ClinVar Miner

List of variants reported as likely benign for gastric adenocarcinoma by Department of Pathology and Laboratory Medicine, Sinai Health System

Included ClinVar conditions (9):

Familial cancer of breast; Blepharocheilodontic syndrome 1; Endometrial carcinoma; Hereditary diffuse gastric adenocarcinoma; Familial prostate cancer; Ovarian cancer
Familial cancer of breast; Blepharocheilodontic syndrome 1; Endometrial carcinoma; Hereditary diffuse gastric adenocarcinoma; Ovarian neoplasm; Malignant tumor of prostate
Familial cancer of breast; Blepharocheilodontic syndrome 1; Hereditary diffuse gastric adenocarcinoma; Malignant tumor of prostate
Familial cancer of breast; Hereditary diffuse gastric adenocarcinoma
Familial cancer of breast; Hereditary diffuse gastric adenocarcinoma; Lung carcinoma; Noonan syndrome 3; Linear nevus sebaceous syndrome; Cerebral arteriovenous malformation; Malignant tumor of urinary bladder; Carcinoma of pancreas; Autoimmune lymphoproliferative syndrome type 4; Acute myeloid leukemia; Cardiofaciocutaneous syndrome 2
Gastric adenocarcinoma
Hereditary diffuse gastric adenocarcinoma
Hereditary diffuse gastric adenocarcinoma; CDH1-related diffuse gastric and lobular breast cancer syndrome
Hereditary diffuse gastric adenocarcinoma; Malignant tumor of breast

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Minimum conflict level: Report conflict between different conditions
Show significances as they were submitted (without aggregation into standard terms)
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Total variants: 5

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HGVS	dbSNP	gnomAD frequency
NM_004360.5(CDH1):c.2520C>T (p.Ser840=)	rs140328601	0.00064
NM_004360.5(CDH1):c.892G>A (p.Ala298Thr)	rs142822590	0.00028
NM_004360.5(CDH1):c.303C>T (p.Tyr101=)	rs150789339	0.00027
NM_004360.5(CDH1):c.33G>C (p.Leu11=)	rs730881654	0.00022
NM_004360.5(CDH1):c.393C>T (p.Ser131=)	rs145430811	0.00006

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