ClinVar Miner

List of variants in gene MLH1 reported as likely benign for Lynch syndrome

Included ClinVar conditions (18):
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:
Total variants: 112
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HGVS dbSNP
NM_000249.3(MLH1):c.*32C>T rs200903126
NM_000249.3(MLH1):c.-107C>G rs587778886
NM_000249.3(MLH1):c.-269C>G rs35032294
NM_000249.3(MLH1):c.1003C>T (p.Leu335=) rs267607812
NM_000249.3(MLH1):c.1038+51C>T rs55986674
NM_000249.3(MLH1):c.1039-4A>G rs368618417
NM_000249.3(MLH1):c.1039-5T>C rs587782626
NM_000249.3(MLH1):c.1050A>G (p.Pro350=) rs137937003
NM_000249.3(MLH1):c.1104G>A (p.Ser368=) rs769364808
NM_000249.3(MLH1):c.1128T>C (p.Asp376=) rs267607824
NM_000249.3(MLH1):c.1136A>G (p.Tyr379Cys) rs143009528
NM_000249.3(MLH1):c.117-39G>A rs1057517605
NM_000249.3(MLH1):c.117-43_117-39del rs587778895
NM_000249.3(MLH1):c.117-48A>G rs377111182
NM_000249.3(MLH1):c.1210C>T (p.Leu404=) rs1057517538
NM_000249.3(MLH1):c.1266C>T (p.Gly422=) rs63750791
NM_000249.3(MLH1):c.1267A>G (p.Arg423Gly) rs1392665848
NM_000249.3(MLH1):c.1269G>A (p.Arg423=) rs373076967
NM_000249.3(MLH1):c.1284T>C (p.Asp428=) rs772555970
NM_000249.3(MLH1):c.1474G>A (p.Ala492Thr) rs63751145
NM_000249.3(MLH1):c.1558+3232_1558+3692delins2
NM_000249.3(MLH1):c.1587C>T (p.Ser529=) rs767089159
NM_000249.3(MLH1):c.1653C>T (p.Asn551=) rs587778936
NM_000249.3(MLH1):c.1731+14C>G rs745643356
NM_000249.3(MLH1):c.1731+8T>C rs370108219
NM_000249.3(MLH1):c.1732-19T>A rs77120160
NM_000249.3(MLH1):c.1732-9T>C rs267607857
NM_000249.3(MLH1):c.1743G>A (p.Pro581=) rs567838745
NM_000249.3(MLH1):c.1808C>G (p.Pro603Arg) rs63750876
NM_000249.3(MLH1):c.1853A>G (p.Lys618Arg) rs63750449
NM_000249.3(MLH1):c.1896+7C>T rs863224339
NM_000249.3(MLH1):c.18G>A (p.Gly6=) rs786202312
NM_000249.3(MLH1):c.1960C>T (p.Pro654Ser) rs1559591314
NM_000249.3(MLH1):c.1963A>G (p.Ile655Val) rs55907433
NM_000249.3(MLH1):c.198C>T (p.Thr66=) rs61751642
NM_000249.3(MLH1):c.1990-6G>A rs117221851
NM_000249.3(MLH1):c.2040C>T (p.Cys680=) rs63749867
NM_000249.3(MLH1):c.207+26del rs1057517621
NM_000249.3(MLH1):c.2088C>G (p.Thr696=) rs1060504015
NM_000249.3(MLH1):c.2101C>A (p.Gln701Lys) rs63750114
NM_000249.3(MLH1):c.2104-11G>A rs147984696
NM_000249.3(MLH1):c.2104-22T>C rs267607890
NM_000249.3(MLH1):c.2104-22T>G rs267607890
NM_000249.3(MLH1):c.2146G>A (p.Val716Met) rs35831931
NM_000249.3(MLH1):c.2172G>A (p.Leu724=) rs780045031
NM_000249.3(MLH1):c.2197C>T (p.His733Tyr) rs1553665846
NM_000249.3(MLH1):c.2252A>G (p.Lys751Arg) rs140195825
NM_000249.3(MLH1):c.253C>T (p.Leu85=) rs63750659
NM_000249.3(MLH1):c.303T>G (p.Gly101=) rs4647220
NM_000249.3(MLH1):c.307-10T>C rs572853043
NM_000249.3(MLH1):c.307-19A>G rs121909451
NM_000249.3(MLH1):c.351G>A (p.Thr117=) rs61751643
NM_000249.3(MLH1):c.375A>G (p.Ala125=) rs1800144
