List of variants reported as benign for colorectal neoplasm by Genome Diagnostics Laboratory, Amsterdam University Medical Center

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Total variants: 27

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HGVS	dbSNP	gnomAD frequency
NM_000535.7(PMS2):c.1532C>T (p.Thr511Met)	rs74902811	0.02492
NM_000249.4(MLH1):c.2152C>T (p.His718Tyr)	rs2020873	0.02345
NM_000251.3(MSH2):c.380A>G (p.Asn127Ser)	rs17217772	0.02317
NM_000535.7(PMS2):c.1488C>T (p.His496=)	rs1805320	0.02307
NM_000535.7(PMS2):c.1531A>G (p.Thr511Ala)	rs2228007	0.02174
NM_000179.3(MSH6):c.2253T>C (p.Asn751=)	rs2020913	0.02003
NM_000251.3(MSH2):c.573C>T (p.Leu191=)	rs1800151	0.01972
NM_000251.3(MSH2):c.965G>A (p.Gly322Asp)	rs4987188	0.01714
NM_000535.7(PMS2):c.1866G>A (p.Met622Ile)	rs1805324	0.01651
NM_000251.3(MSH2):c.1077-10T>C	rs17224360	0.01428
NM_000535.7(PMS2):c.1789A>T (p.Thr597Ser)	rs1805318	0.01006
NM_000249.4(MLH1):c.1959G>T (p.Leu653=)	rs1800146	0.00913
NM_000535.7(PMS2):c.52A>G (p.Ile18Val)	rs63750123	0.00861
NM_000179.3(MSH6):c.1186C>G (p.Leu396Val)	rs2020908	0.00565
NM_000179.3(MSH6):c.457+13A>G	rs1800933	0.00434
NM_000251.3(MSH2):c.1662-9G>A	rs17218356	0.00398
NM_000535.7(PMS2):c.1266G>A (p.Glu422=)	rs138049175	0.00348
NM_000251.3(MSH2):c.339G>A (p.Lys113=)	rs35898375	0.00313
NM_000179.3(MSH6):c.431G>T (p.Ser144Ile)	rs3211299	0.00158
NM_000249.4(MLH1):c.2146G>A (p.Val716Met)	rs35831931	0.00143
NM_000251.3(MSH2):c.1886A>G (p.Gln629Arg)	rs61756468	0.00042
NM_000251.3(MSH2):c.471C>A (p.Gly157=)	rs61756463	0.00029
NM_000535.7(PMS2):c.2324A>G (p.Asn775Ser)	rs17420802	0.00025
NM_000251.3(MSH2):c.212-4del	rs746333570
NM_000535.7(PMS2):c.1437C>G (p.His479Gln)	rs63750685
NM_000535.7(PMS2):c.1688G>T (p.Arg563Leu)	rs63750668
NM_000535.7(PMS2):c.706-5_706-4del	rs60794673

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