ClinVar Miner

Variants studied for acute lymphoblastic leukemia (disease)

Included ClinVar conditions (9):
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign risk factor not provided total
21 12 23 0 0 1 1 58

Gene and significance breakdown #

Total genes and gene combinations: 18
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Gene or gene combination pathogenic likely pathogenic uncertain significance risk factor not provided total
NBN 2 2 20 0 0 24
INSL6, JAK2 4 0 0 0 0 4
PAX5 1 0 2 1 0 4
ABL1 1 2 0 0 0 3
FLT3 3 0 0 0 0 3
JAK1 0 3 0 0 0 3
BAX 2 0 0 0 0 2
ETV6 2 0 0 0 0 2
FGFR1 0 2 0 0 0 2
GNB1 2 0 0 0 0 2
JAK3 0 2 0 0 0 2
ACTB 1 0 0 0 0 1
BCL10 1 0 0 0 0 1
CDH1 0 0 1 0 0 1
CRLF2 1 0 0 0 0 1
IL7R 0 1 0 0 0 1
NT5C2 0 0 0 0 1 1
PMS2 1 0 0 0 0 1

Submitter and significance breakdown #

Total submitters: 12
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Submitter pathogenic likely pathogenic uncertain significance risk factor not provided total
Fulgent Genetics 2 1 18 0 0 21
Database of Curated Mutations (DoCM) 5 10 0 0 1 16
OMIM 9 0 0 1 0 10
Diagnostic Molecular Genetics Laboratory,Memorial Sloan Kettering Cancer Center 2 0 0 0 0 2
Clinical Genomics Lab,St. Jude Children's Research Hospital 1 0 1 0 0 2
Genetic Services Laboratory, University of Chicago 0 1 0 0 0 1
GeneReviews 1 0 0 0 0 1
Genomic Research Center,Shahid Beheshti University of Medical Sciences 0 0 1 0 0 1
HudsonAlpha Institute for Biotechnology 0 0 1 0 0 1
Soonchunhyang University Bucheon Hospital,Soonchunhyang University Medical Center 0 0 1 0 0 1
Center for Genomics, Ann and Robert H. Lurie Children's Hospital of Chicago 0 0 1 0 0 1
Mayo Clinic Genomics Laboratory,Mayo Clinic 1 0 0 0 0 1

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