ClinVar Miner

List of variants in gene SPINK5 reported as benign by GeneDx

Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:
Total variants: 202
Download table as spreadsheet
HGVS dbSNP gnomAD frequency
NM_006846.4(SPINK5):c.210-295A>G rs1156807 0.99281
NM_006846.4(SPINK5):c.2313+228C>T rs6872326 0.79091
NM_006846.4(SPINK5):c.2313+142C>A rs9325075 0.79047
NM_006846.4(SPINK5):c.2313+48G>A rs9325074 0.79044
NM_006846.4(SPINK5):c.2666+297A>C rs1422993 0.78192
NM_006846.4(SPINK5):c.882+159G>A rs62388364 0.74556
NM_006846.4(SPINK5):c.209+234A>G rs10073775 0.74377
NM_006846.4(SPINK5):c.82-31A>G rs1423001 0.74351
NM_006846.4(SPINK5):c.1888-145T>G rs3815737 0.74209
NM_006846.4(SPINK5):c.209+72C>A rs3752676 0.70739
NM_006846.4(SPINK5):c.1888-54G>A rs3815735 0.69656
NM_006846.4(SPINK5):c.81+54G>A rs9325061 0.69401
NM_006846.4(SPINK5):c.81+88C>G rs1609851 0.69397
NM_006846.4(SPINK5):c.283-339T>C rs1363724 0.67386
NM_006846.4(SPINK5):c.81+189A>G rs1007979 0.64299
NM_006846.4(SPINK5):c.1659C>T (p.Val553=) rs2303071 0.58781
NM_006846.4(SPINK5):c.56-125A>G rs2287772 0.58539
NM_006846.4(SPINK5):c.2868-169A>G rs11168029 0.56316
NM_006846.4(SPINK5):c.2666+233G>A rs1422994 0.56275
NM_006846.4(SPINK5):c.2965-46T>C rs6895434 0.56266
NM_006846.4(SPINK5):c.3009T>C (p.Gly1003=) rs2400478 0.56263
NM_006846.4(SPINK5):c.2740-59G>A rs2112767 0.56261
NM_006846.4(SPINK5):c.2739+219T>A rs2052535 0.56260
NM_006846.4(SPINK5):c.2964+249G>A rs2303072 0.56252
NM_006846.4(SPINK5):c.2739+157T>G rs2052536 0.56247
NM_006846.4(SPINK5):c.2964+225A>G rs2303073 0.56240
NM_006846.4(SPINK5):c.2241-26T>C rs3764926 0.56233
NM_006846.4(SPINK5):c.2241-160G>C rs3764927 0.54178
NM_006846.4(SPINK5):c.2132G>A (p.Arg711Gln) rs3777134 0.54171
NM_006846.4(SPINK5):c.2113-227T>G rs3777136 0.54166
NM_006846.4(SPINK5):c.2412C>T (p.Gly804=) rs33920397 0.54161
NM_006846.4(SPINK5):c.2240+165A>G rs3764928 0.54154
NM_006846.4(SPINK5):c.2358C>T (p.Leu786=) rs17704908 0.54150
NM_006846.4(SPINK5):c.2113-68T>C rs3777135 0.54145
NM_006846.4(SPINK5):c.2313+51G>A rs12518996 0.54077
NM_006846.4(SPINK5):c.1888-134C>T rs3815736 0.53024
NM_006846.4(SPINK5):c.882+45_882+46insT rs76839946 0.51324
NM_006846.4(SPINK5):c.2112+278G>A rs2052532 0.50963
NM_006846.4(SPINK5):c.2740-170G>A rs3764930 0.50854
NM_006846.4(SPINK5):c.2113-270C>T rs3777137 0.50847
NM_006846.4(SPINK5):c.795-228C>A rs6870820 0.50406
NM_006846.4(SPINK5):c.283-337C>T rs1363725 0.48975
NM_006846.4(SPINK5):c.1888-92C>T rs35043219 0.48835
NM_006846.4(SPINK5):c.210-260C>T rs7445392 0.46529
NM_006846.4(SPINK5):c.1092+172A>G rs35661442 0.46283
NM_006846.4(SPINK5):c.474+66C>G rs7711953 0.46092
NM_006846.4(SPINK5):c.882+238G>A rs35803917 0.45984
NM_006846.4(SPINK5):c.882+20A>G rs11958432 0.45982
