ClinVar Miner

List of variants reported as likely benign for Lynch syndrome by Invitae

Included ClinVar conditions (18):
Minimum submission review status: Collection method:
Minimum conflict level:
ClinVar version:
Total variants: 275
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HGVS dbSNP
NM_000179.2(MSH6):c.1125G>A (p.Glu375=) rs1060504741
NM_000179.2(MSH6):c.1153A>C (p.Arg385=) rs781652274
NM_000179.2(MSH6):c.117G>A (p.Gly39=) rs756673077
NM_000179.2(MSH6):c.1182T>C (p.Ser394=) rs863224325
NM_000179.2(MSH6):c.1206C>T (p.Phe402=) rs779504190
NM_000179.2(MSH6):c.1269T>G (p.Leu423=) rs774457540
NM_000179.2(MSH6):c.1272C>T (p.Val424=) rs63751452
NM_000179.2(MSH6):c.135C>A (p.Gly45=) rs876659020
NM_000179.2(MSH6):c.1410A>G (p.Ser470=) rs863224326
NM_000179.2(MSH6):c.1419G>T (p.Leu473=) rs864622535
NM_000179.2(MSH6):c.1434T>C (p.Tyr478=) rs1057521265
NM_000179.2(MSH6):c.1443A>G (p.Ala481=) rs878853703
NM_000179.2(MSH6):c.1515T>C (p.Tyr505=) rs878853704
NM_000179.2(MSH6):c.1554C>T (p.Thr518=) rs786201471
NM_000179.2(MSH6):c.1581G>A (p.Leu527=) rs775618855
NM_000179.2(MSH6):c.1581G>T (p.Leu527=) rs775618855
NM_000179.2(MSH6):c.1623C>T (p.Ser541=) rs777678406
NM_000179.2(MSH6):c.1713T>G (p.Gly571=) rs781019496
NM_000179.2(MSH6):c.1716G>A (p.Gln572=) rs745772518
NM_000179.2(MSH6):c.1776A>G (p.Val592=) rs56132616
NM_000179.2(MSH6):c.1806A>C (p.Ser602=) rs1057520981
NM_000179.2(MSH6):c.1914T>G (p.Leu638=) rs766310490
NM_000179.2(MSH6):c.2013G>A (p.Leu671=) rs765289515
NM_000179.2(MSH6):c.204G>A (p.Lys68=) rs864622565
NM_000179.2(MSH6):c.207G>A (p.Ala69=) rs757025193
NM_000179.2(MSH6):c.2124A>G (p.Glu708=) rs781730324
NM_000179.2(MSH6):c.2193A>G (p.Gln731=) rs1055190211
NM_000179.2(MSH6):c.219C>T (p.Asn73=) rs1060504756
NM_000179.2(MSH6):c.2211A>C (p.Ala737=) rs780916013
NM_000179.2(MSH6):c.2227T>C (p.Leu743=) rs749308906
NM_000179.2(MSH6):c.2241G>C (p.Leu747=) rs377722465
NM_000179.2(MSH6):c.2250A>C (p.Thr750=) rs1060504746
NM_000179.2(MSH6):c.2319C>A (p.Leu773=) rs63749895
NM_000179.2(MSH6):c.2367T>C (p.Asn789=) rs1060504738
NM_000179.2(MSH6):c.2391C>T (p.Asp797=) rs754870044
NM_000179.2(MSH6):c.243G>T (p.Ala81=) rs1057523564
NM_000179.2(MSH6):c.246T>C (p.Pro82=) rs786201527
NM_000179.2(MSH6):c.2505G>A (p.Gln835=) rs863224328
NM_000179.2(MSH6):c.2547A>G (p.Thr849=) rs769018957
NM_000179.2(MSH6):c.255C>T (p.Pro85=) rs587779242
