ClinVar Miner

List of variants in gene combination LOC107982234, WT1 reported as benign for Wilms tumor

Included ClinVar conditions (21):

Aniridia 1; Drash syndrome; Frasier syndrome; Meacham syndrome; Mesothelioma, malignant; Nephrotic syndrome, type 4; Wilms tumor 1; 11p partial monosomy syndrome
Autosomal dominant nonsyndromic hearing loss 27; Wilms tumor 6; Fibromatosis, gingival, 5
Beckwith-Wiedemann syndrome; Wilms tumor 1; Silver-Russell syndrome 1; Silver-Russell syndrome 3
Childhood kidney Wilms tumor
Drash syndrome; Frasier syndrome; Meacham syndrome; Mesothelioma, malignant; Nephrotic syndrome, type 4; Wilms tumor 1
Drash syndrome; Frasier syndrome; Nephrotic syndrome, type 4; Wilms tumor 1
Drash syndrome; Frasier syndrome; Wilms tumor 1
Drash syndrome; Frasier syndrome; Wilms tumor 1; 11p partial monosomy syndrome
Familial cancer of breast; Breast-ovarian cancer, familial, susceptibility to, 2; Fanconi anemia complementation group D1; Medulloblastoma; Wilms tumor 1; Glioma susceptibility 3; Familial prostate cancer
Familial cancer of breast; Breast-ovarian cancer, familial, susceptibility to, 2; Fanconi anemia complementation group D1; Medulloblastoma; Wilms tumor 1; Pancreatic cancer, susceptibility to, 2; Glioma susceptibility 3; Familial prostate cancer
Familial cancer of breast; Breast-ovarian cancer, familial, susceptibility to, 2; Fanconi anemia complementation group D1; Medulloblastoma; Wilms tumor 1; Prostate cancer; Pancreatic cancer, susceptibility to, 2; Glioma susceptibility 3
Familial cancer of breast; Breast-ovarian cancer, familial, susceptibility to, 2; Fanconi anemia complementation group D1; Medulloblastoma; Wilms tumor 1; Prostate cancer; Pancreatic cancer, susceptibility to, 2; Glioma susceptibility 3; Esophageal atresia/tracheoesophageal fistula
Familial cancer of breast; Breast-ovarian cancer, familial, susceptibility to, 2; Fanconi anemia complementation group D1; Medulloblastoma; Wilms tumor 1; Prostate cancer; Pancreatic cancer, susceptibility to, 2; Glioma susceptibility 3; Melanoma, cutaneous malignant, susceptibility to, 1
Keipert syndrome; Wilms tumor 1; Simpson-Golabi-Behmel syndrome type 1
Nephroblastoma
Nephroblastoma; Familial colorectal cancer type X
Wilms tumor 1
Wilms tumor 1; Simpson-Golabi-Behmel syndrome type 1
Wilms tumor 2
Wilms tumor 5
Wilms tumor 6

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 13

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HGVS	dbSNP	gnomAD frequency
NM_024426.6(WT1):c.213G>T (p.Pro71=)	rs2234582	0.30977
NM_024426.6(WT1):c.345C>T (p.Pro115=)	rs1799925	0.16767
NM_024426.6(WT1):c.609C>T (p.Asn203=)	rs2234583	0.13287
NM_024426.6(WT1):c.662-1928_662-1927del	rs71873106	0.02282
NM_024426.6(WT1):c.181C>A (p.Arg61=)	rs2234581	0.00269
NM_024426.6(WT1):c.123G>C (p.Pro41=)	rs555140661	0.00189
NM_024426.6(WT1):c.309C>A (p.Gly103=)	rs547333427	0.00182
NM_024426.6(WT1):c.375C>T (p.Gly125=)	rs776209354	0.00039
NM_024426.6(WT1):c.216G>T (p.Gln72His)	rs5030135	0.00036
NM_024426.6(WT1):c.193G>A (p.Gly65Arg)	rs374404615	0.00018
NM_024426.6(WT1):c.381C>G (p.Pro127=)	rs771681406	0.00009
NM_024426.6(WT1):c.513C>A (p.Gly171=)	rs536728682	0.00004
NM_024426.6(WT1):c.543C>T (p.Arg181=)	rs369870529

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