List of variants reported as benign for holoprosencephaly 2

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Total variants: 17

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HGVS	dbSNP	gnomAD frequency
NM_005413.4(SIX3):c.942A>G (p.Ala314=)	rs338074	0.93956
NM_005413.4(SIX3):c.576C>T (p.Arg192=)	rs182881	0.02708
NM_005413.4(SIX3):c.90G>T (p.Ala30=)	rs78018362	0.01666
NM_005413.4(SIX3):c.525G>A (p.Gln175=)	rs116680477	0.00907
NM_005413.4(SIX3):c.109G>T (p.Gly37Cys)	rs199823175	0.00210
NM_005413.4(SIX3):c.720G>T (p.Ala240=)	rs191012035	0.00185
NM_005413.4(SIX3):c.219C>T (p.Pro73=)	rs186163123	0.00105
NM_005413.4(SIX3):c.369G>A (p.Glu123=)	rs200331042	0.00088
NM_005413.4(SIX3):c.348C>T (p.Pro116=)	rs573768953	0.00069
NM_005413.4(SIX3):c.306G>A (p.Thr102=)	rs201451750	0.00024
NM_005413.4(SIX3):c.351G>A (p.Val117=)	rs199742584	0.00009
NM_005413.4(SIX3):c.830C>A (p.Pro277Gln)	rs575632344	0.00007
NM_005413.4(SIX3):c.105G>T (p.Gly35=)	rs779034696	0.00004
NM_005413.4(SIX3):c.187GGC[8] (p.Gly69dup)	rs555285206
NM_005413.4(SIX3):c.58G>T (p.Ala20Ser)	rs200575650
NM_005413.4(SIX3):c.909G>C (p.Pro303=)	rs560888073
SIX3:c.942G>A

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