NM_000179.2(MSH6):c.2583T>A (p.Ala861=) rs1060504763
NM_000179.2(MSH6):c.2676T>G (p.Ser892=) rs863224329
NM_000179.2(MSH6):c.2682G>A (p.Gln894=) rs756239543
NM_000179.2(MSH6):c.2685A>T (p.Thr895=) rs749539614
NM_000179.2(MSH6):c.2688A>G (p.Lys896=) rs876659173
NM_000179.2(MSH6):c.2820T>A (p.Ala940=) rs878853722
NM_000179.2(MSH6):c.2901A>C (p.Ile967=) rs863224330
NM_000179.2(MSH6):c.2964C>T (p.Arg988=) rs144288981
NM_000179.2(MSH6):c.2997C>G (p.Thr999=) rs751279827
NM_000179.2(MSH6):c.3006C>T (p.Gly1002=) rs878853726
NM_000179.2(MSH6):c.3012A>G (p.Lys1004=) rs864622378
NM_000179.2(MSH6):c.3024C>G (p.Thr1008=) rs587780675
NM_000179.2(MSH6):c.3030T>C (p.Thr1010=) rs1060504753
NM_000179.2(MSH6):c.3072G>A (p.Arg1024=) rs878853728
NM_000179.2(MSH6):c.30C>T (p.Phe10=) rs786201869
NM_000179.2(MSH6):c.3201T>C (p.Ser1067=) rs878853731
NM_000179.2(MSH6):c.3204A>T (p.Arg1068=) rs1060504764
NM_000179.2(MSH6):c.3213T>C (p.Asp1071=) rs534232216
NM_000179.2(MSH6):c.3255C>A (p.Thr1085=) rs371568610
NM_000179.2(MSH6):c.3258C>T (p.Pro1086=) rs863224331
NM_000179.2(MSH6):c.3261C>G (p.Pro1087=) rs370226185
NM_000179.2(MSH6):c.3327T>C (p.Ile1109=) rs878853733
NM_000179.2(MSH6):c.3435A>G (p.Arg1145=) rs1060504742
NM_000179.2(MSH6):c.3438+17G>C rs759737239
NM_000179.2(MSH6):c.3439-8A>G rs863224332
NM_000179.2(MSH6):c.3486T>C (p.Ala1162=) rs781119463
NM_000179.2(MSH6):c.3492G>A (p.Val1164=) rs1060504745
NM_000179.2(MSH6):c.3510T>C (p.Ile1170=) rs1001812170
NM_000179.2(MSH6):c.3556+10T>C rs863224333
NM_000179.2(MSH6):c.3570T>C (p.Phe1190=) rs1060504765
NM_000179.2(MSH6):c.3579A>G (p.Glu1193=) rs1060504759
NM_000179.2(MSH6):c.3625C>T (p.Leu1209=) rs753675331
NM_000179.2(MSH6):c.3657T>C (p.Thr1219=) rs745491567
NM_000179.2(MSH6):c.3711G>A (p.Glu1237=) rs754289472
NM_000179.2(MSH6):c.3720A>G (p.Lys1240=) rs786203260
NM_000179.2(MSH6):c.3801+8C>A rs864622734
NM_000179.2(MSH6):c.3802-8T>G rs864622195
NM_000179.2(MSH6):c.381C>T (p.Val127=) rs863224334
NM_000179.2(MSH6):c.3861T>C (p.Tyr1287=) rs1060504739
NM_000179.2(MSH6):c.3882T>C (p.Cys1294=) rs1060504744
NM_000179.2(MSH6):c.393A>G (p.Val131=) rs752488540
NM_000179.2(MSH6):c.4001+11_4001+15dupAACTA rs587779302
NM_000179.2(MSH6):c.4001+11_4001+35delAACTATAATGGAATTATAACTAACT rs878853743
NM_000179.2(MSH6):c.4001+12_4001+15dupACTA rs267608132
NM_000179.2(MSH6):c.4002-11_4002-4delTTAATTTT rs1060504752
