ClinVar Miner

List of variants reported as benign for Lynch syndrome

Included ClinVar conditions (18):
Minimum submission review status: Collection method:
Minimum conflict level:
ClinVar version:
Total variants: 231
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HGVS dbSNP
MSH6:c.3647-51_3647-35del17 rs267607687
NM_000179.2(MSH6):c.*4247G>A
NM_000179.2(MSH6):c.*5045T>C rs2537742
NM_000179.2(MSH6):c.-159C>T rs41540312
NM_000179.2(MSH6):c.-210C>T rs181096360
NM_000179.2(MSH6):c.-448G>A rs3136229
NM_000179.2(MSH6):c.-557T>G rs3136228
NM_000179.2(MSH6):c.1164C>T (p.His388=) rs55708305
NM_000179.2(MSH6):c.116G>A (p.Gly39Glu) rs1042821
NM_000179.2(MSH6):c.1186C>G (p.Leu396Val) rs2020908
NM_000179.2(MSH6):c.1345C>T (p.Leu449=) rs3136333
NM_000179.2(MSH6):c.1809G>A (p.Lys603=) rs876660790
NM_000179.2(MSH6):c.186C>A (p.Arg62=) rs1042820
NM_000179.2(MSH6):c.2253T>C (p.Asn751=) rs2020913
NM_000179.2(MSH6):c.2272C>T (p.Leu758=) rs56371757
NM_000179.2(MSH6):c.260+2214C>T rs3136245
NM_000179.2(MSH6):c.260+22C>G rs55927047
NM_000179.2(MSH6):c.260+2467A>G rs3136247
NM_000179.2(MSH6):c.261-1170G>T rs3136272
NM_000179.2(MSH6):c.261-36A>G rs1800931
NM_000179.2(MSH6):c.2633T>C (p.Val878Ala) rs2020912
NM_000179.2(MSH6):c.276A>G (p.Pro92=) rs1800932
NM_000179.2(MSH6):c.3172+171C>T rs3136337
NM_000179.2(MSH6):c.3173-101G>C rs2072447
NM_000179.2(MSH6):c.3246G>T (p.Pro1082=) rs3136351
NM_000179.2(MSH6):c.3306T>A (p.Thr1102=) rs2020910
NM_000179.2(MSH6):c.3438+14A>T rs2020911
NM_000179.2(MSH6):c.3439-16C>T rs192614006
NM_000179.2(MSH6):c.3556+146G>A rs7562048
NM_000179.2(MSH6):c.3556+160T>C rs56320267
NM_000179.2(MSH6):c.3557-3A>T rs41295274
NM_000179.2(MSH6):c.3646+35_3646+38delATCT rs1805181
NM_000179.2(MSH6):c.3646+35_3646+38dup rs1805181
NM_000179.2(MSH6):c.3646+91T>C rs3136359
NM_000179.2(MSH6):c.3647-35_3647-34insTTTGTTCTAATTCCTTT rs397515292
NM_000179.2(MSH6):c.3802-40C>G rs3136367
NM_000179.2(MSH6):c.3852G>T (p.Thr1284=) rs2229018
NM_000179.2(MSH6):c.4002-10delT rs59056100
NM_000179.2(MSH6):c.4002-11_4002-10dup rs59056100
NM_000179.2(MSH6):c.4002-12_4002-10dup rs59056100
NM_000179.2(MSH6):c.4002-13_4002-10dup rs59056100
NM_000179.2(MSH6):c.431G>T (p.Ser144Ile) rs3211299
NM_000179.2(MSH6):c.457+1223T>C rs2348244
NM_000179.2(MSH6):c.457+13A>G rs1800933
NM_000179.2(MSH6):c.457+394T>C rs3136284
NM_000179.2(MSH6):c.457+52T>A rs3136282
NM_000179.2(MSH6):c.458-52G>T rs1800934
NM_000179.2(MSH6):c.540T>C (p.Asp180=) rs1800935
NM_000179.2(MSH6):c.627+1200T>C rs3136326
NM_000179.2(MSH6):c.628-56C>T rs1800936
NM_000179.2(MSH6):c.628-874C>T rs3136329
NM_000179.2(MSH6):c.642C>T (p.Tyr214=) rs1800937
NM_000249.3(MLH1):c.*32_*34CTT[1] rs193922366
NM_000249.3(MLH1):c.-269C>G rs35032294
NM_000249.3(MLH1):c.-28A>G rs56198082
