ClinVar Miner

List of variants in gene MSH2 reported as likely benign for Lynch syndrome

Included ClinVar conditions (18):
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:
Total variants: 153
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HGVS dbSNP
NM_000251.2(MSH2):c.*141T>G rs17225053
NM_000251.2(MSH2):c.*221G>T rs587779060
NM_000251.2(MSH2):c.*226A>G rs17225060
NM_000251.2(MSH2):c.-118T>C rs2303425
NM_000251.2(MSH2):c.-225G>C rs138068023
NM_000251.2(MSH2):c.1076+23C>G rs377417056
NM_000251.2(MSH2):c.1077-15G>T rs753277524
NM_000251.2(MSH2):c.1083T>C (p.Asn361=) rs864622544
NM_000251.2(MSH2):c.108T>C (p.Leu36=) rs876659034
NM_000251.2(MSH2):c.1114T>C (p.Leu372=) rs770201760
NM_000251.2(MSH2):c.1158T>C (p.Asp386=) rs1060504421
NM_000251.2(MSH2):c.115C>A (p.Arg39=) rs786202334
NM_000251.2(MSH2):c.1168C>T (p.Leu390Phe) rs17224367
NM_000251.2(MSH2):c.1194A>G (p.Ala398=) rs1060504412
NM_000251.2(MSH2):c.1209T>C (p.Asp403=) rs1060504420
NM_000251.2(MSH2):c.1255C>A (p.Gln419Lys) rs63750006
NM_000251.2(MSH2):c.1276+10G>A rs374061707
NM_000251.2(MSH2):c.1276+16G>A rs368120695
NM_000251.2(MSH2):c.1276+47T>A rs148018406
NM_000251.2(MSH2):c.1277-16T>C rs368653974
NM_000251.2(MSH2):c.12G>T (p.Gln4His) rs878853800
NM_000251.2(MSH2):c.1311G>T (p.Val437=) rs730881781
NM_000251.2(MSH2):c.1344C>T (p.Ser448=) rs1010360604
NM_000251.2(MSH2):c.1353G>A (p.Gln451=) rs1060504415
NM_000251.2(MSH2):c.135G>A (p.Ala45=) rs890172773
NM_000251.2(MSH2):c.1387-5T>C rs757458333
NM_000251.2(MSH2):c.1387-8G>T rs187525243
NM_000251.2(MSH2):c.138C>G (p.His46Gln) rs33946261
NM_000251.2(MSH2):c.1488A>G (p.Leu496=) rs267607960
NM_000251.2(MSH2):c.1510+11G>C rs370675562
NM_000251.2(MSH2):c.1511-41G>C rs202215396
NM_000251.2(MSH2):c.1511-9A>T rs12998837
NM_000251.2(MSH2):c.1560A>G (p.Gly520=) rs63750820
NM_000251.2(MSH2):c.1563T>C (p.Tyr521=) rs63750330
NM_000251.2(MSH2):c.156G>A (p.Leu52=) rs750241099
NM_000251.2(MSH2):c.1602T>A (p.Arg534=) rs267607965
NM_000251.2(MSH2):c.164G>A (p.Arg55Gln) rs748196422
NM_000251.2(MSH2):c.1661+12G>A rs3732183
NM_000251.2(MSH2):c.1661+17T>G rs377461923
NM_000251.2(MSH2):c.1661+6C>T rs267607973
NM_000251.2(MSH2):c.1661+9G>T rs1060504414
NM_000251.2(MSH2):c.1662-18T>C rs376235435
NM_000251.2(MSH2):c.1662-23A>G rs56404027
NM_000251.2(MSH2):c.1662-9G>A rs17218356
NM_000251.2(MSH2):c.1666T>C (p.Leu556=) rs61756466
NM_000251.2(MSH2):c.1680T>C (p.Asn560=) rs200056411
NM_000251.2(MSH2):c.1730T>C (p.Ile577Thr) rs63749910
NM_000251.2(MSH2):c.1737A>G (p.Lys579=) rs61756467
NM_000251.2(MSH2):c.1746C>A (p.Val582=) rs786201486
NM_000251.2(MSH2):c.1755T>C (p.Ser585=) rs63750112
