ClinVar Miner

List of variants in gene WRN reported by PreventionGenetics, part of Exact Sciences

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Gene type:
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Total variants: 62
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HGVS dbSNP gnomAD frequency
NM_000553.6(WRN):c.513C>T (p.Cys171=) rs1800389 0.66802
NM_000553.6(WRN):c.3222G>T (p.Leu1074Phe) rs1801195 0.46398
NM_000553.6(WRN):c.3138+7G>A rs2737335 0.46283
NM_000553.6(WRN):c.2361G>T (p.Leu787=) rs1800392 0.44630
NM_000553.6(WRN):c.3138+6C>T rs3024239 0.39769
NM_000553.6(WRN):c.4083C>T (p.Ser1361=) rs1801196 0.28751
NM_000553.6(WRN):c.4099T>C (p.Cys1367Arg) rs1346044 0.22492
NM_000553.6(WRN):c.1577-3C>A rs3087409 0.07869
NM_000553.6(WRN):c.340G>A (p.Val114Ile) rs2230009 0.07797
NM_000553.6(WRN):c.1161G>A (p.Met387Ile) rs1800391 0.06046
NM_000553.6(WRN):c.355+20A>T rs4987239 0.04393
NM_000553.6(WRN):c.3384-3T>C rs3087424 0.01376
NM_000553.6(WRN):c.1577-17T>G rs145080962 0.00363
NM_000553.6(WRN):c.1717A>G (p.Thr573Ala) rs150148567 0.00169
NM_000553.6(WRN):c.1350+3A>G rs182813211 0.00108
NM_000553.6(WRN):c.107G>A (p.Arg36Gln) rs34084741 0.00091
NM_000553.6(WRN):c.2059T>G (p.Leu687Val) rs185468906 0.00091
NM_000553.6(WRN):c.720T>G (p.Asn240Lys) rs148229804 0.00085
NM_000553.6(WRN):c.3059G>A (p.Arg1020His) rs115298665 0.00074
NM_000553.6(WRN):c.1027G>A (p.Glu343Lys) rs11574222 0.00072
NM_000553.6(WRN):c.3422C>T (p.Ser1141Leu) rs139323683 0.00052
NM_000553.6(WRN):c.2571T>C (p.Arg857=) rs3087432 0.00029
NM_000553.6(WRN):c.1909C>T (p.Arg637Trp) rs148286708 0.00028
NM_000553.6(WRN):c.3259A>G (p.Lys1087Glu) rs374154973 0.00028
NM_000553.6(WRN):c.326G>A (p.Cys109Tyr) rs142346721 0.00025
NM_000553.6(WRN):c.3101A>T (p.Tyr1034Phe) rs200370409 0.00024
NM_000553.6(WRN):c.1531G>C (p.Asp511His) rs368413625 0.00018
NM_000553.6(WRN):c.2131C>T (p.Arg711Trp) rs34560788 0.00017
NM_000553.6(WRN):c.2067C>T (p.Ser689=) rs191757062 0.00010
NM_000553.6(WRN):c.3819+5G>C rs770289356 0.00008
NM_000553.6(WRN):c.1302G>A (p.Thr434=) rs374140086 0.00007
NM_000553.6(WRN):c.1451G>T (p.Ser484Ile) rs776008000 0.00006
NM_000553.6(WRN):c.1505G>T (p.Gly502Val) rs201172985 0.00005
NM_000553.6(WRN):c.3588A>G (p.Glu1196=) rs61761624 0.00005
NM_000553.6(WRN):c.1830-3T>C rs1241338285 0.00004
NM_000553.6(WRN):c.2274-7T>C rs369709714 0.00004
NM_000553.6(WRN):c.3021C>A (p.Gly1007=) rs367867308 0.00004
NM_000553.6(WRN):c.2342C>T (p.Thr781Ile) rs17847568 0.00003
NM_000553.6(WRN):c.654+4C>T rs769275170 0.00003
NM_000553.6(WRN):c.1378G>A (p.Asp460Asn) rs556958354 0.00002
NM_000553.6(WRN):c.747C>A (p.Asp249Glu) rs374142752 0.00002
NM_000553.6(WRN):c.1920C>T (p.Tyr640=) rs765756226 0.00001
NM_000553.6(WRN):c.2004T>C (p.Asp668=) rs575593855 0.00001
NM_000553.6(WRN):c.2088+6C>T rs886062888 0.00001
NM_000553.6(WRN):c.2443A>G (p.Ile815Val) rs974712158 0.00001
NM_000553.6(WRN):c.3205T>C (p.Leu1069=) rs369044109 0.00001
NM_000553.6(WRN):c.3801A>G (p.Gln1267=) rs779902531 0.00001
NM_000553.6(WRN):c.673C>T (p.Arg225Ter) rs370324188 0.00001
NM_000553.6(WRN):c.1351-9T>C rs1427993542
NM_000553.6(WRN):c.1383G>A (p.Thr461=) rs542602723
NM_000553.6(WRN):c.1518AGA[4] (p.Glu510del) rs781777438
NM_000553.6(WRN):c.1982-5del rs397723919
NM_000553.6(WRN):c.2019T>C (p.Ile673=)
NM_000553.6(WRN):c.2031G>C (p.Gly677=)
NM_000553.6(WRN):c.2416A>G (p.Ile806Val) rs200935416
NM_000553.6(WRN):c.3234-130T>C rs2725364
NM_000553.6(WRN):c.3244del (p.Val1082fs) rs745905108
NM_000553.6(WRN):c.3573-31TTG[6]
NM_000553.6(WRN):c.3573-31TTG[8]
NM_000553.6(WRN):c.3983-12dup rs368931913
NM_000553.6(WRN):c.725-9del rs543830844
NM_000553.6(WRN):c.956C>T (p.Ser319Phe) rs1001988186

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