NM_006846.4(SPINK5):c.883-170A>G rs11168019 0.45981
NM_006846.4(SPINK5):c.882+122G>A rs11948406 0.45944
NM_006846.4(SPINK5):c.882+141A>G rs62388363 0.45400
NM_006846.4(SPINK5):c.1011-12C>T rs1422991 0.45033
NM_006846.4(SPINK5):c.1092+159A>G rs11168022 0.44726
NM_006846.4(SPINK5):c.1092+103C>A rs11168021 0.44349
NM_006846.4(SPINK5):c.1389A>G (p.Gly463=) rs6896303 0.44173
NM_006846.4(SPINK5):c.1302+19G>A rs2303068 0.44163
NM_006846.4(SPINK5):c.1092+238T>A rs13172395 0.44161
NM_006846.4(SPINK5):c.1221-50G>A rs2303066 0.44154
NM_006846.4(SPINK5):c.1258A>G (p.Lys420Glu) rs2303067 0.44148
NM_006846.4(SPINK5):c.1093-26C>T rs2303061 0.44132
NM_006846.4(SPINK5):c.1103G>A (p.Ser368Asn) rs2303063 0.44127
NM_006846.4(SPINK5):c.1221-241dup rs11380717 0.44125
NM_006846.4(SPINK5):c.*44T>C rs4349706 0.43753
NM_006846.4(SPINK5):c.*208C>G rs3088193 0.43751
NM_006846.4(SPINK5):c.794+313A>T rs7725816 0.29266
NM_006846.4(SPINK5):c.1480-241C>T rs1422987 0.29128
NM_006846.4(SPINK5):c.1156G>A (p.Asp386Asn) rs2303064 0.24722
NM_006846.4(SPINK5):c.2739+139G>C rs2303075 0.21911
NM_006846.4(SPINK5):c.2740-381A>G rs3764931 0.21891
NM_006846.4(SPINK5):c.2314-146A>C rs6580523 0.21245
NM_006846.4(SPINK5):c.1820+74T>C rs2287768 0.16402
NM_006846.4(SPINK5):c.1607+274G>A rs11953763 0.16368
NM_006846.4(SPINK5):c.1692+254A>G rs17704764 0.15864
NM_006846.4(SPINK5):c.1693-32C>T rs2287769 0.14805
NM_006846.4(SPINK5):c.1887+182G>T rs41291433 0.14801
NM_006846.4(SPINK5):c.1820+268T>C rs6887442 0.14797
NM_006846.4(SPINK5):c.1887+165C>A rs55816145 0.14797
NM_006846.4(SPINK5):c.1820+119C>T rs2287766 0.14795
NM_006846.4(SPINK5):c.1820+94A>G rs2287767 0.14793
NM_006846.4(SPINK5):c.1820+166A>T rs6883062 0.14791
NM_006846.4(SPINK5):c.1693-138A>G rs3815740 0.14790
NM_006846.4(SPINK5):c.1693-113A>G rs2287770 0.14786
NM_006846.4(SPINK5):c.1887+221G>C rs73794675 0.14755
NM_006846.4(SPINK5):c.1887+203C>A rs201488506 0.14748
NM_006846.4(SPINK5):c.1887+223A>G rs73794676 0.14746
NM_006846.4(SPINK5):c.1887+204A>G rs199893956 0.14745
NM_006846.4(SPINK5):c.1693-304A>G rs73794671 0.14736
NM_006846.4(SPINK5):c.1693-300T>C rs73794672 0.14730
NM_006846.4(SPINK5):c.1821-142A>G rs79688803 0.14702
NM_006846.4(SPINK5):c.1821-143G>A rs77701346 0.14699
NM_006846.4(SPINK5):c.1821-241C>T rs113469247 0.14695
NM_006846.4(SPINK5):c.1821-210T>C rs150897404 0.14654
NM_006846.4(SPINK5):c.1821-217A>G rs113717952 0.14632
NM_006846.4(SPINK5):c.1821-208A>G rs138483982 0.14597
NM_006846.4(SPINK5):c.1692+175T>C rs3815741 0.14093
NM_006846.4(SPINK5):c.1692+228del rs113070270 0.14086
NM_006846.4(SPINK5):c.2539-321_2539-320del rs1491016312 0.13465
NM_006846.4(SPINK5):c.1011-223C>G rs35332271 0.11488
NM_006846.4(SPINK5):c.2475G>T (p.Glu825Asp) rs2303070 0.10250
