ClinVar Miner

Variants from Laboratory for Molecular Medicine, Partners HealthCare Personalized Medicine

Location: United States — Primary collection method: clinical testing
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign drug response risk factor other not provided total
1751 1343 7479 5941 6991 58 5 1 81 23645

Gene and significance breakdown #

Total genes and gene combinations: 1581
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Gene or gene combination pathogenic likely pathogenic uncertain significance likely benign benign drug response risk factor other not provided total
TTN 5 109 1284 853 536 0 0 0 2 2788
USH2A 81 24 151 176 145 0 0 0 1 578
MYBPC3 170 27 226 116 22 0 0 0 0 561
MYH7 40 84 247 101 27 0 0 0 0 499
ADGRV1 26 3 133 167 141 0 0 0 0 470
CDH23 24 8 168 142 107 0 0 0 1 450
MYO7A 62 45 131 108 72 0 0 0 0 418
RYR2 2 4 124 119 78 0 0 0 2 329
MYO15A 21 10 106 103 69 0 0 0 0 309
DSP 2 42 124 75 45 0 0 0 0 288
OTOF 13 14 87 102 68 0 0 0 1 285
OTOG 0 11 59 107 86 0 0 0 1 264
FBN1 50 85 71 25 28 0 0 0 2 261
LOXHD1 8 1 113 85 53 0 0 0 1 261
PCDH15 10 2 79 68 77 0 0 0 1 237
WFS1 10 2 78 59 66 0 0 0 0 215
MYH6 0 0 83 56 46 0 0 0 2 187
TECTA 3 7 78 57 36 0 0 0 0 181
SCN5A 6 12 75 57 29 0 0 0 0 179
MYH9 1 0 44 89 43 0 0 0 0 177
SLC26A4 44 20 54 30 20 0 0 0 0 168
MYH14 0 0 57 56 54 0 0 0 0 167
PKP2 13 33 52 44 18 0 0 0 0 160
COL11A2 0 1 56 46 47 0 0 0 0 150
LAMA4 0 0 50 59 38 0 0 0 3 150
OTOGL 7 6 42 35 60 0 0 0 0 150
EGFR 8 9 46 22 5 53 0 0 3 144
RBM20 3 3 62 54 21 0 0 0 0 143
MUC5B 0 0 6 33 101 0 0 0 1 141
BRCA2 74 3 30 12 18 0 0 0 0 137
LMNA 20 28 46 30 12 0 0 0 1 137
TRIOBP 1 0 36 66 33 0 0 0 0 136
USH1C 2 0 55 40 38 0 0 0 0 135
TNNT2 12 21 59 19 11 0 0 0 0 122
LDB3 0 0 55 42 23 0 0 0 1 121
MYO3A 0 2 37 37 43 0 0 0 0 119
DSG2 2 6 49 37 20 0 0 0 3 117
PTPN11 61 12 19 20 5 0 0 0 0 117
GJB2 42 20 20 21 13 0 0 0 0 116
ACTN2 1 0 49 43 22 0 0 0 0 115
SOS1 19 8 44 24 18 0 0 0 0 113
DNAH11 5 0 13 18 73 0 0 0 0 109
NEBL 0 0 44 38 25 0 0 0 2 109
WHRN 2 0 36 40 30 0 0 0 0 108
BRAF 29 26 16 26 7 0 0 0 1 105
DNAH5 1 6 18 16 64 0 0 0 0 105
DMD 2 0 33 24 45 0 0 0 0 104
MYO6 4 8 42 29 20 0 0 0 1 104
MYOM1 0 0 23 30 51 0 0 0 0 104
ALMS1 0 0 21 28 54 0 0 0 0 103
STRC 19 4 37 24 17 0 0 0 0 101
ABCC9 0 0 39 39 21 0 0 0 1 100
TPM1 3 16 50 23 6 0 0 0 1 99
VCL 0 8 35 32 22 0 0 0 0 97
BRCA1 49 6 18 9 12 0 0 0 0 94
