B1, LOC100505549 3 0 31 12 10 0 0 0 0 0 0 56
PHKA2 25 12 14 1 7 0 0 0 0 0 1 56
ALG6 10 20 21 4 4 0 0 0 0 0 0 55
PAX4 3 0 26 20 10 0 0 0 0 0 0 55
CPOX 1 0 21 21 11 0 0 0 0 0 1 54
MPI 8 20 15 2 8 0 0 0 0 0 1 52
SLC39A4 12 0 27 8 6 0 0 0 0 0 0 52
SP110 1 0 38 8 8 0 0 0 0 0 0 52
WFS1 1 0 36 8 7 0 0 0 0 0 0 52
CFTR, LOC111674475 27 4 10 2 1 0 0 0 0 0 15 51
PRKCSH 7 0 16 23 5 0 0 0 0 0 0 51
BRCA1 21 0 25 1 2 0 0 0 1 0 0 50
IL10RB 2 1 37 5 6 0 0 0 0 0 0 50
SUCLA2 6 0 33 8 4 0 0 0 0 0 0 50
CYBA 16 0 21 6 6 0 0 0 0 0 0 49
PALB2 16 0 24 2 6 0 0 0 4 0 0 49
AAAS 12 3 28 6 1 0 0 0 0 0 0 48
MPV17 28 6 15 0 0 0 0 0 0 0 0 48
SDCCAG8 7 4 30 3 6 0 0 0 0 0 0 48
SPINK1 17 1 19 9 9 0 0 0 2 0 1 48
ABCB4 17 3 22 5 3 0 0 0 0 0 0 47
BBS1 12 22 11 6 3 0 0 0 0 0 1 47
SUCLG1 7 1 32 4 2 0 0 0 0 0 0 46
COL1A1 39 1 4 1 0 0 0 0 0 0 0 45
SCO2, TYMP 29 2 4 4 10 0 0 0 0 0 0 45
ENG 0 0 26 17 0 0 0 0 0 0 0 43
INS, INS-IGF2 20 6 9 1 1 0 0 0 0 0 20 43
INSL6, JAK2 1 0 36 3 3 0 0 0 0 0 0 43
PIK3R1 13 3 15 4 7 0 0 0 0 0 1 43
AMACR, C1QTNF3-AMACR 2 0 27 9 5 0 0 0 0 0 0 41
ATP8B1 12 0 23 4 3 0 0 0 0 0 0 41
CFTR, LOC111674477 7 13 14 6 2 0 0 0 0 0 2 41
HADH 7 1 23 8 3 0 0 0 0 0 0 40
FOXP3 14 8 14 2 1 0 0 0 0 0 0 39
TTC8 4 0 26 6 6 0 0 0 0 0 0 39
DGUOK 13 1 21 3 1 0 0 0 0 0 1 38
AGK 11 1 22 1 2 0 0 0 0 0 0 37
EP300 5 2 15 1 14 0 0 0 0 0 0 37
HFE 11 1 22 4 1 0 0 0 0 0 1 37
PLOD2 4 0 26 4 3 0 0 0 0 0 0 37
PPOX 11 1 21 3 0 0 0 0 0 0 1 37
TBX1 3 0 23 1 9 0 0 0 0 0 0 35
EIF2AK3 6 0 20 3 6 0 0 0 0 0 0 34
SLC40A1 0 0 13 12 9 0 0 0 0 0 0 34
CTNNB1 8 30 0 0 0 0 0 0 0 2 0 33
NEUROD1 3 0 20 9 2 0 0 0 0 0 0 33
MUTYH, TOE1 0 0 21 10 1 0 0 0 0 0 0 32
PMS1 0 0 23 9 0 0 0 0 0 0 0 32
SP110, SP140 6 1 14 2 10 0 0 0 0 0 1 32
AMN 1 23 3 1 3 0 0 0 0 0 2 31
BBS5 12 6 3 2 7 0 0 0 0 0 0 30
LOC110011216, PHOX2B 2 0 8 13 8 0 0 0 0 0 0 30
UROD 15 0 11 4 0 0 0 0 0 0 0 30
CYP7B1 1 0 22 5 0 0 0 0 0 0 0 28
KRAS 23 7 0 0 0 0 0 0 0 0 1 27
ADAM17, IAH1 1 0 21 0 4 0 0 0 0 0 0 26
ITCH 1 0 16 5 4 0 0 0 0 0 0 26
PHKG2 11 1 10 1 3 0 0 0 0 0 0 26
AGK, DENND11 1 2 18 4 0 0 0 0 0 0 0 25
ARL6 8 2 11 3 2 0 0 0 0 0 0 25
EIF2AK3, LOC101928371 2 0 21 0 2 0 0 0 0 0 0 25
FPR1 0 0 14 1 10 0 0 0 0 0 0 25
PTF1A 3 0 11 4 7 0 0 0 0 0 0 25