NM_000251.2(MSH2):c.1759+16C>G rs1057517573
NM_000251.2(MSH2):c.1760-10T>A rs767536391
NM_000251.2(MSH2):c.1760-110_1760-108dup rs587779109
NM_000251.2(MSH2):c.1760-16T>G rs768370188
NM_000251.2(MSH2):c.1760-4A>G rs1060504409
NM_000251.2(MSH2):c.1850T>C (p.Val617Ala) rs1260310695
NM_000251.2(MSH2):c.1854A>G (p.Pro618=) rs786203744
NM_000251.2(MSH2):c.1884A>T (p.Gly628=) rs786202663
NM_000251.2(MSH2):c.1886A>G (p.Gln629Arg) rs61756468
NM_000251.2(MSH2):c.1963G>A (p.Val655Ile) rs549467183
NM_000251.2(MSH2):c.198C>T (p.Tyr66=) rs730881784
NM_000251.2(MSH2):c.2005+8dup rs267607992
NM_000251.2(MSH2):c.2006-26dup rs781614743
NM_000251.2(MSH2):c.2006-6T>C rs2303428
NM_000251.2(MSH2):c.2061C>G (p.Leu687=) rs63750032
NM_000251.2(MSH2):c.2076G>A (p.Gly692=) rs1060504422
NM_000251.2(MSH2):c.2088A>G (p.Pro696=) rs878853807
NM_000251.2(MSH2):c.2095T>C (p.Ser699Pro) rs1428704795
NM_000251.2(MSH2):c.2106G>A (p.Val702=) rs786201108
NM_000251.2(MSH2):c.211+8C>T rs267607916
NM_000251.2(MSH2):c.211+9C>G rs2303426
NM_000251.2(MSH2):c.2139G>C (p.Gly713=) rs63750003
NM_000251.2(MSH2):c.213A>G (p.Gly71=) rs878853808
NM_000251.2(MSH2):c.2154A>G (p.Gln718=) rs63750810
NM_000251.2(MSH2):c.2166C>A (p.Val722=) rs1057520969
NM_000251.2(MSH2):c.2166C>T (p.Val722=) rs1057520969
NM_000251.2(MSH2):c.21G>A (p.Glu7=) rs1060504423
NM_000251.2(MSH2):c.2205C>T (p.Ile735=) rs533553381
NM_000251.2(MSH2):c.2210+9A>G rs878853810
NM_000251.2(MSH2):c.2241A>T (p.Ile747=) rs1060504411
NM_000251.2(MSH2):c.2277A>G (p.Gly759=) rs1057520316
NM_000251.2(MSH2):c.2283G>A (p.Gly761=) rs755548149
NM_000251.2(MSH2):c.2317A>G (p.Lys773Glu) rs1558521813
NM_000251.2(MSH2):c.2322T>C (p.Ile774=) rs56397910
NM_000251.2(MSH2):c.23C>T (p.Thr8Met) rs17217716
NM_000251.2(MSH2):c.2400A>G (p.Leu800=) rs201298777
NM_000251.2(MSH2):c.2403T>C (p.His801=) rs1060504410
NM_000251.2(MSH2):c.2437A>G (p.Met813Val) rs63749841
NM_000251.2(MSH2):c.2458+12T>C rs1553369841
NM_000251.2(MSH2):c.2458+16G>A rs373624698
NM_000251.2(MSH2):c.2458+8C>G rs189025757
NM_000251.2(MSH2):c.2458+9T>C rs864622575
NM_000251.2(MSH2):c.2500G>A (p.Ala834Thr) rs63750757
NM_000251.2(MSH2):c.2545C>T (p.Leu849=) rs587778527
NM_000251.2(MSH2):c.2576_2584del (p.Glu859_Gln861del) rs587781278
NM_000251.2(MSH2):c.2579C>T (p.Ser860Leu) rs63750849
NM_000251.2(MSH2):c.2583A>G (p.Gln861=) rs63751093
NM_000251.2(MSH2):c.2634+12T>C rs372907481
NM_000251.2(MSH2):c.2681T>G (p.Met894Arg) rs1558526026
NM_000251.2(MSH2):c.2714C>G (p.Thr905Arg) rs267608022
NM_000251.2(MSH2):c.271G>C (p.Asp91His) rs1558457163
NM_000251.2(MSH2):c.2766T>C (p.Phe922=) rs55859129
