List of variants in gene APOB reported by PreventionGenetics, part of Exact Sciences

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
		ClinVar version:

Total variants: 137

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HGVS	dbSNP	gnomAD frequency
NM_000384.3(APOB):c.7545C>T (p.Thr2515=)	rs693	0.38722
NM_000384.3(APOB):c.2706C>T (p.Asn902=)	rs1801700	0.03627
NM_000384.3(APOB):c.11904-7C>T	rs12720851	0.03622
NM_000384.3(APOB):c.10737C>T (p.Thr3579=)	rs12713554	0.02896
NM_000384.3(APOB):c.11808C>T (p.Ile3936=)	rs12720852	0.01624
NM_000384.3(APOB):c.3509-10G>A	rs12720770	0.01624
NM_000384.3(APOB):c.2604+15G>C	rs72653066	0.00842
NM_000384.3(APOB):c.905-15C>G	rs72653061	0.00554
NM_000384.3(APOB):c.3383G>A (p.Arg1128His)	rs12713843	0.00356
NM_000384.3(APOB):c.7696G>A (p.Glu2566Lys)	rs1801696	0.00305
NM_000384.3(APOB):c.8462C>T (p.Pro2821Leu)	rs72653095	0.00267
NM_000384.3(APOB):c.13369G>A (p.Asp4457Asn)	rs183812948	0.00250
NM_000384.3(APOB):c.1785C>G (p.Ser595=)	rs139864087	0.00247
NM_000384.3(APOB):c.3843C>T (p.Ser1281=)	rs72653079	0.00240
NM_000384.3(APOB):c.3150A>G (p.Thr1050=)	rs72653072	0.00231
NM_000384.3(APOB):c.12803T>C (p.Met4268Thr)	rs72654422	0.00222
NM_000384.3(APOB):c.7242A>C (p.Glu2414Asp)	rs72653091	0.00222
NM_000384.3(APOB):c.8889C>T (p.Ile2963=)	rs72653097	0.00213
NM_000384.3(APOB):c.11833A>G (p.Thr3945Ala)	rs1801698	0.00212
NM_000384.3(APOB):c.7615G>A (p.Val2539Ile)	rs148170480	0.00210
NM_000384.3(APOB):c.12766G>A (p.Glu4256Lys)	rs61743313	0.00198
NM_000384.3(APOB):c.751G>A (p.Ala251Thr)	rs61741625	0.00190
NM_000384.3(APOB):c.905-16A>C	rs12720810	0.00172
NM_000384.3(APOB):c.11819C>T (p.Thr3940Met)	rs72654416	0.00161
NM_000384.3(APOB):c.9294C>T (p.Tyr3098=)	rs145777339	0.00139
NM_000384.3(APOB):c.12699G>A (p.Ser4233=)	rs56675344	0.00136
NM_000384.3(APOB):c.2068-4T>A	rs41291161	0.00108
NM_000384.3(APOB):c.7612C>T (p.Leu2538=)	rs72653093	0.00108
NM_000384.3(APOB):c.4838G>C (p.Ser1613Thr)	rs61742247	0.00093
NM_000384.3(APOB):c.13449G>A (p.Ala4483=)	rs138421941	0.00092
NM_000384.3(APOB):c.3509-11C>T	rs200768300	0.00091
NM_000384.3(APOB):c.12903C>T (p.Asp4301=)	rs200145506	0.00090
NM_000384.3(APOB):c.13102C>G (p.Gln4368Glu)	rs72654424	0.00080
NM_000384.3(APOB):c.4178C>T (p.Ala1393Val)	rs143282164	0.00073
NM_000384.3(APOB):c.3740A>G (p.Tyr1247Cys)	rs61741164	0.00071
NM_000384.3(APOB):c.895T>G (p.Phe299Val)	rs72653060	0.00051
NM_000384.3(APOB):c.7152T>C (p.Val2384=)	rs72653090	0.00041
NM_000384.3(APOB):c.8912A>C (p.Asn2971Thr)	rs72653098	0.00026
NM_000384.3(APOB):c.10476T>A (p.Ile3492=)	rs139929439	0.00021
