List of variants in gene WDR45 reported as uncertain significance by GeneDx

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 18

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HGVS	dbSNP	gnomAD frequency
NM_001029896.2(WDR45):c.325C>T (p.Arg109Cys)	rs369310756	0.00008
NM_001029896.2(WDR45):c.524C>T (p.Ala175Val)	rs192312429	0.00002
NM_001029896.2(WDR45):c.332G>A (p.Arg111His)	rs782395953	0.00001
NM_001029896.2(WDR45):c.421C>G (p.Arg141Gly)	rs373717091	0.00001
NM_001029896.2(WDR45):c.448C>G (p.Leu150Val)	rs782794836	0.00001
NM_001029896.2(WDR45):c.947C>G (p.Thr316Ser)	rs781794138	0.00001
NM_001029896.2(WDR45):c.313G>A (p.Val105Met)
NM_001029896.2(WDR45):c.322G>A (p.Val108Met)
NM_001029896.2(WDR45):c.439C>T (p.Leu147Phe)
NM_001029896.2(WDR45):c.459C>A (p.Ser153Arg)	rs2147815709
NM_001029896.2(WDR45):c.490C>T (p.His164Tyr)
NM_001029896.2(WDR45):c.560C>T (p.Thr187Met)	rs1294236595
NM_001029896.2(WDR45):c.665C>A (p.Thr222Lys)
NM_001029896.2(WDR45):c.669A>C (p.Gln223His)	rs2147815349
NM_001029896.2(WDR45):c.818G>A (p.Arg273His)
NM_001029896.2(WDR45):c.871G>A (p.Val291Met)	rs1557083897
NM_001029896.2(WDR45):c.940C>T (p.Arg314Cys)	rs1307990056
NM_001029896.2(WDR45):c.956A>T (p.Asn319Ile)	rs2147814777

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