ClinVar Miner

List of variants in gene combination DHFR, MSH3 reported by GeneDx

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Gene type:
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Total variants: 45
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HGVS dbSNP gnomAD frequency
NM_000791.4(DHFR):c.-473T>C rs1650697 0.80068
NM_002439.5(MSH3):c.-35A>G rs1105524 0.63625
NM_002439.5(MSH3):c.-50C>T rs2250063 0.25491
NC_000005.10:g.80654584C>T rs10168 0.25445
NM_000791.4(DHFR):c.-400A>G rs2405875 0.02618
NM_000791.4(DHFR):c.-416C>G rs2001675 0.00949
NM_000791.4(DHFR):c.-259C>T rs6151597 0.00699
NM_000791.4(DHFR):c.-367T>C rs141080879 0.00183
NM_000791.4(DHFR):c.-419C>G rs1574197 0.00128
NM_000791.4(DHFR):c.-197G>A rs534679562 0.00034
NM_002439.5(MSH3):c.16C>T (p.Pro6Ser) rs374904719 0.00016
NM_002439.5(MSH3):c.130G>C (p.Ala44Pro) rs756684854 0.00002
NM_000791.4(DHFR):c.-239T>A rs775714088 0.00001
NM_000791.4(DHFR):c.-319G>A rs749586225 0.00001
NM_002439.5(MSH3):c.124G>T (p.Gly42Cys) rs756968089 0.00001
NM_002439.5(MSH3):c.128C>T (p.Ala43Val) rs928378977 0.00001
NM_002439.5(MSH3):c.22T>C (p.Ser8Pro) rs1313510221 0.00001
NM_002439.5(MSH3):c.237+2T>C rs1480047980 0.00001
NC_000005.10:g.80654344_80654345insTGGCGCGTCCCGCCCAGGT rs70991108
NC_000005.10:g.80654576del rs151182735
NM_000791.4(DHFR):c.-406CGCTGCAGC[3] rs758595508
NM_000791.4(DHFR):c.-417_-416insGCGCTGCGGCCGCTGCGG rs758718643
NM_000791.4(DHFR):c.-418GGCCGCTGC[1] rs758960105
NM_000791.4(DHFR):c.-418GGCCGCTGC[3] rs758960105
NM_000791.4(DHFR):c.-425_-417dup rs1554066076
NM_000791.4(DHFR):c.-437GGGGCGCTG[1] rs60484572
NM_000791.4(DHFR):c.-437GGGGCGCTG[4] rs60484572
NM_000791.4(DHFR):c.-437GGGGCGCTG[5] rs60484572
NM_000791.4(DHFR):c.-437GGGGCGCTG[6] rs60484572
NM_000791.4(DHFR):c.-442_-434del rs3045983
NM_002439.5(MSH3):c.-39C>T rs1105525
NM_002439.5(MSH3):c.15G>T (p.Lys5Asn) rs563338833
NM_002439.5(MSH3):c.162_179del (p.Ala57_Ala62del) rs201874762
NM_002439.5(MSH3):c.166_167insAGGCCGCAGCGGCCGCAG (p.Ala55_Ala56insGluAlaAlaAlaAlaAla)
NM_002439.5(MSH3):c.166_167insGGGCCGCAG (p.Ala55_Ala56insGlyAlaAla) rs1554066045
NM_002439.5(MSH3):c.178_179insTCGCAGCGC (p.Ala60delinsValAlaAlaPro)
NM_002439.5(MSH3):c.190C>T (p.Pro64Ser)
NM_002439.5(MSH3):c.208G>C (p.Ala70Pro) rs765698219
NM_002439.5(MSH3):c.211_230dup (p.His78fs) rs1749219575
NM_002439.5(MSH3):c.215C>T (p.Pro72Leu) rs1404800640
NM_002439.5(MSH3):c.227CGC[3] (p.Pro77_His78insPro) rs1490449810
NM_002439.5(MSH3):c.235A>T (p.Ile79Leu) rs1650697
NM_002439.5(MSH3):c.23C>T (p.Ser8Leu) rs2546709784
NM_002439.5(MSH3):c.59G>A (p.Arg20Lys) rs1580537787
NM_002439.5(MSH3):c.67G>A (p.Val23Ile) rs1353893324

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