List of variants in gene INSR reported as uncertain significance by Eurofins NTD LLC (GA)

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 29

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HGVS	dbSNP	gnomAD frequency
NM_000208.4(INSR):c.2838C>G (p.Asp946Glu)	rs146588336	0.00145
NM_000208.4(INSR):c.2736G>A (p.Arg912=)	rs147125937	0.00134
NM_000208.4(INSR):c.2243C>T (p.Ser748Leu)	rs143523271	0.00116
NM_000208.4(INSR):c.190T>C (p.Leu64=)	rs144836032	0.00092
NM_000208.4(INSR):c.959C>T (p.Thr320Met)	rs138528064	0.00087
NM_000208.4(INSR):c.2970G>A (p.Pro990=)	rs41304772	0.00085
NM_000208.4(INSR):c.41T>C (p.Leu14Pro)	rs745857330	0.00047
NM_000208.4(INSR):c.2666G>A (p.Arg889Gln)	rs187282966	0.00046
NM_000208.4(INSR):c.151G>A (p.Glu51Lys)	rs140852238	0.00035
NM_000208.4(INSR):c.1179G>A (p.Gly393=)	rs140573575	0.00025
NM_000208.4(INSR):c.2665C>T (p.Arg889Trp)	rs76077021	0.00021
NM_000208.4(INSR):c.3193C>G (p.Leu1065Val)	rs56395521	0.00021
NM_000208.4(INSR):c.1665T>C (p.Ser555=)	rs149795690	0.00010
NM_000208.4(INSR):c.2256C>G (p.Ala752=)	rs376497490	0.00008
NM_000208.4(INSR):c.3042C>T (p.Asp1014=)	rs369686949	0.00006
NM_000208.4(INSR):c.1433G>A (p.Arg478His)	rs750676016	0.00005
NM_000208.4(INSR):c.1084G>A (p.Val362Ile)	rs72549237	0.00004
NM_000208.4(INSR):c.3111G>A (p.Val1037=)	rs761203697	0.00004
NM_000208.4(INSR):c.3805A>T (p.Met1269Leu)	rs375197837	0.00003
NM_000208.4(INSR):c.1810C>T (p.Arg604Trp)	rs777486535	0.00002
NM_000208.4(INSR):c.3158G>A (p.Arg1053His)	rs748109926	0.00002
NM_000208.4(INSR):c.1284T>C (p.Tyr428=)	rs794727776	0.00001
NM_000208.4(INSR):c.2327C>T (p.Thr776Met)	rs377048253	0.00001
NM_000208.4(INSR):c.2498G>A (p.Arg833Gln)	rs777565396	0.00001
NM_000208.4(INSR):c.3863A>G (p.Asn1288Ser)	rs756542405	0.00001
NM_000208.4(INSR):c.169G>A (p.Glu57Lys)	rs886044001
NM_000208.4(INSR):c.3165G>A (p.Ala1055=)	rs201445608
NM_000208.4(INSR):c.408G>A (p.Leu136=)	rs1568229079
NM_000208.4(INSR):c.653-9T>C	rs868296217

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