SOX2, SOX2-OT 20 0 4 1 0 0 0 0 0 0 0 25
BRAF 13 13 0 0 0 0 0 0 0 0 0 24
SLC46A1 13 0 11 1 0 0 0 0 0 0 0 24
GLUD1 10 1 6 0 6 0 0 0 0 0 0 23
PDX1 3 5 6 7 2 0 0 0 6 0 1 23
ALG8 10 1 5 1 5 0 0 0 0 0 0 21
ACTG2 16 3 1 0 0 0 0 0 0 0 0 20
FANCI, POLG 1 0 8 7 6 0 0 0 0 0 0 20
FLT4 0 0 20 0 0 0 0 0 0 0 0 20
CC2D2A 6 2 12 0 0 0 0 0 0 0 0 19
CFTR, LOC113664106 14 2 1 0 0 0 0 0 0 0 7 19
FAM83H 14 0 0 0 2 0 0 0 0 0 3 19
SBDS 12 0 5 1 4 0 0 0 0 0 0 19
UGT1A, UGT1A1, UGT1A10, UGT1A3, UGT1A4, UGT1A5, UGT1A6, UGT1A7, UGT1A8, UGT1A9 4 2 10 1 3 0 0 0 0 0 0 19
ADAM17 1 0 11 4 2 0 0 0 0 0 0 18
C12orf43, HNF1A 2 1 7 4 3 0 0 0 0 0 1 18
CFTR, LOC111674463 2 0 12 4 0 0 0 0 0 0 0 18
CHEK2 1 1 13 3 0 0 0 0 0 0 0 18
EDNRB 6 4 4 1 0 0 0 0 5 0 1 18
FLNA 3 0 15 0 0 0 0 0 0 0 0 18
AXIN2 3 1 11 2 1 0 0 0 0 0 0 17
FGFR2 8 9 1 0 0 0 0 0 0 0 0 17
IL10RA, SMIM35 0 0 14 2 1 0 0 0 0 0 0 17
NOTCH2 12 2 3 0 0 0 0 0 0 0 0 17
RBPJ 0 0 0 0 17 0 0 0 0 0 0 17
TTC37 9 2 6 0 0 0 0 0 0 0 0 17
EPCAM, MIR559, MSH2 14 0 3 0 0 0 0 0 0 0 0 16
GATA6 10 0 4 1 1 0 0 0 0 0 0 16
PPP1R3A 0 0 6 4 6 0 0 0 0 0 0 16
ACTA2 1 0 12 2 0 0 0 0 0 0 0 15
AMELX, ARHGAP6 12 0 0 0 0 0 0 0 0 0 3 15
DCDC2 5 0 5 1 4 0 0 0 0 0 0 15
FBXW7 0 15 0 0 0 0 0 0 0 0 0 15
HRAS, LRRC56 0 14 0 0 0 0 0 0 0 0 1 15
KDR 0 0 15 0 0 0 0 0 0 0 0 15
NRAS 8 15 0 0 0 0 0 0 0 0 0 15
TGFBR2 5 1 10 0 0 0 0 0 0 0 0 15
TJP2 12 2 1 0 0 0 0 0 0 0 0 15
ZIC3 2 0 5 9 0 0 0 0 0 0 0 15
ERBB2 1 14 0 0 0 0 0 0 0 0 0 14
MYO5B 7 2 2 0 3 0 0 0 0 0 0 14
TMEM67 10 4 2 0 0 0 0 0 0 0 0 14
EPCAM, MIR559 8 0 5 0 0 0 0 0 0 0 0 13
IER3IP1 3 0 6 3 1 0 0 0 0 0 0 13
LRP6 6 5 2 0 0 0 0 0 0 0 0 13
NBAS 11 1 1 0 0 0 0 0 0 0 0 13
PLIN1 2 0 3 4 4 0 0 0 0 0 0 13
PTEN 3 6 4 0 0 0 0 0 0 0 0 13
SOS1 7 0 6 0 0 0 0 0 0 0 0 13
DSPP 8 3 1 0 0 0 0 0 0 0 0 12
EDA 7 4 0 0 0 0 0 0 0 0 1 12
EDN3 7 4 1 0 0 0 0 0 3 0 0 12
XRCC4 9 1 2 0 0 0 0 0 0 0 0 12
CEL 2 1 6 2 1 0 0 0 0 0 0 11
COX4I2 1 0 9 1 0 0 0 0 0 0 0 11
EPM2AIP1, MLH1 9 0 1 0 1 0 0 0 0 0 0 11
FGFR3 8 0 3 0 0 0 0 0 0 0 0 11
FLT1 0 0 1 0 0 0 0 0 0 0 10 11
JAK2 0 0 10 0 1 0 0 0 0 0 0 11
MYCN 9 1 0 0 1 0 0 0 0 0 0 11
RPGRIP1L 3 1 7 0 0 0 0 0 0 0 0 11
CAVIN1 8 0 2 0 0 0 0 0 0 0 0 10
HBB, LOC106099062, LOC107133510 9 1 0 0 0 0 0 0 0 0 0 10
MET 0 0 10 0 0 0 0 0 0 0 0 10
