ClinVar Miner

List of variants reported as uncertain significance for atrial fibrillation by Illumina Laboratory Services, Illumina

Included ClinVar conditions (51):
Minimum submission review status: Collection method:
Minimum conflict level:
ClinVar version:
Total variants: 267
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HGVS dbSNP gnomAD frequency
NM_000891.3(KCNJ2):c.*2753T>C rs1391769255 0.03695
NM_000891.3(KCNJ2):c.*2759T>C rs906331617 0.03578
NM_000891.3(KCNJ2):c.*2754T>C rs9915769 0.02225
NM_002234.4(KCNA5):c.1733G>A (p.Arg578Lys) rs12720445 0.00612
NM_000891.3(KCNJ2):c.*211T>C rs56194813 0.00513
NM_002234.4(KCNA5):c.615G>C (p.Leu205=) rs12720443 0.00441
NM_002234.4(KCNA5):c.570C>T (p.Asn190=) rs12720444 0.00368
NM_000218.3(KCNQ1):c.*717T>G rs189162344 0.00329
NM_000891.3(KCNJ2):c.*79C>T rs55970278 0.00327
NM_002234.4(KCNA5):c.-52G>T rs547432787 0.00322
NM_000891.3(KCNJ2):c.*2262C>T rs575383136 0.00279
NM_000218.3(KCNQ1):c.-5T>C rs532941548 0.00267
NM_000891.3(KCNJ2):c.*3163T>A rs149224363 0.00248
NM_000891.3(KCNJ2):c.*3208A>G rs188533495 0.00233
NM_000891.3(KCNJ2):c.*2893C>T rs137870461 0.00231
NM_000891.3(KCNJ2):c.*2483G>A rs559751598 0.00158
NM_000218.3(KCNQ1):c.*837G>A rs139633955 0.00155
NM_000891.3(KCNJ2):c.*732T>G rs150985434 0.00145
NM_000891.3(KCNJ2):c.*210A>T rs146282466 0.00140
NM_000891.3(KCNJ2):c.-314T>C rs566186294 0.00140
NM_000218.3(KCNQ1):c.459G>A (p.Thr153=) rs148121889 0.00134
NM_000891.3(KCNJ2):c.*766C>T rs186842823 0.00130
NM_002234.4(KCNA5):c.633G>C (p.Glu211Asp) rs35853292 0.00128
NM_002234.4(KCNA5):c.1595C>T (p.Pro532Leu) rs17221812 0.00127
NM_000218.3(KCNQ1):c.*904T>C rs186055804 0.00125
NM_005266.7(GJA5):c.-67G>A rs36214923 0.00108
NM_000218.3(KCNQ1):c.*1025G>C rs181226788 0.00091
NM_181703.4(GJA5):c.*22G>A rs201046055 0.00088
NM_000891.3(KCNJ2):c.*2277C>T rs185701493 0.00071
NM_000891.3(KCNJ2):c.*1794C>A rs55864879 0.00067
NM_005266.7(GJA5):c.-51G>C rs759091909 0.00064
NM_181703.4(GJA5):c.*508G>A rs587741640 0.00052
NM_000218.3(KCNQ1):c.*391G>A rs774059974 0.00048
NM_172201.2(KCNE2):c.-13+5G>A rs786205806 0.00043
NM_000218.3(KCNQ1):c.811C>T (p.Leu271=) rs189991547 0.00041
NM_000218.3(KCNQ1):c.1800G>A (p.Thr600=) rs147091980 0.00037
NM_181703.4(GJA5):c.995G>A (p.Arg332His) rs116551187 0.00037
NM_000891.3(KCNJ2):c.*996C>T rs77958248 0.00035