KCNQ1 6 13 26 31 17 0 0 0 0 93
RAF1 12 9 31 28 13 0 0 0 0 93
APC 10 6 55 6 11 0 0 0 0 88
DSC2 0 3 50 22 13 0 0 0 0 88
PRKAG2 2 5 36 32 12 0 0 0 1 88
CACNA1D 0 0 28 34 24 0 0 0 0 86
TNNI3 9 17 37 17 4 0 0 0 0 84
LDLR 36 20 17 3 7 0 0 0 0 83
PRDM16 0 0 22 28 32 0 0 0 0 82
MSH6 23 5 39 6 6 0 0 0 1 80
NF1 7 1 19 20 32 0 0 0 0 79
TMPRSS3 8 6 25 20 20 0 0 0 0 79
JUP 0 0 28 32 17 0 0 0 0 77
TMC1 12 4 33 19 7 0 0 0 2 77
MAP2K2 0 3 23 35 15 0 0 0 0 76
LAMP2 10 14 26 20 4 0 0 0 1 75
MHRT, MYH7 2 3 43 18 8 0 0 0 0 74
PLEC 0 0 5 4 64 0 0 0 0 73
DES 3 7 26 15 20 0 0 0 0 71
EDA 38 12 18 0 3 0 0 0 0 71
KRAS 23 11 11 21 5 0 0 0 0 71
ACTG1 0 3 9 39 19 0 0 0 0 70
NEXN 0 0 45 20 5 0 0 0 0 70
MYPN 0 0 19 23 27 0 0 0 0 69
POLE 0 0 57 2 10 0 0 0 0 69
RYR1 5 6 19 1 35 0 0 0 0 66
BAG3 2 6 23 20 14 0 0 0 0 65
MT-RNR1 1 1 9 28 23 0 0 0 0 62
OTOA 8 1 18 19 15 0 0 0 1 62
TBC1D24 0 1 18 25 18 0 0 0 0 62
KCNQ4 3 1 26 18 13 0 0 0 0 61
TSPEAR 0 0 23 20 18 0 0 0 0 61
DIAPH1 1 0 18 26 15 0 0 0 0 60
TJP2 0 0 15 17 28 0 0 0 0 60
EYA1 13 3 17 13 13 0 0 0 0 59
ILDR1 0 0 26 19 13 0 0 0 0 58
COL4A4 0 0 12 9 35 0 0 0 0 56
LARS2 1 2 10 21 21 0 0 0 0 55
MYLK2 0 0 19 25 11 0 0 0 0 55
TSC2 8 1 10 11 25 0 0 0 0 55
C10orf105, CDH23 4 0 23 10 17 0 0 0 0 54
MYO1A 0 0 14 26 13 0 0 0 1 54
CBL 3 3 20 18 10 0 0 0 0 53
TMEM43 1 0 26 13 13 0 0 0 0 53
ESRRB 0 7 16 17 12 0 0 0 0 52
PMS2 19 4 20 1 8 0 0 0 0 52
CHD7 0 0 10 15 23 0 0 0 0 48
GIPC3 2 1 14 24 7 0 0 0 0 48
MSH2 11 2 26 3 6 0 0 0 0 48
GLA, RPL36A-HNRNPH2 5 6 17 13 5 0 0 0 1 47
MYL2 1 7 22 14 3 0 0 0 0 47
ACTC1, LOC101928174 1 4 26 13 2 0 0 0 0 46
CASQ2 0 2 23 15 6 0 0 0 0 46
COL4A3, MFF-DT 0 0 5 13 28 0 0 0 0 46
TMPO 0 0 17 13 16 0 0 0 0 46
TRDN 0 0 11 11 24 0 0 0 0 46
CFTR 5 5 10 7 16 0 0 0 2 45
DOCK8 0 0 4 5 36 0 0 0 0 45
NEB 0 0 2 11 32 0 0 0 0 45
SGCD 0 2 11 9 14 0 0 0 9 45
MAP2K1 3 6 12 15 8 0 0 0 0 44
ATP6V1B1 1 0 16 11 15 0 0 0 0 43
DTNA 0 0 12 17 14 0 0 0 0 43
ELN 20 4 6 5 8 0 0 0 0 43
GSDME 1 1 12 15 14 0 0 0 0 43
PDZD7 0 1 12 11 19 0 0 0 0 43
HRAS, LRRC56 7 5 12 11 5 0 0 0 2 42
MLH1 6 0 25 5 6 0 0 0 0 42
MITF 6 0 19 11 5 0 0 0 0 41
RET 5 1 14 6 14 0 0 0 0 40
MARVELD2 2 0 15 16 6 0 0 0 0 39
CSRP3 0 0 23 7 4 0 0 0 4 38
CCDC40 2 0 4 6 25 0 0 0 0 37
GPSM2 5 0 11 11 10 0 0 0 0 37
LOC102723833, USH2A 7 1 9 15 5 0 0 0 0 37
MYL3 0 2 22 10 2 0 0 0 1 37
SERPINB6 0 1 10 20 6 0 0 0 0 37
CCDC50 0 0 11 7 18 0 0 0 0 36
CEACAM16 0 1 6 14 15 0 0 0 0 36
