ClinVar Miner

List of variants reported as benign for hypersensitivity reaction disease

Included ClinVar conditions (29):
Minimum submission review status: Collection method:
Minimum conflict level:
ClinVar version:
Total variants: 205
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HGVS dbSNP gnomAD frequency
NM_000639.3(FASLG):c.452-28T>C rs2639653 0.99043
NM_006254.4(PRKCD):c.1857T>C (p.Pro619=) rs900495 0.94337
NM_006254.4(PRKCD):c.1782C>G (p.Thr594=) rs1075865 0.93819
NM_006254.4(PRKCD):c.1441C>T (p.Leu481=) rs2306574 0.75510
NM_006254.4(PRKCD):c.1743+29T>G rs7630600 0.74353
NM_000043.6(FAS):c.642T>C (p.Thr214=) rs2234978 0.72086
NM_001372051.1(CASP8):c.1305-19A>G rs3769818 0.71850
NM_006254.4(PRKCD):c.115+21C>G rs2306571 0.65337
NM_001228.5(CASP8):c.-26-8189A>G rs3769823 0.64497
NM_001372051.1(CASP8):c.*122G>C rs3185378 0.55328
NC_000010.11:g.88990206A>G rs1800682 0.54268
NC_000001.11:g.172658358C>T rs763110 0.49239
NM_032977.4(CASP10):c.177A>G (p.Ser59=) rs3900115 0.49172
NM_032977.4(CASP10):c.1564T>A (p.Leu522Ile) rs13006529 0.42733
NM_005214.5(CTLA4):c.49A>G (p.Thr17Ala) rs231775 0.39951
NM_005214.5(CTLA4):c.*1148+236G>A rs3087243 0.36123
NM_001372051.1(CASP8):c.*845T>A rs13113 0.33069
NM_006254.4(PRKCD):c.1119G>A (p.Glu373=) rs2230494 0.29106
NM_000043.6(FAS):c.*1084C>T rs1468063 0.16498
NC_000002.12:g.203866796C>T rs16840252 0.16493
NM_001372051.1(CASP8):c.*83G>A rs17860428 0.13714
NM_001372051.1(CASP8):c.*175C>T rs2141331 0.12768
NM_032977.3(CASP10):c.-206C>T rs16836789 0.12450
NM_006254.4(PRKCD):c.180T>C (p.Asp60=) rs2230493 0.12323
NM_032977.4(CASP10):c.*285G>A rs3851974 0.11086
NM_032977.4(CASP10):c.*277G>A rs3931696 0.11064
NM_006254.4(PRKCD):c.1260+19G>A rs41275531 0.10858
NM_001372051.1(CASP8):c.*464T>C rs1045494 0.09887
NM_001372051.1(CASP8):c.960G>A (p.Lys320=) rs1045487 0.09873
NM_000043.6(FAS):c.*565A>T rs1051070 0.07031
NM_032977.4(CASP10):c.923-3C>T rs6753900 0.06908
NC_000002.12:g.203867624C>T rs5742909 0.06759
NM_032977.4(CASP10):c.*1920G>C rs11885191 0.06626
NM_032977.3(CASP10):c.-360T>C rs41429849 0.06590
NM_032977.4(CASP10):c.*2757A>G rs13414860 0.06432
NM_001372051.1(CASP8):c.*99G>A rs13425383 0.05700
NM_000639.3(FASLG):c.147G>A (p.Pro49=) rs61756244 0.05080
NM_032977.4(CASP10):c.1228G>A (p.Val410Ile) rs13010627 0.04350
NM_000043.6(FAS):c.46G>A (p.Ala16Thr) rs3218619 0.03995
NM_000043.6(FAS):c.222A>G (p.Thr74=) rs2229521 0.03925
NM_000043.6(FAS):c.*765T>C rs9658776 0.03922
NM_001141945.3(ACTA2):c.-24+157C>T rs2274355 0.03855
NM_001372051.1(CASP8):c.*429A>G rs17860433 0.03449
NM_032977.4(CASP10):c.*815C>T rs17860409 0.03348
NM_032977.4(CASP10):c.685-20C>T rs17860401 0.03338
NM_006254.4(PRKCD):c.1926G>A (p.Ala642=) rs56338517 0.03080
NM_014009.4(FOXP3):c.543C>T (p.Ser181=) rs2232367 0.03006