NM_000179.2(MSH6):c.4002-4T>C rs370428032
NM_000179.2(MSH6):c.4002-8A>T rs778957100
NM_000179.2(MSH6):c.4002-8delA rs267608139
NM_000179.2(MSH6):c.4012C>T (p.Leu1338=) rs1060504743
NM_000179.2(MSH6):c.417A>G (p.Thr139=) rs758390144
NM_000179.2(MSH6):c.458-5delT rs587781955
NM_000179.2(MSH6):c.458-6T>C rs1060504740
NM_000179.2(MSH6):c.458-8C>G rs372091232
NM_000179.2(MSH6):c.552T>C (p.Asn184=) rs786203679
NM_000179.2(MSH6):c.60C>T (p.Ala20=) rs878853749
NM_000179.2(MSH6):c.627+9C>T rs373155872
NM_000179.2(MSH6):c.747G>A (p.Arg249=) rs63750372
NM_000179.2(MSH6):c.846G>C (p.Val282=) rs573638836
NM_000179.2(MSH6):c.84A>T (p.Ser28=) rs1060504748
NM_000179.2(MSH6):c.927T>C (p.Ser309=) rs771288794
NM_000179.2(MSH6):c.993A>G (p.Ser331=) rs1060504750
NM_000249.3(MLH1):c.1005G>A (p.Leu335=) rs1060504008
NM_000249.3(MLH1):c.1008C>A (p.Gly336=) rs863224338
NM_000249.3(MLH1):c.1035C>T (p.Thr345=) rs758668630
NM_000249.3(MLH1):c.1039-8_1039-7insTTTTTTTTTTTTTTTTTTTTTTTTTTTTA rs535965616
NM_000249.3(MLH1):c.1039-9T>G rs1060504009
NM_000249.3(MLH1):c.116+10_116+12delGAG rs1060504007
NM_000249.3(MLH1):c.116+8G>A rs904872305
NM_000249.3(MLH1):c.1164C>T (p.Ser388=) rs1060504014
NM_000249.3(MLH1):c.117-9A>G rs1060504004
NM_000249.3(MLH1):c.1185A>G (p.Ala395=) rs878853774
NM_000249.3(MLH1):c.1407C>G (p.Pro469=) rs1060504002
NM_000249.3(MLH1):c.1407C>T (p.Pro469=) rs1060504002
NM_000249.3(MLH1):c.144A>G (p.Gln48=) rs147342421
NM_000249.3(MLH1):c.1554T>C (p.His518=) rs1060504010
NM_000249.3(MLH1):c.1559-8T>C rs753196249
NM_000249.3(MLH1):c.159G>A (p.Glu53=) rs1060504012
NM_000249.3(MLH1):c.1732-5C>T rs587778941
NM_000249.3(MLH1):c.1732-6T>C rs878853782
NM_000249.3(MLH1):c.1818A>G (p.Gly606=) rs1057522427
NM_000249.3(MLH1):c.1824T>A (p.Ala608=) rs876659019
NM_000249.3(MLH1):c.1872C>T (p.Asp624=) rs145535636
NM_000249.3(MLH1):c.1983C>T (p.Ala661=) rs1060504001
NM_000249.3(MLH1):c.1990-9T>C rs756846181
NM_000249.3(MLH1):c.1995T>C (p.Asn665=) rs1060504011
NM_000249.3(MLH1):c.2010G>A (p.Lys670=) rs1060504013
NM_000249.3(MLH1):c.208-9A>G rs1057523558
NM_000249.3(MLH1):c.2082G>A (p.Glu694=) rs1057521441
NM_000249.3(MLH1):c.2103+10_2103+14delTGATG rs864622755
NM_000249.3(MLH1):c.261C>T (p.Ser87=) rs63750923
NM_000249.3(MLH1):c.306+8A>G rs587779002
NM_000249.3(MLH1):c.307-10T>C rs572853043
NM_000249.3(MLH1):c.330G>A (p.Val110=) rs863224340