DNAH17 0 0 0 2 34 0 0 0 0 36
HSD17B4 0 1 7 11 17 0 0 0 0 36
LTBP4 1 0 6 5 22 0 0 0 1 35
TGFBR2 3 4 16 5 7 0 0 0 0 35
APOB 2 2 18 3 9 0 0 0 0 34
GRHL2 0 0 12 12 10 0 0 0 0 34
MYLK 0 0 3 3 28 0 0 0 0 34
RIPOR2 0 0 3 7 24 0 0 0 0 34
ABCA3 1 3 8 8 13 0 0 0 0 33
EYA4 1 3 15 9 6 0 0 0 0 33
MUTYH 7 2 19 0 5 0 0 0 0 33
SYNE4 0 3 7 12 11 0 0 0 0 33
TP53 10 8 11 2 2 0 0 0 0 33
BSND 0 0 9 16 7 0 0 0 0 32
P2RX2 0 0 9 8 15 0 0 0 0 32
LOC101927055, TTN 0 1 12 5 13 0 0 0 0 31
PAX3 5 1 7 7 11 0 0 0 0 31
FHL2 0 0 12 8 10 0 0 0 0 30
JPH2 0 0 10 8 12 0 0 0 0 30
KCNE1 0 2 16 8 4 0 0 0 0 30
KCNH2 1 4 19 1 5 0 0 0 0 30
MYOZ2 0 0 11 11 7 0 0 0 1 30
ESPN 0 0 11 12 6 0 0 0 0 29
KARS1 0 0 12 8 9 0 0 0 0 29
RDX 1 0 13 13 2 0 0 0 0 29
SLC52A3 0 0 4 9 16 0 0 0 0 29
ANKRD1 0 0 12 10 6 0 0 0 0 28
USH1G 0 1 14 9 4 0 0 0 0 28
COCH, LOC100506071 2 1 6 7 11 0 0 0 0 27
GRXCR1 1 1 8 10 6 0 0 0 1 27
LOC110121269, SCN5A 0 1 14 6 6 0 0 0 0 27
NLRP3 0 0 2 8 17 0 0 0 0 27
TERT 0 1 7 7 11 0 0 0 1 27
DNAAF1 0 0 3 3 20 0 0 0 0 26
HGF 0 0 10 10 5 0 0 0 1 26
TTR 4 2 7 6 6 0 0 0 1 26
DNAH14 0 0 1 1 23 0 0 0 0 25
DYSF 0 1 2 0 22 0 0 0 0 25
TNNC1 0 1 14 10 0 0 0 0 0 25
EPS8 0 0 4 8 12 0 0 0 0 24
LOC114827851, MYH6 0 0 11 4 9 0 0 0 0 24
POLR2F, SOX10 2 2 6 9 5 0 0 0 0 24
POU4F3 0 1 11 6 6 0 0 0 0 24
RPGR 0 0 2 2 20 0 0 0 0 24
TAZ 4 7 8 2 3 0 0 0 0 24
FLNC 0 0 4 0 19 0 0 0 0 23
TGFBR1 3 0 12 5 3 0 0 0 0 23
TMIE 0 2 9 8 4 0 0 0 0 23
EDNRB 1 0 5 6 10 0 0 0 0 22
FBN2 0 0 1 1 20 0 0 0 0 22
GJB3 0 0 6 6 10 0 0 0 0 22
PJVK 1 0 8 7 6 0 0 0 0 22
POLD1 0 0 20 1 1 0 0 0 0 22
TCAP 0 1 12 4 5 0 0 0 0 22
TSC1 4 0 3 5 10 0 0 0 0 22
CEP78 0 0 4 6 11 0 0 0 0 21
CLDN14 0 0 6 7 8 0 0 0 0 21
CLRN1 6 1 4 5 5 0 0 0 0 21
POU3F4 3 4 6 4 3 0 0 0 0 20
SDHB 3 6 6 2 3 0 0 0 0 20
SPINK5 0 1 1 0 18 0 0 0 0 20
TPRN 0 0 6 9 5 0 0 0 0 20
AP3B1 0 0 2 1 16 0 0 0 0 19
CSF2RB 0 0 4 1 14 0 0 0 0 19
DOLK 0 0 5 9 5 0 0 0 0 19
EMD 2 1 7 6 3 0 0 0 0 19
GATAD1 0 0 6 9 4 0 0 0 0 19
HARS2 0 0 9 7 3 0 0 0 0 19
LRTOMT 1 1 6 7 4 0 0 0 0 19
SFTPA1 0 0 7 3 9 0 0 0 0 19
SPRED1 1 0 4 7 7 0 0 0 0 19
ADCY1 0 0 3 5 10 0 0 0 0 18
CAVIN4 0 0 3 8 7 0 0 0 0 18
CLIC5 0 0 2 8 8 0 0 0 0 18
COL3A1 0 5 2 1 10 0 0 0 0 18
CTF1 0 0 10 6 2 0 0 0 0 18
DNAH10 0 0 1 1 16 0 0 0 0 18
MSRB3 0 1 2 7 8 0 0 0 0 18
PDLIM3 0 0 3 2 13 0 0 0 0 18
RSPH4A 0 1 2 4 11 0 0 0 0 18
CAV3 0 1 0 11 5 0 0 0 0 17
CDC14A 0 1 2 4 10 0 0 0 0 17
