List of variants in gene BRCA1 reported as benign by Michigan Medical Genetics Laboratories, University of Michigan

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 43

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HGVS	dbSNP	gnomAD frequency
NM_007294.4(BRCA1):c.2082C>T (p.Ser694=)	rs1799949	0.30810
NM_007294.4(BRCA1):c.4308T>C (p.Ser1436=)	rs1060915	0.29170
NM_007294.4(BRCA1):c.3113A>G (p.Glu1038Gly)	rs16941	0.29115
NM_007294.4(BRCA1):c.2311T>C (p.Leu771=)	rs16940	0.29035
NM_007294.4(BRCA1):c.442-34C>T	rs799923	0.15730
NM_007294.4(BRCA1):c.2077G>A (p.Asp693Asn)	rs4986850	0.05782
NM_007294.4(BRCA1):c.1067A>G (p.Gln356Arg)	rs1799950	0.04695
NM_007294.4(BRCA1):c.*36C>G	rs3092995	0.01385
NM_007294.4(BRCA1):c.4956G>A (p.Met1652Ile)	rs1799967	0.01348
NM_007294.4(BRCA1):c.3119G>A (p.Ser1040Asn)	rs4986852	0.01109
NM_007294.4(BRCA1):c.212+23T>A	rs8176128	0.01018
NM_007294.4(BRCA1):c.2458A>G (p.Lys820Glu)	rs56082113	0.00964
NM_007294.4(BRCA1):c.1971A>G (p.Gln657=)	rs28897679	0.00707
NM_007294.4(BRCA1):c.5468-10C>A	rs8176316	0.00464
NM_007294.4(BRCA1):c.4535G>T (p.Ser1512Ile)	rs1800744	0.00240
NM_007294.4(BRCA1):c.2814A>G (p.Pro938=)	rs80356851	0.00183
NM_007294.4(BRCA1):c.1137T>G (p.Ile379Met)	rs56128296	0.00158
NM_007294.4(BRCA1):c.2109A>G (p.Thr703=)	rs4986844	0.00147
NM_007294.4(BRCA1):c.4600G>A (p.Val1534Met)	rs55815649	0.00145
NM_007294.4(BRCA1):c.2521C>T (p.Arg841Trp)	rs1800709	0.00137
NM_007294.4(BRCA1):c.591C>T (p.Cys197=)	rs1799965	0.00117
NM_007294.4(BRCA1):c.765G>A (p.Glu255=)	rs62625299	0.00107
NM_007294.4(BRCA1):c.4883T>C (p.Met1628Thr)	rs4986854	0.00098
NM_007294.4(BRCA1):c.301+8T>C	rs80358101	0.00054
NM_007294.4(BRCA1):c.2566T>C (p.Tyr856His)	rs80356892	0.00046
NM_007294.4(BRCA1):c.1456T>C (p.Phe486Leu)	rs55906931	0.00034
NM_007294.4(BRCA1):c.1648A>C (p.Asn550His)	rs56012641	0.00029
NM_007294.4(BRCA1):c.536A>G (p.Tyr179Cys)	rs56187033	0.00029
NM_007294.4(BRCA1):c.736T>G (p.Leu246Val)	rs28897675	0.00026
NM_007294.4(BRCA1):c.1911T>C (p.Thr637=)	rs62625305	0.00013
NM_007294.4(BRCA1):c.2315T>C (p.Val772Ala)	rs80357467	0.00012
NM_007294.4(BRCA1):c.693G>A (p.Thr231=)	rs62625298	0.00011
NM_007294.4(BRCA1):c.4097-28A>G	rs869320777	0.00010
NM_007294.4(BRCA1):c.314A>G (p.Tyr105Cys)	rs28897673	0.00009
NM_007294.4(BRCA1):c.4653T>C (p.Ser1551=)	rs587780863	0.00005
NM_007294.4(BRCA1):c.5074+6C>G	rs80358032	0.00002
NM_007294.4(BRCA1):c.4910C>T (p.Pro1637Leu)	rs80357048	0.00001
NM_007294.4(BRCA1):c.1843TCT[1] (p.Ser616del)	rs80358329
NM_007294.4(BRCA1):c.2612C>T (p.Pro871Leu)	rs799917
NM_007294.4(BRCA1):c.441+18CTT[6]	rs147856441
NM_007294.4(BRCA1):c.441+36_441+49del	rs373413425
NM_007294.4(BRCA1):c.4837A>G (p.Ser1613Gly)	rs1799966
NM_007294.4(BRCA1):c.81-14C>T	rs80358006

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