ClinVar Miner

List of variants in gene ICOS studied for immune system disorder

Included ClinVar conditions (908):
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:
Total variants: 158
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HGVS dbSNP gnomAD frequency
NM_012092.4(ICOS):c.587-26T>G rs10172036 0.57656
NM_012092.4(ICOS):c.*2A>C rs10183087 0.29378
NM_012092.4(ICOS):c.*964T>C rs4404254 0.29332
NM_012092.4(ICOS):c.*1407G>A rs1559931 0.29190
NM_012092.4(ICOS):c.*1773G>C rs4675379 0.14872
NM_012092.4(ICOS):c.*1262A>G rs10932038 0.08229
NM_012092.4(ICOS):c.*859A>T rs10932036 0.08225
NM_012092.4(ICOS):c.*330G>A rs10932035 0.08223
NM_012092.4(ICOS):c.*1024C>T rs10932037 0.08219
NM_012092.4(ICOS):c.*33T>C rs73058105 0.03775
NM_012092.4(ICOS):c.*1095A>G rs73991307 0.02660
NM_012092.4(ICOS):c.*855T>C rs73991306 0.02657
NM_012092.4(ICOS):c.150A>G (p.Gln50=) rs55972840 0.02252
NM_012092.4(ICOS):c.501+7G>A rs57149344 0.02252
NM_012092.4(ICOS):c.*1249G>A rs73991308 0.02203
NM_012092.4(ICOS):c.40C>T (p.Arg14Cys) rs77411896 0.00783
NM_012092.4(ICOS):c.*995C>T rs190590580 0.00677
NM_012092.4(ICOS):c.*1094C>T rs144036725 0.00599
NM_012092.4(ICOS):c.*1300C>T rs181937379 0.00360
NM_012092.4(ICOS):c.58+9T>G rs140049646 0.00348
NM_012092.4(ICOS):c.451G>C (p.Val151Leu) rs76778263 0.00226
NM_012092.4(ICOS):c.*1854G>A rs140979765 0.00184
NM_012092.4(ICOS):c.*1137C>T rs531066269 0.00123
NM_012092.4(ICOS):c.*1948G>T rs777338223 0.00080
NM_012092.4(ICOS):c.*1416G>T rs56259923 0.00071
NM_012092.4(ICOS):c.375A>G (p.Gly125=) rs768500706 0.00064
NM_012092.4(ICOS):c.589G>A (p.Val197Met) rs111644920 0.00037
NM_012092.4(ICOS):c.*1293T>C rs528769953 0.00032
NM_012092.4(ICOS):c.*399G>A rs760083763 0.00014
NM_012092.4(ICOS):c.438A>T (p.Gly146=) rs139449630 0.00014
NM_012092.4(ICOS):c.567C>G (p.Ala189=) rs373368532 0.00014
NM_012092.4(ICOS):c.*1004C>G rs866710563 0.00013
NM_012092.4(ICOS):c.*1869A>C rs931854904 0.00013
NM_012092.4(ICOS):c.591G>A (p.Val197=) rs55655222 0.00012
NM_012092.4(ICOS):c.531C>T (p.Asn177=) rs370645286 0.00011
NM_012092.4(ICOS):c.597A>G (p.Leu199=) rs145698501 0.00011
NM_012092.4(ICOS):c.106G>A (p.Gly36Arg) rs202109644 0.00009
NM_012092.4(ICOS):c.93T>C (p.Phe31=) rs147754976 0.00009
NM_012092.4(ICOS):c.*58T>G rs551768116 0.00008
NM_012092.4(ICOS):c.401A>C (p.Gln134Pro) rs367905290 0.00007
NM_012092.4(ICOS):c.*939A>G rs563893351 0.00006
NM_012092.4(ICOS):c.512C>A (p.Ser171Tyr) rs780326986 0.00006
NM_012092.4(ICOS):c.*77C>T rs769887283 0.00005
NM_012092.4(ICOS):c.*512T>C rs577478606 0.00004
NM_012092.4(ICOS):c.-24G>T rs576726896 0.00003
NM_012092.4(ICOS):c.42C>A (p.Arg14=) rs765158675 0.00003