NM_000251.2(MSH2):c.276T>G (p.Leu92=) rs1060504425
NM_000251.2(MSH2):c.2802G>A (p.Thr934=) rs150259097
NM_000251.2(MSH2):c.287G>A (p.Arg96His) rs63750002
NM_000251.2(MSH2):c.304G>A (p.Val102Ile) rs193922373
NM_000251.2(MSH2):c.333A>G (p.Ala111=) rs1060504408
NM_000251.2(MSH2):c.336C>A (p.Ser112=) rs34312619
NM_000251.2(MSH2):c.339G>A (p.Lys113=) rs35898375
NM_000251.2(MSH2):c.366+24A>G rs200890440
NM_000251.2(MSH2):c.366+25C>T rs764158568
NM_000251.2(MSH2):c.366+88G>A rs864622763
NM_000251.2(MSH2):c.367-19A>T rs730881783
NM_000251.2(MSH2):c.380A>G (p.Asn127Ser) rs17217772
NM_000251.2(MSH2):c.405C>G (p.Leu135=) rs778368203
NM_000251.2(MSH2):c.42G>A (p.Ala14=) rs374396150
NM_000251.2(MSH2):c.438T>C (p.Gly146=) rs587779161
NM_000251.2(MSH2):c.447T>C (p.Gly149=) rs786203142
NM_000251.2(MSH2):c.459C>T (p.Ser153=) rs63751065
NM_000251.2(MSH2):c.471C>A (p.Gly157=) rs61756463
NM_000251.2(MSH2):c.4G>A (p.Ala2Thr) rs63750466
NM_000251.2(MSH2):c.505A>G (p.Ile169Val) rs63750716
NM_000251.2(MSH2):c.531A>G (p.Glu177=) rs1060504416
NM_000251.2(MSH2):c.552C>T (p.Phe184=) rs786202238
NM_000251.2(MSH2):c.573C>T (p.Leu191=) rs1800151
NM_000251.2(MSH2):c.576C>T (p.Ile192=) rs864622381
NM_000251.2(MSH2):c.606C>T (p.Pro202=) rs63750600
NM_000251.2(MSH2):c.63C>T (p.Arg21=) rs1060504419
NM_000251.2(MSH2):c.6G>T (p.Ala2=) rs368270856
NM_000251.2(MSH2):c.726C>T (p.Asn242=) rs748427458
NM_000251.2(MSH2):c.762T>C (p.Asn254=) rs587779180
NM_000251.2(MSH2):c.763A>G (p.Ser255Gly) rs761529282
NM_000251.2(MSH2):c.798A>T (p.Ala266=) rs878853825
NM_000251.2(MSH2):c.837C>T (p.Leu279=) rs747730026
NM_000251.2(MSH2):c.843A>G (p.Ser281=) rs150197753
NM_000251.2(MSH2):c.84G>A (p.Glu28=) rs752220575
NM_000251.2(MSH2):c.888C>G (p.Phe296Leu) rs876659918
NM_000251.2(MSH2):c.896A>G (p.Tyr299Cys) rs1558464315
NM_000251.2(MSH2):c.933C>T (p.Asn311=) rs1060504424
NM_000251.2(MSH2):c.942+20_942+29del rs11309117
NM_000251.2(MSH2):c.943-25T>C rs775155213
NM_000251.2(MSH2):c.944G>T (p.Gly315Val) rs202026056
NM_000251.2(MSH2):c.965G>A (p.Gly322Asp) rs4987188
NM_000251.2(MSH2):c.966C>T (p.Gly322=) rs878853829
NM_000251.2(MSH2):c.972G>A (p.Gln324=) rs63750505
NM_000251.2(MSH2):c.975T>C (p.Ser325=) rs1060504413
NM_000251.2(MSH2):c.978G>C (p.Leu326=) rs1060504418
NM_000251.2(MSH2):c.984C>G (p.Ala328=) rs4987189
NM_000251.2(MSH2):c.984C>T (p.Ala328=) rs4987189
NM_000251.2(MSH2):c.991A>G (p.Asn331Asp) rs267607938
NM_001258281.1(MSH2):c.1313-10_1313-7del rs864622529
NM_001258281.1(MSH2):c.1463+25del rs1553366691
NM_001258281.1(MSH2):c.1561+11_1561+15del rs878853805

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