RBPJL 0 0 0 0 8 0 0 0 2 0 0 10
TNXB 0 0 10 0 0 0 0 0 0 0 0 10
AMACR, C1QTNF3-AMACR, SLC45A2 0 0 0 6 3 0 0 0 0 0 0 9
FKBP10 8 0 1 0 0 0 0 0 0 0 0 9
HAMP 1 0 4 4 0 0 0 0 0 0 0 9
HFE, LOC108783645 2 1 5 0 2 0 0 0 0 0 1 9
LAMB3 8 1 0 0 0 0 0 0 0 0 0 9
LEPR 0 0 7 1 1 0 0 0 0 0 0 9
LOC106029312, NCF1 8 0 1 0 0 0 0 0 0 0 0 9
RFX6 0 0 4 3 2 0 0 0 0 0 0 9
SAR1B 8 1 1 0 0 0 0 0 0 0 0 9
SLC9A3 6 2 1 0 0 0 0 0 0 0 0 9
ACTA2, FAS 0 0 3 5 0 0 0 0 0 0 0 8
BUB1B 1 0 7 0 0 0 0 0 0 0 0 8
CCDC151, PRKCSH 0 0 3 4 1 0 0 0 0 0 0 8
DCAF17, METTL8 2 0 6 0 0 0 0 0 0 0 0 8
DPAGT1, HMBS 0 0 0 4 4 0 0 0 0 0 0 8
ENG, LOC102723566 0 0 5 3 0 0 0 0 0 0 0 8
FLCN 3 1 4 0 0 0 0 0 0 0 0 8
GANAB 5 3 0 0 0 0 0 0 0 0 0 8
LOC110006317, LOC110006318, STK11 4 0 4 0 0 0 0 0 0 0 0 8
MAP2K1 0 8 0 0 0 0 0 0 0 0 0 8
NELFE, SKIV2L 0 0 7 1 0 0 0 0 0 0 0 8
PKHD1 0 8 0 0 0 0 0 0 0 0 0 8
PPARG 4 0 1 0 0 0 3 0 0 0 0 8
RHOA 0 8 0 0 0 0 0 0 0 0 0 8
SLC25A4 6 1 1 0 0 0 0 0 0 0 0 8
WWOX 1 0 6 1 1 0 0 0 0 0 0 8
ZFP57 7 0 1 0 0 0 0 0 0 0 0 8
ABCC8, KCNJ11 0 0 3 7 2 0 0 0 1 0 0 7
ACP4 7 0 0 0 0 0 0 0 0 0 0 7
AKT2 1 1 0 1 4 0 0 0 0 0 0 7
AKT3, SDCCAG8 0 0 6 0 1 0 0 0 0 0 0 7
APOB, APOB3'MAR 0 0 5 2 0 0 0 0 0 0 0 7
ASIC4, GMPPA 5 0 2 0 0 0 0 0 0 0 0 7
CDKN2A 0 7 0 0 0 0 0 0 0 0 0 7
EGFR 1 3 0 0 0 0 0 0 0 0 3 7
ENAM 6 2 1 0 0 0 0 0 0 0 0 7
G6PD 7 0 0 0 0 0 0 0 0 0 0 7
GUCY1A1 7 0 0 0 0 0 0 0 0 0 0 7
IDH2 0 7 0 0 0 0 0 0 0 0 0 7
INS, INS-IGF2, TH 0 0 0 4 4 0 0 0 0 0 0 7
LOC113687175, TFR2 1 1 4 0 1 0 0 0 0 0 0 7
MMP20 4 1 3 0 0 0 0 0 0 0 0 7
MSX1 6 0 1 0 0 0 0 0 0 0 0 7
ORMDL1, PMS1 0 0 3 4 0 0 0 0 0 0 0 7
SLC2A2 2 0 3 1 1 1 0 0 0 0 0 7
WDR72 5 1 1 0 0 0 0 0 0 0 0 7
AIFM3, ARVCF, C22orf39, CDC45, CLDN5, CLTCL1, COMT, CRKL, DGCR2, DGCR6L, DGCR8, ESS2, FAM230A, GGTLC3, GNB1L, GP1BB, GSC2, HIRA, KLHL22, LZTR1, MED15, MRPL40, P2RX6, PI4KA, PRODH, RANBP1, RIMBP3, RTL10, RTN4R, SCARF2, SEPTIN5, SERPIND1, SLC25A1, SLC7A4, SNAP29, TANGO2, TBX1, THAP7, TMEM191B, TRMT2A, TSSK2, TXNRD2, UFD1, USP41, ZDHHC8, ZNF74 5 1 0 0 0 0 0 0 0 0 0 6
BRF1 4 0 2 0 0 0 0 0 0 0 0 6
C12orf29, CEP290 0 0 5 1 0 0 0 0 0 0 0 6
EIF2B2, MLH3 0 0 0 6 0 0 0 0 0 0 0 6
ERBB3 0 6 0 0 0 0 0 0 0 0 0 6
FAM20A, PRKAR1A 5 1 0 0 0 0 0 0 0 0 0 6