COL4A5 0 1 0 4 12 0 0 0 0 17
DNAH6 0 0 0 1 16 0 0 0 0 17
DNAI1 2 0 4 2 9 0 0 0 0 17
DNAI2 1 1 1 3 11 0 0 0 0 17
DYNC2H1 0 1 0 0 16 0 0 0 0 17
DNAAF2 0 2 5 2 7 0 0 0 0 16
DNAH8 0 0 1 1 14 0 0 0 0 16
ENG 0 0 3 3 10 0 0 0 0 16
HPS1 2 0 1 1 12 0 0 0 0 16
MYH11, NDE1 0 0 1 1 14 0 0 0 0 16
SCNN1A 0 1 3 3 9 0 0 0 0 16
SLC26A5 0 0 1 7 6 0 0 0 2 16
CCDC39 0 0 4 3 8 0 0 0 0 15
CLPP 0 0 2 7 6 0 0 0 0 15
CRYAB 0 2 6 4 3 0 0 0 0 15
CSF2RA 0 0 0 4 11 0 0 0 0 15
DNAH2 0 0 1 3 11 0 0 0 0 15
DNAH9 0 0 0 0 15 0 0 0 0 15
GJB6 1 0 5 4 5 0 0 0 0 15
LDB3, LOC110121486 1 0 2 8 4 0 0 0 0 15
NME8 0 0 0 2 13 0 0 0 0 15
DNAAF3, TNNI3 0 0 0 0 14 0 0 0 0 14
DNAH1 0 1 4 1 8 0 0 0 0 14
DNAH12 0 0 0 0 14 0 0 0 0 14
ERBB2 1 9 2 1 0 0 0 0 1 14
HPS4 0 1 0 2 11 0 0 0 0 14
JAG1 1 0 1 0 12 0 0 0 0 14
LHFPL5 0 1 9 4 0 0 0 0 0 14
MYH11 0 0 2 2 10 0 0 0 0 14
RIT1 5 2 3 1 3 0 0 0 0 14
SDHD 4 1 3 1 5 0 0 0 0 14
SLC17A8 0 0 6 1 7 0 0 0 0 14
SLITRK6 0 0 4 2 8 0 0 0 0 14
SPEF2 0 0 3 0 11 0 0 0 0 14
CDH23, PSAP 0 0 3 2 8 0 0 0 0 13
CEP85L, PLN 3 0 7 2 1 0 0 0 0 13
CLCNKB, LOC106501713 0 0 0 1 12 0 0 0 0 13
DNAH7 0 0 0 2 11 0 0 0 0 13
EYA4, TARID 0 1 6 5 1 0 0 0 0 13
HPS5 0 0 0 3 10 0 0 0 0 13
LOC107303340, VHL 9 1 2 1 0 0 0 0 0 13
POMT1 0 1 1 1 10 0 0 0 0 13
RTEL1, RTEL1-TNFRSF6B 0 1 3 2 7 0 0 0 0 13
CIITA 1 1 0 0 10 0 0 0 0 12
CRYM 0 0 4 3 5 0 0 0 0 12
LOC114827850, MYL2 0 2 6 2 2 0 0 0 0 12
MEN1 3 0 6 0 3 0 0 0 0 12
MYO5B 0 1 0 0 11 0 0 0 0 12
NPC1 2 3 1 1 5 0 0 0 0 12
PIGN 0 2 0 0 10 0 0 0 0 12
PIK3CA 8 2 1 1 0 0 0 0 0 12
SCNN1B 0 0 1 4 7 0 0 0 0 12
SERPINA1 1 1 1 1 7 0 0 0 1 12
SFTPB 0 0 1 3 8 0 0 0 0 12
SFTPD 0 0 1 1 10 0 0 0 0 12
VHL 4 3 3 1 1 0 0 0 0 12
EDN3 0 0 2 5 4 0 0 0 0 11
HARS1 0 0 3 3 5 0 0 0 0 11
IGHMBP2 2 1 0 1 7 0 0 0 0 11
ILK, TAF10 0 0 4 4 3 0 0 0 0 11
OSBPL2 0 0 1 2 8 0 0 0 0 11
PTEN 4 3 2 1 1 0 0 0 0 11
SLC52A2 1 0 0 7 3 0 0 0 0 11
TAP2 0 0 0 0 11 0 0 0 0 11
CBS 2 0 0 1 7 0 0 0 0 10
CHRM2, LOC349160 0 0 3 4 3 0 0 0 0 10
CIB2 0 1 1 3 5 0 0 0 0 10
DIABLO 0 0 7 2 1 0 0 0 0 10
EIF2AK4 0 1 0 0 9 0 0 0 0 10
FLCN 0 2 1 1 6 0 0 0 0 10
HPS3 1 0 0 2 7 0 0 0 0 10
NEB, RIF1 0 1 1 0 8 0 0 0 0 10
NRAS 4 0 2 4 0 0 0 0 0 10
S1PR2 0 0 1 2 7 0 0 0 0 10
SCNN1G 0 0 0 1 9 0 0 0 0 10
SFTPA2 0 0 1 1 8 0 0 0 0 10
BCS1L 0 1 1 2 5 0 0 0 0 9
C5 0 1 0 0 8 0 0 0 0 9
CABP2 0 0 2 4 3 0 0 0 0 9
DRC1 0 0 1 0 8 0 0 0 0 9
DTNBP1 0 0 0 2 7 0 0 0 0 9
FAT4 0 1 0 1 7 0 0 0 0 9
MT-TS1 1 0 3 3 2 0 0 0 0 9