NM_172201.2(KCNE2):c.*62G>A rs72550218 0.00034
NM_000891.3(KCNJ2):c.*35A>C rs72552029 0.00033
NM_000218.3(KCNQ1):c.-55G>C rs562468879 0.00030
NM_000218.3(KCNQ1):c.1794+11G>A rs186188610 0.00029
NM_000218.3(KCNQ1):c.386+14C>T rs370023636 0.00026
NM_000218.3(KCNQ1):c.1355G>A (p.Arg452Gln) rs145229963 0.00025
NM_181703.4(GJA5):c.13A>G (p.Ser5Gly) rs144069395 0.00025
NM_000891.3(KCNJ2):c.*3536C>T rs529969829 0.00022
NM_000891.3(KCNJ2):c.*3618A>G rs530574251 0.00022
NM_000891.3(KCNJ2):c.-228C>T rs765064661 0.00022
NM_000218.3(KCNQ1):c.1352G>A (p.Arg451Gln) rs199472781 0.00020
NM_002234.4(KCNA5):c.98A>T (p.Glu33Val) rs71584818 0.00020
NM_002234.4(KCNA5):c.898G>A (p.Gly300Ser) rs148708451 0.00019
NM_172201.2(KCNE2):c.153G>T (p.Leu51=) rs143767851 0.00019
NM_172201.2(KCNE2):c.354G>A (p.Gly118=) rs187917779 0.00019
NM_181703.4(GJA5):c.348G>A (p.Glu116=) rs150168016 0.00019
NM_000891.3(KCNJ2):c.*1465A>G rs183514608 0.00018
NM_002234.4(KCNA5):c.251A>C (p.Glu84Ala) rs377036305 0.00018
NM_000891.3(KCNJ2):c.*108G>A rs188588568 0.00017
NM_002234.4(KCNA5):c.1672G>A (p.Gly558Arg) rs201328038 0.00016
NM_002234.4(KCNA5):c.36T>C (p.Gly12=) rs886049572 0.00016
NM_000891.3(KCNJ2):c.*1128dup rs777658732 0.00014
NM_000891.3(KCNJ2):c.*213G>A rs886053326 0.00014
NM_000891.3(KCNJ2):c.*879C>T rs969533203 0.00014
NM_000218.3(KCNQ1):c.1189C>T (p.Arg397Trp) rs199472776 0.00013
NM_000218.3(KCNQ1):c.820A>G (p.Ile274Val) rs199472728 0.00013
NM_000891.3(KCNJ2):c.*2887T>G rs770284843 0.00013
NM_002234.4(KCNA5):c.1329C>T (p.Ile443=) rs147209278 0.00013
NM_002234.4(KCNA5):c.701G>T (p.Arg234Leu) rs371521698 0.00012
NM_000218.3(KCNQ1):c.*266G>A rs113029000 0.00011
NM_000218.3(KCNQ1):c.1476A>G (p.Glu492=) rs370676650 0.00011
NM_000891.3(KCNJ2):c.-349C>A rs370696463 0.00011
NM_005266.7(GJA5):c.-68C>T rs763234536 0.00011
NM_000218.3(KCNQ1):c.*392A>C rs868129989 0.00010
NM_000891.3(KCNJ2):c.*2875_*2876del rs561353262 0.00010
NM_000891.3(KCNJ2):c.*3409A>G rs551384883 0.00010
NM_000891.3(KCNJ2):c.867C>T (p.Asn289=) rs201909993 0.00010
NM_002234.4(KCNA5):c.*50G>A rs368484048 0.00010
NM_002234.4(KCNA5):c.926G>A (p.Gly309Asp) rs369120527 0.00010
NM_005266.7(GJA5):c.-108G>A rs782165709 0.00010
NM_000218.3(KCNQ1):c.1152C>T (p.Ala384=) rs144615901 0.00009
NM_000891.3(KCNJ2):c.-195C>G rs544342049 0.00009
NM_000218.3(KCNQ1):c.387-7C>T rs201682200 0.00008