IRS1 2 0 1 2 1 0 0 0 0 0 0 6
KIFBP 1 0 3 0 2 0 0 0 0 0 0 6
LOC106780803, TNXB 0 0 6 0 0 0 0 0 0 0 0 6
LRP5 3 0 2 0 0 0 0 0 0 0 4 6
MC4R 1 0 3 1 1 0 0 0 0 0 0 6
TMPRSS15 5 1 0 0 0 0 0 0 0 0 0 6
ABCC8, LOC110121471 2 0 1 2 0 0 0 0 0 0 0 5
AFG3L2 2 1 2 0 0 0 0 0 0 0 0 5
AIMP2, PMS2 0 0 2 0 3 0 0 0 0 0 0 5
ALAS2 5 0 0 0 0 0 0 0 0 0 0 5
B2M 0 5 0 0 0 0 0 0 0 0 0 5
BBS4, HIGD2B 0 0 2 2 1 0 0 0 0 0 0 5
C12orf60, GUCY2C 5 0 0 0 0 0 0 0 0 0 0 5
CASP10 2 0 3 0 0 0 0 0 0 0 0 5
CD55 5 0 0 0 0 0 0 0 0 0 0 5
CREBBP 0 4 1 0 0 0 0 0 0 0 0 5
DGAT1 1 3 1 0 0 0 0 0 0 0 0 5
FARSB 5 0 0 0 0 0 0 0 0 0 0 5
FBXO11, MSH6 2 0 2 0 1 0 0 0 0 0 0 5
FGFR1 0 5 0 0 0 0 0 0 0 0 0 5
GDNF 1 0 1 0 0 0 0 0 4 0 0 5
HSD3B7 5 0 0 0 0 0 0 0 0 0 0 5
HSPA1L 0 0 0 0 0 0 5 0 0 0 0 5
IDH1 0 5 0 0 0 0 0 0 0 0 0 5
MIR6766, POLG 0 0 1 3 1 0 0 0 0 0 0 5
MSH3 4 0 0 0 0 0 0 0 0 0 1 5
MTOR 0 5 0 0 0 0 0 0 0 0 0 5
NCAPH2, SCO2, TYMP 0 0 0 3 2 0 0 0 0 0 0 5
NFE2L2 0 5 0 0 0 0 0 0 0 0 0 5
NTHL1 2 0 3 0 0 0 0 0 0 0 0 5
ODAPH 5 0 0 0 0 0 0 0 0 0 0 5
PTH1R 4 0 1 0 0 0 0 0 0 0 0 5
RBPJL, SDC4 0 0 0 0 5 0 0 0 0 0 0 5
RIPK1 5 0 0 0 0 0 0 0 0 0 0 5
ABCA7, ARHGAP45, ARID3A, CFD, CNN2, ELANE, GPX4, GRIN3B, KISS1R, MED16, POLR2E, R3HDM4, SBNO2, STK11, TMEM259, WDR18 2 0 2 0 0 0 0 0 0 0 0 4
ALG9 0 0 0 0 4 0 0 0 0 0 0 4
BCL10 4 0 0 0 0 0 0 0 0 0 0 4
C10orf67, PTF1A 0 0 0 0 4 0 0 0 0 0 0 4
CAPN10 0 0 0 0 0 0 0 0 4 0 0 4
CAV1 3 0 1 0 0 0 0 0 0 0 0 4
CD36 0 3 0 1 0 0 0 0 0 0 0 4
CDH1, LOC112486201 2 0 2 0 0 0 0 0 0 0 0 4
CLMP 4 0 0 0 0 0 0 0 0 0 0 4
DCDC2, KAAG1 2 0 1 0 1 0 0 0 0 0 0 4
EFL1 2 0 3 0 0 0 0 0 0 0 0 4
FAM20A 4 0 0 0 0 0 0 0 0 0 0 4
INS, TH 0 0 0 4 0 0 0 0 0 0 0 4
ITGB6 4 0 0 0 0 0 0 0 0 0 0 4
LMNA 1 1 1 1 0 0 0 0 0 0 0 4
LZTFL1 3 0 1 0 0 0 0 0 0 0 0 4
MED12 1 2 1 0 0 0 0 0 0 0 0 4
MGME1 3 0 0 0 0 0 0 0 0 0 1 4
MTRR 0 0 4 0 0 0 0 0 0 0 0 4
MYCN, MYCNOS 3 1 0 0 0 0 0 0 0 0 0 4
MYO5B, SNHG22 0 2 1 0 1 0 0 0 0 0 0 4
NR1H4 4 0 0 0 0 0 0 0 0 0 0 4
PAX9, SLC25A21 0 0 3 1 0 0 0 0 0 0 0 4
PNPLA3 0 0 3 0 0 0 0 0 1 0 0 4
PTPN11 0 4 0 0 0 0 0 0 0 0 0 4
SLC24A4 4 0 0 0 0 0 0 0 0 0 0 4
SOX2 4 0 0 0 0 0 0 0 0 0 0 4
TERT 2 0 2 0 0 0 0 0 0 0 0 4
TGFB1 3 0 0 0 0 0 0 0 1 0 0 4
ACOX2 2 0 1 0 0 0 0 0 0 0 0 3
BUB1 3 0 0 0 0 0 0 0 0 0 0 3
