List of variants in gene FGFR1 reported as uncertain significance by GeneDx

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 103

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HGVS	dbSNP	gnomAD frequency
NM_023110.3(FGFR1):c.1269G>A (p.Leu423=)	rs144131616	0.00016
NM_023110.3(FGFR1):c.231C>G (p.Asn77Lys)	rs767195580	0.00010
NM_023110.3(FGFR1):c.1520G>A (p.Arg507His)	rs369356672	0.00009
NM_023110.3(FGFR1):c.1408C>T (p.Arg470Cys)	rs781310679	0.00007
NM_023110.3(FGFR1):c.2428C>T (p.His810Tyr)	rs759376422	0.00004
NM_023110.3(FGFR1):c.378G>T (p.Glu126Asp)	rs758823379	0.00004
NM_023110.3(FGFR1):c.56G>C (p.Cys19Ser)	rs759243486	0.00004
NM_023110.3(FGFR1):c.74C>T (p.Pro25Leu)	rs149206728	0.00004
NM_023110.3(FGFR1):c.2049-12G>A	rs563601371	0.00003
NM_023110.3(FGFR1):c.1139A>G (p.Tyr380Cys)	rs777103792	0.00002
NM_023110.3(FGFR1):c.193A>C (p.Asn65His)	rs768919123	0.00002
NM_023110.3(FGFR1):c.2426G>A (p.Arg809Gln)	rs771680156	0.00002
NM_023110.3(FGFR1):c.243C>T (p.Ile81=)	rs764340351	0.00002
NM_023110.3(FGFR1):c.451G>A (p.Val151Ile)	rs762665767	0.00002
NM_023110.3(FGFR1):c.83C>T (p.Pro28Leu)	rs145434725	0.00002
NM_023110.3(FGFR1):c.1078G>A (p.Glu360Lys)	rs982371464	0.00001
NM_023110.3(FGFR1):c.128T>G (p.Phe43Cys)	rs1085307493	0.00001
NM_023110.3(FGFR1):c.1333C>T (p.Arg445Trp)	rs781608303	0.00001
NM_023110.3(FGFR1):c.1447C>T (p.Pro483Ser)	rs397515444	0.00001
NM_023110.3(FGFR1):c.1558G>A (p.Ala520Thr)	rs749758370	0.00001
NM_023110.3(FGFR1):c.1616G>A (p.Gly539Glu)	rs780953869	0.00001
NM_023110.3(FGFR1):c.166C>T (p.Arg56Trp)	rs1034848904	0.00001
NM_023110.3(FGFR1):c.178G>A (p.Asp60Asn)	rs1586379709	0.00001
NM_023110.3(FGFR1):c.2023C>T (p.Arg675Trp)	rs375611478	0.00001
NM_023110.3(FGFR1):c.2272G>A (p.Val758Met)	rs527606454	0.00001
NM_023110.3(FGFR1):c.2370_2371del (p.Glu792fs)	rs767698667	0.00001
NM_023110.3(FGFR1):c.277C>T (p.Pro93Ser)	rs372511659	0.00001
NM_023110.3(FGFR1):c.374C>T (p.Ser125Leu)	rs121913473	0.00001
NM_023110.3(FGFR1):c.386A>C (p.Asp129Ala)	rs765615419	0.00001
NM_023110.3(FGFR1):c.442C>T (p.Arg148Cys)	rs780153672	0.00001
NM_023110.3(FGFR1):c.443G>A (p.Arg148His)	rs515726222	0.00001
NM_023110.3(FGFR1):c.448C>T (p.Pro150Ser)	rs746094709	0.00001
NM_023110.3(FGFR1):c.646A>G (p.Ile216Val)	rs763771933	0.00001
NM_023110.3(FGFR1):c.68C>T (p.Pro23Leu)	rs143341876	0.00001
NM_023110.3(FGFR1):c.8G>A (p.Ser3Asn)	rs751651299	0.00001
NM_023110.3(FGFR1):c.-78A>T	rs1554594314
NM_023110.3(FGFR1):c.1028C>T (p.Ala343Val)	rs1818935081
NM_023110.3(FGFR1):c.1070C>G (p.Thr357Ser)
NM_023110.3(FGFR1):c.1078G>C (p.Glu360Gln)	rs982371464
NM_023110.3(FGFR1):c.1082-3C>A
NM_023110.3(FGFR1):c.1082C>A (p.Ala361Asp)
NM_023110.3(FGFR1):c.1097C>T (p.Pro366Leu)	rs121909641
NM_023110.3(FGFR1):c.1120T>G (p.Tyr374Asp)	rs2150713606
NM_023110.3(FGFR1):c.1279G>A (p.Val427Ile)	rs2150704224
NM_023110.3(FGFR1):c.1285G>A (p.Val429Met)
NM_023110.3(FGFR1):c.1323_1324delinsGG (p.Leu442Val)	rs2150677143
NM_023110.3(FGFR1):c.1334G>A (p.Arg445Gln)
