ClinVar Miner

List of variants in gene ADAM17 reported as likely benign for immune system disorder

Included ClinVar conditions (908):
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:
Total variants: 102
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HGVS dbSNP gnomAD frequency
NM_003183.6(ADAM17):c.148A>G (p.Ile50Val) rs61754178 0.00443
NM_003183.6(ADAM17):c.232C>G (p.His78Asp) rs77759270 0.00312
NM_003183.6(ADAM17):c.435C>G (p.Ala145=) rs143124556 0.00075
NM_003183.6(ADAM17):c.178C>A (p.Leu60Ile) rs112594248 0.00071
NM_003183.6(ADAM17):c.231-14G>A rs370060861 0.00024
NM_003183.6(ADAM17):c.362-6C>T rs552450601 0.00019
NM_003183.6(ADAM17):c.321C>T (p.Tyr107=) rs576734742 0.00012
NM_003183.6(ADAM17):c.619+7C>T rs200004510 0.00009
NM_003183.6(ADAM17):c.204A>G (p.Thr68=) rs567931151 0.00008
NM_003183.6(ADAM17):c.97+18T>C rs375582202 0.00008
NM_003183.6(ADAM17):c.958-13_958-12insTG rs746257518 0.00007
NM_003183.6(ADAM17):c.450+18T>G rs780179175 0.00006
NM_003183.6(ADAM17):c.777T>C (p.Asp259=) rs146893995 0.00006
NM_003183.6(ADAM17):c.957+15C>G rs143463120 0.00005
NM_003183.6(ADAM17):c.309C>T (p.Asn103=) rs761183996 0.00004
NM_003183.6(ADAM17):c.462A>G (p.Arg154=) rs549352854 0.00004
NM_003183.6(ADAM17):c.97+8C>T rs981616407 0.00004
NM_003183.6(ADAM17):c.162G>A (p.Ser54=) rs762599369 0.00002
NM_003183.6(ADAM17):c.180A>G (p.Leu60=) rs776442513 0.00002
NM_003183.6(ADAM17):c.207A>G (p.Leu69=) rs141846970 0.00002
NM_003183.6(ADAM17):c.408T>C (p.Val136=) rs538546425 0.00002
NM_003183.6(ADAM17):c.451-15T>C rs376334773 0.00002
NM_003183.6(ADAM17):c.958-8T>G rs777073815 0.00002
NM_003183.6(ADAM17):c.1068C>T (p.Pro356=) rs750559090 0.00001
NM_003183.6(ADAM17):c.1083T>C (p.His361=) rs901073220 0.00001
NM_003183.6(ADAM17):c.1191+8_1191+20del rs780855948 0.00001
NM_003183.6(ADAM17):c.183G>A (p.Gln61=) rs768531855 0.00001
NM_003183.6(ADAM17):c.192A>G (p.Thr64=) rs760623120 0.00001
NM_003183.6(ADAM17):c.230+17A>G rs371770705 0.00001
NM_003183.6(ADAM17):c.230+9A>G rs375542168 0.00001
NM_003183.6(ADAM17):c.255A>G (p.Ser85=) rs1270237828 0.00001
NM_003183.6(ADAM17):c.267T>C (p.Arg89=) rs770087502 0.00001
NM_003183.6(ADAM17):c.354C>T (p.His118=) rs373534760 0.00001
NM_003183.6(ADAM17):c.362-11T>C rs1664944582 0.00001
NM_003183.6(ADAM17):c.516C>A (p.Ile172=) rs1572939240 0.00001
NM_003183.6(ADAM17):c.654A>G (p.Pro218=) rs755105372 0.00001
NM_003183.6(ADAM17):c.672G>T (p.Thr224=) rs757777916 0.00001
NM_003183.6(ADAM17):c.754-6A>G rs757613548 0.00001
NM_003183.6(ADAM17):c.75C>T (p.Gly25=) rs1427275550 0.00001
NM_003183.6(ADAM17):c.807T>C (p.Asn269=) rs200972600 0.00001
NM_003183.6(ADAM17):c.97+17G>C rs756580109 0.00001
