List of variants reported as uncertain significance for Lynch syndrome 1 by Pathway Genomics

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Total variants: 15

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HGVS	dbSNP	gnomAD frequency
NM_000535.7(PMS2):c.2182A>G (p.Thr728Ala)	rs141893001	0.00203
NM_000535.7(PMS2):c.2012C>T (p.Thr671Met)	rs587780046	0.00017
NM_000535.7(PMS2):c.857A>G (p.Asp286Gly)	rs116788608	0.00011
NM_000179.3(MSH6):c.2384T>C (p.Ile795Thr)	rs202127474	0.00007
NM_000251.3(MSH2):c.2732T>G (p.Leu911Arg)	rs41295182	0.00007
NM_000249.4(MLH1):c.955G>A (p.Glu319Lys)	rs63750796	0.00006
NM_000535.7(PMS2):c.2113G>A (p.Glu705Lys)	rs267608161	0.00003
NM_000249.4(MLH1):c.1327A>C (p.Lys443Gln)	rs34213726	0.00001
NM_000535.7(PMS2):c.452G>A (p.Arg151His)	rs35629870	0.00001
NM_000179.3(MSH6):c.4072A>G (p.Lys1358Glu)	rs199739099
NM_000249.4(MLH1):c.37G>A (p.Glu13Lys)	rs587779008
NM_000251.3(MSH2):c.1030C>A (p.Gln344Lys)	rs63750245
NM_000251.3(MSH2):c.1223A>T (p.Tyr408Phe)	rs63750379
NM_000251.3(MSH2):c.1A>G (p.Met1Val)	rs267607911
NM_000251.3(MSH2):c.2789T>A (p.Ile930Lys)	rs587783054

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