List of variants in gene CHEK2 reported as benign for breast carcinoma

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 33

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HGVS	dbSNP	gnomAD frequency
NC_000022.11:g.28741882C>T	rs2236141	0.09783
NM_007194.4(CHEK2):c.252A>G (p.Glu84=)	rs1805129	0.04009
NM_007194.4(CHEK2):c.1542+11T>A	rs17881716	0.01583
NM_007194.4(CHEK2):c.1343T>G (p.Ile448Ser)	rs17886163	0.00555
NM_007194.4(CHEK2):c.593-14C>T	rs145754558	0.00235
NM_007194.4(CHEK2):c.254C>T (p.Pro85Leu)	rs17883862	0.00201
NM_007194.4(CHEK2):c.1407G>A (p.Val469=)	rs17881378	0.00190
NM_007194.4(CHEK2):c.320-5T>A	rs121908700	0.00070
NM_007194.4(CHEK2):c.793-11G>A	rs5997387	0.00054
NM_007194.4(CHEK2):c.538C>T (p.Arg180Cys)	rs77130927	0.00051
NM_007194.4(CHEK2):c.1176G>A (p.Ala392=)	rs142692907	0.00034
NM_007194.4(CHEK2):c.1497G>C (p.Leu499=)	rs587780890	0.00032
NM_007194.4(CHEK2):c.444+19T>C	rs200501745	0.00026
NM_007194.4(CHEK2):c.7C>T (p.Arg3Trp)	rs199708878	0.00013
NM_007194.4(CHEK2):c.1095+19G>A	rs200020484	0.00009
NM_007194.4(CHEK2):c.847-17T>C	rs199780411	0.00006
NM_007194.4(CHEK2):c.15G>A (p.Ser5=)	rs145183886	0.00004
NM_007194.4(CHEK2):c.847-10C>G	rs745745105	0.00004
NM_007194.4(CHEK2):c.1259+17T>C	rs746109434	0.00002
NM_007194.4(CHEK2):c.793-17T>C	rs778511901	0.00002
NM_007194.4(CHEK2):c.1287G>A (p.Glu429=)	rs758102180	0.00001
NM_007194.4(CHEK2):c.1590C>T (p.Ala530=)	rs786201796	0.00001
NM_007194.4(CHEK2):c.1593G>A (p.Glu531=)	rs758555487	0.00001
NM_007194.4(CHEK2):c.573G>C (p.Leu191=)	rs786201267	0.00001
NM_007194.4(CHEK2):c.135G>A (p.Thr45=)	rs745423387
NM_007194.4(CHEK2):c.1543-14dup	rs2145739856
NM_007194.4(CHEK2):c.319+39dup	rs3841692
NM_007194.4(CHEK2):c.474A>G (p.Ala158=)	rs745699485
NM_007194.4(CHEK2):c.592+81del	rs746878232
NM_007194.4(CHEK2):c.84C>A (p.Ser28=)	rs863224415
NM_007194.4(CHEK2):c.908+18del	rs778668907
NM_007194.4(CHEK2):c.908+18dup
NM_007194.4(CHEK2):c.909-28_909-20del	rs1555915597

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