PLCG2 0 0 0 0 9 0 0 0 0 9
STK11 0 0 7 1 1 0 0 0 0 9
ULK4 0 0 0 0 9 0 0 0 0 9
ANAPC15, LRTOMT 0 0 5 2 1 0 0 0 0 8
ASCL1, PAH 0 0 2 4 2 0 0 0 0 8
DNAH3 0 0 0 3 5 0 0 0 0 8
DSC2, DSCAS 0 0 2 0 1 0 0 0 5 8
HIVEP3 0 0 0 0 8 0 0 0 0 8
HPS6 0 1 1 4 2 0 0 0 0 8
IL12RB1 0 0 0 0 8 0 0 0 0 8
LAMA3 0 0 0 0 8 0 0 0 0 8
LRBA 0 0 0 1 7 0 0 0 0 8
LYST 0 0 0 1 7 0 0 0 0 8
MEGF10 0 0 0 0 8 0 0 0 0 8
MUC4 0 0 1 0 7 0 0 0 0 8
PCSK9 1 0 6 0 1 0 0 0 0 8
SETX 0 0 0 0 8 0 0 0 0 8
SHOC2 1 0 1 5 1 0 0 0 0 8
SLC5A1 0 0 0 0 8 0 0 0 0 8
ABCA4 5 2 0 0 0 0 0 0 0 7
ACTA2 2 2 3 0 0 0 0 0 0 7
ACVRL1 0 0 2 1 4 0 0 0 0 7
ALK 0 0 0 0 7 0 0 0 0 7
ANO5 2 0 0 0 5 0 0 0 0 7
BCL9L 0 0 0 0 7 0 0 0 0 7
BIN1 0 0 0 0 7 0 0 0 0 7
CACNA1S 0 0 7 0 0 0 0 0 0 7
CACNB2, NSUN6 0 0 7 0 0 0 0 0 0 7
CAV3, SSUH2 0 0 1 3 2 0 0 0 1 7
CHAT 0 1 0 0 6 0 0 0 0 7
FLG 3 0 0 0 4 0 0 0 0 7
HYDIN 0 0 0 0 7 0 0 0 0 7
KCNQ1, KCNQ1OT1 0 1 2 2 2 0 0 0 0 7
LIG1 0 0 0 0 7 0 0 0 0 7
NBN 0 1 0 1 5 0 0 0 0 7
NKX2-5 0 2 2 1 2 0 0 0 0 7
RB1 1 0 2 3 1 0 0 0 0 7
RSPH1 1 1 0 0 5 0 0 0 0 7
RTTN 0 0 0 0 7 0 0 0 0 7
SDHC 2 2 2 0 1 0 0 0 0 7
SKI 0 0 1 2 4 0 0 0 0 7
SMAD9 0 0 2 3 2 0 0 0 0 7
SP110, SP140 0 1 0 0 6 0 0 0 0 7
ACTA1 1 0 0 0 5 0 0 0 0 6
ADA 0 2 1 0 3 0 0 0 0 6
ALPK3 0 3 1 0 2 0 0 0 0 6
APTX 1 1 0 1 3 0 0 0 0 6
AQP7 0 0 0 0 6 0 0 0 0 6
ASAH1 0 1 0 0 5 0 0 0 0 6
ATP7B 3 2 1 0 0 0 0 0 0 6
BCLAF1 0 0 1 0 5 0 0 0 0 6
BLM 2 0 0 0 4 0 0 0 0 6
BLOC1S3 0 0 1 1 4 0 0 0 0 6
CCDC40, GAA 0 0 0 0 6 0 0 0 0 6
CCDC65 0 1 0 0 5 0 0 0 0 6
CCP110 0 0 0 0 6 0 0 0 0 6
CDH23, LOC111982869 2 1 1 1 1 0 0 0 0 6
CR2 0 0 1 0 5 0 0 0 0 6
DNMT3B 0 0 0 0 6 0 0 0 0 6
DYNC1H1 0 0 0 0 6 0 0 0 0 6
EDAR 3 0 0 0 3 0 0 0 0 6
FBLN5 0 0 2 0 4 0 0 0 0 6
FCGR2A 0 0 0 0 6 0 0 0 0 6
FCGR3A 0 0 1 1 4 0 0 0 0 6
FPR1 0 0 0 0 6 0 0 0 0 6
HNF1A 0 0 5 0 1 0 0 0 0 6
ITGB2 0 0 0 0 6 0 0 0 0 6
KCNN3 0 0 1 0 5 0 0 0 0 6
KIF27 0 0 0 0 6 0 0 0 0 6
LOC110011216, PHOX2B 2 0 0 1 3 0 0 0 0 6
LRIG1 0 0 0 0 6 0 0 0 0 6
NPC1L1 0 0 1 1 4 0 0 0 0 6
POLG 2 2 0 2 0 0 0 0 0 6
RNASEH2A 0 1 0 0 5 0 0 0 0 6
SELENON 1 0 0 0 5 0 0 0 0 6
SHROOM3 0 0 0 0 6 0 0 0 0 6
SP110 0 0 0 0 6 0 0 0 0 6
TIMM8A 0 0 2 1 2 0 0 0 1 6
UNC13D 0 0 1 1 4 0 0 0 0 6
ABCC6 2 0 3 0 0 0 0 0 0 5
AHNAK2 0 0 0 0 5 0 0 0 0 5
BMPR2 1 0 1 0 3 0 0 0 0 5
BPI 0 0 0 0 5 0 0 0 0 5
C6 1 1 1 0 2 0 0 0 0 5
C8A 0 0 0 0 5 0 0 0 0 5
CAPN3 1 0 0 0 4 0 0 0 0 5
CCDC103 1 1 0 0 3 0 0 0 0 5
CCDC114 0 0 0 0 5 0 0 0 0 5
