List of variants in gene BRCA1 reported as benign by Counsyl

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 46

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HGVS	dbSNP	gnomAD frequency
NM_007294.4(BRCA1):c.2082C>T (p.Ser694=)	rs1799949	0.30810
NM_007294.4(BRCA1):c.*1287C>T	rs12516	0.30331
NM_007294.4(BRCA1):c.5152+66G>A	rs3092994	0.30314
NM_007294.4(BRCA1):c.4308T>C (p.Ser1436=)	rs1060915	0.29170
NM_007294.4(BRCA1):c.3113A>G (p.Glu1038Gly)	rs16941	0.29115
NM_007294.4(BRCA1):c.2311T>C (p.Leu771=)	rs16940	0.29035
NM_007294.4(BRCA1):c.2077G>A (p.Asp693Asn)	rs4986850	0.05782
NM_007294.4(BRCA1):c.1067A>G (p.Gln356Arg)	rs1799950	0.04695
NM_007294.4(BRCA1):c.*36C>G	rs3092995	0.01385
NM_007294.4(BRCA1):c.4956G>A (p.Met1652Ile)	rs1799967	0.01348
NM_007294.4(BRCA1):c.3119G>A (p.Ser1040Asn)	rs4986852	0.01109
NM_007294.4(BRCA1):c.2458A>G (p.Lys820Glu)	rs56082113	0.00964
NM_007294.4(BRCA1):c.*781C>T	rs8176319	0.00732
NM_007294.4(BRCA1):c.1971A>G (p.Gln657=)	rs28897679	0.00707
NM_007294.4(BRCA1):c.5406+8T>C	rs55946644	0.00514
NM_007294.4(BRCA1):c.5468-10C>A	rs8176316	0.00464
NM_007294.4(BRCA1):c.557C>A (p.Ser186Tyr)	rs55688530	0.00301
NM_007294.4(BRCA1):c.4987-20A>G	rs80358035	0.00252
NM_007294.4(BRCA1):c.4535G>T (p.Ser1512Ile)	rs1800744	0.00240
NM_007294.4(BRCA1):c.114G>A (p.Lys38=)	rs1800062	0.00233
NM_007294.4(BRCA1):c.2167A>G (p.Asn723Asp)	rs4986845	0.00209
NM_007294.4(BRCA1):c.4682C>T (p.Thr1561Ile)	rs56158747	0.00150
NM_007294.4(BRCA1):c.4600G>A (p.Val1534Met)	rs55815649	0.00145
NM_007294.4(BRCA1):c.3024G>A (p.Met1008Ile)	rs1800704	0.00065
NM_007294.4(BRCA1):c.2566T>C (p.Tyr856His)	rs80356892	0.00046
NM_007294.4(BRCA1):c.548-17G>T	rs80358014	0.00028
NM_007294.4(BRCA1):c.2773A>C (p.Ile925Leu)	rs4986847	0.00013
NM_007294.4(BRCA1):c.301+7G>A	rs80358113	0.00006
NM_007294.4(BRCA1):c.4636G>A (p.Asp1546Asn)	rs28897691	0.00006
NM_007294.4(BRCA1):c.2669G>T (p.Gly890Val)	rs80356874	0.00004
NM_007294.4(BRCA1):c.427G>A (p.Glu143Lys)	rs80356991	0.00004
NM_007294.4(BRCA1):c.4402A>C (p.Asn1468His)	rs80357022	0.00004
NM_007294.4(BRCA1):c.5252G>A (p.Arg1751Gln)	rs80357442	0.00004
NM_007294.4(BRCA1):c.4185+10G>C	rs80358104	0.00003
NM_007294.4(BRCA1):c.2525A>G (p.Glu842Gly)	rs28897684	0.00002
NM_007294.4(BRCA1):c.5576C>G (p.Pro1859Arg)	rs80357322	0.00002
NM_007294.4(BRCA1):c.1105G>A (p.Asp369Asn)	rs56056711	0.00001
NM_007294.4(BRCA1):c.133A>C (p.Lys45Gln)	rs769650474	0.00001
NM_007294.4(BRCA1):c.4985T>C (p.Phe1662Ser)	rs28897695	0.00001
NM_007294.4(BRCA1):c.1418A>G (p.Asn473Ser)	rs80357057
NM_007294.4(BRCA1):c.2612C>T (p.Pro871Leu)	rs799917
NM_007294.4(BRCA1):c.4327C>G (p.Arg1443Gly)	rs41293455
NM_007294.4(BRCA1):c.4636G>T (p.Asp1546Tyr)	rs28897691
NM_007294.4(BRCA1):c.4837A>G (p.Ser1613Gly)	rs1799966
NM_007294.4(BRCA1):c.5572A>C (p.Ile1858Leu)	rs765656957
NM_007294.4(BRCA1):c.81-14C>T	rs80358006

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