NM_032977.4(CASP10):c.1337A>G (p.Tyr446Cys) rs17860405 0.02926
NM_000043.6(FAS):c.-34A>G rs5030766 0.02841
NM_001372051.1(CASP8):c.*411G>C rs17860432 0.02398
NM_000043.6(FAS):c.*142A>G rs9658774 0.02166
NM_000043.6(FAS):c.141G>A (p.Gln47=) rs3218621 0.02156
NM_014009.4(FOXP3):c.648-20G>A rs2232368 0.01436
NM_032977.4(CASP10):c.*367G>C rs41365346 0.01382
NM_000043.6(FAS):c.505+16C>T rs3218620 0.01048
NM_001372051.1(CASP8):c.*60C>T rs13425113 0.00993
NM_000043.6(FAS):c.365C>T (p.Thr122Ile) rs3218614 0.00774
NM_032977.4(CASP10):c.*3513A>G rs6752492 0.00762
NM_005214.5(CTLA4):c.75G>C (p.Leu25=) rs16840275 0.00761
NM_006254.4(PRKCD):c.741C>T (p.Cys247=) rs55709737 0.00741
NM_000043.6(FAS):c.183G>A (p.Lys61=) rs3218613 0.00606
NM_032977.4(CASP10):c.*2689A>G rs41447745 0.00601
NM_001228.5(CASP8):c.-143T>G rs34609836 0.00568
NM_006254.4(PRKCD):c.214G>C (p.Val72Leu) rs151061939 0.00535
NM_032977.4(CASP10):c.*2831C>T rs151162733 0.00535
NM_000043.6(FAS):c.369G>A (p.Gln123=) rs28362318 0.00529
NM_032977.4(CASP10):c.*2289A>C rs41369551 0.00488
NM_032977.4(CASP10):c.*1471G>A rs192319559 0.00466
NM_032977.4(CASP10):c.*665G>A rs142072849 0.00456
NM_032977.4(CASP10):c.*77T>G rs191438878 0.00455
NM_032977.4(CASP10):c.1068G>T (p.Leu356=) rs111489269 0.00455
NM_006254.4(PRKCD):c.1554+8G>A rs141412493 0.00429
NM_001372051.1(CASP8):c.306-1918T>C rs11897628 0.00421
NM_032977.4(CASP10):c.*3137G>C rs41522046 0.00417
NM_032977.4(CASP10):c.*2618G>A rs41431151 0.00382
NM_000639.3(FASLG):c.*606T>A rs74124375 0.00364
NM_032977.4(CASP10):c.*1043C>T rs553212718 0.00334
NM_000043.6(FAS):c.550A>G (p.Ile184Val) rs28362322 0.00324
NM_001372051.1(CASP8):c.339C>T (p.Ser113=) rs17860422 0.00309
NM_032977.4(CASP10):c.*1593T>C rs564618271 0.00307
NM_032977.4(CASP10):c.1296C>T (p.Ala432=) rs41331850 0.00298
NM_032977.4(CASP10):c.1415+18T>A rs111608359 0.00274
NM_006254.4(PRKCD):c.1260+6C>T rs180706867 0.00270
NM_032977.4(CASP10):c.*1793C>A rs114760847 0.00258
NM_032977.4(CASP10):c.*1955G>A rs139807893 0.00249
NM_032977.4(CASP10):c.*3071G>A rs41339144 0.00247
NM_014009.4(FOXP3):c.324G>A (p.Thr108=) rs111856931 0.00245
NM_032977.4(CASP10):c.534A>C (p.Val178=) rs146233833 0.00226
NM_000639.3(FASLG):c.451+7A>G rs201525996 0.00210
NM_014009.4(FOXP3):c.648-13T>A rs190739204 0.00201
NM_032977.4(CASP10):c.*1688A>G rs41515650 0.00191
NM_014009.4(FOXP3):c.210+16C>T rs372471440 0.00165
NM_000639.3(FASLG):c.*817A>G rs45442301 0.00162
NM_014009.4(FOXP3):c.176C>G (p.Ser59Cys) rs199917616 0.00151
NM_000639.3(FASLG):c.*406G>T rs138658215 0.00150
NM_000043.6(FAS):c.33T>A (p.Val11=) rs113022949 0.00135
NM_032977.4(CASP10):c.722-16G>T rs41500646 0.00121
NM_000043.6(FAS):c.*638T>C rs192032778 0.00117
NM_006254.4(PRKCD):c.603C>T (p.Ile201=) rs75794462 0.00108
NM_005214.5(CTLA4):c.*375G>A rs13384548 0.00105