NM_000891.3(KCNJ2):c.*1815G>A rs552577704 0.00008
NM_002234.4(KCNA5):c.231C>T (p.Pro77=) rs747738816 0.00008
NM_000218.3(KCNQ1):c.*1055C>T rs375155898 0.00007
NM_000891.3(KCNJ2):c.*2616A>G rs542407766 0.00007
NM_000891.3(KCNJ2):c.277G>A (p.Val93Ile) rs147750704 0.00007
NM_181703.4(GJA5):c.*333C>G rs200310520 0.00007
NM_181703.4(GJA5):c.*60C>T rs886045248 0.00007
NM_000218.3(KCNQ1):c.*897G>T rs561861522 0.00006
NM_000218.3(KCNQ1):c.900A>C (p.Ala300=) rs727504769 0.00006
NM_000891.3(KCNJ2):c.*2065A>G rs778894111 0.00006
NM_000891.3(KCNJ2):c.*3353C>T rs886053346 0.00006
NM_172201.2(KCNE2):c.79C>T (p.Arg27Cys) rs74315449 0.00006
NM_000218.3(KCNQ1):c.*581T>C rs765566577 0.00005
NM_000218.3(KCNQ1):c.1903G>A (p.Gly635Arg) rs199473484 0.00005
NM_000218.3(KCNQ1):c.780+12G>A rs200796314 0.00005
NM_000218.3(KCNQ1):c.868G>A (p.Glu290Lys) rs199473464 0.00005
NM_000891.3(KCNJ2):c.*709A>G rs950748341 0.00005
NM_000218.3(KCNQ1):c.*240C>T rs773743391 0.00004
NM_000218.3(KCNQ1):c.*554T>G rs886048172 0.00004
NM_000218.3(KCNQ1):c.*712G>A rs745447199 0.00004
NM_000218.3(KCNQ1):c.*730C>T rs930321240 0.00004
NM_000218.3(KCNQ1):c.-38C>T rs886048160 0.00004
NM_000218.3(KCNQ1):c.41G>T (p.Arg14Leu) rs1424013094 0.00004
NM_000891.3(KCNJ2):c.*1320C>T rs923732685 0.00004
NM_000891.3(KCNJ2):c.*1440A>T rs886053332 0.00004
NM_000891.3(KCNJ2):c.*2508G>A rs913851832 0.00004
NM_000891.3(KCNJ2):c.*2812T>C rs886053344 0.00004
NM_000891.3(KCNJ2):c.-88C>T rs886053322 0.00004
NM_000891.3(KCNJ2):c.119G>A (p.Arg40Gln) rs766143485 0.00004
NM_002234.4(KCNA5):c.1539C>T (p.Pro513=) rs145832242 0.00004
NM_002234.4(KCNA5):c.1789C>T (p.Arg597Trp) rs759691488 0.00004
NM_172201.2(KCNE2):c.*234G>A rs981526333 0.00004
NM_172201.2(KCNE2):c.-85G>A rs41315511 0.00004
NM_181703.4(GJA5):c.1068A>G (p.Leu356=) rs886045250 0.00004
NM_181703.4(GJA5):c.377C>T (p.Pro126Leu) rs782780433 0.00004
NM_000218.3(KCNQ1):c.*171G>A rs886048168 0.00003
NM_000218.3(KCNQ1):c.*66C>T rs994976684 0.00003
NM_000218.3(KCNQ1):c.1375G>A (p.Asp459Asn) rs747704276 0.00003
NM_000218.3(KCNQ1):c.1514+3G>A rs374767819 0.00003
NM_000218.3(KCNQ1):c.1944C>T (p.Val648=) rs201698592 0.00003
NM_000891.3(KCNJ2):c.*122G>A rs886053324 0.00003
NM_000891.3(KCNJ2):c.*124G>A rs886053325 0.00003
NM_000891.3(KCNJ2):c.*2698T>C rs368668294 0.00003
NM_000891.3(KCNJ2):c.*3032A>G rs548485707 0.00003