NM_006846.4(SPINK5):c.*330T>C rs72660265 0.09913
NM_006846.4(SPINK5):c.3096-182C>T rs60763631 0.09840
NM_006846.4(SPINK5):c.1888-325A>T rs3815738 0.09821
NM_006846.4(SPINK5):c.2539-321_2539-312del rs1269887698 0.09405
NM_006846.4(SPINK5):c.883-246A>G rs9791022 0.08998
NM_006846.4(SPINK5):c.81+165C>T rs78365969 0.07848
NM_006846.4(SPINK5):c.2539-78A>G rs58409150 0.07326
NM_006846.4(SPINK5):c.1607+52_1607+53del rs58761763 0.06963
NM_006846.4(SPINK5):c.1093-209G>C rs17107730 0.06609
NM_006846.4(SPINK5):c.2016-295C>G rs10056793 0.06162
NM_006846.4(SPINK5):c.2314-322G>A rs11745768 0.05914
NM_006846.4(SPINK5):c.81+77T>C rs2287771 0.05470
NM_006846.4(SPINK5):c.1344G>A (p.Arg448=) rs17107741 0.05403
NM_006846.4(SPINK5):c.410+247A>C rs72660253 0.05339
NM_006846.4(SPINK5):c.81+189_81+190insTG rs1561669928 0.04978
NM_006846.4(SPINK5):c.2015+316T>C rs6863918 0.04945
NM_006846.4(SPINK5):c.-61A>C rs74572734 0.04900
NM_006846.4(SPINK5):c.209+15C>T rs3752677 0.04511
NM_006846.4(SPINK5):c.2661C>G (p.Ser887Arg) rs28408445 0.04324
NM_006846.4(SPINK5):c.1431-75C>G rs10477362 0.04317
NM_006846.4(SPINK5):c.1692+200G>T rs73794664 0.04316
NM_006846.4(SPINK5):c.1093-226A>G rs73271118 0.04295
NM_006846.4(SPINK5):c.2965-10G>C rs58888156 0.04288
NM_006846.4(SPINK5):c.2015+307C>T rs6878956 0.04248
NM_006846.4(SPINK5):c.1011-212G>A rs73794662 0.04050
NM_006846.4(SPINK5):c.1888-53T>C rs3815734 0.03726
NM_006846.4(SPINK5):c.410+124A>G rs73269189 0.03445
NM_006846.4(SPINK5):c.1851T>C (p.Ala617=) rs17718737 0.03431
NM_006846.4(SPINK5):c.*59C>T rs73794699 0.03338
NM_006846.4(SPINK5):c.1479+257T>C rs77692289 0.03205
NM_006846.4(SPINK5):c.316G>A (p.Asp106Asn) rs17860502 0.03121
NC_000005.10:g.148063797G>A rs2287774 0.03115
NM_006846.4(SPINK5):c.2740-395C>T rs17637711 0.03100
NM_006846.4(SPINK5):c.1302+86A>C rs2303069 0.03095
NM_006846.4(SPINK5):c.531G>A (p.Arg177=) rs35121983 0.02736
NM_006846.4(SPINK5):c.2915A>G (p.His972Arg) rs17705005 0.02442
NM_006846.4(SPINK5):c.2314-321C>A rs111312718 0.02101
NM_006846.4(SPINK5):c.282+198_282+199del rs10606874 0.02066
NM_006846.4(SPINK5):c.1092+160T>A rs79966756 0.01844
NM_006846.4(SPINK5):c.1479+39T>G rs116515232 0.01769
NM_006846.4(SPINK5):c.2113-18G>A rs73271150 0.01592
NM_006846.4(SPINK5):c.1303-100G>A rs73271122 0.01577
NM_006846.4(SPINK5):c.2112+247T>C rs56683639 0.01572
NM_006846.4(SPINK5):c.2867+273T>A rs73271167 0.01570
NM_006846.4(SPINK5):c.2762A>G (p.Asn921Ser) rs73271166 0.01566
NM_006846.4(SPINK5):c.119G>C (p.Gly40Ala) rs73269156 0.01335
NM_006846.4(SPINK5):c.2754A>G (p.Glu918=) rs114635730 0.01171
NM_006846.4(SPINK5):c.2864T>C (p.Val955Ala) rs115820034 0.01140
NM_006846.4(SPINK5):c.1552C>T (p.Arg518Cys) rs115504632 0.01067
NM_006846.4(SPINK5):c.3186+8C>T rs115366845 0.01052
