ClinVar Miner

List of variants reported as likely benign for malignant mixed neoplasm by Illumina Laboratory Services, Illumina

Included ClinVar conditions (20):

Aniridia 1; Drash syndrome; Frasier syndrome; Meacham syndrome; Mesothelioma, malignant; Nephrotic syndrome, type 4; Wilms tumor 1; 11p partial monosomy syndrome
Autosomal dominant nonsyndromic hearing loss 27; Wilms tumor 6; Fibromatosis, gingival, 5
Beckwith-Wiedemann syndrome; Wilms tumor 1; Silver-Russell syndrome 1; Silver-Russell syndrome 3
Drash syndrome; Frasier syndrome; Meacham syndrome; Mesothelioma, malignant; Nephrotic syndrome, type 4; Wilms tumor 1
Drash syndrome; Frasier syndrome; Nephrotic syndrome, type 4; Wilms tumor 1
Drash syndrome; Frasier syndrome; Wilms tumor 1
Drash syndrome; Frasier syndrome; Wilms tumor 1; 11p partial monosomy syndrome
Familial cancer of breast; Breast-ovarian cancer, familial, susceptibility to, 2; Fanconi anemia complementation group D1; Medulloblastoma; Wilms tumor 1; Glioma susceptibility 3; Familial prostate cancer
Familial cancer of breast; Breast-ovarian cancer, familial, susceptibility to, 2; Fanconi anemia complementation group D1; Medulloblastoma; Wilms tumor 1; Malignant tumor of prostate; Pancreatic cancer, susceptibility to, 2; Glioma susceptibility 3
Familial cancer of breast; Breast-ovarian cancer, familial, susceptibility to, 2; Fanconi anemia complementation group D1; Medulloblastoma; Wilms tumor 1; Malignant tumor of prostate; Pancreatic cancer, susceptibility to, 2; Glioma susceptibility 3; Melanoma, cutaneous malignant, susceptibility to, 1
Familial cancer of breast; Breast-ovarian cancer, familial, susceptibility to, 2; Fanconi anemia complementation group D1; Medulloblastoma; Wilms tumor 1; Malignant tumor of prostate; Pancreatic cancer, susceptibility to, 2; Glioma susceptibility 3; Tracheoesophageal fistula
Familial cancer of breast; Breast-ovarian cancer, familial, susceptibility to, 2; Fanconi anemia complementation group D1; Medulloblastoma; Wilms tumor 1; Pancreatic cancer, susceptibility to, 2; Glioma susceptibility 3; Familial prostate cancer
Keipert syndrome; Wilms tumor 1; Simpson-Golabi-Behmel syndrome type 1
Nephroblastoma
Uterine carcinosarcoma
Wilms tumor 1
Wilms tumor 1; Simpson-Golabi-Behmel syndrome type 1
Wilms tumor 2
Wilms tumor 5
Wilms tumor 6

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 14

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HGVS	dbSNP	gnomAD frequency
NM_024426.6(WT1):c.*897G>C	rs5030324	0.00520
NM_024426.6(WT1):c.*542G>A	rs142726499	0.00380
NM_024426.6(WT1):c.181C>A (p.Arg61=)	rs2234581	0.00270
NM_024426.6(WT1):c.*138G>A	rs111351882	0.00165
NM_024426.6(WT1):c.1131T>C (p.Pro377=)	rs151034312	0.00047
NM_024426.6(WT1):c.375C>T (p.Gly125=)	rs776209354	0.00039
NM_024426.6(WT1):c.216G>T (p.Gln72His)	rs5030135	0.00036
NM_024426.6(WT1):c.*12C>T	rs77462662	0.00034
NM_024426.6(WT1):c.760C>T (p.Pro254Ser)	rs2234584	0.00022
NM_024426.6(WT1):c.1017-9T>C	rs368486676	0.00007
NM_024426.6(WT1):c.696C>T (p.Ser232=)	rs9332974	0.00006
NM_024426.6(WT1):c.1124G>A (p.Arg375His)	rs554416372	0.00003
NM_024426.6(WT1):c.1154G>A (p.Arg385Gln)	rs147241955	0.00003
NM_024426.6(WT1):c.695G>C (p.Ser232Thr)	rs761913397

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