List of variants in gene PRKCD reported as likely benign for autoimmune disease

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 215

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HGVS	dbSNP	gnomAD frequency
NM_006254.4(PRKCD):c.603C>T (p.Ile201=)	rs75794462	0.00108
NM_006254.4(PRKCD):c.315+9C>A	rs200076653	0.00078
NM_006254.4(PRKCD):c.1447C>T (p.Arg483Trp)	rs35891605	0.00063
NM_006254.4(PRKCD):c.1705C>T (p.Arg569Cys)	rs141992569	0.00055
NM_006254.4(PRKCD):c.1362C>T (p.Ala454=)	rs41295962	0.00050
NM_006254.4(PRKCD):c.1500C>T (p.Phe500=)	rs149751382	0.00046
NM_006254.4(PRKCD):c.1415+7G>C	rs78905675	0.00043
NM_006254.4(PRKCD):c.68C>T (p.Ala23Val)	rs144572650	0.00041
NM_006254.4(PRKCD):c.787+14C>T	rs376532118	0.00041
NM_006254.4(PRKCD):c.1213G>A (p.Ala405Thr)	rs150331740	0.00040
NM_006254.4(PRKCD):c.1244G>A (p.Cys415Tyr)	rs35181307	0.00036
NM_006254.4(PRKCD):c.1691C>T (p.Thr564Met)	rs146289210	0.00030
NM_006254.4(PRKCD):c.395G>A (p.Arg132His)	rs200939049	0.00029
NM_006254.4(PRKCD):c.948C>T (p.Phe316=)	rs138049008	0.00021
NM_006254.4(PRKCD):c.377-12C>T	rs181439333	0.00019
NM_006254.4(PRKCD):c.658-5_658-2dup	rs782574122	0.00014
NM_006254.4(PRKCD):c.657+15G>A	rs190144895	0.00013
NM_006254.4(PRKCD):c.899G>A (p.Arg300Gln)	rs143488209	0.00012
NM_006254.4(PRKCD):c.1167C>T (p.Asp389=)	rs781931484	0.00011
NM_006254.4(PRKCD):c.1260+7G>A	rs374605708	0.00011
NM_006254.4(PRKCD):c.1554+13C>T	rs551694897	0.00010
NM_006254.4(PRKCD):c.1470C>T (p.Ala490=)	rs781875657	0.00009
NM_006254.4(PRKCD):c.597A>G (p.Lys199=)	rs74558112	0.00009
NM_006254.4(PRKCD):c.1341C>T (p.Leu447=)	rs782659087	0.00007
NM_006254.4(PRKCD):c.1212C>T (p.Ala404=)	rs200149825	0.00006
NM_006254.4(PRKCD):c.315+10G>A	rs782548097	0.00006
NM_006254.4(PRKCD):c.636G>A (p.Ala212=)	rs200410934	0.00006
NM_006254.4(PRKCD):c.945T>C (p.Gly315=)	rs781846856	0.00006
NM_006254.4(PRKCD):c.1293C>T (p.Asn431=)	rs377107086	0.00005
NM_006254.4(PRKCD):c.1692G>A (p.Thr564=)	rs564128768	0.00005
NM_006254.4(PRKCD):c.267G>A (p.Ser89=)	rs782214291	0.00005
NM_006254.4(PRKCD):c.1671C>T (p.Phe557=)	rs147601598	0.00004
NM_006254.4(PRKCD):c.1743+14G>A	rs377684585	0.00004
NM_006254.4(PRKCD):c.174G>A (p.Thr58=)	rs55719519	0.00004
NM_006254.4(PRKCD):c.217C>T (p.Leu73=)	rs782144950	0.00004
NM_006254.4(PRKCD):c.240A>G (p.Pro80=)	rs781855123	0.00004
NM_006254.4(PRKCD):c.579C>T (p.Asn193=)	rs781809625	0.00004
NM_006254.4(PRKCD):c.693C>T (p.His231=)	rs982499152	0.00004
NM_006254.4(PRKCD):c.960C>T (p.Thr320=)	rs143202454	0.00004
NM_006254.4(PRKCD):c.1002C>T (p.Tyr334=)	rs546426559	0.00003
NM_006254.4(PRKCD):c.1156C>T (p.Leu386=)	rs374287889	0.00003
