List of variants in gene FANCC reported as uncertain significance by Invitae

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 136

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HGVS	dbSNP	gnomAD frequency
NM_000136.3(FANCC):c.29G>A (p.Cys10Tyr)	rs143152201	0.00019
NM_000136.3(FANCC):c.248A>G (p.Tyr83Cys)	rs140992397	0.00007
NM_000136.3(FANCC):c.345+6A>T	rs368595927	0.00007
NM_000136.3(FANCC):c.395C>G (p.Ala132Gly)	rs587779905	0.00005
NM_000136.3(FANCC):c.202G>C (p.Gly68Arg)	rs777111154	0.00004
NM_000136.3(FANCC):c.28T>G (p.Cys10Gly)	rs147479204	0.00004
NM_000136.3(FANCC):c.491A>C (p.Asn164Thr)	rs950623649	0.00004
NM_000136.3(FANCC):c.9A>T (p.Gln3His)	rs769585639	0.00004
NM_000136.3(FANCC):c.127G>A (p.Glu43Lys)	rs374836770	0.00003
NM_000136.3(FANCC):c.146A>G (p.Tyr49Cys)	rs761845692	0.00003
NM_000136.3(FANCC):c.191T>G (p.Phe64Cys)	rs375921240	0.00003
NM_000136.3(FANCC):c.338G>C (p.Trp113Ser)	rs1064793405	0.00003
NM_000136.3(FANCC):c.46A>T (p.Met16Leu)	rs1390412870	0.00003
NM_000136.3(FANCC):c.521G>A (p.Arg174Gln)	rs755283850	0.00003
NM_000136.3(FANCC):c.233C>A (p.Pro78His)	rs138722298	0.00002
NM_000136.3(FANCC):c.349G>A (p.Val117Ile)	rs781167993	0.00002
NM_000136.3(FANCC):c.383A>G (p.Asp128Gly)	rs555753798	0.00002
NM_000136.3(FANCC):c.473C>T (p.Ala158Val)	rs776429990	0.00002
NM_000136.3(FANCC):c.-2A>G	rs773045474	0.00001
NM_000136.3(FANCC):c.-79+1G>A	rs1228886763	0.00001
NM_000136.3(FANCC):c.104G>C (p.Cys35Ser)	rs143212932	0.00001
NM_000136.3(FANCC):c.109C>G (p.His37Asp)	rs864622230	0.00001
NM_000136.3(FANCC):c.112G>A (p.Val38Met)	rs778951584	0.00001
NM_000136.3(FANCC):c.143T>C (p.Met48Thr)	rs1353498563	0.00001
NM_000136.3(FANCC):c.160G>A (p.Glu54Lys)	rs1564794487	0.00001
NM_000136.3(FANCC):c.166-4_166-1dup	rs746016938	0.00001
NM_000136.3(FANCC):c.176C>T (p.Thr59Ile)	rs149566909	0.00001
NM_000136.3(FANCC):c.209T>A (p.Leu70Gln)	rs150174412	0.00001
NM_000136.3(FANCC):c.239T>C (p.Ile80Thr)	rs4647419	0.00001
NM_000136.3(FANCC):c.262A>C (p.Lys88Gln)	rs1060502519	0.00001
NM_000136.3(FANCC):c.271A>G (p.Ile91Val)	rs771619614	0.00001
NM_000136.3(FANCC):c.278G>A (p.Cys93Tyr)	rs774029807	0.00001
NM_000136.3(FANCC):c.290T>C (p.Leu97Pro)	rs1223097554	0.00001
NM_000136.3(FANCC):c.329T>C (p.Leu110Pro)	rs777731560	0.00001
NM_000136.3(FANCC):c.345G>A (p.Gln115=)	rs1031713372	0.00001
NM_000136.3(FANCC):c.347G>A (p.Gly116Asp)	rs1282106098	0.00001
NM_000136.3(FANCC):c.397C>T (p.Leu133Phe)	rs587779906	0.00001