NM_023110.3(FGFR1):c.1343G>A (p.Arg448Gln)	rs758138124
NM_023110.3(FGFR1):c.1349C>T (p.Ser450Phe)	rs2150675272
NM_023110.3(FGFR1):c.1352C>A (p.Ser451Tyr)
NM_023110.3(FGFR1):c.1417C>G (p.Leu473Val)	rs780577173
NM_023110.3(FGFR1):c.1423C>T (p.Arg475Trp)	rs2150669975
NM_023110.3(FGFR1):c.148C>G (p.Leu50Val)	rs1822318253
NM_023110.3(FGFR1):c.1537G>A (p.Val513Met)	rs1085307722
NM_023110.3(FGFR1):c.1660G>A (p.Asp554Asn)	rs1057524808
NM_023110.3(FGFR1):c.1700G>T (p.Gly567Val)	rs2150590532
NM_023110.3(FGFR1):c.1709G>A (p.Arg570Gln)
NM_023110.3(FGFR1):c.1723_1731del (p.Ala575_Arg577del)	rs1554549926
NM_023110.3(FGFR1):c.1727G>A (p.Arg576Gln)	rs1482868825
NM_023110.3(FGFR1):c.172C>T (p.Arg58Trp)	rs1162148796
NM_023110.3(FGFR1):c.1838A>G (p.Tyr613Cys)	rs1064793124
NM_023110.3(FGFR1):c.1900G>A (p.Asp634Asn)	rs2150563531
NM_023110.3(FGFR1):c.1904A>T (p.Asn635Ile)	rs544967630
NM_023110.3(FGFR1):c.1907T>A (p.Val636Glu)	rs2150563316
NM_023110.3(FGFR1):c.1982G>A (p.Arg661Gln)	rs1257312391
NM_023110.3(FGFR1):c.1990G>A (p.Val664Met)	rs1057518620
NM_023110.3(FGFR1):c.2024G>C (p.Arg675Pro)	rs771078736
NM_023110.3(FGFR1):c.2032A>G (p.Thr678Ala)
NM_023110.3(FGFR1):c.2057T>C (p.Phe686Ser)
NM_023110.3(FGFR1):c.2090G>T (p.Gly697Val)
NM_023110.3(FGFR1):c.2107G>C (p.Gly703Arg)	rs768957161
NM_023110.3(FGFR1):c.2153G>A (p.Arg718His)	rs1415925468
NM_023110.3(FGFR1):c.2184G>C (p.Glu728Asp)	rs2150530086
NM_023110.3(FGFR1):c.2208C>G (p.Cys736Trp)
NM_023110.3(FGFR1):c.2267G>T (p.Arg756Leu)	rs374473310
NM_023110.3(FGFR1):c.2302G>C (p.Asp768His)	rs121909644
NM_023110.3(FGFR1):c.2314C>A (p.Pro772Thr)
NM_023110.3(FGFR1):c.2323C>G (p.Gln775Glu)	rs1232665126
NM_023110.3(FGFR1):c.232C>T (p.Arg78Cys)	rs1554570706
NM_023110.3(FGFR1):c.2359A>G (p.Thr787Ala)
NM_023110.3(FGFR1):c.2368T>C (p.Ser790Pro)	rs2150508439
NM_023110.3(FGFR1):c.2390C>T (p.Ser797Phe)	rs2150507302
NM_023110.3(FGFR1):c.2391_2392del (p.Ser797_His798insTer)
NM_023110.3(FGFR1):c.2392C>G (p.His798Asp)
NM_023110.3(FGFR1):c.2414C>A (p.Pro805His)	rs2150506099
NM_023110.3(FGFR1):c.2455C>T (p.Leu819Phe)
NM_023110.3(FGFR1):c.245C>G (p.Thr82Arg)
NM_023110.3(FGFR1):c.2460del (p.Lys820fs)
NM_023110.3(FGFR1):c.303C>G (p.Cys101Trp)	rs142638017
NM_023110.3(FGFR1):c.381TGA[7] (p.Asp133dup)	rs138489552
NM_023110.3(FGFR1):c.397_399dup (p.Asp133_Ser134insAsp)
NM_023110.3(FGFR1):c.421A>G (p.Thr141Ala)	rs1315551279
NM_023110.3(FGFR1):c.443G>C (p.Arg148Pro)
NM_023110.3(FGFR1):c.449-6G>A
NM_023110.3(FGFR1):c.449C>A (p.Pro150His)
NM_023110.3(FGFR1):c.506C>T (p.Pro169Leu)	rs1413642890
NM_023110.3(FGFR1):c.535C>T (p.Pro179Ser)	rs2150914279
NM_023110.3(FGFR1):c.61G>A (p.Ala21Thr)	rs1383262590
NM_023110.3(FGFR1):c.673A>G (p.Lys225Glu)	rs1820696854
NM_023110.3(FGFR1):c.677G>A (p.Gly226Asp)	rs1246231808
NM_023110.3(FGFR1):c.820G>C (p.Glu274Gln)	rs1443012936
NM_023110.3(FGFR1):c.92-19G>A	rs753723806
NM_023110.3(FGFR1):c.936+3A>C	rs1554561775

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