NM_006846.4(SPINK5):c.1764T>G (p.Ile588Met) rs35877540 0.01015
NM_006846.4(SPINK5):c.2905A>G (p.Lys969Glu) rs3188691 0.00856
NM_006846.4(SPINK5):c.2241-6C>T rs190365795 0.00842
NM_006846.4(SPINK5):c.2895G>A (p.Lys965=) rs34966234 0.00755
NM_006846.4(SPINK5):c.-19G>A rs12522603 0.00660
NM_006846.4(SPINK5):c.1322G>A (p.Arg441His) rs34393923 0.00653
NM_006846.4(SPINK5):c.802C>T (p.Arg268Cys) rs142558269 0.00581
NM_006846.4(SPINK5):c.2667-4G>A rs180955184 0.00542
NM_006846.4(SPINK5):c.1011-141dup rs11405253
NM_006846.4(SPINK5):c.1092+183_1092+184del rs66488719
NM_006846.4(SPINK5):c.1092+199_1092+204del rs3214448
NM_006846.4(SPINK5):c.1092+202_1092+204del rs3214448
NM_006846.4(SPINK5):c.1092+203_1092+204del rs3214448
NM_006846.4(SPINK5):c.1092+204del rs3214448
NM_006846.4(SPINK5):c.1093-10A>G rs2303062
NM_006846.4(SPINK5):c.1431-39del rs34473560
NM_006846.4(SPINK5):c.1557C>A (p.Gly519=) rs880687
NM_006846.4(SPINK5):c.1607+47C>T rs41291431
NM_006846.4(SPINK5):c.1607+93_1607+94del rs3036740
NM_006846.4(SPINK5):c.1820+154T>C rs2287765
NM_006846.4(SPINK5):c.1821-182AAAC[4] rs149567477
NM_006846.4(SPINK5):c.1821-188_1821-187insAACCAA rs113307434
NM_006846.4(SPINK5):c.1821-47T>G rs72660259
NM_006846.4(SPINK5):c.1888-114dup rs35860121
NM_006846.4(SPINK5):c.1888-80dup rs56820817
NM_006846.4(SPINK5):c.1888-93_1888-92insTTT rs377089918
NM_006846.4(SPINK5):c.1888-93dup rs377089918
NM_006846.4(SPINK5):c.2088TGG[2] (p.Gly701del) rs111662216
NM_006846.4(SPINK5):c.209+325del rs139566903
NM_006846.4(SPINK5):c.2113-129T>C rs6891892
NM_006846.4(SPINK5):c.2313+31C>G rs9325073
NM_006846.4(SPINK5):c.2539-269AT[8] rs145110538
NM_006846.4(SPINK5):c.2539-314_2539-287del rs201903088
NM_006846.4(SPINK5):c.2539-314_2539-309del rs1439906364
NM_006846.4(SPINK5):c.2539-314_2539-311del rs1196649523
NM_006846.4(SPINK5):c.2667-12del rs368593462
NM_006846.4(SPINK5):c.2667-13delinsTT rs1554106953
NM_006846.4(SPINK5):c.2667-14dup rs3036731
NM_006846.4(SPINK5):c.2667-15_2667-14dup rs3036731
NM_006846.4(SPINK5):c.2739+141A>T rs2303074
NM_006846.4(SPINK5):c.2868-149C>T rs41291435
NM_006846.4(SPINK5):c.3187-76C>G rs4334874
NM_006846.4(SPINK5):c.474+240_474+241dup rs397777404
NM_006846.4(SPINK5):c.474+241dup rs397777404
NM_006846.4(SPINK5):c.475-86G>C rs4529181
NM_006846.4(SPINK5):c.603-136G>C rs72660254
NM_006846.4(SPINK5):c.667-250G>A rs7700488
NM_006846.4(SPINK5):c.81+174CA[10] rs3036741
NM_006846.4(SPINK5):c.81+174CA[9] rs3036741
NM_006846.4(SPINK5):c.81+183_81+184insAA rs200149071
NM_006846.4(SPINK5):c.882+119_882+121del rs147242208
NM_006846.4(SPINK5):c.883-76_883-75insAATT rs140098537
NM_006846.4(SPINK5):c.883-76_883-75insAATTT rs55959555

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.