NM_012092.4(ICOS):c.510A>G (p.Ser170=) rs148435889 0.00003
NM_012092.4(ICOS):c.*594C>T rs1391651175 0.00002
NM_012092.4(ICOS):c.*73T>C rs756570847 0.00002
NM_012092.4(ICOS):c.105C>T (p.Asn35=) rs201031378 0.00002
NM_012092.4(ICOS):c.356T>C (p.Phe119Ser) rs375299065 0.00002
NM_012092.4(ICOS):c.402A>G (p.Gln134=) rs776847112 0.00002
NM_012092.4(ICOS):c.45T>G (p.Ile15Met) rs762842725 0.00002
NM_012092.4(ICOS):c.471A>G (p.Gly157=) rs754099136 0.00002
NM_012092.4(ICOS):c.516T>C (p.Ser172=) rs150573153 0.00002
NM_012092.4(ICOS):c.584C>T (p.Thr195Ile) rs1044762811 0.00002
NM_012092.4(ICOS):c.586+20T>G rs750304925 0.00002
NM_012092.4(ICOS):c.59-3C>T rs764098873 0.00002
NM_012092.4(ICOS):c.77C>A (p.Ala26Asp) rs761695473 0.00002
NM_012092.4(ICOS):c.9A>C (p.Ser3=) rs1360705806 0.00002
NM_012092.4(ICOS):c.*1269A>C rs1430869619 0.00001
NM_012092.4(ICOS):c.*1457A>G rs749858926 0.00001
NM_012092.4(ICOS):c.*931A>G rs886055497 0.00001
NM_012092.4(ICOS):c.163T>C (p.Leu55=) rs1291412174 0.00001
NM_012092.4(ICOS):c.177G>A (p.Gly59=) rs775111991 0.00001
NM_012092.4(ICOS):c.189C>T (p.Cys63=) rs537195517 0.00001
NM_012092.4(ICOS):c.229A>G (p.Ile77Val) rs1048198057 0.00001
NM_012092.4(ICOS):c.271A>G (p.Ser91Gly) rs1314279149 0.00001
NM_012092.4(ICOS):c.390T>A (p.Ile130=) rs1257110059 0.00001
NM_012092.4(ICOS):c.411C>T (p.Cys137=) rs1260496726 0.00001
NM_012092.4(ICOS):c.496A>G (p.Lys166Glu) rs1297706917 0.00001
NM_012092.4(ICOS):c.522C>T (p.His174=) rs376555288 0.00001
NM_012092.4(ICOS):c.523G>A (p.Asp175Asn) rs778908715 0.00001
NM_012092.4(ICOS):c.580C>A (p.Leu194Ile) rs547175222 0.00001
NM_012092.4(ICOS):c.586+3A>G rs377370202 0.00001
NM_012092.4(ICOS):c.599A>G (p.Ter200=) rs1196963607 0.00001
NM_012092.4(ICOS):c.71G>T (p.Gly24Val) rs774325808 0.00001
NC_000002.11:g.(?_204820339)_(204824322_?)del
NM_012092.4(ICOS):c.*1025A>G rs77882417
NM_012092.4(ICOS):c.*1025A>T rs77882417
NM_012092.4(ICOS):c.*1093C>T rs886055499
NM_012092.4(ICOS):c.*1172G>A rs1581609062
NM_012092.4(ICOS):c.*1901A>G rs1690178448
NM_012092.4(ICOS):c.*474G>T rs558652067
NM_012092.4(ICOS):c.*977T>G rs886055498
NM_012092.4(ICOS):c.102C>T (p.His34=)
NM_012092.4(ICOS):c.128A>G (p.Lys43Arg) rs1367837109
NM_012092.4(ICOS):c.129A>T (p.Lys43Asn) rs1690065667
NM_012092.4(ICOS):c.136_139del (p.Asp46fs)
NM_012092.4(ICOS):c.13C>T (p.Leu5Phe) rs1689659275
NM_012092.4(ICOS):c.17G>A (p.Trp6Ter)
NM_012092.4(ICOS):c.181del (p.Ile61fs) rs1690066397
NM_012092.4(ICOS):c.184C>T (p.Leu62Phe) rs886055496
NM_012092.4(ICOS):c.186C>G (p.Leu62=) rs1553499319
NM_012092.4(ICOS):c.186C>T (p.Leu62=) rs1553499319
NM_012092.4(ICOS):c.189C>A (p.Cys63Ter) rs537195517