NM_000136.3(FANCC):c.407A>C (p.Gln136Pro)	rs1180924540	0.00001
NM_000136.3(FANCC):c.436_438del (p.Tyr146del)	rs761347179	0.00001
NM_000136.3(FANCC):c.440C>T (p.Pro147Leu)	rs730881711	0.00001
NM_000136.3(FANCC):c.46A>G (p.Met16Val)	rs1390412870	0.00001
NM_000136.3(FANCC):c.472G>C (p.Ala158Pro)	rs372338418	0.00001
NM_000136.3(FANCC):c.521+5G>C	rs1301899973	0.00001
NM_000136.3(FANCC):c.76T>A (p.Ser26Thr)	rs1165230596	0.00001
NM_000136.3(FANCC):c.8A>C (p.Gln3Pro)	rs1415268424	0.00001
NC_000009.11:g.(?_97863989)_(98079991_?)dup
NC_000009.11:g.(?_98002921)_(98079991_?)dup
NM_000136.3(FANCC):c.-19C>T
NM_000136.3(FANCC):c.-59T>C
NM_000136.3(FANCC):c.-73A>G	rs1831191027
NM_000136.3(FANCC):c.-73A>T	rs1831191027
NM_000136.3(FANCC):c.-78-1G>C	rs2136103070
NM_000136.3(FANCC):c.-78-2A>G	rs587779898
NM_000136.3(FANCC):c.-78-3C>A
NM_000136.3(FANCC):c.-79+1del
NM_000136.3(FANCC):c.-79+2dup	rs2136457021
NM_000136.3(FANCC):c.-8T>C
NM_000136.3(FANCC):c.104G>A (p.Cys35Tyr)	rs143212932
NM_000136.3(FANCC):c.110A>C (p.His37Pro)	rs1564794663
NM_000136.3(FANCC):c.112G>C (p.Val38Leu)	rs778951584
NM_000136.3(FANCC):c.120G>C (p.Gln40His)	rs905858585
NM_000136.3(FANCC):c.131T>C (p.Phe44Ser)	rs1588353402
NM_000136.3(FANCC):c.134T>G (p.Leu45Arg)	rs2136100589
NM_000136.3(FANCC):c.140A>C (p.Lys47Thr)	rs1588353368
NM_000136.3(FANCC):c.141G>T (p.Lys47Asn)
NM_000136.3(FANCC):c.14C>T (p.Ser5Leu)	rs1831182314
NM_000136.3(FANCC):c.156G>C (p.Leu52Phe)	rs1060502518
NM_000136.3(FANCC):c.164T>C (p.Met55Thr)	rs1060502513
NM_000136.3(FANCC):c.165+5G>T
NM_000136.3(FANCC):c.166-3C>T	rs1554857868
NM_000136.3(FANCC):c.166G>T (p.Asp56Tyr)
NM_000136.3(FANCC):c.167A>T (p.Asp56Val)	rs759662786
NM_000136.3(FANCC):c.169T>G (p.Ser57Ala)
NM_000136.3(FANCC):c.173A>G (p.Asn58Ser)	rs1831061339
NM_000136.3(FANCC):c.188G>C (p.Arg63Thr)	rs1588350373
NM_000136.3(FANCC):c.189A>T (p.Arg63Ser)	rs773388565
NM_000136.3(FANCC):c.197C>T (p.Thr66Ile)	rs762234072
NM_000136.3(FANCC):c.213G>T (p.Leu71Phe)	rs2136091002
NM_000136.3(FANCC):c.214G>T (p.Ala72Ser)	rs567465885
NM_000136.3(FANCC):c.21T>A (p.Asp7Glu)
NM_000136.3(FANCC):c.228G>T (p.Trp76Cys)	rs876661132
NM_000136.3(FANCC):c.232C>G (p.Pro78Ala)	rs2136090802
NM_000136.3(FANCC):c.23T>C (p.Leu8Pro)	rs752249253
NM_000136.3(FANCC):c.246A>G (p.Ala82=)	rs1554857810
NM_000136.3(FANCC):c.254A>G (p.Glu85Gly)
NM_000136.3(FANCC):c.266T>G (p.Ile89Ser)	rs2136049598
NM_000136.3(FANCC):c.268C>A (p.Leu90Ile)	rs2136049561
NM_000136.3(FANCC):c.273A>G (p.Ile91Met)
