ClinVar Miner

List of variants reported as likely pathogenic for gastric adenocarcinoma by Counsyl

Included ClinVar conditions (9):

Familial cancer of breast; Blepharocheilodontic syndrome 1; Endometrial carcinoma; Hereditary diffuse gastric adenocarcinoma; Familial prostate cancer; Ovarian cancer
Familial cancer of breast; Blepharocheilodontic syndrome 1; Endometrial carcinoma; Hereditary diffuse gastric adenocarcinoma; Ovarian neoplasm; Malignant tumor of prostate
Familial cancer of breast; Blepharocheilodontic syndrome 1; Hereditary diffuse gastric adenocarcinoma; Malignant tumor of prostate
Familial cancer of breast; Hereditary diffuse gastric adenocarcinoma
Familial cancer of breast; Hereditary diffuse gastric adenocarcinoma; Lung carcinoma; Noonan syndrome 3; Linear nevus sebaceous syndrome; Cerebral arteriovenous malformation; Malignant tumor of urinary bladder; Carcinoma of pancreas; Autoimmune lymphoproliferative syndrome type 4; Acute myeloid leukemia; Cardiofaciocutaneous syndrome 2
Gastric adenocarcinoma
Hereditary diffuse gastric adenocarcinoma
Hereditary diffuse gastric adenocarcinoma; CDH1-related diffuse gastric and lobular breast cancer syndrome
Hereditary diffuse gastric adenocarcinoma; Malignant tumor of breast

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Minimum conflict level: Report conflict between different conditions
Show significances as they were submitted (without aggregation into standard terms)
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Total variants: 8

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HGVS	dbSNP	gnomAD frequency
NM_004360.5(CDH1):c.1137G>A (p.Thr379=)	rs587783050
NM_004360.5(CDH1):c.12G>A (p.Trp4Ter)	rs1555509636
NM_004360.5(CDH1):c.1895_1896del (p.His632fs)	rs1060501224
NM_004360.5(CDH1):c.1921C>T (p.Gln641Ter)	rs587782750
NM_004360.5(CDH1):c.1942G>T (p.Glu648Ter)	rs971882211
NM_004360.5(CDH1):c.2296-1G>A	rs1057517542
NM_004360.5(CDH1):c.715G>A (p.Gly239Arg)	rs587780537
NM_004360.5(CDH1):c.720del (p.Asn240fs)	rs1131690819

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