NM_000249.3(MLH1):c.381-5A>C rs1060504016
NM_000249.3(MLH1):c.42A>G (p.Thr14=) rs369737664
NM_000249.3(MLH1):c.546-9C>G rs878853789
NM_000249.3(MLH1):c.588+8C>A rs1060504005
NM_000249.3(MLH1):c.589-7T>C rs371767464
NM_000249.3(MLH1):c.589-9G>A rs566497442
NM_000249.3(MLH1):c.621A>G (p.Leu207=) rs770554901
NM_000249.3(MLH1):c.756A>C (p.Ser252=) rs864622458
NM_000249.3(MLH1):c.81G>A (p.Arg27=) rs878853791
NM_000249.3(MLH1):c.884+10delC rs878853793
NM_000249.3(MLH1):c.906T>C (p.Asn302=) rs1060504006
NM_000249.3(MLH1):c.939A>G (p.Glu313=) rs864622432
NM_000251.2(MSH2):c.-225G>C rs138068023
NM_000251.2(MSH2):c.1083T>C (p.Asn361=) rs864622544
NM_000251.2(MSH2):c.1114T>C (p.Leu372=) rs770201760
NM_000251.2(MSH2):c.1158T>C (p.Asp386=) rs1060504421
NM_000251.2(MSH2):c.1194A>G (p.Ala398=) rs1060504412
NM_000251.2(MSH2):c.1209T>C (p.Asp403=) rs1060504420
NM_000251.2(MSH2):c.1353G>A (p.Gln451=) rs1060504415
NM_000251.2(MSH2):c.135G>A (p.Ala45=) rs890172773
NM_000251.2(MSH2):c.1387-5T>C rs757458333
NM_000251.2(MSH2):c.1511-10_1511-7delGATT rs864622529
NM_000251.2(MSH2):c.1511-41G>C rs202215396
NM_000251.2(MSH2):c.156G>A (p.Leu52=) rs750241099
NM_000251.2(MSH2):c.1661+9G>T rs1060504414
NM_000251.2(MSH2):c.1746C>A (p.Val582=) rs786201486
NM_000251.2(MSH2):c.1759+11_1759+15delTAGAA rs878853805
NM_000251.2(MSH2):c.1760-4A>G rs1060504409
NM_000251.2(MSH2):c.2076G>A (p.Gly692=) rs1060504422
NM_000251.2(MSH2):c.2088A>G (p.Pro696=) rs878853807
NM_000251.2(MSH2):c.2106G>A (p.Val702=) rs786201108
NM_000251.2(MSH2):c.2166C>A (p.Val722=) rs1057520969
NM_000251.2(MSH2):c.2166C>T (p.Val722=) rs1057520969
NM_000251.2(MSH2):c.21G>A (p.Glu7=) rs1060504423
NM_000251.2(MSH2):c.2210+9A>G rs878853810
NM_000251.2(MSH2):c.2241A>T (p.Ile747=) rs1060504411
NM_000251.2(MSH2):c.2277A>G (p.Gly759=) rs1057520316
NM_000251.2(MSH2):c.2283G>A (p.Gly761=) rs755548149
NM_000251.2(MSH2):c.2322T>C (p.Ile774=) rs56397910
NM_000251.2(MSH2):c.2403T>C (p.His801=) rs1060504410
NM_000251.2(MSH2):c.2458+9T>C rs864622575
NM_000251.2(MSH2):c.2545C>T (p.Leu849=) rs587778527
NM_000251.2(MSH2):c.276T>G (p.Leu92=) rs1060504425
NM_000251.2(MSH2):c.333A>G (p.Ala111=) rs1060504408
NM_000251.2(MSH2):c.366+88G>A rs864622763
NM_000251.2(MSH2):c.405C>G (p.Leu135=) rs778368203
NM_000251.2(MSH2):c.447T>C (p.Gly149=) rs786203142
NM_000251.2(MSH2):c.531A>G (p.Glu177=) rs1060504416
NM_000251.2(MSH2):c.552C>T (p.Phe184=) rs786202238