NM_000891.3(KCNJ2):c.-348G>A rs993406508 0.00003
NM_000891.3(KCNJ2):c.1259C>T (p.Pro420Leu) rs749707062 0.00003
NM_002234.4(KCNA5):c.-210G>C rs1459093560 0.00003
NM_002234.4(KCNA5):c.268C>T (p.Arg90Trp) rs764215137 0.00003
NM_172201.2(KCNE2):c.-121C>T rs188625398 0.00003
NM_000218.3(KCNQ1):c.*290A>G rs765204255 0.00002
NM_000218.3(KCNQ1):c.898G>A (p.Ala300Thr) rs120074187 0.00002
NM_000891.3(KCNJ2):c.*1367T>C rs565257870 0.00002
NM_000891.3(KCNJ2):c.*1702CT[3] rs1555604187 0.00002
NM_000891.3(KCNJ2):c.*2001A>G rs886053336 0.00002
NM_000891.3(KCNJ2):c.531C>T (p.Gly177=) rs544384907 0.00002
NM_172201.2(KCNE2):c.-80C>T rs566735365 0.00002
NM_181703.4(GJA5):c.*520A>T rs886045246 0.00002
NM_181703.4(GJA5):c.342C>G (p.Ala114=) rs886045251 0.00002
NM_000218.3(KCNQ1):c.*295G>A rs1296388392 0.00001
NM_000218.3(KCNQ1):c.*47A>C rs754931159 0.00001
NM_000218.3(KCNQ1):c.*633G>A rs886048173 0.00001
NM_000218.3(KCNQ1):c.*652G>A rs886048174 0.00001
NM_000218.3(KCNQ1):c.*81C>T rs771815387 0.00001
NM_000218.3(KCNQ1):c.1514+9C>T rs770840921 0.00001
NM_000218.3(KCNQ1):c.1556G>A (p.Arg519His) rs199472788 0.00001
NM_000218.3(KCNQ1):c.1794+12C>T rs727505084 0.00001
NM_000218.3(KCNQ1):c.1830C>T (p.Thr610=) rs774101297 0.00001
NM_000218.3(KCNQ1):c.1973C>A (p.Thr658Asn) rs377661455 0.00001
NM_000218.3(KCNQ1):c.514G>A (p.Val172Met) rs199472694 0.00001
NM_000891.3(KCNJ2):c.*1030C>T rs1310873825 0.00001
NM_000891.3(KCNJ2):c.*1361C>A rs1191660760 0.00001
NM_000891.3(KCNJ2):c.*1412G>A rs886053331 0.00001
NM_000891.3(KCNJ2):c.*3025G>A rs536788614 0.00001
NM_000891.3(KCNJ2):c.*3352T>A rs886053345 0.00001
NM_000891.3(KCNJ2):c.*39C>T rs1196218333 0.00001
NM_000891.3(KCNJ2):c.*572G>T rs566129544 0.00001
NM_000891.3(KCNJ2):c.*687A>C rs886053329 0.00001
NM_000891.3(KCNJ2):c.-361G>C rs984704301 0.00001
NM_000891.3(KCNJ2):c.1211C>G (p.Pro404Arg) rs760459401 0.00001
NM_000891.3(KCNJ2):c.1275G>A (p.Ser425=) rs555386610 0.00001
NM_000891.3(KCNJ2):c.22C>T (p.Arg8Cys) rs529080615 0.00001
NM_000891.3(KCNJ2):c.303T>C (p.Cys101=) rs376921497 0.00001
NM_000891.3(KCNJ2):c.845T>G (p.Leu282Trp) rs758092571 0.00001
NM_002234.4(KCNA5):c.*244C>T rs992233743 0.00001
NM_002234.4(KCNA5):c.*558G>T rs1043815479 0.00001
NM_002234.4(KCNA5):c.1210C>T (p.Leu404=) rs886049576 0.00001
NM_002234.4(KCNA5):c.140A>G (p.Lys47Arg) rs886049573 0.00001