NM_012092.4(ICOS):c.190G>A (p.Asp64Asn)
NM_012092.4(ICOS):c.235A>C (p.Ser79Arg) rs2105754222
NM_012092.4(ICOS):c.249C>T (p.Cys83=)
NM_012092.4(ICOS):c.24C>A (p.Phe8Leu)
NM_012092.4(ICOS):c.291C>A (p.Tyr97Ter)
NM_012092.4(ICOS):c.294C>T (p.Asn98=) rs2105754276
NM_012092.4(ICOS):c.294del (p.Leu99fs)
NM_012092.4(ICOS):c.318T>G (p.Tyr106Ter) rs2105754294
NM_012092.4(ICOS):c.336A>G (p.Ser112=) rs1335754145
NM_012092.4(ICOS):c.357del (p.Phe119fs)
NM_012092.4(ICOS):c.376G>A (p.Gly126Arg) rs2105754334
NM_012092.4(ICOS):c.387T>C (p.His129=)
NM_012092.4(ICOS):c.394+14T>G
NM_012092.4(ICOS):c.394+17A>G
NM_012092.4(ICOS):c.394+19C>T
NM_012092.4(ICOS):c.394+2T>C rs1559035937
NM_012092.4(ICOS):c.394+7C>T rs2105754340
NM_012092.4(ICOS):c.394+9T>C rs1482892394
NM_012092.4(ICOS):c.395-10dup rs750240095
NM_012092.4(ICOS):c.395-15T>C rs2105754735
NM_012092.4(ICOS):c.395-17del
NM_012092.4(ICOS):c.395-18C>A
NM_012092.4(ICOS):c.395-19A>G
NM_012092.4(ICOS):c.395-4C>A
NM_012092.4(ICOS):c.406T>C (p.Cys136Arg) rs746054383
NM_012092.4(ICOS):c.416T>G (p.Leu139Arg)
NM_012092.4(ICOS):c.41G>A (p.Arg14His) rs776057192
NM_012092.4(ICOS):c.427T>C (p.Leu143=)
NM_012092.4(ICOS):c.43A>G (p.Ile15Val)
NM_012092.4(ICOS):c.451G>A (p.Val151Ile)
NM_012092.4(ICOS):c.466T>G (p.Leu156Val) rs1690083811
NM_012092.4(ICOS):c.477A>G (p.Ile159Met)
NM_012092.4(ICOS):c.495A>C (p.Thr165=) rs565719501
NM_012092.4(ICOS):c.501+12C>T
NM_012092.4(ICOS):c.501+16C>G
NM_012092.4(ICOS):c.501+6C>G rs4264550
NM_012092.4(ICOS):c.501+6C>T rs4264550
NM_012092.4(ICOS):c.502-6_502-5insG rs1690102674
NM_012092.4(ICOS):c.502A>C (p.Lys168Gln) rs1581607452
NM_012092.4(ICOS):c.509C>T (p.Ser170Leu) rs2105755520
NM_012092.4(ICOS):c.514A>G (p.Ser172Gly) rs2105755531
NM_012092.4(ICOS):c.523G>C (p.Asp175His)
NM_012092.4(ICOS):c.525C>T (p.Asp175=)
NM_012092.4(ICOS):c.547A>G (p.Met183Val) rs2105755568
NM_012092.4(ICOS):c.552A>G (p.Arg184=) rs1471545594
NM_012092.4(ICOS):c.555A>G (p.Ala185=)
NM_012092.4(ICOS):c.562_573del (p.Thr188_Lys191del) rs2105755576
NM_012092.4(ICOS):c.576T>C (p.Ser192=)
NM_012092.4(ICOS):c.578G>A (p.Arg193Lys)
NM_012092.4(ICOS):c.58+13T>C
NM_012092.4(ICOS):c.58+1G>A rs757598952
NM_012092.4(ICOS):c.58+20T>G
NM_012092.4(ICOS):c.58+4A>C rs2105741117
NM_012092.4(ICOS):c.586+11A>G
NM_012092.4(ICOS):c.586+12T>C rs2105755616
NM_012092.4(ICOS):c.586+2T>A rs1559036416
NM_012092.4(ICOS):c.59-16C>A rs745431176
NM_012092.4(ICOS):c.59-594_501+93del
NM_012092.4(ICOS):c.59-7T>C
NM_012092.4(ICOS):c.595C>T (p.Leu199=)
NM_012092.4(ICOS):c.61G>T (p.Glu21Ter) rs1015881666
NM_012092.4(ICOS):c.85G>A (p.Glu29Lys) rs977088960

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