NM_006254.4(PRKCD):c.1415+19C>T rs202080219 0.00105
NM_032977.4(CASP10):c.1502C>T (p.Pro501Leu) rs148939095 0.00091
NM_000043.6(FAS):c.103T>C (p.Leu35=) rs9333296 0.00083
NM_001372051.1(CASP8):c.1304+12C>T rs375465590 0.00081
NM_006254.4(PRKCD):c.315+9C>A rs200076653 0.00078
NM_000043.6(FAS):c.*1333G>T rs9658779 0.00071
NM_032977.4(CASP10):c.*1914C>T rs185318287 0.00070
NM_006254.4(PRKCD):c.1043A>G (p.Asn348Ser) rs33911937 0.00064
NM_000043.6(FAS):c.*1203G>A rs190060976 0.00062
NM_006254.4(PRKCD):c.539+13C>T rs200442846 0.00058
NM_032977.4(CASP10):c.1415+16T>C rs201336330 0.00058
NM_032977.4(CASP10):c.347+8C>T rs140246829 0.00056
NM_014009.4(FOXP3):c.155G>T (p.Gly52Val) rs17847095 0.00055
NM_000639.3(FASLG):c.108G>A (p.Val36=) rs140595317 0.00054
NM_001372051.1(CASP8):c.789A>G (p.Thr263=) rs35142591 0.00051
NM_000639.3(FASLG):c.*754G>A rs55779656 0.00049
NM_000043.6(FAS):c.505+14T>G rs76988052 0.00038
NM_000639.3(FASLG):c.395-15C>G rs370579312 0.00038
NM_006254.4(PRKCD):c.1743+8C>T rs182290450 0.00038
NM_000639.3(FASLG):c.174G>A (p.Pro58=) rs372411796 0.00034
NM_000639.3(FASLG):c.364C>A (p.His122Asn) rs140406512 0.00034
NM_032977.4(CASP10):c.-8+5G>A rs781551128 0.00034
NM_000639.3(FASLG):c.280T>G (p.Leu94Val) rs56302117 0.00033
NM_032977.4(CASP10):c.1202_1208del (p.Cys401fs) rs747900630 0.00033
NM_000639.3(FASLG):c.*725A>G rs542205727 0.00030
NM_000639.3(FASLG):c.259T>C (p.Phe87Leu) rs530390117 0.00030
NM_000043.6(FAS):c.578A>G (p.Lys193Arg) rs150489856 0.00026
NM_000639.3(FASLG):c.360G>C (p.Gln120His) rs372615226 0.00026
NM_014009.4(FOXP3):c.1044+17G>A rs11465478 0.00026
NM_032977.4(CASP10):c.*739T>C rs559831804 0.00024
NM_000043.6(FAS):c.*582T>G rs542335688 0.00023
NM_014009.4(FOXP3):c.340C>T (p.Arg114Trp) rs200554980 0.00023
NM_032977.4(CASP10):c.1347T>C (p.Phe449=) rs147814983 0.00021
NM_000043.6(FAS):c.*84G>A rs754986111 0.00020
NM_032977.4(CASP10):c.930G>T (p.Leu310=) rs149096064 0.00020
NM_014009.4(FOXP3):c.874G>A (p.Val292Ile) rs74162067 0.00019
NM_014009.4(FOXP3):c.455-6C>T rs373767482 0.00018
NM_000639.3(FASLG):c.*3G>T rs200021473 0.00016
NM_014009.4(FOXP3):c.112G>T (p.Ala38Ser) rs782239006 0.00014
NM_032977.4(CASP10):c.*230G>A rs565567149 0.00014
NM_014009.4(FOXP3):c.249G>C (p.Gly83=) rs782210800 0.00013
NM_032977.4(CASP10):c.1415+8C>G rs200638628 0.00013
NM_032977.4(CASP10):c.666A>G (p.Thr222=) rs116125703 0.00013
NM_014009.4(FOXP3):c.1278C>A (p.Asn426Lys) rs369332983 0.00011
NM_014009.4(FOXP3):c.551C>T (p.Ser184Leu) rs140222626 0.00011
NM_000043.6(FAS):c.*853C>T rs770098016 0.00010
NM_014009.4(FOXP3):c.624C>T (p.Phe208=) rs148215677 0.00010
NM_000639.3(FASLG):c.177G>A (p.Pro59=) rs559795993 0.00009
NM_006254.4(PRKCD):c.1299G>A (p.Gly433=) rs200890839 0.00008
NM_014009.4(FOXP3):c.984G>A (p.Met328Ile) rs367860281 0.00008
