List of variants in gene LGI1 reported as pathogenic for brain disorder

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 36

Download table as spreadsheet

HGVS	dbSNP	gnomAD frequency
NM_005097.4(LGI1):c.406C>T (p.Arg136Trp)	rs119488099	0.00001
NM_005097.4(LGI1):c.988C>T (p.Arg330Ter)	rs1027289865	0.00001
NC_000010.10:g.(?_95517882)_(95537394_?)del
NC_000010.10:g.(?_95517902)_(95518136_?)del
NC_000010.11:g.(93704377_?)_(?_93785620)del
NM_005097.4(LGI1):c.1013T>C (p.Phe338Ser)	rs869025201
NM_005097.4(LGI1):c.108del (p.Lys36fs)	rs2133975489
NM_005097.4(LGI1):c.1104C>A (p.Tyr368Ter)
NM_005097.4(LGI1):c.1118T>A (p.Leu373Ter)	rs2134026513
NM_005097.4(LGI1):c.1128G>A (p.Trp376Ter)	rs1060502053
NM_005097.4(LGI1):c.1148A>C (p.Glu383Ala)	rs28937874
NM_005097.4(LGI1):c.1158_1168dup (p.Thr390delinsLysTer)	rs1554907767
NM_005097.4(LGI1):c.1252C>T (p.Gln418Ter)	rs2134026684
NM_005097.4(LGI1):c.1256T>G (p.Leu419Ter)	rs1554907787
NM_005097.4(LGI1):c.136T>C (p.Cys46Arg)	rs104894166
NM_005097.4(LGI1):c.1396C>T (p.Gln466Ter)
NM_005097.4(LGI1):c.1420C>T (p.Arg474Ter)	rs797044998
NM_005097.4(LGI1):c.1439_1442del (p.Gln480fs)	rs1554907835
NM_005097.4(LGI1):c.1442del (p.Pro481fs)	rs2134026964
NM_005097.4(LGI1):c.1465del (p.Tyr489fs)	rs1589776148
NM_005097.4(LGI1):c.1580_1581del (p.His527fs)	rs1364913665
NM_005097.4(LGI1):c.1599dup (p.Asn534Ter)	rs2134027169
NM_005097.4(LGI1):c.360-3C>A	rs1589762127
NM_005097.4(LGI1):c.365T>A (p.Ile122Lys)	rs119488100
NM_005097.4(LGI1):c.386C>G (p.Ser129Ter)	rs1564845068
NM_005097.4(LGI1):c.416del (p.Lys139fs)
NM_005097.4(LGI1):c.431+1G>A	rs2134001459
NM_005097.4(LGI1):c.443dup (p.Asn148fs)	rs2134017940
NM_005097.4(LGI1):c.446_449del (p.Asn149fs)	rs2134017952
NM_005097.4(LGI1):c.598del (p.Cys200fs)
NM_005097.4(LGI1):c.600C>A (p.Cys200Ter)
NM_005097.4(LGI1):c.611del (p.Pro204fs)
NM_005097.4(LGI1):c.688C>T (p.Gln230Ter)	rs1060502054
NM_005097.4(LGI1):c.695T>C (p.Leu232Pro)	rs104894167
NM_005097.4(LGI1):c.795G>A (p.Trp265Ter)	rs2134021516
NM_005097.4(LGI1):c.953T>G (p.Phe318Cys)	rs28939075

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.