ClinVar Miner

List of variants in gene GPC3 reported as likely benign for Wilms tumor

Included ClinVar conditions (16):
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:
Total variants: 297
Download table as spreadsheet
HGVS dbSNP gnomAD frequency
NM_004484.4(GPC3):c.1032+9C>T rs200782847 0.00069
NM_004484.4(GPC3):c.1713G>A (p.Ser571=) rs149209315 0.00024
NM_004484.4(GPC3):c.1232G>T (p.Ser411Ile) rs139206747 0.00010
NM_004484.4(GPC3):c.516C>T (p.Asp172=) rs369607601 0.00010
NM_004484.4(GPC3):c.93G>A (p.Pro31=) rs781232455 0.00007
NM_004484.4(GPC3):c.672A>G (p.Gln224=) rs373406834 0.00006
NM_004484.4(GPC3):c.1078G>T (p.Ala360Ser) rs779187915 0.00005
NM_004484.4(GPC3):c.1494C>T (p.Cys498=) rs753210097 0.00005
NM_004484.4(GPC3):c.1263T>G (p.Leu421=) rs1474137107 0.00004
NM_004484.4(GPC3):c.1601A>G (p.Asp534Gly) rs755823884 0.00004
NM_004484.4(GPC3):c.1605G>A (p.Ala535=) rs767097459 0.00004
NM_004484.4(GPC3):c.414T>C (p.Thr138=) rs1048793393 0.00004
NM_004484.4(GPC3):c.648G>C (p.Met216Ile) rs752516966 0.00004
NM_004484.4(GPC3):c.972T>C (p.Phe324=) rs183678432 0.00004
NM_004484.4(GPC3):c.1136A>G (p.Glu379Gly) rs756384130 0.00003
NM_004484.4(GPC3):c.1166+16T>C rs1375568930 0.00003
NM_004484.4(GPC3):c.1561C>T (p.Arg521Cys) rs759543703 0.00003
NM_004484.4(GPC3):c.297G>A (p.Glu99=) rs753227537 0.00003
NM_004484.4(GPC3):c.569C>T (p.Ser190Leu) rs780667597 0.00003
NM_004484.4(GPC3):c.608G>A (p.Arg203His) rs375160737 0.00003
NM_004484.4(GPC3):c.983A>G (p.His328Arg) rs761141186 0.00003
NM_004484.4(GPC3):c.1037G>T (p.Gly346Val) rs373916851 0.00002
NM_004484.4(GPC3):c.1041G>A (p.Lys347=) rs775325256 0.00002
NM_004484.4(GPC3):c.1061A>G (p.Gln354Arg) rs1247273709 0.00002
NM_004484.4(GPC3):c.1114G>A (p.Val372Ile) rs140756498 0.00002
NM_004484.4(GPC3):c.1157G>T (p.Ser386Ile) rs773847304 0.00002
NM_004484.4(GPC3):c.1164A>G (p.Arg388=) rs774959145 0.00002
NM_004484.4(GPC3):c.1266C>T (p.Cys422=) rs372843769 0.00002
NM_004484.4(GPC3):c.1323G>A (p.Met441Ile) rs773146310 0.00002
NM_004484.4(GPC3):c.1359G>C (p.Lys453Asn) rs148219256 0.00002
NM_004484.4(GPC3):c.1573+8A>G rs1386448988 0.00002
NM_004484.4(GPC3):c.175+12T>G rs765877667 0.00002
NM_004484.4(GPC3):c.367A>G (p.Lys123Glu) rs755733724 0.00002
NM_004484.4(GPC3):c.369G>C (p.Lys123Asn) rs201942331 0.00002
NM_004484.4(GPC3):c.397A>C (p.Asn133His) rs1339940057 0.00002
NM_004484.4(GPC3):c.39G>T (p.Ala13=) rs1057522079 0.00002
NM_004484.4(GPC3):c.610G>T (p.Asp204Tyr) rs751267769 0.00002
NM_004484.4(GPC3):c.627G>A (p.Gly209=) rs1297328008 0.00002