NM_002234.4(KCNA5):c.1701G>A (p.Gly567=) rs771735295 0.00001
NM_020297.4(ABCC9):c.4316-14T>G rs886049168 0.00001
NM_172201.2(KCNE2):c.178T>A (p.Phe60Ile) rs16991654 0.00001
NM_172201.2(KCNE2):c.17A>G (p.Asn6Ser) rs776661633 0.00001
NM_181703.4(GJA5):c.*498A>T rs1232691592 0.00001
NM_181703.4(GJA5):c.334G>C (p.Glu112Gln) rs886045252 0.00001
NM_181703.4(GJA5):c.353G>A (p.Arg118Gln) rs782580208 0.00001
NM_181703.4(GJA5):c.938T>C (p.Ile313Thr) rs782224153 0.00001
NM_000218.3(KCNQ1):c.*1088G>C rs886048177
NM_000218.3(KCNQ1):c.*125C>T rs1848376672
NM_000218.3(KCNQ1):c.*160C>A rs886048167
NM_000218.3(KCNQ1):c.*26C>A rs886048166
NM_000218.3(KCNQ1):c.*292C>A rs886048169
NM_000218.3(KCNQ1):c.*398C>T rs886048170
NM_000218.3(KCNQ1):c.*539G>C rs886048171
NM_000218.3(KCNQ1):c.*877C>G rs763163556
NM_000218.3(KCNQ1):c.*887_*889del rs886048175
NM_000218.3(KCNQ1):c.-69G>A rs886048159
NM_000218.3(KCNQ1):c.1251+13C>T rs201364493
NM_000218.3(KCNQ1):c.1343C>T (p.Pro448Leu) rs12720449
NM_000218.3(KCNQ1):c.1394-13A>G rs747187696
NM_000218.3(KCNQ1):c.1394-8C>T rs371488379
NM_000218.3(KCNQ1):c.1590+13C>A rs1846544314
NM_000218.3(KCNQ1):c.1855T>A (p.Leu619Met) rs199472819
NM_000218.3(KCNQ1):c.187C>A (p.Pro63Thr) rs1280717988
NM_000218.3(KCNQ1):c.1895G>A (p.Arg632Lys) rs1848365419
NM_000218.3(KCNQ1):c.1979C>A (p.Pro660His) rs886048165
NM_000218.3(KCNQ1):c.29C>A (p.Ala10Asp) rs886048161
NM_000218.3(KCNQ1):c.387-12C>T rs1445658296
NM_000218.3(KCNQ1):c.534C>T (p.Ala178=) rs1848319199
NM_000218.3(KCNQ1):c.648C>A (p.Gly216=) rs146350010
NM_000218.3(KCNQ1):c.650C>T (p.Ser217Phe) rs886048163
NM_000218.3(KCNQ1):c.66C>T (p.Gly22=) rs886048162
NM_000218.3(KCNQ1):c.684-15C>G rs752087023
NM_000218.3(KCNQ1):c.781-6G>T rs886048164
NM_000218.3(KCNQ1):c.921+12A>G rs1848365236
NM_000891.3(KCNJ2):c.*1226C>G rs749246339
NM_000891.3(KCNJ2):c.*1345G>A rs141156477
NM_000891.3(KCNJ2):c.*1449C>T rs2074403807
NM_000891.3(KCNJ2):c.*1631C>G rs886053333
NM_000891.3(KCNJ2):c.*1646T>C rs2074404964
NM_000891.3(KCNJ2):c.*1702_*1704dup rs1555604193
NM_000891.3(KCNJ2):c.*1702dup rs886053334
NM_000891.3(KCNJ2):c.*1719_*1721dup rs35753731
NM_000891.3(KCNJ2):c.*1720_*1721dup rs35753731
NM_000891.3(KCNJ2):c.*1721dup rs35753731
NM_000891.3(KCNJ2):c.*2270G>T rs545863243
NM_000891.3(KCNJ2):c.*2328T>G rs1233305858
NM_000891.3(KCNJ2):c.*2339G>C rs1273347996