C8orf37 2 0 1 0 0 0 0 0 0 0 0 3
CFTR, LOC113633877 1 0 1 0 1 0 0 0 0 0 0 3
CLDN1 3 0 0 0 0 0 0 0 0 0 0 3
DCC 1 0 2 0 0 0 0 0 0 0 0 3
DLX3 3 0 0 0 0 0 0 0 0 0 0 3
EPCAM, MSH2 2 0 1 0 0 0 0 0 0 0 0 3
EPHX1 2 0 1 0 0 0 0 0 0 0 0 3
FBN1 1 1 1 0 0 0 0 0 0 0 0 3
GNAS 0 3 0 0 0 0 0 0 0 0 0 3
GPR68 3 0 0 0 0 0 0 0 0 0 0 3
IFT74 2 1 0 0 0 0 0 0 0 0 1 3
IL10, IL19 0 0 2 0 1 0 0 0 0 0 0 3
IL2RA 0 0 1 0 0 0 2 0 0 0 0 3
INS 3 0 0 0 0 0 0 0 0 0 0 3
KLK4 3 0 0 0 0 0 0 0 0 0 0 3
LARS1 1 0 2 0 0 0 0 0 0 0 0 3
LOC108281188, LRBA 1 0 2 0 0 0 0 0 0 0 0 3
LOC110006318, STK11 3 0 0 0 0 0 0 0 0 0 0 3
MT-CO1 3 0 0 0 0 0 0 0 0 0 0 3
MYC 0 3 0 0 0 0 0 0 0 0 0 3
MYH11 0 2 1 0 0 0 0 0 0 0 0 3
NEUROG3 3 0 0 0 0 0 0 0 0 0 0 3
PPP2R1A 0 3 0 0 0 0 0 0 0 0 0 3
PRSS1 3 0 0 0 0 0 0 0 0 0 0 3
RAF1 0 2 1 0 0 0 0 0 0 0 0 3
REST 3 3 0 0 0 0 0 0 0 0 0 3
SRP54 3 0 0 0 0 0 0 0 0 0 0 3
TRIP11 3 0 0 0 0 0 0 0 0 0 0 3
TRMT10A 2 0 1 0 0 0 0 0 0 0 0 3
XPO1 0 3 0 0 0 0 0 0 0 0 0 3
ABCG8 0 0 2 0 0 0 0 0 0 0 0 2
ACVR1 0 2 0 0 0 0 0 0 0 0 0 2
ACVR1B 2 0 0 0 0 0 0 0 0 0 0 2
ADIRF, AGAP11, ATAD1, BMPR1A, FAM245A, FAM25A, GLUD1, KLLN, LINC00863, LOC111982877, LOC111982878, MINPP1, MIR4678, MMRN2, NUTM2A, NUTM2D, PAPSS2, PTEN, SHLD2, SNCG 2 0 0 0 0 0 0 0 0 0 0 2
AHNAK 0 0 2 0 0 0 0 0 0 0 0 2
AIFM3, ARVCF, C22orf39, CDC45, CLDN5, CLTCL1, COMT, CRKL, DGCR2, DGCR6, DGCR6L, DGCR8, ESS2, FAM230A, GGT2, GGTLC3, GNB1L, GP1BB, GSC2, HIC2, HIRA, KLHL22, LZTR1, MED15, MRPL40, P2RX6, PI4KA, PRODH, RANBP1, RIMBP3, RIMBP3B, RTL10, RTN4R, SCARF2, SEPTIN5, SERPIND1, SLC25A1, SLC7A4, SNAP29, TANGO2, TBX1, THAP7, TMEM191B, TRMT2A, TSSK2, TXNRD2, UFD1, USP18, USP41, ZDHHC8, ZNF74 2 0 0 0 0 0 0 0 0 0 0 2
AIFM3, ARVCF, C22orf39, CDC45, CLDN5, CLTCL1, COMT, CRKL, DGCR2, DGCR6L, DGCR8, ESS2, FAM230A, GGT2, GGTLC3, GNB1L, GP1BB, GSC2, HIC2, HIRA, KLHL22, LZTR1, MED15, MRPL40, P2RX6, PI4KA, PRODH, RANBP1, RIMBP3, RIMBP3B, RTL10, RTN4R, SCARF2, SEPTIN5, SERPIND1, SLC25A1, SLC7A4, SNAP29, TANGO2, TBX1, THAP7, TMEM191B, TRMT2A, TSSK2, TXNRD2, UFD1, USP41, ZDHHC8, ZNF74 2 0 0 0 0 0 0 0 0 0 0 2
AMBN 2 0 0 0 0 0 0 0 0 0 0 2
APOB, LOC106560211 0 0 1 1 0 0 0 0 0 0 0 2
APPL1 2 0 0 0 0 0 0 0 0 0 0 2
ARHGAP11A-SCG5, GREM1, LOC105370757, SCG5 0 0 2 0 0 0 0 0 0 0 0 2