NM_004484.4(GPC3):c.733C>A (p.His245Asn) rs199778216 0.00002
NM_004484.4(GPC3):c.1031C>T (p.Thr344Ile) rs768328829 0.00001
NM_004484.4(GPC3):c.1033-8T>A rs768284135 0.00001
NM_004484.4(GPC3):c.1050C>T (p.Ala350=) rs910104431 0.00001
NM_004484.4(GPC3):c.1074A>G (p.Arg358=) rs748177539 0.00001
NM_004484.4(GPC3):c.1117T>C (p.Leu373=) rs1158179802 0.00001
NM_004484.4(GPC3):c.1158C>T (p.Ser386=) rs1317567175 0.00001
NM_004484.4(GPC3):c.1167-18G>A rs376180673 0.00001
NM_004484.4(GPC3):c.1178A>C (p.Gln393Pro) rs1313616176 0.00001
NM_004484.4(GPC3):c.1181A>G (p.Lys394Arg) rs764609423 0.00001
NM_004484.4(GPC3):c.1224C>T (p.Tyr408=) rs764743087 0.00001
NM_004484.4(GPC3):c.1247C>T (p.Ala416Val) rs770886523 0.00001
NM_004484.4(GPC3):c.1255G>A (p.Asp419Asn) rs755544588 0.00001
NM_004484.4(GPC3):c.126C>T (p.Phe42=) rs1345541727 0.00001
NM_004484.4(GPC3):c.1292+20A>T rs751617029 0.00001
NM_004484.4(GPC3):c.1293-4A>G rs760507742 0.00001
NM_004484.4(GPC3):c.1293-5T>C rs766154973 0.00001
NM_004484.4(GPC3):c.1296C>T (p.Tyr432=) rs946461494 0.00001
NM_004484.4(GPC3):c.1371A>G (p.Pro457=) rs775401103 0.00001
NM_004484.4(GPC3):c.1404C>T (p.His468=) rs145981282 0.00001
NM_004484.4(GPC3):c.1410C>T (p.Asn470=) rs1176444823 0.00001
NM_004484.4(GPC3):c.1413+8G>A rs2070728404 0.00001
NM_004484.4(GPC3):c.1414-7C>T rs766064951 0.00001
NM_004484.4(GPC3):c.1437C>G (p.Pro479=) rs1337307928 0.00001
NM_004484.4(GPC3):c.1452G>A (p.Leu484=) rs1451331248 0.00001
NM_004484.4(GPC3):c.1536A>C (p.Gly512=) rs1453935606 0.00001
NM_004484.4(GPC3):c.1547T>C (p.Val516Ala) rs763968425 0.00001
NM_004484.4(GPC3):c.1573+15C>G rs1183489326 0.00001
NM_004484.4(GPC3):c.159A>G (p.Pro53=) rs764505002 0.00001
NM_004484.4(GPC3):c.1619A>G (p.Gln540Arg) rs757034991 0.00001
NM_004484.4(GPC3):c.1671C>T (p.Asn557=) rs1487734633 0.00001
NM_004484.4(GPC3):c.1686G>C (p.Leu562=) rs1556111740 0.00001
NM_004484.4(GPC3):c.1698C>T (p.Thr566=) rs201310379 0.00001
NM_004484.4(GPC3):c.192A>T (p.Val64=) rs2076401014 0.00001
NM_004484.4(GPC3):c.259T>C (p.Leu87=) rs1399185241 0.00001
NM_004484.4(GPC3):c.342C>T (p.Ala114=) rs748391795 0.00001
NM_004484.4(GPC3):c.34G>T (p.Val12Leu) rs748152935 0.00001
NM_004484.4(GPC3):c.363T>A (p.His121Gln) rs754433681 0.00001
NM_004484.4(GPC3):c.415C>T (p.Pro139Ser) rs149261557 0.00001
NM_004484.4(GPC3):c.430T>A (p.Phe144Ile) rs1404574866 0.00001
NM_004484.4(GPC3):c.450A>G (p.Thr150=) rs1569426383 0.00001
NM_004484.4(GPC3):c.480C>T (p.Asp160=) rs970592059 0.00001