NM_006254.4(PRKCD):c.1554+7C>T	rs370247870	0.00003
NM_006254.4(PRKCD):c.1555-6C>T	rs370593377	0.00003
NM_006254.4(PRKCD):c.1617C>T (p.Tyr539=)	rs375360762	0.00003
NM_006254.4(PRKCD):c.177C>T (p.Phe59=)	rs369306770	0.00003
NM_006254.4(PRKCD):c.405C>T (p.Asp135=)	rs200462015	0.00003
NM_006254.4(PRKCD):c.539+9C>T	rs77075429	0.00003
NM_006254.4(PRKCD):c.571+15A>C	rs781967950	0.00003
NM_006254.4(PRKCD):c.633C>T (p.Thr211=)	rs372745352	0.00003
NM_006254.4(PRKCD):c.63C>T (p.Asp21=)	rs369037399	0.00003
NM_006254.4(PRKCD):c.657+11G>C	rs781971358	0.00003
NM_006254.4(PRKCD):c.915C>T (p.Ala305=)	rs201862364	0.00003
NM_006254.4(PRKCD):c.1086+16C>T	rs373350409	0.00002
NM_006254.4(PRKCD):c.116-17del	rs1553666741	0.00002
NM_006254.4(PRKCD):c.1206A>G (p.Thr402=)	rs74485893	0.00002
NM_006254.4(PRKCD):c.1415+9G>A	rs782267237	0.00002
NM_006254.4(PRKCD):c.1744-7G>A	rs372537259	0.00002
NM_006254.4(PRKCD):c.255C>T (p.Thr85=)	rs782661116	0.00002
NM_006254.4(PRKCD):c.300C>A (p.Gly100=)	rs782734100	0.00002
NM_006254.4(PRKCD):c.315+16G>A	rs782245021	0.00002
NM_006254.4(PRKCD):c.435C>T (p.Arg145=)	rs782029128	0.00002
NM_006254.4(PRKCD):c.539+10G>A	rs1437629018	0.00002
NM_006254.4(PRKCD):c.57C>T (p.Ala19=)	rs377115507	0.00002
NM_006254.4(PRKCD):c.840C>T (p.Cys280=)	rs145324216	0.00002
NM_006254.4(PRKCD):c.864T>C (p.Ala288=)	rs782535622	0.00002
NM_006254.4(PRKCD):c.889-9C>T	rs782612523	0.00002
NM_006254.4(PRKCD):c.986-7C>T	rs781918067	0.00002
NM_006254.4(PRKCD):c.1086+9T>C	rs1486351156	0.00001
NM_006254.4(PRKCD):c.115+9G>A	rs782712864	0.00001
NM_006254.4(PRKCD):c.1176G>A (p.Glu392=)	rs782735766	0.00001
NM_006254.4(PRKCD):c.1260+16G>C	rs1553669090	0.00001
NM_006254.4(PRKCD):c.1353-20T>C	rs1553669452	0.00001
NM_006254.4(PRKCD):c.1554+12C>T	rs201210965	0.00001
NM_006254.4(PRKCD):c.1555-5G>A	rs782208259	0.00001
NM_006254.4(PRKCD):c.1635G>A (p.Gln545=)	rs782122153	0.00001
NM_006254.4(PRKCD):c.1791C>A (p.Ile597=)	rs782819653	0.00001
NM_006254.4(PRKCD):c.21C>T (p.Ile7=)	rs373946656	0.00001
NM_006254.4(PRKCD):c.225G>C (p.Arg75=)	rs781815061	0.00001
NM_006254.4(PRKCD):c.243G>C (p.Val81=)	rs782530190	0.00001
NM_006254.4(PRKCD):c.264G>T (p.Val88=)	rs782433548	0.00001
NM_006254.4(PRKCD):c.276C>T (p.Ala92=)	rs782352450	0.00001
NM_006254.4(PRKCD):c.384A>G (p.Lys128=)	rs1339098133	0.00001
NM_006254.4(PRKCD):c.492C>A (p.Thr164=)	rs187146419	0.00001
NM_006254.4(PRKCD):c.540-18C>T	rs75301864	0.00001
NM_006254.4(PRKCD):c.567C>T (p.Cys189=)	rs150667829	0.00001
NM_006254.4(PRKCD):c.615C>T (p.Ile205=)	rs782677594	0.00001
NM_006254.4(PRKCD):c.678C>T (p.Asn226=)	rs78938657	0.00001