NM_000251.2(MSH2):c.576C>T (p.Ile192=) rs864622381
NM_000251.2(MSH2):c.63C>T (p.Arg21=) rs1060504419
NM_000251.2(MSH2):c.726C>T (p.Asn242=) rs748427458
NM_000251.2(MSH2):c.798A>T (p.Ala266=) rs878853825
NM_000251.2(MSH2):c.837C>T (p.Leu279=) rs747730026
NM_000251.2(MSH2):c.843A>G (p.Ser281=) rs150197753
NM_000251.2(MSH2):c.84G>A (p.Glu28=) rs752220575
NM_000251.2(MSH2):c.933C>T (p.Asn311=) rs1060504424
NM_000251.2(MSH2):c.942+20_942+29del rs11309117
NM_000251.2(MSH2):c.966C>T (p.Gly322=) rs878853829
NM_000251.2(MSH2):c.975T>C (p.Ser325=) rs1060504413
NM_000251.2(MSH2):c.978G>C (p.Leu326=) rs1060504418
NM_000251.2(MSH2):c.984C>G (p.Ala328=) rs4987189
NM_000535.6(PMS2):c.538-5_538-4delAA rs1060504839
NM_000535.7(PMS2):c.1125G>A (p.Gln375=) rs1060504838
NM_000535.7(PMS2):c.1134G>T (p.Leu378=) rs754576828
NM_000535.7(PMS2):c.1191A>G (p.Val397=) rs864622595
NM_000535.7(PMS2):c.1203T>C (p.Asp401=) rs1057522327
NM_000535.7(PMS2):c.120G>A (p.Lys40=) rs1060504843
NM_000535.7(PMS2):c.1326A>G (p.Pro442=) rs878854034
NM_000535.7(PMS2):c.1371C>T (p.Ser457=) rs1060504840
NM_000535.7(PMS2):c.1587G>A (p.Ser529=) rs786201709
NM_000535.7(PMS2):c.1632C>T (p.Asp544=) rs786203439
NM_000535.7(PMS2):c.164-6T>C rs1060504837
NM_000535.7(PMS2):c.171G>A (p.Lys57=) rs760031402
NM_000535.7(PMS2):c.1790C>G (p.Thr597Ser) rs878854038
NM_000535.7(PMS2):c.1803A>G (p.Ser601=) rs864622203
NM_000535.7(PMS2):c.1854G>C (p.Leu618=) rs876660784
NM_000535.7(PMS2):c.1902T>C (p.His634=) rs376335675
NM_000535.7(PMS2):c.2007-10C>T rs878854042
NM_000535.7(PMS2):c.2013G>A (p.Thr671=) rs771513870
NM_000535.7(PMS2):c.2106C>T (p.Ala702=) rs786202273
NM_000535.7(PMS2):c.2112C>T (p.Asp704=) rs764735061
NM_000535.7(PMS2):c.2127C>T (p.Phe709=) rs199943748
NM_000535.7(PMS2):c.2166G>A (p.Arg722=) rs863224367
NM_000535.7(PMS2):c.2199T>C (p.Ala733=) rs876658952
NM_000535.7(PMS2):c.21G>C (p.Ser7=) rs587780726
NM_000535.7(PMS2):c.2202T>C (p.Val734=) rs878854044
NM_000535.7(PMS2):c.2265C>T (p.Ile755=) rs145646046
NM_000535.7(PMS2):c.2275+8A>G rs878854046
NM_000535.7(PMS2):c.2276-10A>G rs573900018
NM_000535.7(PMS2):c.23+7G>A rs878854047
NM_000535.7(PMS2):c.2358G>C (p.Leu786=) rs535056715
NM_000535.7(PMS2):c.2373C>T (p.Ser791=) rs864622765
NM_000535.7(PMS2):c.2385G>T (p.Gly795=) rs372868520
NM_000535.7(PMS2):c.2388C>T (p.Val796=) rs876660875