CCDC39, TTC14 0 0 1 0 4 0 0 0 0 5
CLCC1, GPSM2 0 0 1 1 3 0 0 0 0 5
COG6 0 0 0 0 5 0 0 0 0 5
CTSC 0 1 0 0 4 0 0 0 0 5
CUBN 1 2 0 0 2 0 0 0 0 5
CYP11B2, LOC106799834 0 0 0 0 5 0 0 0 0 5
CYP1B1 2 0 3 0 0 0 0 0 0 5
DHCR7 2 1 0 0 2 0 0 0 0 5
DNAAF4, DNAAF4-CCPG1 0 1 0 0 4 0 0 0 0 5
DNASE1L1, TAZ 0 1 1 3 0 0 0 0 0 5
EPG5 1 0 0 0 4 0 0 0 0 5
ERCC2 0 1 0 0 4 0 0 0 0 5
FOXN1 0 0 0 0 5 0 0 0 0 5
GAS8 0 0 0 0 5 0 0 0 0 5
GATA4 0 0 0 1 4 0 0 0 0 5
GPD1L 0 0 4 0 1 0 0 0 0 5
IL17RA 0 0 0 0 5 0 0 0 0 5
IL7R 0 0 0 0 5 0 0 0 0 5
KITLG 0 0 1 1 3 0 0 0 0 5
MICA 0 0 0 0 5 0 0 0 0 5
MMP1 0 0 0 0 5 0 0 0 0 5
MMP3 0 0 0 0 5 0 0 0 0 5
NLRP12 0 0 0 0 5 0 0 0 0 5
NOD2 0 0 0 0 5 0 0 0 0 5
NOS3 0 0 0 0 5 0 0 0 0 5
NOTCH1 0 0 4 0 1 0 0 0 0 5
OCA2 2 1 0 2 0 0 0 0 0 5
OTOP2, USH1G 0 0 4 1 0 0 0 0 0 5
PAH 4 1 0 0 0 0 0 0 0 5
PALLD 0 0 0 0 5 0 0 0 0 5
PKHD1 2 0 0 1 2 0 0 0 0 5
PNP 0 1 0 0 4 0 0 0 0 5
PRKCD 0 0 0 0 5 0 0 0 0 5
PRPS1 0 0 0 3 2 0 0 0 0 5
PXDNL 0 0 0 0 5 0 0 0 0 5
RSPH9 0 0 1 2 2 0 0 0 0 5
SCN1B 0 0 4 0 1 0 0 0 0 5
SGCG 2 0 0 0 3 0 0 0 0 5
SLC12A3 0 0 2 1 2 0 0 0 0 5
SLC22A12 1 0 0 0 4 0 0 0 0 5
SLC26A9 0 0 0 0 5 0 0 0 0 5
SLC39A4 0 0 0 1 4 0 0 0 0 5
SMAD3 0 2 0 0 3 0 0 0 0 5
SMPD1 0 1 1 0 3 0 0 0 0 5
STXBP2 0 0 0 2 3 0 0 0 0 5
THBS1 0 0 0 0 5 0 0 0 0 5
TNFRSF13B 0 0 1 0 4 0 0 0 0 5
TRNT1 0 0 0 0 5 0 0 0 0 5
TYR 3 2 0 0 0 0 0 0 0 5
VWF 1 1 2 0 1 0 0 0 0 5
WT1 1 0 4 0 0 0 0 0 0 5
ADA2 0 0 0 0 4 0 0 0 0 4
AK5 0 0 0 0 4 0 0 0 0 4
AK7 0 0 0 0 4 0 0 0 0 4
APOL1 0 0 0 0 1 0 0 0 3 4
ATM 0 0 0 0 4 0 0 0 0 4
ATR 0 0 0 0 4 0 0 0 0 4
BDNF 0 0 1 0 3 0 0 0 0 4
BMP1, SFTPC 0 0 0 0 4 0 0 0 0 4
BMPR1A 0 0 4 0 0 0 0 0 0 4
BRIP1 0 0 1 0 3 0 0 0 0 4
BTD 3 1 0 0 0 0 0 0 0 4
C4BPB 0 0 0 0 4 0 0 0 0 4
CACNA1C 0 0 3 0 1 0 0 0 0 4
CACNB2 0 0 4 0 0 0 0 0 0 4
CARD11 0 0 0 0 4 0 0 0 0 4
CARD14 0 0 1 0 3 0 0 0 0 4
CARD14, SGSH 0 0 0 1 3 0 0 0 0 4
CASQ2, VANGL1 0 0 0 0 4 0 0 0 0 4
CATSPER2 2 0 1 0 1 0 0 0 0 4
CDH1 0 0 0 1 3 0 0 0 0 4
CFTR, LOC111674472 1 0 1 1 1 0 0 0 0 4
CNGA3 2 1 1 0 0 0 0 0 0 4
CRPPA 0 0 0 0 4 0 0 0 0 4
CTNS 1 0 0 0 3 0 0 0 0 4
DAG1 0 0 0 1 3 0 0 0 0 4
DCLRE1C 0 0 0 1 3 0 0 0 0 4
DNAAF5 0 0 0 0 4 0 0 0 0 4
DNAL1 0 1 1 1 1 0 0 0 0 4
DYNC1I1 0 0 0 1 3 0 0 0 0 4
EDNRB, LOC107882129 0 0 3 0 1 0 0 0 0 4
EFEMP2 0 0 0 1 3 0 0 0 0 4
ELMOD2 0 0 0 1 3 0 0 0 0 4
EVI5 0 0 0 0 4 0 0 0 0 4
F12, SLC34A1 1 0 0 0 3 0 0 0 0 4
FAM20C 0 0 0 0 4 0 0 0 0 4