NM_000249.3(MLH1):c.-7C>T rs104894994
NM_000249.3(MLH1):c.-93G>A rs1800734
NM_000249.3(MLH1):c.1038+1005G>T rs3774338
NM_000249.3(MLH1):c.1038+51C>T rs55986674
NM_000249.3(MLH1):c.1038+86T>C rs2286939
NM_000249.3(MLH1):c.1039-10_1039-8dupTTT rs57509953
NM_000249.3(MLH1):c.1039-13_1039-8dupTTTTTT rs57509953
NM_000249.3(MLH1):c.1039-33_1039-29del rs148615368
NM_000249.3(MLH1):c.1039-78A>G rs11129748
NM_000249.3(MLH1):c.1039-8T>A rs193922367
NM_000249.3(MLH1):c.1039-8_1039-7insTTTTTTTTTTTTTTTTTTTTTTTTA rs535965616
NM_000249.3(MLH1):c.1040C>A (p.Thr347Asn) rs201541505
NM_000249.3(MLH1):c.1128T>C (p.Asp376=) rs267607824
NM_000249.3(MLH1):c.1151T>A (p.Val384Asp) rs63750447
NM_000249.3(MLH1):c.1217G>A (p.Ser406Asn) rs41294980
NM_000249.3(MLH1):c.1321G>A (p.Ala441Thr) rs63750365
NM_000249.3(MLH1):c.1410-54C>T rs7633154
NM_000249.3(MLH1):c.1558+14G>A rs41562513
NM_000249.3(MLH1):c.1558+2204A>C rs3774335
NM_000249.3(MLH1):c.1558+4245A>G rs3774332
NM_000249.3(MLH1):c.1559-3171A>G rs4678925
NM_000249.3(MLH1):c.1652A>G (p.Asn551Ser) rs63750271
NM_000249.3(MLH1):c.1668-19A>G rs9876116
NM_000249.3(MLH1):c.1668-254C>T rs41552415
NM_000249.3(MLH1):c.1668-885T>C rs748766
NM_000249.3(MLH1):c.1732-19T>A rs77120160
NM_000249.3(MLH1):c.1733A>G (p.Glu578Gly) rs63751612
NM_000249.3(MLH1):c.1799A>G (p.Glu600Gly) rs267607861
NM_000249.3(MLH1):c.1852_1853delinsGC (p.Lys618Ala) rs35502531
NM_000249.3(MLH1):c.1853A>C (p.Lys618Thr) rs63750449
NM_000249.3(MLH1):c.1959G>T (p.Leu653=) rs1800146
NM_000249.3(MLH1):c.1990-121C>T rs2241031
NM_000249.3(MLH1):c.2066A>G (p.Gln689Arg) rs63750702
NM_000249.3(MLH1):c.207+571C>T rs9852378
NM_000249.3(MLH1):c.2074T>C (p.Ser692Pro) rs587779957
NM_000249.3(MLH1):c.2146G>A (p.Val716Met) rs35831931
NM_000249.3(MLH1):c.2152C>T (p.His718Tyr) rs2020873
NM_000249.3(MLH1):c.306+416A>C rs4647222
NM_000249.3(MLH1):c.307-1403A>T rs1540354
NM_000249.3(MLH1):c.307-29C>A rs139620056
NM_000249.3(MLH1):c.381-41A>G rs4647245
NM_000249.3(MLH1):c.394G>C (p.Asp132His) rs28930073
NM_000249.3(MLH1):c.453+25A>G rs4647246
NM_000249.3(MLH1):c.453+554C>T rs267607748
NM_000249.3(MLH1):c.453+79A>G rs4234259
NM_000249.3(MLH1):c.454-51T>C rs4647255
NM_000249.3(MLH1):c.474C>T (p.Asn158=) rs4647256
NM_000249.3(MLH1):c.545+20A>T rs121909453
NM_000249.3(MLH1):c.588+11G>C rs4647258
NM_000249.3(MLH1):c.589-15C>T rs55658850
NM_000249.3(MLH1):c.637G>A (p.Val213Met) rs2308317
NM_000249.3(MLH1):c.655A>C (p.Ile219Leu) rs1799977
NM_000249.3(MLH1):c.655A>G (p.Ile219Val) rs1799977
NM_000249.3(MLH1):c.65G>C (p.Gly22Ala) rs41295280
NM_000249.3(MLH1):c.790+10A>G rs182733777
NM_000249.3(MLH1):c.790+955C>A rs1558528
NM_000249.3(MLH1):c.791-1406C>T rs4647269
NM_000249.3(MLH1):c.803A>G (p.Glu268Gly) rs63750650
NM_000249.3(MLH1):c.885-81G>C rs104894999