NM_004484.4(GPC3):c.496A>G (p.Met166Val) rs1556297827 0.00001
NM_004484.4(GPC3):c.543G>A (p.Gln181=) rs1266410074 0.00001
NM_004484.4(GPC3):c.62C>A (p.Pro21Gln) rs745984441 0.00001
NM_004484.4(GPC3):c.696T>C (p.Ala232=) rs2071695506 0.00001
NM_004484.4(GPC3):c.69G>A (p.Gln23=) rs1197283364 0.00001
NM_004484.4(GPC3):c.727A>G (p.Thr243Ala) rs1203561413 0.00001
NM_004484.4(GPC3):c.735C>T (p.His245=) rs776010902 0.00001
NM_004484.4(GPC3):c.747T>C (p.Ser249=) rs1229244439 0.00001
NM_004484.4(GPC3):c.797A>G (p.Gln266Arg) rs765072095 0.00001
NM_004484.4(GPC3):c.802C>T (p.Leu268=) rs754903885 0.00001
NM_004484.4(GPC3):c.918T>C (p.Leu306=) rs753655328 0.00001
NM_004484.4(GPC3):c.954C>T (p.Asn318=) rs2071689255 0.00001
NM_004484.4(GPC3):c.955G>A (p.Val319Ile) rs753020197 0.00001
NM_004484.4(GPC3):c.966T>C (p.Gly322=) rs1211890549 0.00001
NM_004484.4(GPC3):c.1008G>A (p.Lys336=) rs773421934
NM_004484.4(GPC3):c.1011T>C (p.Asn337=) rs2124479734
NM_004484.4(GPC3):c.1023G>A (p.Leu341=) rs1603240427
NM_004484.4(GPC3):c.1032+10_1032+11delinsTT rs1556297529
NM_004484.4(GPC3):c.1032+8C>G rs2124479685
NM_004484.4(GPC3):c.1032+9C>G rs200782847
NM_004484.4(GPC3):c.1033-10C>A
NM_004484.4(GPC3):c.1033-17T>A
NM_004484.4(GPC3):c.1033-20T>A
NM_004484.4(GPC3):c.1033-20T>C
NM_004484.4(GPC3):c.1033-9dup rs1261922262
NM_004484.4(GPC3):c.1064G>A (p.Arg355His) rs1556271627
NM_004484.4(GPC3):c.1098C>T (p.Leu366=) rs747190100
NM_004484.4(GPC3):c.1113A>G (p.Lys371=)
NM_004484.4(GPC3):c.1130A>G (p.His377Arg) rs1060502172
NM_004484.4(GPC3):c.1143A>G (p.Glu381=)
NM_004484.4(GPC3):c.1155C>T (p.Ser385=)
NM_004484.4(GPC3):c.1166+15T>C
NM_004484.4(GPC3):c.1166+19C>G rs2124437379
NM_004484.4(GPC3):c.1166+19C>T
NM_004484.4(GPC3):c.1166+20T>C
NM_004484.4(GPC3):c.1166+8G>A rs2124437393
NM_004484.4(GPC3):c.1166+8G>T rs2124437393
NM_004484.4(GPC3):c.1167-12T>C rs2124430999
NM_004484.4(GPC3):c.1167-13G>A
NM_004484.4(GPC3):c.1167-13G>C
NM_004484.4(GPC3):c.1167-15T>C rs1603226545
NM_004484.4(GPC3):c.1167-20A>G rs966564128
NM_004484.4(GPC3):c.1170A>T (p.Glu390Asp) rs752110529
NM_004484.4(GPC3):c.1188G>A (p.Lys396=)
NM_004484.4(GPC3):c.1200C>T (p.Ser400=) rs1481312903
NM_004484.4(GPC3):c.1209T>C (p.Ser403=) rs1456710707
NM_004484.4(GPC3):c.120C>G (p.Ser40=) rs1220902363
NM_004484.4(GPC3):c.1212T>C (p.Ala404=) rs1556263726
NM_004484.4(GPC3):c.1233C>T (p.Ser411=)
NM_004484.4(GPC3):c.1235A>G (p.His412Arg) rs2071073427
NM_004484.4(GPC3):c.1239C>T (p.Ser413=) rs2124430790
NM_004484.4(GPC3):c.1251A>G (p.Glu417=) rs2124430772
