ClinVar Miner

List of variants in gene IRF3 studied for herpes simplex infectious disease

Included ClinVar conditions (7):

Encephalopathy, acute, infection-induced (herpes-specific), susceptibility to, 7
Herpes simplex encephalitis, susceptibility to, 1
Herpes simplex encephalitis, susceptibility to, 3
Herpes simplex encephalitis, susceptibility to, 4
Immunodeficiency 83, susceptibility to viral infections
Primary open angle glaucoma; Herpes simplex encephalitis, susceptibility to, 1; Frontotemporal dementia and/or amyotrophic lateral sclerosis 4; Encephalopathy, acute, infection-induced (herpes-specific), susceptibility to, 8
Susceptibility to HIV infection; Immunodeficiency 83, susceptibility to viral infections

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
		ClinVar version:

Total variants: 3

Download table as spreadsheet

HGVS	dbSNP	gnomAD frequency
NM_001571.6(IRF3):c.432G>C (p.Leu144=)	rs74980832	0.01556
NM_001571.6(IRF3):c.829G>A (p.Ala277Thr)	rs143769046	0.00460
NM_001571.6(IRF3):c.854G>A (p.Arg285Gln)	rs750526659	0.00002

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