List of variants in gene MLH1 reported as benign by Sema4, Sema4

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 29

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HGVS	dbSNP	gnomAD frequency
NM_000249.4(MLH1):c.655A>G (p.Ile219Val)	rs1799977	0.23048
NM_000249.4(MLH1):c.2152C>T (p.His718Tyr)	rs2020873	0.02345
NM_000249.4(MLH1):c.1039-8T>A	rs193922367	0.01153
NM_000249.4(MLH1):c.588+11G>C	rs4647258	0.00993
NM_000249.4(MLH1):c.1732-19T>A	rs77120160	0.00923
NM_000249.4(MLH1):c.1959G>T (p.Leu653=)	rs1800146	0.00913
NM_000249.4(MLH1):c.637G>A (p.Val213Met)	rs2308317	0.00818
NM_000249.4(MLH1):c.1038+51C>T	rs55986674	0.00582
NM_000249.4(MLH1):c.589-15C>T	rs55658850	0.00582
NM_000249.4(MLH1):c.1852A>G (p.Lys618Glu)	rs35001569	0.00399
NM_000249.4(MLH1):c.1963A>G (p.Ile655Val)	rs55907433	0.00297
NM_000249.4(MLH1):c.790+10A>G	rs182733777	0.00188
NM_000249.4(MLH1):c.2146G>A (p.Val716Met)	rs35831931	0.00143
NM_000249.4(MLH1):c.-7C>T	rs104894994	0.00115
NM_000249.4(MLH1):c.-28A>G	rs56198082	0.00110
NM_000249.4(MLH1):c.1217G>A (p.Ser406Asn)	rs41294980	0.00087
NM_000249.4(MLH1):c.1151T>A (p.Val384Asp)	rs63750447	0.00077
NM_000249.4(MLH1):c.375A>G (p.Ala125=)	rs1800144	0.00062
NM_000249.4(MLH1):c.1410-10T>G	rs372053184	0.00044
NM_000249.4(MLH1):c.702G>A (p.Glu234=)	rs35908749	0.00041
NM_000249.4(MLH1):c.977T>C (p.Val326Ala)	rs63751049	0.00037
NM_000249.4(MLH1):c.1321G>A (p.Ala441Thr)	rs63750365	0.00034
NM_000249.4(MLH1):c.1040C>A (p.Thr347Asn)	rs201541505	0.00017
NM_000249.4(MLH1):c.2101C>A (p.Gln701Lys)	rs63750114	0.00016
NM_000249.4(MLH1):c.1808C>G (p.Pro603Arg)	rs63750876	0.00009
NM_000249.4(MLH1):c.649C>T (p.Arg217Cys)	rs4986984	0.00007
NM_000249.4(MLH1):c.1743G>A (p.Pro581=)	rs567838745	0.00003
NM_000249.4(MLH1):c.1266C>T (p.Gly422=)	rs63750791
NM_000249.4(MLH1):c.1853A>C (p.Lys618Thr)	rs63750449

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