NM_004484.4(GPC3):c.1259C>G (p.Thr420Ser) rs377381100
NM_004484.4(GPC3):c.1281A>G (p.Glu427=) rs2124430685
NM_004484.4(GPC3):c.1284C>T (p.Leu428=) rs2124430679
NM_004484.4(GPC3):c.1292+17G>T
NM_004484.4(GPC3):c.1292+18T>A
NM_004484.4(GPC3):c.1292+19T>C rs2124430634
NM_004484.4(GPC3):c.1293-11C>T rs2124401934
NM_004484.4(GPC3):c.1293-15C>T rs2124401937
NM_004484.4(GPC3):c.1293-8C>G rs2124401928
NM_004484.4(GPC3):c.1293-8C>T rs2124401928
NM_004484.4(GPC3):c.12C>A (p.Thr4=)
NM_004484.4(GPC3):c.12C>T (p.Thr4=)
NM_004484.4(GPC3):c.1314G>A (p.Arg438=) rs2124401881
NM_004484.4(GPC3):c.1377C>T (p.Val459=)
NM_004484.4(GPC3):c.1401G>A (p.Lys467=)
NM_004484.4(GPC3):c.1413+11T>C
NM_004484.4(GPC3):c.1413+11del
NM_004484.4(GPC3):c.1413+12A>G rs2124401731
NM_004484.4(GPC3):c.1413+13del
NM_004484.4(GPC3):c.1413+18A>G
NM_004484.4(GPC3):c.1414-16G>T rs753432691
NM_004484.4(GPC3):c.1414-9T>C rs2124331197
NM_004484.4(GPC3):c.1419G>T (p.Leu473=) rs2069919503
NM_004484.4(GPC3):c.141C>T (p.Pro47=)
NM_004484.4(GPC3):c.1425C>G (p.Thr475=)
NM_004484.4(GPC3):c.1425C>T (p.Thr475=) rs760974627
NM_004484.4(GPC3):c.1426A>T (p.Met476Leu) rs200265913
NM_004484.4(GPC3):c.1440A>G (p.Lys480=)
NM_004484.4(GPC3):c.1461C>T (p.Asn487=) rs1464494006
NM_004484.4(GPC3):c.1467T>C (p.Asp489=) rs2124331046
NM_004484.4(GPC3):c.1476G>A (p.Gly492=) rs2069918045
NM_004484.4(GPC3):c.1488A>G (p.Gly496=)
NM_004484.4(GPC3):c.1518T>A (p.Ile506=) rs2124330920
NM_004484.4(GPC3):c.1524C>T (p.Gly508=)
NM_004484.4(GPC3):c.1560C>A (p.Leu520=)
NM_004484.4(GPC3):c.1566C>T (p.Phe522=)
NM_004484.4(GPC3):c.1573+10T>A rs878854706
NM_004484.4(GPC3):c.1573+15C>T
NM_004484.4(GPC3):c.1573+20C>G
NM_004484.4(GPC3):c.1573+9T>G rs1387529611
NM_004484.4(GPC3):c.1574-9_1574-7dup
NM_004484.4(GPC3):c.1578G>A (p.Leu526=)
NM_004484.4(GPC3):c.1604C>G (p.Ala535Gly) rs750138489
NM_004484.4(GPC3):c.1605G>T (p.Ala535=) rs767097459
NM_004484.4(GPC3):c.1647A>T (p.Ile549=) rs2069289280
NM_004484.4(GPC3):c.1662C>T (p.Asn554=) rs2124257485
NM_004484.4(GPC3):c.1665C>G (p.Leu555=) rs1248944051
NM_004484.4(GPC3):c.1665C>T (p.Leu555=) rs1248944051
NM_004484.4(GPC3):c.1677T>C (p.His559=)
NM_004484.4(GPC3):c.1701C>T (p.Ser567=)
NM_004484.4(GPC3):c.1702A>G (p.Met568Val) rs1277140205
NM_004484.4(GPC3):c.1719G>A (p.Val573=)
NM_004484.4(GPC3):c.1724T>G (p.Phe575Cys) rs981077333
NM_004484.4(GPC3):c.1725C>T (p.Phe575=) rs925042479
NM_004484.4(GPC3):c.1731C>T (p.Phe577=)
NM_004484.4(GPC3):c.1737G>A (p.Val579=) rs1556111517
NM_004484.4(GPC3):c.1737G>C (p.Val579=)
