List of variants in gene APC reported as pathogenic by PreventionGenetics, part of Exact Sciences

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 17

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HGVS	dbSNP	gnomAD frequency
NM_000038.6(APC):c.1213C>T (p.Arg405Ter)	rs587779780	0.00001
NM_000038.6(APC):c.3149del (p.Ala1050fs)	rs730882135	0.00001
NM_000038.6(APC):c.1095del (p.Asp366fs)
NM_000038.6(APC):c.1312+1G>C
NM_000038.6(APC):c.1312+3A>G	rs863225311
NM_000038.6(APC):c.1408+1330del
NM_000038.6(APC):c.1743+1G>A	rs761458613
NM_000038.6(APC):c.233_236del (p.Asp78fs)	rs1064793020
NM_000038.6(APC):c.2413C>T (p.Arg805Ter)	rs587779783
NM_000038.6(APC):c.2547_2550del (p.Asp849fs)	rs398123118
NM_000038.6(APC):c.3810T>A (p.Cys1270Ter)	rs863225347
NM_000038.6(APC):c.3982C>T (p.Gln1328Ter)	rs398123121
NM_000038.6(APC):c.4506T>A (p.Cys1502Ter)
NM_000038.6(APC):c.5572C>T (p.Arg1858Ter)	rs1270783041
NM_000038.6(APC):c.5936_5939del (p.Asn1979fs)	rs587781330
NM_000038.6(APC):c.643C>T (p.Gln215Ter)	rs137854577
NM_000038.6(APC):c.790C>T (p.Gln264Ter)

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