ClinVar Miner

List of variants reported as benign for autosomal dominant keratitis-ichthyosis-hearing loss syndrome

Included ClinVar conditions (4):

Autosomal dominant keratitis-ichthyosis-hearing loss syndrome
Autosomal recessive nonsyndromic hearing loss 1A; Mutilating keratoderma; Ichthyosis, hystrix-like, with hearing loss; Autosomal dominant keratitis-ichthyosis-hearing loss syndrome; Palmoplantar keratoderma-deafness syndrome; Knuckle pads, deafness AND leukonychia syndrome; Autosomal dominant nonsyndromic hearing loss 3A
Autosomal recessive nonsyndromic hearing loss 1A; Mutilating keratoderma; Ichthyosis, hystrix-like, with hearing loss; Autosomal dominant keratitis-ichthyosis-hearing loss syndrome; Palmoplantar keratoderma-deafness syndrome; Knuckle pads, deafness AND leukonychia syndrome; Autosomal dominant nonsyndromic hearing loss 3A; X-linked mixed hearing loss with perilymphatic gusher
Ichthyosis, hystrix-like, with hearing loss; Autosomal dominant keratitis-ichthyosis-hearing loss syndrome

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Total variants: 3

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HGVS	dbSNP	gnomAD frequency
NM_004004.6(GJB2):c.*111C>T	rs7329857	0.06345
NM_004004.6(GJB2):c.457G>A (p.Val153Ile)	rs111033186	0.00414
NM_004004.6(GJB2):c.608T>C (p.Ile203Thr)	rs76838169	0.00191

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