NM_000249.3(MLH1):c.977T>C (p.Val326Ala) rs63751049
NM_000251.2(MSH2):c.*129T>C rs587779059
NM_000251.2(MSH2):c.*251+2441A>C rs6544991
NM_000251.2(MSH2):c.*272+4059G>A rs6720549
NM_000251.2(MSH2):c.-118T>C rs2303425
NM_000251.2(MSH2):c.-68-365T>G rs1863332
NM_000251.2(MSH2):c.1076+3400C>T rs4952887
NM_000251.2(MSH2):c.1077-10T>C rs17224360
NM_000251.2(MSH2):c.1077-2037G>T rs13425206
NM_000251.2(MSH2):c.1077-80G>A rs2347794
NM_000251.2(MSH2):c.1168C>T (p.Leu390Phe) rs17224367
NM_000251.2(MSH2):c.1276+51C>A rs17217961
NM_000251.2(MSH2):c.1276+6765G>A rs3771274
NM_000251.2(MSH2):c.1277-118G>A rs1981929
NM_000251.2(MSH2):c.1277-212T>A rs1981928
NM_000251.2(MSH2):c.1277-5849T>C rs17036577
NM_000251.2(MSH2):c.1277-6990T>G rs13408008
NM_000251.2(MSH2):c.1277-945A>C rs7607312
NM_000251.2(MSH2):c.1387-250G>A rs6741393
NM_000251.2(MSH2):c.1387-8G>T rs187525243
NM_000251.2(MSH2):c.1511-1516C>T rs3771281
NM_000251.2(MSH2):c.1511-91G>T rs3732182
NM_000251.2(MSH2):c.1511-9A>T rs12998837
NM_000251.2(MSH2):c.1661+12G>A rs3732183
NM_000251.2(MSH2):c.1661+90T>C rs10183143
NM_000251.2(MSH2):c.1662-9G>A rs17218356
NM_000251.2(MSH2):c.1666T>C (p.Leu556=) rs61756466
NM_000251.2(MSH2):c.1690A>G (p.Thr564Ala) rs55778204
NM_000251.2(MSH2):c.1737A>G (p.Lys579=) rs61756467
NM_000251.2(MSH2):c.1759+501A>G rs17036614
NM_000251.2(MSH2):c.1760-62G>A rs17218439
NM_000251.2(MSH2):c.1886A>G (p.Gln629Arg) rs61756468
NM_000251.2(MSH2):c.2006-265A>G rs2059520
NM_000251.2(MSH2):c.2006-6T>C rs2303428
NM_000251.2(MSH2):c.211+98T>C rs3815865
NM_000251.2(MSH2):c.211+9C>G rs2303426
NM_000251.2(MSH2):c.212-4delT rs746333570
NM_000251.2(MSH2):c.2205C>A (p.Ile735=) rs533553381
NM_000251.2(MSH2):c.2210+274T>G rs4608577
NM_000251.2(MSH2):c.2210+317G>C rs4638843
NM_000251.2(MSH2):c.2355T>C (p.His785=) rs1114167840
NM_000251.2(MSH2):c.23C>T (p.Thr8Met) rs17217716
NM_000251.2(MSH2):c.2635-214T>C rs2042649
NM_000251.2(MSH2):c.273_275TCT[2] (p.Leu94del) rs267607919
NM_000251.2(MSH2):c.2766T>C (p.Phe922=) rs55859129
NM_000251.2(MSH2):c.317G>A (p.Arg106Lys) rs41295286
NM_000251.2(MSH2):c.339G>A (p.Lys113=) rs35898375
NM_000251.2(MSH2):c.380A>G (p.Asn127Ser) rs17217772
NM_000251.2(MSH2):c.471C>A (p.Gly157=) rs61756463
NM_000251.2(MSH2):c.499G>C (p.Asp167His) rs63750255
NM_000251.2(MSH2):c.573C>T (p.Leu191=) rs1800151
NM_000251.2(MSH2):c.593A>G (p.Glu198Gly) rs63750327
NM_000251.2(MSH2):c.7G>T (p.Val3Leu) rs1257347271
NM_000251.2(MSH2):c.815C>T (p.Ala272Val) rs34136999
NM_000251.2(MSH2):c.942+17_942+29delAAAAAAAAAAAAA rs11309117
NM_000251.2(MSH2):c.942+3_942+7delAAAAA rs11309117
NM_000251.2(MSH2):c.965G>A (p.Gly322Asp) rs4987188
NM_000535.6(PMS2):c.-154C>G rs3735296
NM_000535.6(PMS2):c.-195T>C rs2302336
NM_000535.6(PMS2):c.-93G>A rs6976537
