List of variants in gene VCL reported as uncertain significance by CHEO Genetics Diagnostic Laboratory, Children's Hospital of Eastern Ontario

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 34

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HGVS	dbSNP	gnomAD frequency
NM_014000.3(VCL):c.1294C>G (p.Leu432Val)	rs144146254	0.00025
NM_014000.3(VCL):c.2969C>T (p.Ala990Val)	rs150595117	0.00019
NM_014000.3(VCL):c.590C>T (p.Thr197Ile)	rs189242810	0.00019
NM_014000.3(VCL):c.829C>A (p.Leu277Met)	rs71579353	0.00010
NM_014000.3(VCL):c.1490T>C (p.Ile497Thr)	rs572757800	0.00008
NM_014000.3(VCL):c.1621C>G (p.Leu541Val)	rs370229150	0.00008
NM_014000.3(VCL):c.1743+6A>T	rs370709860	0.00006
NM_014000.3(VCL):c.2467C>T (p.Arg823Trp)	rs779047174	0.00006
NM_014000.3(VCL):c.404T>C (p.Ile135Thr)	rs373744314	0.00006
NM_014000.3(VCL):c.1534C>T (p.Arg512Cys)	rs781079975	0.00004
NM_014000.3(VCL):c.2046A>T (p.Leu682Phe)	rs565398652	0.00004
NM_014000.3(VCL):c.1039C>T (p.Pro347Ser)	rs566961713	0.00003
NM_014000.3(VCL):c.2875A>C (p.Asn959His)	rs758969419	0.00003
NM_014000.3(VCL):c.3267G>C (p.Glu1089Asp)	rs149300310	0.00003
NM_014000.3(VCL):c.1019C>T (p.Ala340Val)	rs374928228	0.00002
NM_014000.3(VCL):c.163G>T (p.Val55Phe)	rs755441334	0.00001
NM_014000.3(VCL):c.1798A>C (p.Ser600Arg)	rs397517236	0.00001
NM_014000.3(VCL):c.2284C>T (p.Arg762Trp)	rs1334643090	0.00001
NM_014000.3(VCL):c.2867T>G (p.Met956Arg)	rs765717598	0.00001
NM_014000.3(VCL):c.313C>T (p.Arg105Ter)	rs397517239	0.00001
NM_014000.3(VCL):c.625A>T (p.Met209Leu)	rs144683137	0.00001
NM_014000.3(VCL):c.140T>G (p.Val47Gly)	rs2136218338
NM_014000.3(VCL):c.1521C>T (p.Pro507=)	rs1564529609
NM_014000.3(VCL):c.169-10delinsTG	rs1554814892
NM_014000.3(VCL):c.1873-7C>T
NM_014000.3(VCL):c.1888G>A (p.Ala630Thr)	rs727503739
NM_014000.3(VCL):c.2143G>A (p.Glu715Lys)	rs1022329091
NM_014000.3(VCL):c.2407G>A (p.Ala803Thr)	rs754294941
NM_014000.3(VCL):c.2539C>G (p.Pro847Ala)
NM_014000.3(VCL):c.3350G>A (p.Arg1117Gln)
NM_014000.3(VCL):c.486G>C (p.Lys162Asn)	rs1841656671
NM_014000.3(VCL):c.500G>A (p.Gly167Glu)	rs1564523552
NM_014000.3(VCL):c.626T>A (p.Met209Lys)	rs751243981
NM_014000.3(VCL):c.963del (p.Leu322fs)	rs1564526327

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