NM_000249.3(MLH1):c.381-43C>G rs368847278
NM_000249.3(MLH1):c.438A>G (p.Gln146=) rs377279035
NM_000249.3(MLH1):c.474C>T (p.Asn158=) rs4647256
NM_000249.3(MLH1):c.545+19G>T rs41285099
NM_000249.3(MLH1):c.545+43C>G rs267607761
NM_000249.3(MLH1):c.546-18T>C rs1057517622
NM_000249.3(MLH1):c.579A>G (p.Ser193=) rs587781038
NM_000249.3(MLH1):c.588+11G>C rs4647258
NM_000249.3(MLH1):c.589-15C>T rs55658850
NM_000249.3(MLH1):c.589-24T>C rs1057517607
NM_000249.3(MLH1):c.589-25G>A rs188146618
NM_000249.3(MLH1):c.636C>T (p.Thr212=) rs138735345
NM_000249.3(MLH1):c.677+7C>T rs556224377
NM_000249.3(MLH1):c.69A>G (p.Glu23=) rs63750555
NM_000249.3(MLH1):c.702G>A (p.Glu234=) rs35908749
NM_000249.3(MLH1):c.705T>C (p.Asp235=) rs876658869
NM_000249.3(MLH1):c.716C>T (p.Ala239Val) rs1559534371
NM_000249.3(MLH1):c.790+10A>G rs182733777
NM_000249.3(MLH1):c.790+17dup rs757064565
NM_000249.3(MLH1):c.791-14T>C rs751254837
NM_000249.3(MLH1):c.836T>G (p.Val279Gly) rs1553646683
NM_000249.3(MLH1):c.845C>G (p.Ala282Gly) rs63750360
NM_000249.3(MLH1):c.884+10C>T rs864622424
NM_000249.3(MLH1):c.884+10del rs878853793
NM_000249.3(MLH1):c.884+15A>G rs372817491
NM_000249.3(MLH1):c.884+16A>G rs377598055
NM_000249.3(MLH1):c.885-24T>A rs201594027
NM_000249.3(MLH1):c.885-5G>T rs267607802
NM_000249.3(MLH1):c.885-8C>T rs762836160
NM_000249.3(MLH1):c.927C>T (p.Pro309=) rs63749896
NM_000249.3(MLH1):c.954C>T (p.His318=) rs146777069
NM_000249.3(MLH1):c.974G>A (p.Arg325Gln) rs63750268
NM_000249.4(MLH1):c.-28A>G rs56198082
NM_000249.4(MLH1):c.1038+8C>T rs751872237
NM_000249.4(MLH1):c.1039-8T>A rs193922367
NM_000249.4(MLH1):c.1151T>A (p.Val384Asp) rs63750447
NM_000249.4(MLH1):c.116+27C>T
NM_000249.4(MLH1):c.1217G>A (p.Ser406Asn) rs41294980
NM_000249.4(MLH1):c.1281del (p.Asp428fs)
NM_000249.4(MLH1):c.1321G>A (p.Ala441Thr) rs63750365
NM_000249.4(MLH1):c.1379A>C (p.Glu460Ala) rs202038499
NM_000249.4(MLH1):c.1559-16A>T
NM_000249.4(MLH1):c.1742C>T (p.Pro581Leu) rs63751684
NM_000249.4(MLH1):c.1820T>A (p.Leu607His) rs41295284
NM_000249.4(MLH1):c.1852A>G (p.Lys618Glu) rs35001569
NM_000249.4(MLH1):c.1853A>C (p.Lys618Thr) rs63750449
NM_000249.4(MLH1):c.1897-17C>G rs2308316
NM_000249.4(MLH1):c.1959G>T (p.Leu653=) rs1800146
NM_000249.4(MLH1):c.1989+37T>C
NM_000249.4(MLH1):c.2066A>G (p.Gln689Arg) rs63750702
NM_000249.4(MLH1):c.207+523G>A
NM_000249.4(MLH1):c.2152C>T (p.His718Tyr) rs2020873
NM_000249.4(MLH1):c.637G>A (p.Val213Met) rs2308317
NM_000249.4(MLH1):c.885-21TC[2] rs267607804
NM_000249.4(MLH1):c.977T>C (p.Val326Ala) rs63751049
NM_001167617.2(MLH1):c.*158_*161GATT[1] rs796807655
NM_001167617.2(MLH1):c.*32_*34CTT[1] rs193922366
NM_001167617.2(MLH1):c.497-23del rs267607797
NM_001354630.1(MLH1):c.1732-878_1732-877delinsGC rs35502531

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