NM_000535.7(PMS2):c.2446-5C>T rs864622279
NM_000535.7(PMS2):c.2469C>T (p.Asn823=) rs878854048
NM_000535.7(PMS2):c.2538A>G (p.Gly846=) rs863224368
NM_000535.7(PMS2):c.2559C>T (p.Ile853=) rs371673459
NM_000535.7(PMS2):c.2562C>T (p.Ala854=) rs1060504841
NM_000535.7(PMS2):c.2565C>T (p.Asn855=) rs864622494
NM_000535.7(PMS2):c.27A>C (p.Thr9=) rs1060504842
NM_000535.7(PMS2):c.372C>T (p.Thr124=) rs1060504836
NM_000535.7(PMS2):c.381A>G (p.Ala127=) rs1060504835
NM_000535.7(PMS2):c.387G>A (p.Ala129=) rs876658275
NM_000535.7(PMS2):c.465C>A (p.Thr155=) rs863224369
NM_000535.7(PMS2):c.504G>A (p.Val168=) rs878854053
NM_000535.7(PMS2):c.54T>C (p.Ile18=) rs878854054
NM_000535.7(PMS2):c.684C>T (p.Gly228=) rs371876208
NM_000535.7(PMS2):c.87G>A (p.Gly29=) rs876659642
NM_000535.7(PMS2):c.97C>T (p.Leu33=) rs878854061
NM_002354.2(EPCAM):c.141G>A (p.Gln47=) rs186094931
NM_002354.2(EPCAM):c.147T>C (p.Thr49=) rs190508047
NM_002354.2(EPCAM):c.165T>C (p.Asn55=) rs201645229
NM_002354.2(EPCAM):c.171C>A (p.Val57=) rs369992289
NM_002354.2(EPCAM):c.185-9C>A rs863224388
NM_002354.2(EPCAM):c.21C>T (p.Leu7=) rs878854487
NM_002354.2(EPCAM):c.288T>C (p.Asp96=) rs864622181
NM_002354.2(EPCAM):c.297C>T (p.Cys99=) rs143264703
NM_002354.2(EPCAM):c.304A>G (p.Ser102Gly) rs34474955
NM_002354.2(EPCAM):c.342C>T (p.Ser114=) rs200495968
NM_002354.2(EPCAM):c.360C>T (p.Asn120=) rs371217745
NM_002354.2(EPCAM):c.390C>T (p.Asp130=) rs863224389
NM_002354.2(EPCAM):c.459A>G (p.Arg153=) rs878854489
NM_002354.2(EPCAM):c.487C>T (p.Arg163Trp) rs148725106
NM_002354.2(EPCAM):c.491+10A>G rs751317067
NM_002354.2(EPCAM):c.501G>A (p.Gln167=) rs754990754
NM_002354.2(EPCAM):c.516G>A (p.Thr172=) rs371372017
NM_002354.2(EPCAM):c.555+7T>A rs864622648
NM_002354.2(EPCAM):c.558T>C (p.Tyr186=) rs878854492
NM_002354.2(EPCAM):c.597T>C (p.Ser199=) rs587780770
NM_002354.2(EPCAM):c.6G>T (p.Ala2=) rs374563131
NM_002354.2(EPCAM):c.729T>C (p.Asp243=) rs864622420
NM_002354.2(EPCAM):c.762A>G (p.Glu254=) rs863224390
NM_002354.2(EPCAM):c.859-6A>C rs150307203
NM_002354.2(EPCAM):c.903+7G>T rs756176396
NM_002354.2(EPCAM):c.903+9A>T rs863224391
NM_002354.2(EPCAM):c.904-6T>C rs747578954
NM_002354.2(EPCAM):c.904-7G>C rs753816014
NM_002354.2(EPCAM):c.921G>A (p.Glu307=) rs878854497
NM_002354.2(EPCAM):c.93C>G (p.Asn31Lys) rs555329870
NM_002354.2(EPCAM):c.99G>A (p.Lys33=) rs878854498

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