NM_006254.4(PRKCD):c.729C>T (p.Phe243=)	rs782340381	0.00001
NM_006254.4(PRKCD):c.792C>T (p.Cys264=)	rs1553668629	0.00001
NM_006254.4(PRKCD):c.894C>T (p.Ala298=)	rs782394276	0.00001
NM_006254.4(PRKCD):c.985+10G>T	rs781842377	0.00001
NM_006254.4(PRKCD):c.9G>A (p.Pro3=)	rs1354110835	0.00001
NM_006254.4(PRKCD):c.1017G>A (p.Glu339=)
NM_006254.4(PRKCD):c.1029G>A (p.Lys343=)	rs2107276703
NM_006254.4(PRKCD):c.1047C>T (p.Phe349=)
NM_006254.4(PRKCD):c.1053C>T (p.Phe351=)
NM_006254.4(PRKCD):c.105G>A (p.Ala35=)	rs141615361
NM_006254.4(PRKCD):c.105G>T (p.Ala35=)
NM_006254.4(PRKCD):c.1077C>T (p.Ser359=)
NM_006254.4(PRKCD):c.1080C>T (p.Phe360=)
NM_006254.4(PRKCD):c.1086+16_1086+26del
NM_006254.4(PRKCD):c.1086+17G>A
NM_006254.4(PRKCD):c.1086+20C>T
NM_006254.4(PRKCD):c.1087-12T>A	rs2107277347
NM_006254.4(PRKCD):c.1087-15G>A
NM_006254.4(PRKCD):c.1087-15G>T
NM_006254.4(PRKCD):c.1087-16C>T
NM_006254.4(PRKCD):c.1113A>G (p.Arg371=)	rs1257740596
NM_006254.4(PRKCD):c.116-17G>A
NM_006254.4(PRKCD):c.116-7G>C	rs1703347409
NM_006254.4(PRKCD):c.1161C>T (p.Ile387=)	rs782384878
NM_006254.4(PRKCD):c.1164C>T (p.Asp388=)
NM_006254.4(PRKCD):c.1170C>T (p.Asp390=)
NM_006254.4(PRKCD):c.1201C>T (p.Leu401=)	rs2107277772
NM_006254.4(PRKCD):c.1233C>T (p.Thr411=)
NM_006254.4(PRKCD):c.1260+19_1260+34dup
NM_006254.4(PRKCD):c.1261-14C>A
NM_006254.4(PRKCD):c.1269G>A (p.Leu423=)	rs781864780
NM_006254.4(PRKCD):c.1296G>T (p.Gly432=)	rs781784839
NM_006254.4(PRKCD):c.1332C>A (p.Arg444=)
NM_006254.4(PRKCD):c.1353-11C>T
NM_006254.4(PRKCD):c.1353-16C>A
NM_006254.4(PRKCD):c.1353-4C>T	rs782614340
NM_006254.4(PRKCD):c.1353-8_1353-7del	rs2107281087
NM_006254.4(PRKCD):c.1415+11G>C	rs1703747131
NM_006254.4(PRKCD):c.1458C>T (p.His486=)	rs1553670016
NM_006254.4(PRKCD):c.1510C>A (p.Arg504=)
NM_006254.4(PRKCD):c.1515C>T (p.Ala505=)
NM_006254.4(PRKCD):c.1554+14C>G
NM_006254.4(PRKCD):c.1554+8G>C	rs141412493
NM_006254.4(PRKCD):c.1555-12C>A
NM_006254.4(PRKCD):c.1555-14C>G
NM_006254.4(PRKCD):c.1555-17G>A	rs2107285944
NM_006254.4(PRKCD):c.1566C>T (p.Gly522=)
NM_006254.4(PRKCD):c.1569G>A (p.Leu523=)
NM_006254.4(PRKCD):c.1602C>T (p.Phe534=)
NM_006254.4(PRKCD):c.1641C>G (p.Pro547=)
NM_006254.4(PRKCD):c.171G>A (p.Ser57=)
NM_006254.4(PRKCD):c.1743+10CTGGG[5]
NM_006254.4(PRKCD):c.1743+20C>T
NM_006254.4(PRKCD):c.1743+29_1743+38del	rs782221968
NM_006254.4(PRKCD):c.1743+29_1743+43del	rs782585539
NM_006254.4(PRKCD):c.1743+9C>T
NM_006254.4(PRKCD):c.1744-18G>T
NM_006254.4(PRKCD):c.1744-20G>C
NM_006254.4(PRKCD):c.1776A>C (p.Gly592=)
NM_006254.4(PRKCD):c.1788C>T (p.Asn596=)	rs1703861452
NM_006254.4(PRKCD):c.1872+11C>G
NM_006254.4(PRKCD):c.1872+13G>A