NM_004484.4(GPC3):c.175+11G>A
NM_004484.4(GPC3):c.175+7A>C
NM_004484.4(GPC3):c.175+7_175+9del rs2076561928
NM_004484.4(GPC3):c.175+8G>C rs2124655623
NM_004484.4(GPC3):c.175+9G>C rs776234359
NM_004484.4(GPC3):c.176-13T>G
NM_004484.4(GPC3):c.176-14C>A
NM_004484.4(GPC3):c.176-14C>T
NM_004484.4(GPC3):c.176-20G>A
NM_004484.4(GPC3):c.176-8T>C
NM_004484.4(GPC3):c.180A>C (p.Ser60=) rs2124634903
NM_004484.4(GPC3):c.184T>C (p.Leu62=)
NM_004484.4(GPC3):c.192A>G (p.Val64=) rs2076401014
NM_004484.4(GPC3):c.210A>T (p.Pro70=) rs2124634878
NM_004484.4(GPC3):c.219C>T (p.Cys73=) rs2076400785
NM_004484.4(GPC3):c.21C>T (p.Thr7=) rs192833218
NM_004484.4(GPC3):c.222A>C (p.Ser74=) rs1556359362
NM_004484.4(GPC3):c.240A>G (p.Lys80=) rs2076400678
NM_004484.4(GPC3):c.246A>G (p.Gln82=) rs2124634833
NM_004484.4(GPC3):c.249A>G (p.Leu83=) rs755510528
NM_004484.4(GPC3):c.24G>A (p.Ala8=)
NM_004484.4(GPC3):c.255A>C (p.Ala85=)
NM_004484.4(GPC3):c.258A>G (p.Arg86=)
NM_004484.4(GPC3):c.276G>C (p.Leu92=) rs2124634777
NM_004484.4(GPC3):c.279T>C (p.Leu93=) rs2124634772
NM_004484.4(GPC3):c.300C>T (p.Leu100=)
NM_004484.4(GPC3):c.307T>C (p.Leu103=)
NM_004484.4(GPC3):c.309A>G (p.Leu103=) rs2124634737
NM_004484.4(GPC3):c.318G>A (p.Gln106=)
NM_004484.4(GPC3):c.337+10G>A rs2124634706
NM_004484.4(GPC3):c.337+12G>A rs2124634702
NM_004484.4(GPC3):c.337+13G>A rs1268216012
NM_004484.4(GPC3):c.337+14A>G
NM_004484.4(GPC3):c.337+8C>G rs1556359306
NM_004484.4(GPC3):c.337+9T>C rs866252085
NM_004484.4(GPC3):c.338-20dup rs370737647
NM_004484.4(GPC3):c.338-4A>T rs1490568896
NM_004484.4(GPC3):c.338-5del rs370737647
NM_004484.4(GPC3):c.338-6_338-5dup rs370737647
NM_004484.4(GPC3):c.338-7_338-5del rs370737647
NM_004484.4(GPC3):c.351T>C (p.Ile117=) rs1603240797
NM_004484.4(GPC3):c.384C>A (p.Ala128=) rs761541528
NM_004484.4(GPC3):c.399C>T (p.Asn133=) rs2124480857
NM_004484.4(GPC3):c.39G>A (p.Ala13=)
NM_004484.4(GPC3):c.417A>C (p.Pro139=) rs2071702267
NM_004484.4(GPC3):c.420A>G (p.Gln140=) rs2124480838
NM_004484.4(GPC3):c.429G>A (p.Glu143=)
NM_004484.4(GPC3):c.456G>A (p.Val152=) rs1363884283
NM_004484.4(GPC3):c.45G>C (p.Leu15=)
NM_004484.4(GPC3):c.462C>T (p.Leu154=)
NM_004484.4(GPC3):c.465C>T (p.Tyr155=) rs2124480772
NM_004484.4(GPC3):c.486T>C (p.Asn162=)
NM_004484.4(GPC3):c.489A>C (p.Val163=) rs2124480706
NM_004484.4(GPC3):c.48C>T (p.Leu16=)
NM_004484.4(GPC3):c.495C>T (p.Asp165=)
NM_004484.4(GPC3):c.504T>C (p.Asn168=)
NM_004484.4(GPC3):c.507A>G (p.Glu169=)
NM_004484.4(GPC3):c.517A>G (p.Ser173Gly) rs2071700126