ARHGAP11A-SCG5, GREM1, SCG5 1 0 1 0 0 0 0 0 0 0 0 2
ARID1A 0 0 0 0 0 0 1 0 0 1 0 2
ASCL1 2 0 0 0 0 0 0 0 0 0 0 2
BAAT 1 0 1 0 0 0 0 0 0 0 0 2
BAX 2 0 0 0 0 0 0 0 0 0 0 2
BBIP1 1 0 1 0 0 0 0 0 0 0 0 2
BLVRA 2 0 0 0 0 0 0 0 0 0 0 2
BMP4 0 0 2 0 0 0 0 0 0 0 0 2
BRIP1 1 1 0 0 0 0 0 0 0 0 0 2
BSCL2 2 0 0 0 0 0 0 0 0 0 0 2
C22orf39, CDC45, CLDN5, CLTCL1, DGCR2, ESS2, GP1BB, GSC2, HIRA, MRPL40, PRODH, SEPTIN5, SLC25A1, TBX1, TSSK2, UFD1 2 0 0 0 0 0 0 0 0 0 0 2
CBARP, STK11 0 0 1 1 0 0 0 0 0 0 0 2
CDKAL1 0 0 2 0 0 0 0 0 0 0 0 2
CFTR, LOC113219471 2 0 0 0 0 0 0 0 0 0 0 2
CFTR, LOC113664106, LOC113664107 2 0 0 0 0 0 0 0 0 0 0 2
CLMP, LOC112042785 2 0 0 0 0 0 0 0 0 0 0 2
CNOT9 0 2 0 0 0 0 0 0 0 0 0 2
ECE1 0 2 0 0 0 0 0 0 0 0 0 2
EDAR, RANBP2 1 1 0 0 0 0 0 0 0 0 0 2
ENPP1 0 0 0 0 0 0 0 0 2 0 0 2
FANCB 0 0 2 0 0 0 0 0 0 0 0 2
FOXF1 0 2 0 0 0 0 0 0 0 0 0 2
GALNT12 0 0 1 0 1 0 0 0 0 0 0 2
GLI3 0 1 1 0 0 0 0 0 0 0 0 2
GPD1 2 0 0 0 0 0 0 0 0 0 0 2
GREM2 2 0 0 0 0 0 0 0 0 0 0 2
HJV 2 0 0 0 0 0 0 0 0 0 0 2
IFT27, LOC105373021 2 0 0 0 0 0 0 0 0 0 0 2
IGF2R 2 0 0 0 0 0 0 0 0 0 0 2
LOC108281111, PAX9 0 0 2 0 0 0 0 0 0 0 0 2
LOC110120888, TBX1 2 0 0 0 0 0 0 0 0 0 0 2
LRRFIP2, MLH1 1 0 0 0 1 0 0 0 0 0 0 2
MAP2K2 0 2 0 0 0 0 0 0 0 0 0 2
MATN4, RBPJL 0 0 0 0 2 0 0 0 0 0 0 2
MCC 2 0 0 0 0 0 0 0 0 0 0 2
MCM6 0 0 2 0 0 0 0 0 0 0 0 2
MEN1 2 0 0 0 0 0 0 0 0 0 0 2
MT-CYB 2 0 0 0 0 0 0 0 0 0 0 2
MT-TE 2 0 0 0 0 0 0 0 0 0 0 2
MT-TK 2 0 0 0 0 0 0 0 0 0 0 2
MTHFR 0 0 2 0 0 0 0 0 0 0 1 2
MYLK 2 0 0 0 0 0 0 0 0 0 0 2
NSMCE2 2 0 0 0 0 0 0 0 0 0 0 2
NTF3 0 0 1 1 0 0 0 0 0 0 0 2
OBSL1 0 0 2 0 0 0 0 0 0 0 0 2
OPA1 1 0 1 0 0 0 0 0 0 0 0 2
PDGFRL 2 0 0 0 0 0 0 0 0 0 0 2
PKD1 2 0 0 0 0 0 0 0 0 0 0 2
PLOD1 2 0 0 0 0 0 0 0 0 0 0 2
PNLIP 1 1 0 0 0 0 0 0 0 0 0 2
PNPLA6 2 0 0 0 0 0 0 0 0 0 0 2
PPP1R15B 1 0 1 0 0 0 0 0 0 0 0 2
PTPRJ 2 0 0 0 0 0 0 0 0 0 0 2
PTRH2 2 0 0 0 0 0 0 0 0 0 0 2
RB1 1 1 0 0 0 0 0 0 0 0 0 2
RINT1 2 0 0 0 0 0 0 0 0 0 0 2
RNF43 2 0 0 0 0 0 0 0 0 0 0 2
RXRA 0 2 0 0 0 0 0 0 0 0 0 2
SEMA3D 0 1 2 0 0 0 0 0 0 0 0 2
SEMA4A 0 0 2 0 0 0 0 0 0 0 0 2
SF3B1 0 2 0 0 0 0 0 0 0 0 0 2
SF3B2 0 2 0 0 0 0 0 0 0 0 0 2
SLC16A1 2 0 0 0 0 0 0 0 0 0 0 2
SLC30A8 0 0 0 0 0 0 0 2 0 0 0 2