NM_006254.4(PRKCD):c.189C>T (p.Ile63=)	rs2107256827
NM_006254.4(PRKCD):c.201C>T (p.Arg67=)
NM_006254.4(PRKCD):c.271C>T (p.Leu91=)	rs79725471
NM_006254.4(PRKCD):c.309G>A (p.Glu103=)
NM_006254.4(PRKCD):c.315+13C>T
NM_006254.4(PRKCD):c.315+17C>T
NM_006254.4(PRKCD):c.315+18C>T
NM_006254.4(PRKCD):c.315+19G>A	rs1703363074
NM_006254.4(PRKCD):c.315+7G>A	rs1559623472
NM_006254.4(PRKCD):c.315+8G>T
NM_006254.4(PRKCD):c.316-7C>T
NM_006254.4(PRKCD):c.420A>G (p.Pro140=)	rs2107262755
NM_006254.4(PRKCD):c.423G>A (p.Thr141=)
NM_006254.4(PRKCD):c.474C>T (p.Asn158=)
NM_006254.4(PRKCD):c.486C>T (p.Ile162=)
NM_006254.4(PRKCD):c.522G>A (p.Val174=)
NM_006254.4(PRKCD):c.531C>T (p.Asp177=)	rs1240610213
NM_006254.4(PRKCD):c.539+16G>A
NM_006254.4(PRKCD):c.540-17T>C
NM_006254.4(PRKCD):c.540-9G>C
NM_006254.4(PRKCD):c.571+15A>G
NM_006254.4(PRKCD):c.571+17G>A
NM_006254.4(PRKCD):c.571+7G>A
NM_006254.4(PRKCD):c.576T>C (p.Cys192=)
NM_006254.4(PRKCD):c.57C>A (p.Ala19=)	rs377115507
NM_006254.4(PRKCD):c.57C>G (p.Ala19=)	rs377115507
NM_006254.4(PRKCD):c.618C>T (p.Gly206=)
NM_006254.4(PRKCD):c.651C>T (p.Asp217=)	rs2107267952
NM_006254.4(PRKCD):c.657+10G>T
NM_006254.4(PRKCD):c.657+14C>T
NM_006254.4(PRKCD):c.657+8T>C
NM_006254.4(PRKCD):c.658-11C>G
NM_006254.4(PRKCD):c.658-14A>G
NM_006254.4(PRKCD):c.658-19G>A
NM_006254.4(PRKCD):c.660C>T (p.Phe220=)
NM_006254.4(PRKCD):c.663G>A (p.Gln221=)
NM_006254.4(PRKCD):c.681C>T (p.Ile227=)
NM_006254.4(PRKCD):c.690G>A (p.Pro230=)	rs55865871
NM_006254.4(PRKCD):c.69G>A (p.Ala23=)
NM_006254.4(PRKCD):c.6G>A (p.Ala2=)	rs1273815639
NM_006254.4(PRKCD):c.750G>A (p.Leu250=)	rs2107269090
NM_006254.4(PRKCD):c.771G>A (p.Gln257=)
NM_006254.4(PRKCD):c.787+15G>A
NM_006254.4(PRKCD):c.787+15G>C	rs369696959
NM_006254.4(PRKCD):c.788-12C>T
NM_006254.4(PRKCD):c.788-18G>A
NM_006254.4(PRKCD):c.788-19C>T
NM_006254.4(PRKCD):c.804G>A (p.Val268=)
NM_006254.4(PRKCD):c.846C>A (p.Ile282=)
NM_006254.4(PRKCD):c.846C>T (p.Ile282=)	rs372028715
NM_006254.4(PRKCD):c.87C>T (p.Ala29=)
NM_006254.4(PRKCD):c.888+12C>T
NM_006254.4(PRKCD):c.888+19G>A
NM_006254.4(PRKCD):c.889-11T>C
NM_006254.4(PRKCD):c.889-20C>A	rs369329996
NM_006254.4(PRKCD):c.889-20C>G	rs369329996
NM_006254.4(PRKCD):c.889-4C>T
NM_006254.4(PRKCD):c.90G>A (p.Val30=)	rs1437451277
NM_006254.4(PRKCD):c.90G>C (p.Val30=)	rs1437451277
NM_006254.4(PRKCD):c.915C>A (p.Ala305=)	rs201862364
NM_006254.4(PRKCD):c.939T>C (p.Tyr313=)
NM_006254.4(PRKCD):c.975G>A (p.Glu325=)
NM_006254.4(PRKCD):c.985+12T>G
NM_006254.4(PRKCD):c.985+18G>A
NM_006254.4(PRKCD):c.985+19C>T
NM_006254.4(PRKCD):c.986-12T>A

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