NM_000384.3(APOB):c.11244G>A (p.Thr3748=)	rs72654406	0.00020
NM_000384.3(APOB):c.11354C>T (p.Thr3785Ile)	rs143710616	0.00019
NM_000384.3(APOB):c.12016G>A (p.Val4006Ile)	rs183117027	0.00019
NM_000384.3(APOB):c.10385A>G (p.Tyr3462Cys)	rs200305144	0.00014
NM_000384.3(APOB):c.244C>T (p.Leu82=)	rs201658954	0.00014
NM_000384.3(APOB):c.11542G>A (p.Ala3848Thr)	rs61743512	0.00012
NM_000384.3(APOB):c.8877G>A (p.Leu2959=)	rs765899256	0.00012
NM_000384.3(APOB):c.3471T>C (p.Tyr1157=)	rs201128198	0.00009
NM_000384.3(APOB):c.12318A>G (p.Arg4106=)	rs375795401	0.00008
NM_000384.3(APOB):c.5622G>A (p.Gly1874=)	rs144849403	0.00008
NM_000384.3(APOB):c.2938G>A (p.Ala980Thr)	rs369310292	0.00007
NM_000384.3(APOB):c.7998A>G (p.Val2666=)	rs1042006	0.00007
NM_000384.3(APOB):c.9491C>T (p.Thr3164Met)	rs143269114	0.00007
NM_000384.3(APOB):c.10579C>T (p.Arg3527Trp)	rs144467873	0.00006
NM_000384.3(APOB):c.11934C>T (p.Ile3978=)	rs539824713	0.00006
NM_000384.3(APOB):c.4157G>A (p.Arg1386Gln)	rs145007060	0.00006
NM_000384.3(APOB):c.8599C>T (p.Leu2867=)	rs149430596	0.00006
NM_000384.3(APOB):c.3594C>T (p.Ser1198=)	rs138243977	0.00005
NM_000384.3(APOB):c.1061A>G (p.Glu354Gly)	rs149227065	0.00004
NM_000384.3(APOB):c.11303T>C (p.Ile3768Thr)	rs376825639	0.00004
NM_000384.3(APOB):c.1400C>G (p.Ala467Gly)	rs376602710	0.00004
NM_000384.3(APOB):c.2047G>T (p.Ala683Ser)	rs761947252	0.00004
NM_000384.3(APOB):c.5022G>A (p.Glu1674=)	rs367718499	0.00004
NM_000384.3(APOB):c.5705C>T (p.Pro1902Leu)	rs368848646	0.00004
NM_000384.3(APOB):c.6201C>T (p.His2067=)	rs143222685	0.00004
NM_000384.3(APOB):c.10056C>A (p.Thr3352=)	rs369022661	0.00003
NM_000384.3(APOB):c.12021C>A (p.Gly4007=)	rs145498491	0.00003
NM_000384.3(APOB):c.3034G>A (p.Glu1012Lys)	rs575505383	0.00003
NM_000384.3(APOB):c.5028C>T (p.Gly1676=)	rs201446451	0.00003
NM_000384.3(APOB):c.543C>T (p.Thr181=)	rs778023021	0.00003
NM_000384.3(APOB):c.6513A>G (p.Leu2171=)	rs547853968	0.00003
NM_000384.3(APOB):c.13399G>A (p.Ala4467Thr)	rs1407600482	0.00001
NM_000384.3(APOB):c.2556A>C (p.Gly852=)	rs778199079	0.00001
NM_000384.3(APOB):c.5617G>A (p.Ala1873Thr)	rs750451480	0.00001
NM_000384.3(APOB):c.6390T>C (p.Asn2130=)	rs570798466	0.00001
NM_000384.3(APOB):c.819-10T>G	rs749762235	0.00001
NM_000384.3(APOB):c.9501A>G (p.Gln3167=)	rs533171453	0.00001
NM_000384.3(APOB):c.10186G>A (p.Ala3396Thr)	rs1553383017
NM_000384.3(APOB):c.10580G>A (p.Arg3527Gln)
NM_000384.3(APOB):c.10701G>T (p.Thr3567=)	rs12713558
NM_000384.3(APOB):c.10913G>A (p.Arg3638Gln)
NM_000384.3(APOB):c.11401T>A (p.Ser3801Thr)
NM_000384.3(APOB):c.11477C>T (p.Thr3826Met)