TCF7L2 0 0 0 0 0 0 0 0 2 0 0 2
U2AF1 0 2 0 0 0 0 0 0 0 0 0 2
WNT10B 2 0 0 0 0 0 0 0 0 0 0 2
XDH 0 0 2 0 0 0 0 0 0 0 0 2
XRCC2 0 0 2 0 0 0 0 0 0 0 0 2
AAAS, C12orf10 1 0 0 0 0 0 0 0 0 0 0 1
AATF, ACACA, C17orf78, DDX52, DHRS11, DUSP14, GGNBP2, HNF1B, LHX1, MRM1, MYO19, PIGW, SYNRG, TADA2A, ZNHIT3 1 0 0 0 0 0 0 0 0 0 0 1
ABCB1 0 0 0 0 0 0 0 0 1 0 0 1
ABCD3 1 0 0 0 0 0 0 0 0 0 0 1
ABCG5, ABCG8 1 0 0 0 0 0 0 0 0 0 0 1
ABCG5, ABCG8, ARHGEF33, ATL2, ATP6V1E2, BCYRN1, C2orf91, CALM2, CAMKMT, CDKL4, COX7A2L, CRIPT, CYP1B1, DHX57, DYNC2LI1, EML4, EPAS1, EPCAM, GALM, GEMIN6, HAAO, HNRNPLL, KCNG3, LRPPRC, MAP4K3, MCFD2, MORN2, MSH2, MTA3, OXER1, PIGF, PKDCC, PLEKHH2, PPM1B, PREPL, PRKCE, RHOQ, RMDN2, SIX2, SIX3, SLC3A1, SLC8A1, SOCS5, SOS1, SOS1-IT1, SRBD1, SRSF7, STPG4, THADA, THUMPD2, TMEM178A, TMEM247, TTC7A, ZFP36L2 1 0 0 0 0 0 0 0 0 0 0 1
ABO, ADAMTS13, ADAMTSL2, AK8, BARHL1, BRD3, C9orf116, C9orf62, CACFD1, CEL, CFAP77, COL5A1, DBH, DDX31, FAM163B, FCN1, FCN2, GBGT1, GFI1B, GLT6D1, GTF3C4, GTF3C5, KCNT1, LCN1, LCN9, MED22, MED27, MRPS2, MYMK, NTNG2, OBP2A, OBP2B, OLFM1, PAEP, POMT1, PPP1R26, RALGDS, RAPGEF1, REXO4, RNU6ATAC, RPL7A, RXRA, SARDH, SETX, SLC2A6, SOHLH1, SPACA9, STKLD1, SURF1, SURF2, SURF4, SURF6, TSC1, TTF1, UCK1, VAV2, WDR5 0 0 1 0 0 0 0 0 0 0 0 1
ABR, BHLHA9, TRARG1, YWHAE 0 0 0 1 0 0 0 0 0 0 0 1
ACADVL 0 0 1 0 0 0 0 0 0 0 0 1
ACTL6A 0 1 0 0 0 0 0 0 0 0 0 1
ADAMTS4, APOA2, ARHGAP30, B4GALT3, CD244, DEDD, F11R, FCER1G, ITLN1, ITLN2, KLHDC9, LOC101928372, LOC112543491, LY9, MIR5187, MPZ, NDUFS2, NECTIN4, NIT1, NR1I3, PCP4L1, PFDN2, PPOX, SDHC, TOMM40L, TSTD1, UFC1, USF1, USP21 0 0 1 0 0 0 0 0 0 0 0 1
ADIRF, AGAP11, ATAD1, BMPR1A, FAM25A, GLUD1, KLLN, MINPP1, MMRN2, NUTM2A, PAPSS2, PTEN, SHLD2, SNCG 1 0 0 0 0 0 0 0 0 0 0 1
AGMAT, CASP9, CELA2A, CELA2B, CTRC, DDI2, DNAJC16, PLEKHM2, RSC1A1, SLC25A34 1 0 0 0 0 0 0 0 0 0 0 1
AGMO 0 0 0 1 0 0 0 0 0 0 0 1
AIFM3, ARVCF, C22orf39, CDC45, CLDN5, CLTCL1, COMT, CRKL, DGCR2, DGCR6, DGCR6L, DGCR8, ESS2, FAM230A, GGTLC3, GNB1L, GP1BB, GSC2, HIRA, KLHL22, LZTR1, MED15, MRPL40, P2RX6, PI4KA, PRODH, RANBP1, RIMBP3, RTL10, RTN4R, SCARF2, SEPTIN5, SERPIND1, SLC25A1, SLC7A4, SNAP29, TANGO2, TBX1, THAP7, TMEM191B, TRMT2A, TSSK2, TXNRD2, UFD1, USP41, ZDHHC8, ZNF74 1 0 0 0 0 0 0 0 0 0 0 1