NM_000043.6(FAS):c.*174A>G rs776971935 0.00007
NM_014009.4(FOXP3):c.1221C>T (p.Thr407=) rs373302430 0.00007
NM_014009.4(FOXP3):c.361C>T (p.His121Tyr) rs782640594 0.00007
NM_014009.4(FOXP3):c.659C>T (p.Ala220Val) rs2232369 0.00007
NM_014009.4(FOXP3):c.1147-13C>T rs782632308 0.00006
NM_014009.4(FOXP3):c.1241G>A (p.Arg414His) rs782786757 0.00006
NM_014009.4(FOXP3):c.1149C>T (p.Asn383=) rs782267196 0.00005
NM_014009.4(FOXP3):c.873C>T (p.Val291=) rs782371089 0.00005
NM_006254.4(PRKCD):c.115+14C>G rs781949983 0.00004
NM_032977.4(CASP10):c.20A>G (p.His7Arg) rs200935960 0.00004
NM_014009.4(FOXP3):c.1051C>T (p.Leu351=) rs782127412 0.00003
NM_014009.4(FOXP3):c.495G>A (p.Pro165=) rs781920028 0.00003
NM_014009.4(FOXP3):c.735+14G>A rs782539969 0.00003
NM_032977.4(CASP10):c.*846A>G rs41529249 0.00003
NM_014009.4(FOXP3):c.116G>A (p.Arg39Gln) rs782639786 0.00002
NM_014009.4(FOXP3):c.352C>G (p.Leu118Val) rs1373580534 0.00002
NM_014009.4(FOXP3):c.736-14G>A rs76798919 0.00002
NM_000043.6(FAS):c.30+12C>T rs558072404 0.00001
NM_000043.6(FAS):c.78A>G (p.Gln26=) rs746017530 0.00001
NM_000639.3(FASLG):c.451+8T>A rs372021169 0.00001
NM_014009.4(FOXP3):c.200C>T (p.Ser67Leu) rs1382549860 0.00001
NM_014009.4(FOXP3):c.625G>A (p.Glu209Lys) rs143048239 0.00001
NM_014009.4(FOXP3):c.959C>A (p.Thr320Lys) rs781881326 0.00001
NM_032977.4(CASP10):c.*3019C>T rs548104022 0.00001
NM_032977.4(CASP10):c.49A>G (p.Lys17Glu) rs552561721 0.00001
NM_032977.4(CASP10):c.923-13T>G rs776612061 0.00001
NM_000043.6(FAS):c.30+19G>A rs202165529
NM_000043.6(FAS):c.444-5del rs751798922
NM_000043.6(FAS):c.444-5dup rs751798922
NM_000639.3(FASLG):c.*601GT[13] rs10640513
NM_000639.3(FASLG):c.*601GT[17] rs10640513
NM_000639.3(FASLG):c.394+13dup
NM_001372051.1(CASP8):c.*927AT[6] rs397897264
NM_001372051.1(CASP8):c.853G>C (p.Asp285His) rs1045485
NM_006254.4(PRKCD):c.376+16G>T
NM_006254.4(PRKCD):c.658-9del
NM_006254.4(PRKCD):c.912A>G (p.Ser304=) rs529176751
NM_014009.4(FOXP3):c.1045-11C>G rs74162068
NM_014009.4(FOXP3):c.1147-12G>C
NM_014009.4(FOXP3):c.131C>G (p.Thr44Ser)
NM_014009.4(FOXP3):c.168CTC[1] (p.Ser60del) rs781861708
NM_014009.4(FOXP3):c.316-3del rs782086170
NM_014009.4(FOXP3):c.336C>T (p.His112=) rs143632471
NM_014009.4(FOXP3):c.543-3dup
NM_014009.4(FOXP3):c.59C>T (p.Pro20Leu) rs2066089076
NM_014009.4(FOXP3):c.826G>A (p.Asp276Asn)
NM_014009.4(FOXP3):c.968-13del
NM_032977.4(CASP10):c.*1520C>T rs41331447
NM_032977.4(CASP10):c.*1982del rs111572089
NM_032977.4(CASP10):c.1415+18del
NM_032977.4(CASP10):c.1415+18dup rs749295497
NM_032977.4(CASP10):c.174C>T (p.Ala58=) rs114625983
NM_032977.4(CASP10):c.347+9G>T rs7608787
NM_032977.4(CASP10):c.348-16dup rs771877930
NM_032977.4(CASP10):c.923-12G>T rs201904750

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