FBN1, LOC113939944 2 0 1 0 1 0 0 0 0 4
FERMT3 0 0 0 0 4 0 0 0 0 4
FKTN 0 1 0 0 3 0 0 0 0 4
G6PD 1 1 0 0 2 0 0 0 0 4
GBA, LOC106627981 2 1 0 0 1 0 0 0 0 4
GDNF 0 0 1 2 1 0 0 0 0 4
GFI1 0 0 0 0 4 0 0 0 0 4
GPR179 1 2 1 0 0 0 0 0 0 4
HDAC9 0 0 0 1 3 0 0 0 0 4
HIVEP1 0 0 0 0 4 0 0 0 0 4
IFNGR1 1 0 0 0 3 0 0 0 0 4
IL1RN 0 0 0 0 4 0 0 0 0 4
IRF2BP2 0 0 0 0 4 0 0 0 0 4
KMT2C 1 0 0 0 3 0 0 0 0 4
KMT2D 0 0 0 0 4 0 0 0 0 4
LOC100128979, TPM1 0 0 4 0 0 0 0 0 0 4
LPIN1 0 0 0 0 4 0 0 0 0 4
MANBA 0 0 0 0 4 0 0 0 0 4
MIR96 0 0 2 1 1 0 0 0 0 4
MMUT 1 0 0 0 3 0 0 0 0 4
NEK2 0 0 0 0 4 0 0 0 0 4
NFKB2 0 0 0 0 4 0 0 0 0 4
NLRP7 1 0 0 0 3 0 0 0 0 4
NUP188 0 0 0 0 4 0 0 0 0 4
ORC4 0 0 0 0 4 0 0 0 0 4
PALB2 2 0 1 1 0 0 0 0 0 4
PHOX2B 0 0 0 0 4 0 0 0 0 4
PIK3R1 0 0 0 0 4 0 0 0 0 4
POMT2 0 0 0 0 4 0 0 0 0 4
PRF1 0 1 0 0 3 0 0 0 0 4
PROP1 0 0 0 1 3 0 0 0 0 4
RASGRP2 0 0 0 1 3 0 0 0 0 4
RECQL4 0 1 0 0 3 0 0 0 0 4
SBDS 2 0 0 1 1 0 0 0 0 4
SDHAF2 0 0 4 0 0 0 0 0 0 4
SERAC1 0 2 0 0 2 0 0 0 0 4
SIX1 0 0 1 1 2 0 0 0 0 4
SKIV2L 0 0 0 0 4 0 0 0 0 4
SLC22A5 1 1 2 0 0 0 0 0 0 4
SLC2A10 0 0 1 1 2 0 0 0 0 4
SLC34A3 0 0 0 0 4 0 0 0 0 4
SLC7A9 1 1 2 0 0 0 0 0 0 4
SPAG1 0 0 1 0 3 0 0 0 0 4
SPG7 2 1 0 0 1 0 0 0 0 4
STAT2 0 0 0 1 3 0 0 0 0 4
SYNE1 0 2 2 0 0 0 0 0 0 4
TCIRG1 1 0 0 0 3 0 0 0 0 4
TICAM1 0 0 0 0 4 0 0 0 0 4
TNFRSF11A 0 0 0 0 4 0 0 0 0 4
TTC7A 0 0 0 1 3 0 0 0 0 4
ACADM 2 1 0 0 0 0 0 0 0 3
ACP5, ZNF627 0 0 0 0 3 0 0 0 0 3
ACVR2B 0 0 0 0 3 0 0 0 0 3
ADAMTS13 0 1 0 1 1 0 0 0 0 3
AICDA 0 0 0 0 3 0 0 0 0 3
AKAP9 0 0 0 0 3 0 0 0 0 3
ARMC4 1 0 0 0 2 0 0 0 0 3
ASPA, SPATA22 2 1 0 0 0 0 0 0 0 3
AXIN2 0 0 0 0 3 0 0 0 0 3
BARD1 0 0 0 0 3 0 0 0 0 3
BBS10 1 2 0 0 0 0 0 0 0 3
BTK 0 0 0 1 2 0 0 0 0 3
C12orf60, GUCY2C 0 0 0 0 3 0 0 0 0 3
C17orf107, CHRNE 1 0 1 0 1 0 0 0 0 3
C1S 0 0 0 1 2 0 0 0 0 3
C2 0 1 0 0 2 0 0 0 0 3
C2, CFB 0 0 0 0 3 0 0 0 0 3
CACNA1A 0 1 1 0 1 0 0 0 0 3
CASP8 0 0 0 0 3 0 0 0 0 3
CCDC151 0 0 1 0 2 0 0 0 0 3
CCDC85C, CCNK 0 0 0 3 0 0 0 0 0 3
CD164 0 0 0 2 1 0 0 0 0 3
CD8A 0 0 0 0 3 0 0 0 0 3
CDCA7L, DNAH11 0 0 0 0 3 0 0 0 0 3
CDKN2A 0 0 1 1 1 0 0 0 0 3
CERS1, GDF1 0 0 0 0 3 0 0 0 0 3
CLDN16 0 0 0 0 3 0 0 0 0 3
COL2A1 0 2 1 0 0 0 0 0 0 3
COL4A3 0 0 0 1 2 0 0 0 0 3
COL6A2 1 0 0 1 1 0 0 0 0 3
COL7A1 1 2 0 0 0 0 0 0 0 3
CTSA 0 0 0 0 3 0 0 0 0 3
CYP24A1 0 1 1 0 1 0 0 0 0 3
CYP2C9 0 0 0 0 0 3 0 0 0 3
DGAT1 0 0 0 1 2 0 0 0 0 3
DSG1 0 0 0 0 3 0 0 0 0 3