NM_000535.6(PMS2):c.706-5_706-4delTT rs60794673
NM_000535.7(PMS2):c.*17G>C rs556089649
NM_000535.7(PMS2):c.*92dup rs267608145
NM_000535.7(PMS2):c.1266G>A (p.Glu422=) rs138049175
NM_000535.7(PMS2):c.1398C>T (p.Gly466=) rs752666485
NM_000535.7(PMS2):c.1408C>T (p.Pro470Ser) rs1805321
NM_000535.7(PMS2):c.1437C>G (p.His479Gln) rs63750685
NM_000535.7(PMS2):c.1454C>A (p.Thr485Lys) rs1805323
NM_000535.7(PMS2):c.1488C>T (p.His496=) rs1805320
NM_000535.7(PMS2):c.1531A>G (p.Thr511Ala) rs2228007
NM_000535.7(PMS2):c.1532C>T (p.Thr511Met) rs74902811
NM_000535.7(PMS2):c.1621= (p.Lys541=) rs2228006
NM_000535.7(PMS2):c.1621A>G (p.Lys541Glu) rs2228006
NM_000535.7(PMS2):c.164-108G>C rs12538294
NM_000535.7(PMS2):c.1688G>T (p.Arg563Leu) rs63750668
NM_000535.7(PMS2):c.1711C>A (p.Leu571Ile) rs63750055
NM_000535.7(PMS2):c.1789A>T (p.Thr597Ser) rs1805318
NM_000535.7(PMS2):c.1866G>A (p.Met622Ile) rs1805324
NM_000535.7(PMS2):c.2006+6G>A rs111905775
NM_000535.7(PMS2):c.2007-4G>A rs1805326
NM_000535.7(PMS2):c.2007-7C>T rs55954143
NM_000535.7(PMS2):c.2182A>G (p.Thr728Ala) rs141893001
NM_000535.7(PMS2):c.2187C>G (p.Leu729=) rs373630535
NM_000535.7(PMS2):c.2253T>C (p.Phe751=) rs1805325
NM_000535.7(PMS2):c.2324A>G (p.Asn775Ser) rs17420802
NM_000535.7(PMS2):c.2340C>T (p.Pro780=) rs142230276
NM_000535.7(PMS2):c.2466T>C (p.Leu822=) rs10000
NM_000535.7(PMS2):c.250+8G>A rs1057520511
NM_000535.7(PMS2):c.251-72A>G rs117831773
NM_000535.7(PMS2):c.2570G>C (p.Gly857Ala) rs1802683
NM_000535.7(PMS2):c.288C>T (p.Ala96=) rs12532895
NM_000535.7(PMS2):c.299A>G (p.Gln100Arg) rs747771951
NM_000535.7(PMS2):c.52A>G (p.Ile18Val) rs63750123
NM_000535.7(PMS2):c.538-223A>G rs2345060
NM_000535.7(PMS2):c.59G>A (p.Arg20Gln) rs10254120
NM_000535.7(PMS2):c.705+17A>G rs62456182
NM_000535.7(PMS2):c.706-20dup rs60794673
NM_000535.7(PMS2):c.706-4del rs60794673
NM_000535.7(PMS2):c.780C>G (p.Ser260=) rs1805319
NM_000535.7(PMS2):c.804-243G>A rs2286680
NM_000535.7(PMS2):c.993C>T (p.Cys331=) rs186577215
NM_001281492.1(MSH6):c.3167-4dup rs267608102
NM_001281492.1(MSH6):c.3412-43dup rs34154602
NM_002354.2(EPCAM):c.135A>G (p.Gln45=) rs72882770
NM_002354.2(EPCAM):c.159A>C (p.Ala53=) rs150562209
NM_002354.2(EPCAM):c.344T>C (p.Met115Thr) rs1126497
NM_002354.2(EPCAM):c.426-20A>G rs6744170
NM_002354.2(EPCAM):c.458G>C (p.Arg153Thr) rs189732445
NM_002354.2(EPCAM):c.63C>G (p.Ala21=) rs549177672
NM_002354.2(EPCAM):c.831A>G (p.Ile277Met) rs115283528
NM_002354.2(EPCAM):c.858G>A (p.Leu286=) rs138718438
NM_002354.2(EPCAM):c.859-7C>T rs72882786
NM_006303.4(AIMP2):c.-22C>A rs1062372
NM_006303.4(AIMP2):c.135+1667G>T rs77199218
NM_006303.4(AIMP2):c.135+2080A>T rs78453798
NM_006309.4(LRRFIP2):c.*272G>A rs10849
NM_014805.4(EPM2AIP1):c.*2570G>T rs9311149

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