NM_004484.4(GPC3):c.522G>A (p.Leu174=) rs2124480642
NM_004484.4(GPC3):c.525T>C (p.Phe175=) rs2124480639
NM_004484.4(GPC3):c.531C>T (p.Val177=) rs1603240705
NM_004484.4(GPC3):c.558C>A (p.Gly186=) rs2124480590
NM_004484.4(GPC3):c.573C>T (p.Ala191=) rs2124480540
NM_004484.4(GPC3):c.585T>C (p.Asn195=) rs2124480509
NM_004484.4(GPC3):c.588G>A (p.Glu196=) rs2124480503
NM_004484.4(GPC3):c.606A>G (p.Arg202=) rs1603240654
NM_004484.4(GPC3):c.609T>G (p.Arg203=)
NM_004484.4(GPC3):c.60C>T (p.Phe20=)
NM_004484.4(GPC3):c.624T>C (p.Phe208=) rs140848049
NM_004484.4(GPC3):c.633C>T (p.Phe211=) rs2071696918
NM_004484.4(GPC3):c.63G>A (p.Pro21=) rs2076563636
NM_004484.4(GPC3):c.63G>T (p.Pro21=) rs2076563636
NM_004484.4(GPC3):c.651C>T (p.Thr217=)
NM_004484.4(GPC3):c.66A>G (p.Gly22=) rs2124655806
NM_004484.4(GPC3):c.687C>T (p.Phe229=) rs2124480310
NM_004484.4(GPC3):c.717G>A (p.Val239=) rs2124480274
NM_004484.4(GPC3):c.720C>T (p.Ile240=) rs1463771487
NM_004484.4(GPC3):c.72G>A (p.Ala24=) rs1281815760
NM_004484.4(GPC3):c.737_738delinsCT (p.Leu246Pro) rs1603240567
NM_004484.4(GPC3):c.750G>A (p.Lys250=)
NM_004484.4(GPC3):c.761G>A (p.Arg254Gln) rs756844729
NM_004484.4(GPC3):c.761G>T (p.Arg254Leu) rs756844729
NM_004484.4(GPC3):c.762A>G (p.Arg254=) rs934493521
NM_004484.4(GPC3):c.786C>T (p.Cys262=)
NM_004484.4(GPC3):c.792C>T (p.Tyr264=) rs2124480140
NM_004484.4(GPC3):c.801A>T (p.Gly267=)
NM_004484.4(GPC3):c.805A>T (p.Met269Leu) rs1556297682
NM_004484.4(GPC3):c.826G>T (p.Gly276Cys) rs141100113
NM_004484.4(GPC3):c.840G>C (p.Val280=) rs2071692419
NM_004484.4(GPC3):c.840G>T (p.Val280=)
NM_004484.4(GPC3):c.849A>G (p.Gln283=)
NM_004484.4(GPC3):c.852C>T (p.Gly284=) rs1603240522
NM_004484.4(GPC3):c.873G>A (p.Glu291=) rs2124480012
NM_004484.4(GPC3):c.879C>T (p.Asp293=) rs2124479990
NM_004484.4(GPC3):c.882G>A (p.Lys294=) rs2124479973
NM_004484.4(GPC3):c.906C>G (p.Ser302=) rs747860984
NM_004484.4(GPC3):c.909T>C (p.Leu303=)
NM_004484.4(GPC3):c.90G>A (p.Pro30=) rs2124655746
NM_004484.4(GPC3):c.918T>G (p.Leu306=) rs753655328
NM_004484.4(GPC3):c.942T>C (p.Tyr314=) rs1603240471
NM_004484.4(GPC3):c.958C>T (p.Leu320=) rs372222280
NM_004484.4(GPC3):c.960G>C (p.Leu320=) rs1446548510
NM_004484.4(GPC3):c.960G>T (p.Leu320=) rs1446548510
NM_004484.4(GPC3):c.969C>T (p.Leu323=) rs11539788
NM_004484.4(GPC3):c.978A>C (p.Thr326=) rs2124479792
NM_004484.4(GPC3):c.984T>C (p.His328=)
NM_004484.4(GPC3):c.986A>G (p.Asp329Gly) rs1199305584
NM_004484.4(GPC3):c.990T>C (p.Ser330=) rs2124479772

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