NM_000384.3(APOB):c.11761G>A (p.Val3921Ile)
NM_000384.3(APOB):c.12053A>G (p.Asp4018Gly)	rs771555558
NM_000384.3(APOB):c.12404G>T (p.Ser4135Ile)
NM_000384.3(APOB):c.12460G>T (p.Glu4154Ter)
NM_000384.3(APOB):c.12541G>A (p.Glu4181Lys)
NM_000384.3(APOB):c.12697T>A (p.Ser4233Thr)
NM_000384.3(APOB):c.12809G>C (p.Arg4270Thr)
NM_000384.3(APOB):c.13013G>A (p.Ser4338Asn)
NM_000384.3(APOB):c.13028_13029del (p.Tyr4343fs)	rs760832994
NM_000384.3(APOB):c.13070A>G (p.His4357Arg)
NM_000384.3(APOB):c.1310G>A (p.Arg437His)
NM_000384.3(APOB):c.13441G>A (p.Ala4481Thr)
NM_000384.3(APOB):c.13451C>T (p.Thr4484Met)
NM_000384.3(APOB):c.1468C>T (p.Arg490Trp)	rs771541567
NM_000384.3(APOB):c.1594C>T (p.Arg532Trp)
NM_000384.3(APOB):c.1853C>T (p.Ala618Val)
NM_000384.3(APOB):c.2188G>A (p.Val730Ile)
NM_000384.3(APOB):c.2863C>T (p.Pro955Ser)
NM_000384.3(APOB):c.293C>T (p.Thr98Ile)
NM_000384.3(APOB):c.3000-1G>A
NM_000384.3(APOB):c.307T>C (p.Tyr103His)
NM_000384.3(APOB):c.3122-6G>A	rs72653071
NM_000384.3(APOB):c.3122-6G>T	rs72653071
NM_000384.3(APOB):c.3201G>A (p.Pro1067=)	rs200281277
NM_000384.3(APOB):c.3337G>C (p.Asp1113His)
NM_000384.3(APOB):c.3427C>T (p.Pro1143Ser)
NM_000384.3(APOB):c.444T>C (p.Asp148=)
NM_000384.3(APOB):c.5066G>A (p.Arg1689His)
NM_000384.3(APOB):c.5163C>T (p.Val1721=)	rs536182427
NM_000384.3(APOB):c.5741A>G (p.Asn1914Ser)
NM_000384.3(APOB):c.5768A>G (p.His1923Arg)
NM_000384.3(APOB):c.5815G>A (p.Ala1939Thr)
NM_000384.3(APOB):c.5941T>G (p.Trp1981Gly)
NM_000384.3(APOB):c.6057A>G (p.Leu2019=)
NM_000384.3(APOB):c.6063C>G (p.Asp2021Glu)	rs556582055
NM_000384.3(APOB):c.6231G>A (p.Leu2077=)
NM_000384.3(APOB):c.6636TGA[1] (p.Asp2213del)	rs541497967
NM_000384.3(APOB):c.677C>T (p.Ala226Val)
NM_000384.3(APOB):c.693+7C>T
NM_000384.3(APOB):c.6936_6937inv (p.Ile2313Val)
NM_000384.3(APOB):c.7367C>A (p.Ala2456Asp)
NM_000384.3(APOB):c.7832C>G (p.Thr2611Ser)	rs138790085
NM_000384.3(APOB):c.8216C>T (p.Pro2739Leu)
NM_000384.3(APOB):c.8226G>A (p.Gln2742=)	rs376773500
NM_000384.3(APOB):c.8363G>T (p.Gly2788Val)	rs534116066
NM_000384.3(APOB):c.8529G>T (p.Met2843Ile)
NM_000384.3(APOB):c.8757A>G (p.Ile2919Met)
NM_000384.3(APOB):c.9204A>C (p.Ile3068=)
NM_000384.3(APOB):c.9242G>A (p.Ser3081Asn)	rs72653100
NM_000384.3(APOB):c.9242G>C (p.Ser3081Thr)	rs72653100
NM_000384.3(APOB):c.9384T>A (p.Ile3128=)
NM_000384.3(APOB):c.9502T>A (p.Ser3168Thr)	rs761382742
NM_000384.3(APOB):c.9715C>T (p.His3239Tyr)	rs755547544
NM_000384.3(APOB):c.9835A>G (p.Ser3279Gly)
NM_000384.3(APOB):c.9880T>C (p.Ser3294Pro)

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