DUOX2 2 1 0 0 0 0 0 0 0 3
ENG, LOC102723566 0 0 3 0 0 0 0 0 0 3
EPCAM 0 0 1 0 2 0 0 0 0 3
EYS 2 0 1 0 0 0 0 0 0 3
F5 0 1 0 1 0 0 1 0 0 3
F8 0 1 1 0 1 0 0 0 0 3
FKRP 1 0 0 0 2 0 0 0 0 3
FLT4 0 0 0 0 3 0 0 0 0 3
FOCAD 0 0 0 0 3 0 0 0 0 3
FOXF1 1 0 0 0 2 0 0 0 0 3
GAA 2 1 0 0 0 0 0 0 0 3
GATA2 0 0 0 0 3 0 0 0 0 3
GCK 1 2 0 0 0 0 0 0 0 3
GFM1 0 1 0 2 0 0 0 0 0 3
GNPTG 0 2 1 0 0 0 0 0 0 3
GRHPR 1 0 0 0 2 0 0 0 0 3
HARS1, HARS2 0 0 2 1 0 0 0 0 0 3
HCN2 0 0 1 2 0 0 0 0 0 3
HERC2 0 0 0 0 3 0 0 0 0 3
HEXA 1 0 0 0 1 0 0 1 0 3
HEXD 0 0 0 0 3 0 0 0 0 3
HOGA1 2 0 0 0 1 0 0 0 0 3
HSPH1 0 0 2 0 1 0 0 0 0 3
ICOS 0 0 1 0 2 0 0 0 0 3
IFT88 0 0 0 0 3 0 0 0 0 3
ITGA9 0 0 0 0 3 0 0 0 0 3
KIF1B 0 0 0 0 3 0 0 0 0 3
KIF26B 0 0 0 0 3 0 0 0 0 3
KLHL40 0 0 1 0 2 0 0 0 0 3
LBR 0 0 0 0 3 0 0 0 0 3
LIG4 0 1 0 0 2 0 0 0 0 3
LOC105378311, PCDH15 0 0 1 1 1 0 0 0 0 3
LPIN2 0 0 1 1 1 0 0 0 0 3
MAN2B1 0 0 0 0 3 0 0 0 0 3
MBL2 0 0 0 1 2 0 0 0 0 3
MEFV 1 1 1 0 0 0 0 0 0 3
MMAB, MVK 0 0 0 0 3 0 0 0 0 3
MMP8 0 0 0 1 2 0 0 0 0 3
MPI 0 0 0 0 3 0 0 0 0 3
MSH5, MSH5-SAPCD1 0 0 0 0 3 0 0 0 0 3
NCF4 0 0 0 0 3 0 0 0 0 3
NF2 0 0 3 0 0 0 0 0 0 3
NFKBIA 0 0 0 0 3 0 0 0 0 3
NLRC4 0 0 0 1 2 0 0 0 0 3
NLRP1 0 0 0 0 3 0 0 0 0 3
NR3C2 0 0 0 0 3 0 0 0 0 3
ORAI1 0 0 0 0 3 0 0 0 0 3
PDE6B 2 1 0 0 0 0 0 0 0 3
PEPD 1 0 0 0 2 0 0 0 0 3
PEX1 0 0 0 1 2 0 0 0 0 3
PICALM 0 0 0 0 3 0 0 0 0 3
PIGV 0 1 1 1 0 0 0 0 0 3
PRSS1, TRB 1 0 0 0 2 0 0 0 0 3
RNF43 0 0 0 0 3 0 0 0 0 3
RPGRIP1L 0 2 0 0 1 0 0 0 0 3
SACS 2 1 0 0 0 0 0 0 0 3
SACS, SGCG 0 0 0 0 3 0 0 0 0 3
SCARF2 0 0 0 0 3 0 0 0 0 3
SEC63 0 0 0 3 0 0 0 0 0 3
SH3BP2 0 0 0 0 3 0 0 0 0 3
SHARPIN 0 0 0 0 3 0 0 0 0 3
SI 0 3 0 0 0 0 0 0 0 3
SLC35C1 0 1 0 0 2 0 0 0 0 3
SPATC1L 0 0 0 0 3 0 0 0 0 3
STAT3 0 0 0 2 1 0 0 0 0 3
STK36 0 0 0 1 2 0 0 0 0 3
TAP1 0 0 0 0 3 0 0 0 0 3
TBK1 0 0 0 0 3 0 0 0 0 3
TBX1 0 0 1 0 2 0 0 0 0 3
TBX4 0 0 0 0 3 0 0 0 0 3
TLR3 0 0 1 0 2 0 0 0 0 3
TMC6 0 0 0 0 3 0 0 0 0 3
TNFRSF1A 0 0 1 0 2 0 0 0 0 3
TNNT1 0 0 0 0 3 0 0 0 0 3
TNXB 0 0 1 0 2 0 0 0 0 3
TRIP10 0 0 0 0 3 0 0 0 0 3
TSHR 1 1 0 1 0 0 0 0 0 3
TTLL1 0 0 0 0 3 0 0 0 0 3
TYK2 0 0 0 0 3 0 0 0 0 3
VAV1 0 0 0 0 3 0 0 0 0 3
VPS13B 0 1 0 0 2 0 0 0 0 3
ZAN 0 0 0 0 3 0 0 0 0 3
ZAP70 0 0 1 0 2 0 0 0 0 3
ZFPM2 0 0 1 0 2 0 0 0 0 3
ABCB4 0 0 1 1 0 0 0 0 0 2
ACR 0 0 0 0 2 0 0 0 0 2
ADSL 1 0 1 0 0 0 0 0 0 2
AGA 0 0 0 0 2 0 0 0 0 2
AGL 0 1 0 1 0 0 0 0 0 2
AGXT 1 0 0 0 1 0 0 0 0 2
AIP 0 0 1 0 1