NM_003183.6(ADAM17):c.1014C>T (p.Phe338=)
NM_003183.6(ADAM17):c.102G>A (p.Lys34=) rs1029893851
NM_003183.6(ADAM17):c.1103-12T>C
NM_003183.6(ADAM17):c.1103-20_1103-19del
NM_003183.6(ADAM17):c.1110T>C (p.Tyr370=)
NM_003183.6(ADAM17):c.1131T>C (p.Asn377=) rs2125017707
NM_003183.6(ADAM17):c.1143T>C (p.Asn381=)
NM_003183.6(ADAM17):c.1146T>C (p.Ser382=)
NM_003183.6(ADAM17):c.1191+19A>G
NM_003183.6(ADAM17):c.1191+20A>G
NM_003183.6(ADAM17):c.1191+8C>T rs1407294788
NM_003183.6(ADAM17):c.139T>C (p.Leu47=) rs2125040844
NM_003183.6(ADAM17):c.141A>G (p.Leu47=)
NM_003183.6(ADAM17):c.165A>T (p.Val55=) rs1572957857
NM_003183.6(ADAM17):c.180A>T (p.Leu60=)
NM_003183.6(ADAM17):c.208C>T (p.Leu70=)
NM_003183.6(ADAM17):c.228A>G (p.Lys76=)
NM_003183.6(ADAM17):c.258T>C (p.Ser86=)
NM_003183.6(ADAM17):c.276A>G (p.Gln92=) rs1293860750
NM_003183.6(ADAM17):c.27C>A (p.Thr9=) rs757690124
NM_003183.6(ADAM17):c.27C>T (p.Thr9=) rs757690124
NM_003183.6(ADAM17):c.288C>G (p.Val96=)
NM_003183.6(ADAM17):c.315C>T (p.Ser105=) rs552799044
NM_003183.6(ADAM17):c.361+13C>G
NM_003183.6(ADAM17):c.361+16G>T rs2125035383
NM_003183.6(ADAM17):c.361+17T>C rs191183953
NM_003183.6(ADAM17):c.361+19G>C
NM_003183.6(ADAM17):c.362-16T>C
NM_003183.6(ADAM17):c.362-18T>C
NM_003183.6(ADAM17):c.362-19A>C rs565512166
NM_003183.6(ADAM17):c.362-19A>T rs565512166
NM_003183.6(ADAM17):c.362-9del rs769247529
NM_003183.6(ADAM17):c.435C>T (p.Ala145=) rs143124556
NM_003183.6(ADAM17):c.450+17A>G rs751518092
NM_003183.6(ADAM17):c.558T>C (p.Tyr186=)
NM_003183.6(ADAM17):c.567G>A (p.Val189=) rs776034976
NM_003183.6(ADAM17):c.60T>G (p.Pro20=)
NM_003183.6(ADAM17):c.619+14A>C
NM_003183.6(ADAM17):c.620-5A>G
NM_003183.6(ADAM17):c.672G>A (p.Thr224=) rs757777916
NM_003183.6(ADAM17):c.678A>G (p.Lys226=)
NM_003183.6(ADAM17):c.72G>A (p.Pro24=) rs1476481051
NM_003183.6(ADAM17):c.754-20T>C
NM_003183.6(ADAM17):c.754-21_754-20del rs1558514870
NM_003183.6(ADAM17):c.754-4A>G rs2125023433
NM_003183.6(ADAM17):c.843+10A>T
NM_003183.6(ADAM17):c.843+11A>G
NM_003183.6(ADAM17):c.843+15A>T
NM_003183.6(ADAM17):c.844-17_844-16delinsTT rs2125021221
NM_003183.6(ADAM17):c.844-4A>G
NM_003183.6(ADAM17):c.867A>G (p.Gln289=) rs1553363787
NM_003183.6(ADAM17):c.870G>A (p.Glu290=)
NM_003183.6(ADAM17):c.873A>G (p.Val291=)
NM_003183.6(ADAM17):c.888G>A (p.Lys296=)
NM_003183.6(ADAM17):c.903A>G (p.Ala301=)
NM_003183.6(ADAM17):c.958-23_958-13del rs34863481
NM_003183.6(ADAM17):c.958-24_958-13del rs34863481
NM_003183.6(ADAM17):c.958-25_958-13del rs34863481
NM_003183.6(ADAM17):c.958-26_958-13del
NM_003183.6(ADAM17):c.958-5C>A rs768984675
NM_003183.6(ADAM17):c.97+12G>A

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