AKAP9 0 0 0 0 1 0 0 0 0 0 0 1
AKT1 1 1 0 0 0 0 0 0 0 0 0 1
AKT3, CEP170, LINC01347, LOC110120698, MIR4677, PLD5, SDCCAG8 1 0 0 0 0 0 0 0 0 0 0 1
ALPK3, NMB, PDE8A, SEC11A, SLC28A1, WDR73, ZNF592, ZSCAN2 0 0 0 1 0 0 0 0 0 0 0 1
AMN, TRAF3 1 0 0 0 0 0 0 0 0 0 0 1
AMTN 1 0 0 0 0 0 0 0 0 0 0 1
ANKRD54, C22orf23, EIF3L, GALR3, GCAT, H1-0, MICALL1, MIR658, MIR659, MIR6820, POLR2F, SOX10 1 0 0 0 0 0 0 0 0 0 0 1
ANKS1B, UHRF1BP1L 0 0 0 1 0 0 0 0 0 0 0 1
ANO5 1 0 0 0 0 0 0 0 0 0 0 1
AOPEP, FANCC 1 0 0 0 0 0 0 0 0 0 0 1
APC, LOC102467216 0 1 0 0 0 0 0 0 0 0 0 1
APC, LOC112997553, REEP5, SRP19 1 0 0 0 0 0 0 0 0 0 0 1
ARHGAP11A-SCG5, GREM1, LOC100131315, LOC105370757, SCG5 0 0 1 0 0 0 0 0 0 0 0 1
ARHGAP11A-SCG5, GREM1, LOC100131315, SCG5 0 0 1 0 0 0 0 0 0 0 0 1
ARHGAP11A-SCG5, LOC105370757, SCG5 1 0 0 0 0 0 0 0 0 0 0 1
ARID1B 0 0 1 0 0 0 0 0 0 0 0 1
ARL6, CRYBG3 0 1 0 0 0 0 0 0 0 0 0 1
ARVCF, C22orf39, CDC45, CLDN5, CLTCL1, COMT, DGCR2, DGCR6, DGCR6L, DGCR8, ESS2, GNB1L, GP1BB, GSC2, HIRA, MRPL40, PRODH, RANBP1, RTL10, RTN4R, SEPTIN5, SLC25A1, TANGO2, TBX1, TRMT2A, TSSK2, TXNRD2, UFD1, ZDHHC8 1 0 0 0 0 0 0 0 0 0 0 1
ARVCF, C22orf39, CDC45, CLDN5, CLTCL1, COMT, DGCR2, DGCR6L, DGCR8, ESS2, GNB1L, GP1BB, GSC2, HIRA, MRPL40, PRODH, RANBP1, RTL10, RTN4R, SEPTIN5, SLC25A1, TANGO2, TBX1, TRMT2A, TSSK2, TXNRD2, UFD1, ZDHHC8 1 0 0 0 0 0 0 0 0 0 0 1
ARVCF, COMT, GNB1L, GP1BB, LOC110120888, LOC112694764, LOC112694766, MIR4761, RTL10, SEPT5-GP1BB, SEPTIN5, TBX1, TXNRD2 1 0 0 0 0 0 0 0 0 0 0 1
ASCL1, PAH 1 0 0 0 0 0 0 0 0 0 0 1
ATE1, FGFR2, WDR11 0 0 1 0 0 0 0 0 0 0 0 1
ATP2B3 1 0 0 0 0 0 0 0 0 0 0 1
AXIN1 1 0 0 0 0 0 0 0 0 0 0 1
B3GNTL1, METRNL, TBCD 0 0 0 1 0 0 0 0 0 0 0 1
BBS1, DPP3, ZDHHC24 0 1 0 0 0 0 0 0 0 0 0 1
BDNF 0 0 1 0 0 0 0 0 0 0 0 1
BEND2, CHD7 0 0 1 0 0 0 0 0 0 0 0 1
BLK, FAM167A 1 0 0 0 0 0 0 0 0 0 0 1
C10orf55, PLAU 0 0 1 0 0 0 0 0 0 0 0 1
C10orf67, LINC01552, PTF1A 0 0 0 0 1 0 0 0 0 0 0 1
C12orf60, GUCY2C, PLBD1 1 0 0 0 0 0 0 0 0 0 0 1
CASP8 1 0 0 0 0 0 0 0 0 0 0 1
CCDC28B 0 0 1 0 0 0 0 0 0 0 0 1
CCDC74A, MZT2A, TUBA3D 0 0 0 1 0 0 0 0 0 0 0 1
CCR9, LZTFL1 0 0 1 0 0 0 0 0 0 0 0 1
CDH13 0