NM_000136.3(FANCC):c.287G>T (p.Cys96Phe)
NM_000136.3(FANCC):c.292A>G (p.Ile98Val)
NM_000136.3(FANCC):c.293T>C (p.Ile98Thr)	rs1830583670
NM_000136.3(FANCC):c.328C>G (p.Leu110Val)	rs1554856102
NM_000136.3(FANCC):c.328C>T (p.Leu110Phe)
NM_000136.3(FANCC):c.340A>G (p.Ile114Val)	rs1830580247
NM_000136.3(FANCC):c.340A>T (p.Ile114Leu)	rs1830580247
NM_000136.3(FANCC):c.345+3A>G
NM_000136.3(FANCC):c.346G>C (p.Gly116Arg)	rs1440493340
NM_000136.3(FANCC):c.349_360del (p.Val117_His120del)	rs1825723799
NM_000136.3(FANCC):c.34T>G (p.Tyr12Asp)	rs766173332
NM_000136.3(FANCC):c.34_36del (p.Tyr12del)	rs1554858333
NM_000136.3(FANCC):c.355T>C (p.Ser119Pro)
NM_000136.3(FANCC):c.35A>G (p.Tyr12Cys)	rs762884109
NM_000136.3(FANCC):c.371C>T (p.Ala124Val)	rs374602991
NM_000136.3(FANCC):c.374T>C (p.Leu125Pro)	rs2135588560
NM_000136.3(FANCC):c.390A>T (p.Glu130Asp)	rs1419677503
NM_000136.3(FANCC):c.391G>A (p.Val131Ile)	rs543546719
NM_000136.3(FANCC):c.3G>A (p.Met1Ile)	rs1368374192
NM_000136.3(FANCC):c.406C>G (p.Gln136Glu)
NM_000136.3(FANCC):c.413T>G (p.Leu138Arg)	rs1564720454
NM_000136.3(FANCC):c.422C>T (p.Ala141Val)	rs2135587894
NM_000136.3(FANCC):c.424C>G (p.Pro142Ala)	rs864622581
NM_000136.3(FANCC):c.425C>A (p.Pro142His)	rs1064793605
NM_000136.3(FANCC):c.430G>T (p.Asp144Tyr)	rs2135587786
NM_000136.3(FANCC):c.432T>G (p.Asp144Glu)	rs1825715851
NM_000136.3(FANCC):c.433T>C (p.Tyr145His)	rs751054264
NM_000136.3(FANCC):c.437A>C (p.Tyr146Ser)	rs1564720359
NM_000136.3(FANCC):c.439C>G (p.Pro147Ala)
NM_000136.3(FANCC):c.456+6T>C
NM_000136.3(FANCC):c.457-10del	rs763416214
NM_000136.3(FANCC):c.457-16T>A
NM_000136.3(FANCC):c.460G>C (p.Val154Leu)
NM_000136.3(FANCC):c.469T>A (p.Leu157Ile)	rs1825652301
NM_000136.3(FANCC):c.470T>C (p.Leu157Ser)	rs200828924
NM_000136.3(FANCC):c.485G>C (p.Arg162Thr)	rs1825650685
NM_000136.3(FANCC):c.491A>T (p.Asn164Ile)	rs950623649
NM_000136.3(FANCC):c.494A>G (p.His165Arg)
NM_000136.3(FANCC):c.509A>G (p.Asn170Ser)	rs749322338
NM_000136.3(FANCC):c.511A>C (p.Thr171Pro)
NM_000136.3(FANCC):c.511A>G (p.Thr171Ala)	rs1554842592
NM_000136.3(FANCC):c.514C>G (p.Gln172Glu)	rs769998628
NM_000136.3(FANCC):c.521+5G>A	rs1301899973
NM_000136.3(FANCC):c.521+5del	rs2135578132
NM_000136.3(FANCC):c.53A>C (p.Lys18Thr)	rs2136101612
NM_000136.3(FANCC):c.61G>C (p.Val21Leu)	rs772386467
NM_000136.3(FANCC):c.80C>G (p.Thr27Ser)	rs1489419613
NM_000136.3(FANCC):c.80C>T (p.Thr27Ile)	rs1489419613

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