List of variants in gene BRCA1 reported as benign by Women's Health and Genetics/Laboratory Corporation of America, LabCorp

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 102

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HGVS	dbSNP	gnomAD frequency
NM_007294.4(BRCA1):c.2082C>T (p.Ser694=)	rs1799949	0.30810
NM_007294.4(BRCA1):c.4308T>C (p.Ser1436=)	rs1060915	0.29170
NM_007294.4(BRCA1):c.3113A>G (p.Glu1038Gly)	rs16941	0.29115
NM_007294.4(BRCA1):c.2311T>C (p.Leu771=)	rs16940	0.29035
NM_007294.4(BRCA1):c.2077G>A (p.Asp693Asn)	rs4986850	0.05782
NM_007294.4(BRCA1):c.1067A>G (p.Gln356Arg)	rs1799950	0.04695
NM_007294.4(BRCA1):c.4956G>A (p.Met1652Ile)	rs1799967	0.01348
NM_007294.4(BRCA1):c.3119G>A (p.Ser1040Asn)	rs4986852	0.01109
NM_007294.4(BRCA1):c.2458A>G (p.Lys820Glu)	rs56082113	0.00964
NM_007294.4(BRCA1):c.1971A>G (p.Gln657=)	rs28897679	0.00707
NM_007294.4(BRCA1):c.5406+8T>C	rs55946644	0.00514
NM_007294.4(BRCA1):c.5468-10C>A	rs8176316	0.00464
NM_007294.4(BRCA1):c.4987-20A>G	rs80358035	0.00252
NM_007294.4(BRCA1):c.4535G>T (p.Ser1512Ile)	rs1800744	0.00240
NM_007294.4(BRCA1):c.114G>A (p.Lys38=)	rs1800062	0.00233
NM_007294.4(BRCA1):c.2167A>G (p.Asn723Asp)	rs4986845	0.00209
NM_007294.4(BRCA1):c.1137T>G (p.Ile379Met)	rs56128296	0.00158
NM_007294.4(BRCA1):c.4600G>A (p.Val1534Met)	rs55815649	0.00145
NM_007294.4(BRCA1):c.2521C>T (p.Arg841Trp)	rs1800709	0.00137
NM_007294.4(BRCA1):c.3083G>A (p.Arg1028His)	rs80357459	0.00106
NM_007294.4(BRCA1):c.1427A>G (p.His476Arg)	rs55720177	0.00066
NM_007294.4(BRCA1):c.81-12C>G	rs80358055	0.00066
NM_007294.4(BRCA1):c.4992C>T (p.Leu1664=)	rs142459158	0.00061
NM_007294.4(BRCA1):c.1487G>A (p.Arg496His)	rs28897677	0.00060
NM_007294.4(BRCA1):c.4691T>C (p.Leu1564Pro)	rs56119278	0.00059
NM_007294.4(BRCA1):c.5348T>C (p.Met1783Thr)	rs55808233	0.00058
NM_007294.4(BRCA1):c.1456T>C (p.Phe486Leu)	rs55906931	0.00034
NM_007294.4(BRCA1):c.1036C>T (p.Pro346Ser)	rs80357015	0.00032
NM_007294.4(BRCA1):c.1648A>C (p.Asn550His)	rs56012641	0.00029
NM_007294.4(BRCA1):c.2368A>G (p.Thr790Ala)	rs41286298	0.00029
NM_007294.4(BRCA1):c.548-17G>T	rs80358014	0.00028
NM_007294.4(BRCA1):c.4358-10C>T	rs80358111	0.00024
NM_007294.4(BRCA1):c.571G>A (p.Val191Ile)	rs80357090	0.00021
NM_007294.4(BRCA1):c.1789G>A (p.Glu597Lys)	rs55650082	0.00019
NM_007294.4(BRCA1):c.5005G>T (p.Ala1669Ser)	rs80357087	0.00019
NM_007294.4(BRCA1):c.4132G>A (p.Val1378Ile)	rs28897690	0.00017
NM_007294.4(BRCA1):c.2773A>C (p.Ile925Leu)	rs4986847	0.00013
NM_007294.4(BRCA1):c.5304C>T (p.Cys1768=)	rs138493864	0.00012
NM_007294.4(BRCA1):c.1065G>A (p.Lys355=)	rs41286292	0.00011
NM_007294.4(BRCA1):c.441+18C>T	rs371973519	0.00011
NM_007294.4(BRCA1):c.5152+20T>A	rs376836050	0.00009
NM_007294.4(BRCA1):c.4882A>G (p.Met1628Val)	rs80357465	0.00008
NM_007294.4(BRCA1):c.1865C>T (p.Ala622Val)	rs56039126	0.00007
NM_007294.4(BRCA1):c.5332+13G>T	rs372391060	0.00007
NM_007294.4(BRCA1):c.1392C>T (p.Thr464=)	rs533802049	0.00006
NM_007294.4(BRCA1):c.1534C>T (p.Leu512Phe)	rs41286294	0.00006
NM_007294.4(BRCA1):c.2412G>C (p.Gln804His)	rs55746541	0.00006
NM_007294.4(BRCA1):c.2522G>A (p.Arg841Gln)	rs80357337	0.00006