NM_000891.3(KCNJ2):c.*2343C>T rs536283660
NM_000891.3(KCNJ2):c.*2370C>T rs2074409675
NM_000891.3(KCNJ2):c.*2526A>G rs886053337
NM_000891.3(KCNJ2):c.*2663T>C rs886053338
NM_000891.3(KCNJ2):c.*2748T>C rs9915768
NM_000891.3(KCNJ2):c.*2770_*2775del rs35656864
NM_000891.3(KCNJ2):c.*2771_*2775del rs35656864
NM_000891.3(KCNJ2):c.*2772_*2775del rs35656864
NM_000891.3(KCNJ2):c.*2774_*2775del rs35656864
NM_000891.3(KCNJ2):c.*2775dup rs35656864
NM_000891.3(KCNJ2):c.*2776del rs886053343
NM_000891.3(KCNJ2):c.*308C>T rs2074395230
NM_000891.3(KCNJ2):c.*3173C>A rs1467380962
NM_000891.3(KCNJ2):c.*324del rs570173316
NM_000891.3(KCNJ2):c.*3391_*3392dup rs552636156
NM_000891.3(KCNJ2):c.*3463del rs3841509
NM_000891.3(KCNJ2):c.*596T>A rs886053328
NM_000891.3(KCNJ2):c.-162delinsTCAGAGTAGT rs376713253
NM_000891.3(KCNJ2):c.-258C>T rs886053321
NM_000891.3(KCNJ2):c.1254C>G (p.Pro418=) rs748445140
NM_000891.3(KCNJ2):c.341A>G (p.Asp114Gly) rs2074386589
NM_000891.3(KCNJ2):c.344C>T (p.Ala115Val) rs886053323
NM_002234.4(KCNA5):c.*493A>G rs886049577
NM_002234.4(KCNA5):c.*782G>A rs189015926
NM_002234.4(KCNA5):c.*782G>C rs189015926
NM_002234.4(KCNA5):c.-49G>C rs886049571
NM_002234.4(KCNA5):c.-85G>C rs943854010
NM_002234.4(KCNA5):c.186G>C (p.Ser62=) rs760015626
NM_002234.4(KCNA5):c.258A>C (p.Pro86=) rs886049574
NM_002234.4(KCNA5):c.389G>A (p.Arg130His) rs751342646
NM_002234.4(KCNA5):c.435C>A (p.Leu145=) rs1377732998
NM_002234.4(KCNA5):c.602G>A (p.Arg201His) rs765380398
NM_002234.4(KCNA5):c.847C>T (p.Arg283Cys) rs886049575
NM_005266.7(GJA5):c.-125C>T rs1664486266
NM_020297.4(ABCC9):c.1165-4del rs886049172
NM_020297.4(ABCC9):c.1165-6dup rs35857705
NM_020297.4(ABCC9):c.1165-7_1165-6del rs35857705
NM_020297.4(ABCC9):c.2238-16del rs886049170
NM_172201.2(KCNE2):c.*11A>C rs558860396
NM_172201.2(KCNE2):c.*240G>C rs773295544
NM_172201.2(KCNE2):c.*61C>T rs551483595
NM_181703.4(GJA5):c.*1211A>G rs886045244
NM_181703.4(GJA5):c.*1259C>T rs886045243
NM_181703.4(GJA5):c.*364C>T rs886045247
NM_181703.4(GJA5):c.*46T>C rs886045249
NM_181703.4(GJA5):c.*616T>C rs202133825
NM_181703.4(GJA5):c.1057T>G (p.Ser353Ala) rs1663814972
NM_181703.4(GJA5):c.241C>T (p.Gln81Ter) rs1557943827
NM_181703.4(GJA5):c.744C>A (p.Cys248Ter) rs1557942871
NM_181703.4(GJA5):c.956A>T (p.Gln319Leu) rs1663821317

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