List of variants in gene combination UGT1A, UGT1A1, UGT1A10, UGT1A3, UGT1A4, UGT1A5, UGT1A6, UGT1A7, UGT1A8, UGT1A9 reported as uncertain significance for digestive system disorder

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 44

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HGVS	dbSNP	gnomAD frequency
NM_001072.4(UGT1A6):c.862-10021T>G	rs4124874	0.56024
NM_000463.3(UGT1A1):c.540A>G (p.Glu180=)	rs148755655	0.00201
NM_000463.3(UGT1A1):c.141C>T (p.Ile47=)	rs34526305	0.00154
NM_000463.3(UGT1A1):c.1122T>C (p.Gly374=)	rs139698110	0.00126
NM_000463.3(UGT1A1):c.326T>C (p.Val109Ala)	rs144217005	0.00098
NM_000463.3(UGT1A1):c.748T>C (p.Ser250Pro)	rs57307513	0.00041
NM_000463.3(UGT1A1):c.674T>G (p.Val225Gly)	rs35003977	0.00034
NM_000463.3(UGT1A1):c.1352C>T (p.Pro451Leu)	rs114982090	0.00018
NM_000463.3(UGT1A1):c.584G>A (p.Arg195Lys)	rs767764203	0.00016
NM_000463.3(UGT1A1):c.294T>C (p.Asn98=)	rs138183896	0.00011
NM_000463.3(UGT1A1):c.1324C>T (p.Arg442Cys)	rs143033456	0.00009
NM_000463.3(UGT1A1):c.189C>T (p.Asp63=)	rs191471887	0.00009
NM_000463.3(UGT1A1):c.*84T>C	rs78684540	0.00007
NM_000463.3(UGT1A1):c.25C>T (p.Arg9Cys)	rs370790922	0.00007
NM_000463.3(UGT1A1):c.*269C>T	rs762669023	0.00006
NM_000463.3(UGT1A1):c.1411G>A (p.Ala471Thr)	rs775532505	0.00006
NM_000463.3(UGT1A1):c.577G>A (p.Val193Met)	rs375974892	0.00006
NM_000463.3(UGT1A1):c.142C>G (p.Gln48Glu)	rs747942373	0.00005
NM_000463.3(UGT1A1):c.477C>T (p.Ile159=)	rs199766420	0.00005
NM_000463.3(UGT1A1):c.*461G>T	rs142810023	0.00003
NM_000463.3(UGT1A1):c.1099C>T (p.Arg367Cys)	rs55750087	0.00003
NM_000463.3(UGT1A1):c.1207C>T (p.Arg403Cys)	rs778766461	0.00003
NM_000463.3(UGT1A1):c.167A>C (p.Glu56Ala)	rs140365717	0.00003
NM_000463.3(UGT1A1):c.*419T>C	rs34942353	0.00002
NM_000463.3(UGT1A1):c.1548A>T (p.Lys516Asn)	rs772037816	0.00002
NM_000463.3(UGT1A1):c.*188T>G	rs200041554	0.00001
NM_000463.3(UGT1A1):c.*201G>A	rs541532523	0.00001
NM_000463.3(UGT1A1):c.*674G>A	rs1473113676	0.00001
NM_000463.3(UGT1A1):c.137C>T (p.Ala46Val)	rs886044683	0.00001
NM_000463.3(UGT1A1):c.1410C>T (p.Gly470=)	rs769720139	0.00001
NM_000463.3(UGT1A1):c.288G>A (p.Gly96=)	rs769310438	0.00001
NM_000463.3(UGT1A1):c.300T>C (p.Phe100=)	rs374655757	0.00001
NM_000463.3(UGT1A1):c.838T>G (p.Cys280Gly)	rs754213125	0.00001
NM_000463.3(UGT1A1):c.*133G>A	rs561946796
NM_000463.3(UGT1A1):c.*301G>A	rs1700551616
NM_000463.3(UGT1A1):c.*585G>T	rs886055800
NM_000463.3(UGT1A1):c.1180T>C (p.Phe394Leu)	rs1699600557
NM_000463.3(UGT1A1):c.1322T>C (p.Met441Thr)	rs202172337
NM_000463.3(UGT1A1):c.1518C>A (p.Thr506=)	rs190427553
NM_000463.3(UGT1A1):c.179T>C (p.Leu60Pro)
NM_000463.3(UGT1A1):c.361G>C (p.Ala121Pro)	rs1697515818
NM_000463.3(UGT1A1):c.386A>G (p.His129Arg)	rs1191873899
NM_000463.3(UGT1A1):c.686C>T (p.Pro229Leu)	rs35350960
NM_000463.3(UGT1A1):c.964A>G (p.Ile322Val)	rs200903749

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