NM_007294.4(BRCA1):c.301+7G>A	rs80358113	0.00006
NM_007294.4(BRCA1):c.5278-14C>G	rs80358105	0.00006
NM_007294.4(BRCA1):c.199G>T (p.Asp67Tyr)	rs80357102	0.00005
NM_007294.4(BRCA1):c.5117G>C (p.Gly1706Ala)	rs80356860	0.00005
NM_007294.4(BRCA1):c.1511G>A (p.Arg504His)	rs56272539	0.00004
NM_007294.4(BRCA1):c.1616C>T (p.Thr539Met)	rs80357374	0.00004
NM_007294.4(BRCA1):c.2286A>T (p.Arg762Ser)	rs273898682	0.00004
NM_007294.4(BRCA1):c.2351C>T (p.Ser784Leu)	rs55914168	0.00004
NM_007294.4(BRCA1):c.4357+17A>G	rs80358180	0.00004
NM_007294.4(BRCA1):c.4402A>C (p.Asn1468His)	rs80357022	0.00004
NM_007294.4(BRCA1):c.4729T>C (p.Ser1577Pro)	rs80356909	0.00004
NM_007294.4(BRCA1):c.5252G>A (p.Arg1751Gln)	rs80357442	0.00004
NM_007294.4(BRCA1):c.81-11del	rs273902788	0.00004
NM_007294.4(BRCA1):c.396C>A (p.Asn132Lys)	rs80357413	0.00003
NM_007294.4(BRCA1):c.671-8A>G	rs80358144	0.00003
NM_007294.4(BRCA1):c.81-6T>C	rs80358179	0.00003
NM_007294.4(BRCA1):c.811G>A (p.Val271Met)	rs80357244	0.00003
NM_007294.4(BRCA1):c.1001C>T (p.Pro334Leu)	rs41286290	0.00002
NM_007294.4(BRCA1):c.2525A>G (p.Glu842Gly)	rs28897684	0.00002
NM_007294.4(BRCA1):c.2662C>T (p.His888Tyr)	rs80357480	0.00002
NM_007294.4(BRCA1):c.4955T>C (p.Met1652Thr)	rs80356968	0.00002
NM_007294.4(BRCA1):c.5074+6C>G	rs80358032	0.00002
NM_007294.4(BRCA1):c.5402G>A (p.Gly1801Asp)	rs531210457	0.00002
NM_007294.4(BRCA1):c.5576C>G (p.Pro1859Arg)	rs80357322	0.00002
NM_007294.4(BRCA1):c.824G>A (p.Gly275Asp)	rs397509327	0.00002
NM_007294.4(BRCA1):c.1105G>A (p.Asp369Asn)	rs56056711	0.00001
NM_007294.4(BRCA1):c.154C>T (p.Leu52Phe)	rs80357084	0.00001
NM_007294.4(BRCA1):c.2584A>G (p.Lys862Glu)	rs80356927	0.00001
NM_007294.4(BRCA1):c.4097-10G>A	rs80358057	0.00001
NM_007294.4(BRCA1):c.4204C>T (p.His1402Tyr)	rs80357365	0.00001
NM_007294.4(BRCA1):c.4347A>G (p.Thr1449=)	rs80356840	0.00001
NM_007294.4(BRCA1):c.4485-10A>G	rs863224420	0.00001
NM_007294.4(BRCA1):c.4910C>T (p.Pro1637Leu)	rs80357048	0.00001
NM_007294.4(BRCA1):c.4985T>C (p.Phe1662Ser)	rs28897695	0.00001
NM_007294.4(BRCA1):c.5075-9A>T	rs80358059	0.00001
NM_007294.4(BRCA1):c.5153-13A>G	rs45471406	0.00001
NM_007294.4(BRCA1):c.5333A>G (p.Asp1778Gly)	rs80357041	0.00001
NM_007294.4(BRCA1):c.5412C>T (p.Val1804=)	rs730881456	0.00001
NM_007294.4(BRCA1):c.81-17C>G	rs757442952	0.00001
NM_007294.4(BRCA1):c.1106_1108del (p.Asp369del)	rs80358325
NM_007294.4(BRCA1):c.135-23CTTT[2]	rs878854931
NM_007294.4(BRCA1):c.2232T>C (p.Ala744=)	rs4986846
NM_007294.4(BRCA1):c.2612C>T (p.Pro871Leu)	rs799917
NM_007294.4(BRCA1):c.305C>G (p.Ala102Gly)	rs80357190
NM_007294.4(BRCA1):c.4186-10G>A	rs80358172
NM_007294.4(BRCA1):c.4327C>G (p.Arg1443Gly)	rs41293455
NM_007294.4(BRCA1):c.441+17T>C	rs368415464
NM_007294.4(BRCA1):c.4837A>G (p.Ser1613Gly)	rs1799966
NM_007294.4(BRCA1):c.5198A>G (p.Asp1733Gly)	rs80357270
NM_007294.4(BRCA1):c.547+14del	rs273902771
NM_007294.4(BRCA1):c.5572A>C (p.Ile1858Leu)	rs765656957
NM_007294.4(BRCA1):c.671-12del	rs273902781
NM_007294.4(BRCA1):c.81-13C>A	rs56328013
NM_007294.4(BRCA1):c.823G>A (p.Gly275Ser)	rs8176153

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